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Uyên Châu Nguyên wins UM Dissertation Prize 2025

Uyên Châu Nguyên wins UM Dissertation Prize 2025

29 January 2026

During the Dies Natalis of Maastricht University, Uyên Châu Nguyên received the UM Dissertation Prize 2025.

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Global research network launched to study menopause and heart health

Global research network launched to study menopause and heart health

20 January 2026

Ten international health research funders, including the Dutch Heart Foundation, are investing $10 million in a new global research network to improve early prevention of cardiovascular disease in women. The initiative focuses on understanding how menopause affects heart health and how early intervention can reduce risk.

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Carim Maastricht
Carim Maastricht

Christian Weber

Professor

Prof. Christian Weber is the Chair in Vascular Medicine and the Director of the Institute for Cardiovascular Prevention at Ludwig-Maximilians-University (LMU) Munich, Germany, and Professor at the CARIM. After graduating and completing his training in internal medicine at LMU and Harvard Medical School, Boston, he was board-certified in clinical cardiology and appointed as a Chair in Molecular Cardiology at RWTH Aachen University. His group has a strong interest in the molecular interactions and patho-physiological functions of chemokines and immune cell subsets, as well as the role of microRNAs and their targets in vascular disease and atherosclerosis, while his clinical interests focus on developing novel biomarkers and biopharmaceuticals. He is the Spokesman of the DFG Collaborative Research Centre SFB1123 and coordinates the partner site Munich Heart Alliance in the German Centre for Cardiovascular Research (DZHK). Among numerous awards, he is a double ERC Advanced Investigator Grant recipient and Clarivate Analytics Highly Cited Researcher with more than 560 publications and an h-index of 97. He serves as the Editor-in-Chiefof Thrombosis&Haemostasis, Senior Associate Editor of Arteriosclerosis, Thrombosis & Vascular Biology andco-founderofCarolusTherapeutics Inc. and Cartesio Therapeutics Inc.

  • Vascular Immunotherapy, German Centre for Cardiovascular Research (BMBF DZHK
  • MHA VD1.2), 2019-2020
  • Munich Cluster for Systems Neurology (SyNergy), DFG Excellence Initiative, 2019-2026
  • ERC Advanced Grant °692511, PROVASC: Cell-specific vascular protection by CXCL12/CXCR4, 2016- 2022 ERC AdG
  • NIH 1R01HL122843, Molecular mechanisms linking CXCL12 to atherosclerosis, 2017-2020
  • DFG Collaborative Research Centre 1123 Atherosclerosis: new therapeutic targets, 2014-2022
Christian-weber

Department of Biochemistry
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2026
    • Li, Y., Leberzammer, J., Blanchet, X., Duan, R., Lacy, M., Triantafyllidou, V., Eckardt, V., Briem, E., Jung, A. S., Su, R., Guerra, J., Jansen, Y., Hristov, M., Enard, W., Bernhagen, J., Weber, C., Atzler, D., Bartelt, A., Doring, Y., ... Von Hundelshausen, P. (2026). Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation. Atherosclerosis, 413, Article 120608. https://doi.org/10.1016/j.atherosclerosis.2025.120608
    • Mohanta, S. K., Peng, L., Li, Y., Lu, S., Sun, T., Carnevale, L., Perrotta, M., Ma, Z., Forstera, B., Stanic, K., Zhang, C., Zhang, X., Szczepaniak, P., Bianchini, M., Saeed, B. R., Carnevale, R., Hu, D., Nosalski, R., Pallante, F., ... Habenicht, A. J. R. (2026). Author Correction: Neuroimmune cardiovascular interfaces control atherosclerosis. Nature, 649, E7. https://doi.org/10.1038/s41586-025-10043-9
  • 2025
    • Evans, B. R., Schulz, J., Triantafyllidou, V., Yerly, A., Thakur, M., Angliker, N., Siegrist, M., Jansen, Y., Yan, Y., Maas, S. L., Gold, C., Farina, F. M., Bayer, B., Bartelt, A., Weber, C., Wettich, J., Maegdefessel, L., Sachs, N., Schindewolf, M., ... Doering, Y. (2025). ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage-like foam cells in atherosclerosis. Cardiovascular Research. Advance online publication. https://doi.org/10.1093/cvr/cvaf258
    • Peters, L. J. F., Bidzhekov, K., Bonnin-Marquez, A., Sundararaman, S. S., Huchzermeier, R., Maas, S. L., Abschlag, K., Jans, A., Lin, C., Haberbosch, M., Jansen, Y., Yu, B., Sluimer, J. C., Gijbels, M. J., Jankowski, J., Bartneck, M., Biessen, E. A. L., Weber, C., Doring, Y., & Van Der Vorst, E. P. C. (2025). MicroRNA-26b<SUP>-/-</SUP> augments atherosclerosis, while mimic-loaded nanoparticles reduce atherogenesis. Cardiovascular Research, 121(17), 2700-2713. https://doi.org/10.1093/cvr/cvaf234
    • Mohanta, S. K., Heron, C., Klaus-Bergmann, A., Horstmann, H., Brakenhielm, E., Giannarelli, C., Habenicht, A. J. R., Gerhardt, H., & Weber, C. (2025). Metabolic and Immune Crosstalk in Cardiovascular Disease. Circulation Research, 136(11), 1433-1453. https://doi.org/10.1161/CIRCRESAHA.125.325496
    • Nageswaran, V., Carreras, A., Reinshagen, L., Beck, K. R., Steinfeldt, J., Henricsson, M., Ramezani Rad, P., Peters, L., Strässler, E. T., Lim, J., Verhaar, B., Döring, Y., Weber, C., König, M., Steinhagen-Thiessen, E., Demuth, I., Kränkel, N., Leistner, D. M., Potente, M., ... Haghikia, A. (2025). Gut Microbial Metabolite Imidazole Propionate Impairs Endothelial Cell Function and Promotes the Development of Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 45(5), 823-839. https://doi.org/10.1161/ATVBAHA.124.322346
    • Peters, L., Rakateli, L., Huchzermeier, R., Bonnin-Marquez, A., Maas, S. L., Lin, C., Jans, A., Geng, Y., Gorter, A., Gijbels, M., Rensen, S., Olinga, P., Hendrikx, T., Krawczyk, M., Brisbois, M., Jankowski, J., Bidzhekov, K., Weber, C., Biessen, E. A. L., ... van der Vorst, E. (2025). MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles. Elife, 13. https://doi.org/10.7554/eLife.97165
    • Asare, Y., Yan, G., Schlegl, C., Prestel, M., van der Vorst, E. P. C., Teunissen, A. J. P., Aronova, A., Tosato, F., Naser, N., Caputo, J., Prevot, G., Azzun, A., Wefers, B., Wurst, W., Schneider, M., Forne, I., Bidzhekov, K., Naumann, R., van der Laan, S. W., ... Dichgans, M. (2025). A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis. Immunity, 58(3), 555-567.e9. https://doi.org/10.1016/j.immuni.2025.01.003
    • El Bounkari, O., Zan, C., Yang, B., Ebert, S., Wagner, J., Bugar, E., Kramer, N., Bourilhon, P., Kontos, C., Zarwel, M., Sinitski, D., Milic, J., Jansen, Y., Kempf, W. E., Sachs, N., Maegdefessel, L., Ji, H., Gokce, O., Riols, F., ... Bernhagen, J. (2025). An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis. Nature Communications, 16(1), Article 2297. https://doi.org/10.1038/s41467-025-57540-z
    • Parma, L., Sachs, N., Sobczak, N., Li, Z., Merchant, K., Pauli, J., Depuydt, M. A. C., Wezel, A., Smeets, H. J., Bot, I., Sluetter, B., Maegdefessel, L., Weber, C., Duchene, J., & Megens, R. T. A. (2025). CXCL12 Derived From ACKR1<SUP>+</SUP> Intraplaque Neovessels Mediates CD8<SUP>+</SUP> T Cell Recruitment in Human Atherosclerosis. Circulation, 151(8), 581-584. https://doi.org/10.1161/CIRCULATIONAHA.124.072560
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