Eline Kooi


Prof. Eline Kooi obtained a Master degree in Physics (University of Amsterdam, 1995) and a PhD degree in Molecular Physics at the same university (1999). She was trained in Medical Physics, specialisation Radiology, at Maastricht UMC from 1999-2004. Since 2004 she is a registered Medical Physicist at Maastricht UMC+. Presently, she is a Professor of Medical Physics, especially vascular imaging, at the Department of Radiology and Nuclear Medicine within CARIM.

Her research is focussed on sophisticated multi-modality cardiovascular imaging. Her group is at the international forefront of developing and evaluating imaging techniques to study plaque vulnerability. She has focussed on cutting edge imaging of the hallmarks of high-risk plaques in animals and patients. She was the first to demonstrate that plaque inflammation can be visualised in humans. Her group has the unique position of multi-modality imaging of the vessel wall (PET/MRI, ultrasound, CT) in different vascular beds (carotid and coronary arteries, aorta). She has performed numerous MR Spectroscopy studies on lipid metabolism, also in the heart. Recently, she has expanded her research towards cardiac MRI (perfusion MRI, T1 mapping).

She is a leading member of the steering committee of a multi-centre trial to determine the clinical value of plaque imaging (PARISK) and she coordinates plaque imaging within the European Carotid Surgery Trial-2 (ECST-2). She has published >100 scientific publications in international peer-reviewed journals. She has successfully completed supervision of 12 PhD students. Currently, she is supervising 6 PhD students and one post-doc student. She is frequently invited as invited speaker and/or moderator at the leading international conferences in her field. She has received numerous research grants.

Department of Radiology and Nuclear Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H1.328
T: +31(0)43 387 49 11


  • 2024
    • Brandt, Y., Alers, R.-J., Canjels, L. P. W., Jorissen, L. M., Jansen, G., Janssen, E. B. N. J., van Kuijk, S., Went, T. M., Koehn, D., Gerretsen, S. C., Jansen, J., Backes, W., Hurks, P. P. M., van de Ven, V., Kooi, M. E., Spaanderman, M. E. A., & Ghossein-Doha, C. (2024). DEcreased Cognitive functiON, NEurovascular CorrelaTes and myocardial changes in women with a history of pre-eclampsia (DECONNECT): research protocol for a cross-sectional pilot study. BMJ Open, 14(3), Article 077534. https://doi.org/10.1136/bmjopen-2023-077534
    • Saba, L., Cau, R., Murgia, A., Nicolaides, A. N., Wintermark, M., Castillo, M., Staub, D., Kakkos, S., Yang, Q., Paraskevas, K. I., Yuan, C., Edjlali, M., Sanfilippo, R., Hendrikse, J., Johansson, E., Mossa-Basha, M., Balu, N., Dichgans, M., Saloner, D., ... Et al. (2024). Carotid Plaque-RADS, a novel stroke risk classification system. JACC-Cardiovascular Imaging, 17(1), 62-75. https://doi.org/10.1016/j.jcmg.2023.09.005
  • 2023
    • Camarasa, R., Kervadec, H., Kooi, M. E., Hendrikse, J., Nederkoorn, P. J., Bos, D., & de Bruijne, M. (2023). Nested star-shaped objects segmentation using diameter annotations. Medical Image Analysis, 90(1), Article 102934. https://doi.org/10.1016/j.media.2023.102934
    • Kassem, M., Crombag, G. A. J. C., Stegers, J., Liem, M. I., Koornstra, E., Schreuder, F. H. B. M., van Dam-Nolen, D. H. K., Lucci, C., van der Geest, R. J., Daemen, M. J., van der Steen, A. F. W., Hendrikse, J., Mess, W. H., Bos, D., Wildberger, J. E., van Oostenbruggeb, R. J., Nederkoorn, P. J., & Kooi, M. E. (2023). The association between antiplatelet therapy and changes in intraplaque hemorrhage in patients with mild to moderate symptomatic carotid stenosis: a longitudinal MRI study. Cerebrovascular Diseases. Advance online publication. https://doi.org/10.1159/000535274
    • Ren, Z., Bosma, H., Wesselius, A., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., Koster, A., van Greevenbroek, M. M. J., Dagnelie, P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Traditional lifestyle factors partly mediate the association of socioeconomic position with intrahepatic lipid content: The Maastricht study. JHEP Reports, 5(11), Article 100855. https://doi.org/10.1016/j.jhepr.2023.100855
    • Kassem, M., de Kam, S. S., van Velzen, T. J., van der Geest, R., Wagner, B., Sokolska, M., Pizzini, F. B., Nederkoorn, P. J., Rolf Jäger, H., Brown, M. M., van Oostenbrugge, R. J., Bonati, L. H., & Eline Kooi, M. (2023). Application of mask images of contrast-enhanced MR angiography to detect carotid intraplaque hemorrhage in patients with moderate to severe symptomatic and asymptomatic carotid stenosis. European Journal of Radiology, 168(1), Article 111145. https://doi.org/10.1016/j.ejrad.2023.111145
    • Alers, R.-J., Ghossein-Doha, C., Canjels, L. P. W., Muijtjens, E. S. H., Brandt, Y., Kooi, M. E., Gerretsen, S. C., Jansen, J. F. A., Backes, W. H., Hurks, P. P. M., van de Ven, V., & Spaanderman, M. E. A. (2023). Attenuated cognitive functioning decades after preeclampsia. American Journal of Obstetrics and Gynecology, 229(3), 294.e1-294.e14. https://doi.org/10.1016/j.ajog.2023.02.020
    • Kassem, M., Nies, K. P. H., Boswijk, E., van der Pol, J., Aizaz, M., Gijbels, M. J. J., Li, D., Bucerius, J., Mess, W. H., Wildberger, J. E., van Oostenbrugge, R. J., Moonen, R. P. M., Fan, Z., & Kooi, M. E. (2023). Quantification of carotid plaque composition with a multi-contrast atherosclerosis characterization (MATCH) MRI sequence. Frontiers in Cardiovascular Medicine, 10, Article 1227495. https://doi.org/10.3389/fcvm.2023.1227495
    • Canjels, L. P. W., Alers, R. J., van de Ven, V., Hurks, P. P. M., Gerretsen, S. C., Brandt, Y., Kooi, M. E., Jansen, J. F. A., Backes, W. H., Ghossein-Doha, C., & Spaanderman, M. E. A. (2023). Cerebral volume is unaffected after pre-eclampsia. Ultrasound in Obstetrics & Gynecology, 62(1), 115-121. https://doi.org/10.1002/uog.26172
    • Chemaly, M., Marlevi, D., Iglesias, M.-J., Lengquist, M., Kronqvist, M., Bos, D., van Dam-Nolen, D. H. K., van der Kolk, A., Hendrikse, J., Kassem, M., Matic, L., Odeberg, J., de Vries, M. R., Kooi, M. E., & Hedin, U. (2023). Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis. Biomolecules, 13(6), Article 882. https://doi.org/10.3390/biom13060882