Dominik Linz

Academic Staff

Dr Dominik Linz is a clinician-scientist who received his PhD from Maastricht University, The Netherlands, in 2013 (Prof. U. Schotten) and completed his Cardiology training in Homburg/Saar, Germany, in 2017 (Prof. M. Böhm). In 2017, he was recruited as an Associate Professor and clinical EP-fellow to Adelaide to initiate and drive a translational research programme focussing on atrial fibrillation and sleep disordered breathing at the Royal Adelaide Hospital and University of Adelaide (Prof. P. Sanders). Since 2019, Dr Dominik Linz is a Staff member and consultant clinician at the Heart+Vascular Center, Maastricht UMC+.

Over the past years Dr Dominik Linz has developed a National and International reputation in the field of cardiac arrhythmia research. The focus of this work has been to understand the pathophysiology and mechanisms underlying atrial arrhythmias and the development of treatment approaches. This research has broadly included: (i) Work describing sleep apnoea associated electrophysiological changes in the atria increasing atrial fibrillation susceptibility. (ii) Description of antiarrhythmic effects of autonomic modulation by renal sympathetic denervation under different pathophysiological conditions. (iii) Work describing the role of the lysosomal carboxypeptidase cathepsin A in the development of an atrial arrhythmogenic substrates. Ongoing research is mainly focused on risk factor modification and preventive interventions for AF.

Department of Cardiology

 

  • 2023
    • Frausing, M. H. J. P., van de Lande, M. E., Maass, A. H., Nguyen, B. O., Hemels, M. E. W., Tieleman, R. G., Koldenhof, T., De Melis, M., Linz, D., Schotten, U., Weberndoerfer, V., Crijns, H. J. G. M., Van Gelder, I. C., Nielsen, J. C., & Rienstra, M. (2023). Brady- and tachyarrhythmias detected by continuous rhythm monitoring in paroxysmal atrial fibrillation. Heart, 109(17), 1286-1293. Advance online publication. https://doi.org/10.1136/heartjnl-2022-322253
    • Aydeniz, E., Weberndorfer, V., Brandts, L., Smulders, M. W., van Herpt, T. T. W., Martens, B., Vernooy, K., Linz, D., van der Horst, I. C. C., Wildberger, J. E., van Bussel, B. C. T., Driessen, R. G. H., & Mihl, C. (2023). Pericardial Fat Is Associated With Less Severe Multiorgan Failure Over Time in Patients With Coronavirus Disease-19: The Maastricht Intensive Care COVID Cohort. Journal of Thoracic Imaging. Advance online publication. https://doi.org/10.1097/RTI.0000000000000732
    • Shahrbabaki, S. S., Linz, D., & Baumert, M. (2023). Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events. International Journal of Cardiology, 385, 55-61. Advance online publication. https://doi.org/10.1016/j.ijcard.2023.05.047
    • Varma, N., Braunschweig, F., Burri, H., Hindricks, G., Linz, D., Michowitz, Y., Ricci, R. P., & Nielsen, J. C. (2023). Remote monitoring of cardiac implantable electronic devices and disease management. EP Europace, 25(9), Article euad233. https://doi.org/10.1093/europace/euad233
    • Hendriks, J. M., Lee, G., & Linz, D. (2023). Sleeping Beauty unravelled: Detection of sleep apnoea in patients with atrial fibrillation. IJC Heart and Vasculature, 47, Article 101237. https://doi.org/10.1016/j.ijcha.2023.101237
    • Verhaert, D. V. M., Linz, D., Wassink, G. F., Weijs, B., Philippens, S., Luermans, J. G. L. M., Westra, S. W., Schotten, U., Vernooy, K., & den Uijl, D. W. (2023). A new efficient and integrated pathway for patient evaluation prior to atrial fibrillation ablation. European Journal of Cardiovascular Nursing, 22(5), 498-505. Advance online publication. https://doi.org/10.1093/eurjcn/zvac095
    • van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383, 159-165. Advance online publication. https://doi.org/10.1016/j.ijcard.2023.04.024
    • Tilz, R. R., Schmidt, V., Pürerfellner, H., Maury, P., Chun, K. J., Martinek, M., Sohns, C., Schmidt, B., Mandel, F., Gandjbakhch, E., Laredo, M., Gunawardene, M. A., Willems, S., Beiert, T., Borlich, M., Iden, L., Füting, A., Spittler, R., Gaspar, T., ... Author collaboration (2023). A worldwide survey on incidence, management and prognosis of oesophageal fistula formation following atrial fibrillation catheter ablation: The POTTER-AF study. European Heart Journal, 44(27), 2458-2469. Advance online publication. https://doi.org/10.1093/eurheartj/ehad250
    • van der Velden, R. M. J., Hereijgers, M. J. M., Arman, N., van Middendorp, N., Franssen, F. M. E., Gawalko, M., Verhaert, D. V. M., Habibi, Z., Vernooy, K., Koltowski, L., Hendriks, J. M., Heidbuchel, H., Desteghe, L., Simons, S. O., & Linz, D. (2023). Implementation of a screening and management pathway for chronic obstructive pulmonary disease in patients with atrial fibrillation. EP Europace, 25(7), 1-10. Article euad193. https://doi.org/10.1093/europace/euad193
    • Tu, S. J., Gallagher, C., Elliott, A. D., Bradbury, K. E., Marcus, G. M., Linz, D., Pitman, B. M., Middeldorp, M. E., Hendriks, J. M., Lau, D. H., Sanders, P., & Wong, C. X. (2023). Associations of dietary patterns, ultra-processed food and nutrient intake with incident atrial fibrillation. Heart. Advance online publication. https://doi.org/10.1136/heartjnl-2023-322412