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Dekker Grant for Sam Heuts

Dekker Grant for Sam Heuts

25 July 2023

Dr Sam Heuts (Dept. of CTC) has received a Dekker grant awarded by the Dutch Heart Foundation.

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Harry Crijns Research Grant - Deadline 17 september 2023

Harry Crijns Research Grant - Deadline 17 september 2023

25 April 2023

De Harry Crijns Research Grant, in het leven geroepen door het Hart en vaat onderzoekfonds Limburg, in te stelle wordt periodiek toegekend aan jonge wetenschappers die zich bezighouden met klinisch cardiovasculair onderzoek en daarmee bijdragen aan de realisering van de doelstellingen van de foundation.

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Carim Maastricht
Carim Maastricht

Casper Schalkwijk

Professor

Prof. Casper Schalkwijk studied chemistry at University Utrecht and graduated in biochemistry. At the same university he obtained his PhD in 1992. He did post-graduate training in endothelial cell biology at TNO-PG in Leiden. He was appointed in 1995 as assistant professor and staff member at the Department of Clinical Chemistry at the Vrije Universiteit Medical Cente in Amsterdam and from 2004 as associate professor. He has led the Vascular Unit. He moved to the Department of Internal Medicine at Maastricht University in 2005, where he is heading the Laboratory for Metabolism and Vascular Medicine (~15fte). He was appointed as Professor of Experimental Internal Medicine at the Faculty of Health, Medicine and Life Sciences (FHML) of Maastricht UMC+ in 2011.

His main research themes are obesity, insulin resistance, endothelial function and vascular complications. The importance of endothelial dysfunction for the development of diabetic complications is studied in epidemiological setting with the availability of several cohorts and with experimental ex-vivo -, animal - and cell work. He has led several clinical studies. A major aim of his programme is to deliver specific and sensitive diagnostic biomarkers for the identification of patients developing  type 2 diabetes and to identify patients with high risk of vascular complications. Robust analytical techniques for measurements of biomarkers with multi-array technology and with UPLC-MSMS are available. A second aim of his programme is to obtain insight in the pathophysiology of vascular complications in diabetes. His current studies focus mainly on the importance non-enzymatic glycation for the development of diabetes and diabetic complications. He discovered, as one of the first, the link between AGEs and vascular complications in individuals with and without diabetes. He is an (inter)nationally recognised expert in the field of glycation. His lab is one of the most renowned labs in this field.The work has been supported by several grants and is now granted by the Diabetes Fonds Nederland, EFSD, NWO, ZonMw and NVWA.

Casper-schalkwijk

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 5.324
T: +31(0)43 388 21 86

  • 2023
    • Bednarska, K., Fecka, I., Scheijen, J. L. J. M., Ahles, S., Vangrieken, P., & Schalkwijk, C. G. (2023). A Citrus and Pomegranate Complex Reduces Methylglyoxal in Healthy Elderly Subjects: Secondary Analysis of a Double-Blind Randomized Cross-Over Clinical Trial. International Journal of Molecular Sciences, 24(17), Article 13168. https://doi.org/10.3390/ijms241713168
    • Mokhtar, S. B. A., van der Heide, F. C. T., Oyaert, K. A. M., van der Kallen, C. J. H., Berendschot, T. T. J. M., Scarpa, F., Colonna, A., de Galan, B. E., van Greevenbroek, M. M. J., Dagnelie, P. C., Schalkwijk, C. G., Nuijts, R. M. M. A., Schaper, N. C., Kroon, A. A., Schram, M. T., Webers, C. A. B., & Stehouwer, C. D. A. (2023). (Pre)diabetes and a higher level of glycaemic measures are continuously associated with corneal neurodegeneration assessed by corneal confocal microscopy: the Maastricht Study. Diabetologia. Advance online publication. https://doi.org/10.1007/s00125-023-05986-5
    • van der Heide, F. C. T., Khawaja, A., Berendschot, T. T. J. M., Littlejohns, T. J., Kuźma, E., Luben, R., Patel, P. J., Foster, P. J., Webers, C., Kroon, B., van der Kallen, C., van Dongen, M., Eussen, S., Schalkwijk, C., Bosma, H., Koehler, S., Schram, M., Blokland, G., Linden, D., ... Stehouwer, C. D. A. (2023). Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies. Alzheimer's & Dementia, Article 13167. Advance online publication. https://doi.org/10.1002/alz.13167
    • Bellini, S., Guarrera, S., Matullo, G., Schalkwijk, C., Stehouwer, C. D., Chaturvedi, N., Soedamah-Muthu, S. S., Barutta, F., & Gruden, G. (2023). Serum MicroRNA-191-5p Levels in Vascular Complications of Type 1 Diabetes: the EURODIAB Prospective Complications Study. Journal of Clinical Endocrinology & Metabolism. Advance online publication. https://doi.org/10.1210/clinem/dgad468
    • Linkens, A. M. A., Eussen, S. J. M. P., Houben, A. J. H. M., Mari, A., Dagnelie, P. C., Stehouwer, C. D. A., & Schalkwijk, C. G. (2023). Habitual intake of advanced glycation endproducts is not associated with worse insulin sensitivity, worse beta cell function, or presence of prediabetes or type 2 diabetes: The Maastricht Study. Clinical Nutrition, 42(8), 1491-1500. https://doi.org/10.1016/j.clnu.2023.05.021
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2023). Habitual Intake of Dietary Dicarbonyls is Associated with Greater Insulin Sensitivity and Lower Prevalence of Type 2 Diabetes: The Maastricht Study. American Journal of Clinical Nutrition, 118(1), 151-161. Advance online publication. https://doi.org/10.1016/j.ajcnut.2023.04.011
    • Berge, K., Aengevaeren, V. L., Mosterd, A., Velthuis, B. K., Lyngbakken, M. N., Omland, T., Schalkwijk, C. G., & Eijsvogels, T. M. H. (2023). Plasma Advanced Glycation End Products and Dicarbonyl Compounds Are Not Associated with Coronary Atherosclerosis in Athletes. Medicine and Science in Sports and Exercise, 55(7), 1143-1150. https://doi.org/10.1249/MSS.0000000000003152
    • Jin, S., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2023). Plasma factor D is cross-sectionally associated with low-grade inflammation, endothelial dysfunction and cardiovascular disease: The Maastricht study. Atherosclerosis, 377, 60-67. Advance online publication. https://doi.org/10.1016/j.atherosclerosis.2023.06.079
    • Lindhard, K., Jensen, B. L., Pedersen, B. L., Meyer-Olesen, C., Rix, M., Hansen, H. P., Schalkwijk, C., Waarenburg, M., Heaf, J., & Hansen, D. (2023). Far infrared treatment on the arteriovenous fistula induces changes in sVCAM and sICAM in patients on hemodialysis. Nephrology Dialysis Transplantation, 38(7), 1752-1760. Advance online publication. https://doi.org/10.1093/ndt/gfad032
    • Mokhtar, S. B. A., van der Heide, F. C. T., Oyaert, K. A. M., van der Kallen, C. J. H., Berendschot, T. T. J. M., Scarpa, F., Colonna, A., de Galan, B. E., van Greevenbroek, M. M. J., Schalkwijk, C. G., Nuijts, R. M. M. A., Schram, M. T., Webers, C. A. B., & Stehouwer, C. D. A. (2023). (Pre) diabetes and a higher level of glycemia are continuously associated with corneal neurodegeneration-The Maastricht Study. Acta Ophthalmologica, 101, 12-13.
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