Thomas Theelen

Thomas Theelen wins CARIM PhD Award 2012

Wednesday March 7, four master students presented their project ideas to compete for a CARIM-funded PhD position. Thomas Theelen, Geert Hendrikx, Mike Jeurissen and Michael Rutjens all defended their project proposals. The jury ranked the presentation of Thomas Theelen as the winning proposal. 

The  project is aimed to investigate the central hypothesis that leaky adventitial and intraplaque microvessels lead to an acceleration of atherosclerosis. Data from Thomas' master internship indicate that Angiopoietin 1 gene transfer is able to normalize these leaky vessels towards a stable and quiescent phenotype. He will unravel the mechanisms of micro vascular permeability and their contribution to atherosclerosis, specifically the role of the endothelial junctions and the importance of vessel-surrounding pericytes.


Thomas will be invited to present his proposal - “Small vessels with huge impact - leaky microvessels exacerbate atherosclerosis.“ (Supervisors: Judith Sluimer) - at the Annual CARIM Symposium 2012. 

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