Eline Kooi

Professor

Prof. Eline Kooi obtained a Master degree in Physics (University of Amsterdam, 1995) and a PhD degree in Molecular Physics at the same university (1999). She was trained in Medical Physics, specialisation Radiology, at Maastricht UMC from 1999-2004. Since 2004 she is a registered Medical Physicist at Maastricht UMC+. Presently, she is a Professor of Medical Physics, especially vascular imaging, at the Department of Radiology and Nuclear Medicine within CARIM.

Her research is focussed on sophisticated multi-modality cardiovascular imaging. Her group is at the international forefront of developing and evaluating imaging techniques to study plaque vulnerability. She has focussed on cutting edge imaging of the hallmarks of high-risk plaques in animals and patients. She was the first to demonstrate that plaque inflammation can be visualised in humans. Her group has the unique position of multi-modality imaging of the vessel wall (PET/MRI, ultrasound, CT) in different vascular beds (carotid and coronary arteries, aorta). She has performed numerous MR Spectroscopy studies on lipid metabolism, also in the heart. Recently, she has expanded her research towards cardiac MRI (perfusion MRI, T1 mapping).

She is a leading member of the steering committee of a multi-centre trial to determine the clinical value of plaque imaging (PARISK) and she coordinates plaque imaging within the European Carotid Surgery Trial-2 (ECST-2). She has published >100 scientific publications in international peer-reviewed journals. She has successfully completed supervision of 12 PhD students. Currently, she is supervising 6 PhD students and one post-doc student. She is frequently invited as invited speaker and/or moderator at the leading international conferences in her field. She has received numerous research grants.

Department of Radiology and Nuclear Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H1.328
T: +31(0)43 387 49 11

 

  • 2020
    • Dweck, M. R., Maurovich-Horvat, P., Leiner, T., Cosyns, B., Fayad, Z. A., Gijsen, F. J. H., Van der Heiden, K., Kooi, M. E., Maehara, A., Muller, J. E., Newby, D. E., Narula, J., Pontone, G., Regar, E., Serruys, P. W., van der Steen, A. F. W., Stone, P. H., Waltenberger, J. L., Yuan, C., ... Back, M. (2020). Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology and the European Association of Cardiovascular Imaging. European Heart Journal Cardiovascular Imaging, 21(11), 1177-1183. https://doi.org/10.1093/ehjci/jeaa201
    • Saba, L., Moody, A. R., Saam, T., Kooi, M. E., Wasserman, B. A., Staub, D., van der Lugt, A., DeMarco, J. K., Saloner, D., Wintermark, M., & Gupta, A. (2020). Vessel Wall-Imaging Biomarkers of Carotid Plaque Vulnerability in Stroke Prevention Trials A Viewpoint From the Carotid Imaging Consensus Group. JACC-Cardiovascular Imaging, 13(11), 2445-2456. https://doi.org/10.1016/j.jcmg.2020.07.046
    • Kassem, M., Florea, A., Mottaghy, F. M., van Oostenbrugge, R., & Kooi, M. E. (2020). Magnetic resonance imaging of carotid plaques: current status and clinical perspectives. Annals of translational medicine, 8(19), [1266]. https://doi.org/10.21037/atm-2020-cass-16
    • Wouters, K., Kusters, Y. H. A. M., Bijnen, M., Wetzels, S., Zhang, X., Linssen, P. B. C., Gaens, K., Houben, A. J. H. M., Joris, P. J., Plat, J., Kooi, M. E., van der Kallen, C. J. H., Mensink, R. P., Verboven, K., Jocken, J., Hansen, D., Blaak, E. E., Ehlers, F. A. I., Wieten, L., ... Schalkwijk, C. G. (2020). NK cells in human visceral adipose tissue contribute to obesity-associated insulin resistance through low-grade inflammation. Clinical and Translational Medicine, 10(6), [192]. https://doi.org/10.1002/ctm2.192
    • Aizaz, M., Moonen, R. P. M., van der Pol, J. A. J., Prieto, C., Botnar, R. M., & Kooi, M. E. (2020). PET/MRI of atherosclerosis. Cardiovascular Diagnosis and Therapy, 10(4), 1120-1139. https://doi.org/10.21037/cdt.2020.02.09
    • Schindler, A., Schinner, R., Altaf, N., Hosseini, A. A., Simpson, R. J., Esposito-Bauer, L., Singh, N., Kwee, R. M., Kurosaki, Y., Yamagata, S., Yoshida, K., Miyamoto, S., Maggisano, R., Moody, A. R., Poppert, H., Kooi, M. E., Auer, D. P., Bonati, L. H., & Saam, T. (2020). Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques Meta-Analysis of Individual Patient Data. JACC-Cardiovascular Imaging, 13(2), 395-406. https://doi.org/10.1016/j.jcmg.2019.03.028
  • 2019
    • Simons, N., Debray, F-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2019). Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content. Journal of Clinical Endocrinology & Metabolism, 104(11), 5053-5061. https://doi.org/10.1210/jc.2018-02795
    • Wilson, D., Ambler, G., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martinez-Domeno, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., ... Werring, D. J. (2019). Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. Lancet Neurology, 18(7), 653-665. https://doi.org/10.1016/S1474-4422(19)30197-8
    • Telgenkamp, I., Kusters, Y. H. A. M., Schalkwijk, C. G., Houben, A. J. H. M., Kooi, M. E., Lindeboom, L., Bons, J. A. P., Schaper, N. C., Joris, P. J., Plat, J., Mensink, R. P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. Journal of Clinical Endocrinology & Metabolism, 104(7), 2719-2727. https://doi.org/10.1210/jc.2018-02378
    • van Dijk, A. C., Donkel, S. J., Zadi, T., Sonneveld, M. A. H., Schreuder, F. H. B. M., Chohan, M. F., Koudstaal, P. J., Leebeek, F. W. G., Saxena, R., Hendrikse, J., Kooi, M. E., van der Lugt, A., & de Maat, M. P. M. (2019). Association between fibrinogen and fibrinogen gamma ' and atherosclerotic plaque morphology and composition in symptomatic carotid artery stenosis: Plaque-At-RISK study. Thrombosis Research, 177, 130-135. https://doi.org/10.1016/j.thromres.2019.02.030