Dietbert Neumann

Associate professor

Dr Dietbert Neumann studied chemistry, as well as biology at the University of Cologne, Germany. After his double diploma, he worked at the NMI in Reutlingen Germany under the supervision of Dr T. Joos. Subsequently, he joined the lab of Prof. T. Wallimann at ETH Zurich. Dietbert received his doctorate with distinction and was awarded the ETH medal. After a short postdoctoral period in Oxford, UK, under the guidance of Prof. L. N. Johnson, he returned to ETH Zurich to complete his postdoctoral training, where he became Research Group Leader at the Institute of Cell Biology.

Since 2011, he is Associate Professor at Maastricht University. His research focus is on the integration of cellular metabolism into the protein kinase signalling network, in particular AMPK. Among his major achievements is the development of a method for bacterial production of the AMPK heterotrimer, a prerequisite for its structural investigation, which was consequently adopted by virtually all AMPK enthusiasts working in structural biology labs around the globe. Dietbert Neumann is also involved in coordination of various educational activities and teaches in biomedical courses using student-centered approaches. Furthermore, he initiated the ’European Workshop on AMPK’ conference series.

 

Department of Pathology
P. Debyelaan 25, 6229 HX Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 5.08
T: +31(0)43 387 71 67

  • 2021
    • Wang, S. J., Schianchi, F., Neumann, D., Wong, L. Y., Sun, A. M., van Nieuwenhoven, F. A., Zeegers, M. P., Strzelecka, A., Col, U., Glatz, J. F. C., Nabben, M., & Luiken, J. J. F. P. (2021). Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis. Molecular Metabolism, 53, [101293]. https://doi.org/10.1016/j.molmet.2021.101293
    • Sun, A., Simsek Papur, O., Dirkx, E., Wong, L., Sips, T., Wang, S., Strzelecka, A., Nabben, M., Glatz, J. F. C., Neumann, D., & Luiken, J. J. F. P. (2021). Phosphatidylinositol 4-kinase III beta mediates contraction-induced GLUT4 translocation and shows its anti-diabetic action in cardiomyocytes. Cellular and Molecular Life Sciences, 78(6), 2839-2856. https://doi.org/10.1007/s00018-020-03669-7
  • 2020
    • Schianchi, F., Glatz, J. F. C., Navarro Gascon, A., Nabben, M., Neumann, D., & Luiken, J. J. F. P. (2020). Putative Role of Protein Palmitoylation in Cardiac Lipid-Induced Insulin Resistance. International journal of molecular sciences, 21(24), [9438]. https://doi.org/10.3390/ijms21249438
    • Vervoorts, J., Neumann, D., & Luscher, B. (2020). The CCNY (cyclin Y)-CDK16 kinase complex: a new regulator of autophagy downstream of AMPK. Autophagy, 16(9), 1724-1726. https://doi.org/10.1080/15548627.2020.1795423
    • Luiken, J. J. F. P., Nabben, M., Neumann, D., & Glatz, J. F. C. (2020). Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1866(7), [165775]. https://doi.org/10.1016/j.bbadis.2020.165775
    • Dohmen, M., Krieg, S., Agalaridis, G., Zhu, X., Shehata, S. N., Pfeiffenberger, E., Amelang, J., Buetepage, M., Buerova, E., Pfaff, C. M., Chanda, D., Geley, S., Preisinger, C., Sakamoto, K., Lüscher, B., Neumann, D., & Vervoorts, J. (2020). AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy. Nature Communications, 11(1), [1032]. https://doi.org/10.1038/s41467-020-14812-0
    • Wang, S., Wong, L-Y., Neumann, D., Liu, Y., Sun, A., Antoons, G., Strzelecka, A., Glatz, J. F. C., Nabben, M., & Luiken, J. J. F. P. (2020). Augmenting Vacuolar H+-ATPase Function Prevents Cardiomyocytes from Lipid-Overload Induced Dysfunction. International journal of molecular sciences, 21(4), [1520]. https://doi.org/10.3390/ijms21041520
  • 2019
    • Zou, M-H., Kirkpatrick, S. S., Davis, B. J., Nelson, J. S., Wiles, W. G., Schlattner, U., Neumann, D., Brownlee, M., Freeman, M. B., & Goldman, M. H. (2019). Withdrawal: Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo : Role of mitochondrial reactive nitrogen species. Journal of Biological Chemistry, 294(36), 13525-13525. https://doi.org/10.1074/jbc.W119.010595
    • Neumann, D., & Viollet, B. (2019). AMP-Activated Protein Kinase Signalling. International journal of molecular sciences, 20(3), [766]. https://doi.org/10.3390/ijms20030766
    • Liu, Y., Rodriguez-Calvo, R., Wang, S., Zhu, X., Broers, J. L. V., Glatz, J. F. C., Luiken, J. J. F. P., & Neumann, D. (2019). Fluorescent labelling of membrane fatty acid transporter CD36 (SR-B2) in the extracellular loop. PLOS ONE, 14(1), [0210704]. https://doi.org/10.1371/journal.pone.0210704