Dominik Linz

Professor

Prof Dominik Linz is a clinician-scientist who received his PhD from Maastricht University, The Netherlands, in 2013 (Prof. U. Schotten) and completed his Cardiology training in Homburg/Saar, Germany, in 2017 (Prof. M. Böhm). In 2017, he was recruited as an Associate Professor and clinical EP-fellow to Adelaide to initiate and drive a translational research programme focussing on atrial fibrillation and sleep disordered breathing at the Royal Adelaide Hospital and University of Adelaide (Prof. P. Sanders). Since 2019, Dr Dominik Linz is a Staff member and consultant clinician at the Heart+Vascular Center, Maastricht UMC+.

Over the past years Prof. Dominik Linz has developed a National and International reputation in the field of cardiac arrhythmia research. The focus of this work has been to understand the pathophysiology and mechanisms underlying atrial arrhythmias and the development of treatment approaches. This research has broadly included: (i) Work describing sleep apnoea associated electrophysiological changes in the atria increasing atrial fibrillation susceptibility. (ii) Description of antiarrhythmic effects of autonomic modulation by renal sympathetic denervation under different pathophysiological conditions. (iii) Work describing the role of the lysosomal carboxypeptidase cathepsin A in the development of an atrial arrhythmogenic substrates. Ongoing research is mainly focused on risk factor modification and preventive interventions for AF.

As of January 2024, Dominik Linz (Department of Cardiology) has been appointed as a professor at Maastricht University. The title of his position is 'Comprehensive Atrial Fibrillation Management.

Department of Cardiology

 

  • 2026
    • Engels, M. D. E. A., Hermans, A. N. L., Hermans, B. J. M., Luermans, J., Chaldoupi, S.-M., Hendriks, J. M. L., Lankveld, T., Kessels, M. V. M., Vorstermans, B. J. G. H., Beukema, R. J., Vernooy, K., Heesen, W., & Linz, D. K. (2026). Smartphone application-based heart rhythm monitoring to cancel scheduled electrical cardioversion in patients with spontaneous conversion of presumed persistent atrial fibrillation: TeleConvert-AF. European Heart Journal - Digital Health, 7(2), Article ztaf140. https://doi.org/10.1093/ehjdh/ztaf140
    • Tönnis, T., Becher, N., Birkemeyer, R., Duncker, D., Eckardt, L., Gröschel, K., Linz, D., Meyer, C., Straube, F., Sultan, A., Wachter, R., Zylla, M., & Kirchhof, P. (2026). Device-detektiertes Vorhofflimmern – was nun? Executive Summary des DGK-Positionspapiers. Herzschrittmachertherapie und Elektrophysiologie, 37(1), 49-56. https://doi.org/10.1007/s00399-025-01112-7
    • Hermans, B. J., Farnir, F. I., Bijvoet, G. P., Larsen, B. S., Jespersen, T., Jerltorp, K., Holtackers, R. J., Mihl, C., Schotten, U., Vernooy, K., Luermans, J. G., Chaldoupi, S.-M., & Linz, D. (2026). Visualization of monopolar biphasic focal pulsed field ablation lesions 3 months after pulmonary vein isolation on high-resolution 3-dimensional dark-blood late gadolinium enhancement cardiac magnetic resonance images. Heart Rhythm, 23(2), 243-248. https://doi.org/10.1016/j.hrthm.2025.07.047
    • Marques, V. G., Gharaviri, A., Ozgul, O., Pezzuto, S., Auricchio, A., Vernooy, K., Linz, D., Hermans, B., Bonizzi, P., Zeemering, S., & Schotten, U. (2026). Ablation of atrial fibrillation sources identified through sequential high-density mapping: in silico comparison against anatomy-based approaches. EP Europace, 28(1), Article euaf304. https://doi.org/10.1093/europace/euaf304
    • Farnir, F. I. P., Chaldoupi, S.-M., Hermans, B., Johannessen, A., Haugdal, M. A., Ruwald, M. H., Tasnim Mohaissen, J. G. L. M., Saljic, A., Jerltorp, K., Nissen, S. D., Hertel, J. N., Farnir, F., Jespersen, T., Schotten, U., Luermans, J. G. L. M., Vernooy, K., Hansen, J., & Linz, D. (2026). Ablation of cavo-tricuspid isthmus dependent atrial flutter using a focal monopolar pulsed-field ablation catheter: Feasibility, periprocedural coronary spasms and conduction disorders. Heart Rhythm, 23(1), 105-113. https://doi.org/10.1016/j.hrthm.2025.07.001
    • Friderichsen, L. B. H., Larsen, B. S., Aplin, M., Host, N., Hadad, R., Christensen, L. M., Christensen, H., Havsteen, I., Bertelsen, L., Lund, M. A. V., Jespersen, T., Linz, D., & Sajadieh, A. (2026). Left atrial cardiomyopathy: association with atrial fibrillation and stroke recurrence. International Journal of Cardiovascular Imaging. https://doi.org/10.1007/s10554-026-03629-5
    • Linz, D., Hertel, J. N., Chaldoupi, S. M., Gil-Ramirez, A., Sattler, S. M., Linz, B., Farnir, F. I. P., Saljic, A., Mohaissen, T., Hermans, B. J. M., Ruwald, M. H., Luermans, J. G. L. M., Keelani, A., Geller, J. C., Raffa, S., Hansen, J., Jespersen, T., & Nissen, S. D. (2026). Monopolar biphasic focal pulsed field ablation directly at the atrioventricular junction and from within the noncoronary cusp: The PFA-CONDUCT study. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2026.01.012
    • Sandgren, E., Betz, K., Gawalko, M., Hermans, A., Habibi, Z., Verhaert, D., Philippens, S., Vorstermans, B., Kessesl, M., Hendriks, J. M., den Uijl, D., Chaldoupi, S. M., Luermans, J., Lankveld, T., Schotten, U., Vernooy, K., Rienstra, M., & Linz, D. (2026). Smartphone Application–Derived Clusters of Persistent Symptoms in Patients After Atrial Fibrillation Ablation: Data From the ISOLATION Study. JACC: Clinical Electrophysiology. Advance online publication. https://doi.org/10.1016/j.jacep.2025.12.013
    • Aerts, L., Kawczynski, M. J., Luermans, J., Bidar, E., Linz, D., Kowalewski, M., Lorusso, R., Pison, L., La Meir, M., Maesen, B., & Heuts, S. (2026). Effectiveness of Catheter and Standalone Surgical Ablation Procedures for Atrial Fibrillation: A Bayesian-Network Meta-analysis. Canadian Journal of Cardiology, 42(1), 136-148. https://doi.org/10.1016/j.cjca.2025.10.018
  • 2025
    • Gawalko, M., Kociemba, W., Sanders, P., & Linz, D. (2025). Gut microbiome and atrial fibrillation: mechanistic insights metabolites and comorbidities. Systematic review. Gut Microbes, 17(1), Article 2570423. https://doi.org/10.1080/19490976.2025.2570423