Hans-Peter Brunner-La Rocca


Prof. Hans-Peter Brunner-La Rocca has graduated in medicine at the University of Zurich, Switzerland. He was trained in Internal Medicine and Cardiology in Switzerland. After doing a post-doc in Melbourne, Australia, for two years, he had been working as cardiologist and heart failure specialist in Zurich. In 2002, he moved to Basel, where he was responsible for the heart failure and heart transplant services. He has obtained his lecture qualification both in Zurich and in Basel and was announced as Professor in Basel Switzerland in 2008. Since 2009, he has been working at Maastricht UMC+ as Professor of Clinical Heart Failure. He is head of the heart failure clinic and head of the division of structural heart diseases.

He has been involved in numerous research projects since many years. In particular, he has a special interest in personalised medicine in heart failure using biomarkers and has successfully led international studies related to this topic. In addition, eHealth is an important focus of research. He has published >250 research articles.

He has been working as member of different working groups of the Heart Failure Association of the European Society of Cardiology and is board member of working group on heart failure in the Netherlands.

On the one hand, he is continuing his research on biomarker in heart failure for therapy guidance. He is collaborating internationally on this topic and is participating in several large international projects in this regard. On the other hand, he is leading an international consortium, aiming to develop a personalized eHealth application to enable patients with heart failure to perform self-care, i.e. including self-prescription of medication. Recently, the consortium received 4.4 M€ to support this project from INTERREG-NWE (budget Maastricht UMC+ > 2.0 M€).

He is additionally involved in national research projects (e.g. heart-brain connection, supported by CVON) and is the local PI of several large industry sponsored RCTs. In one of them, he is the national coordinator for the Netherlands.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.B2.031
T: +31(0)43 387 70 97

  • 2021
    • Marcks, N., Aimo, A., Januzzi, J. L., Vergaro, G., Clerico, A., Latini, R., Meessen, J., Anand, I. S., Cohn, J. N., Gravning, J., Ueland, T., Bayes-Genis, A., Lupón, J., de Boer, R. A., Yoshihisa, A., Takeishi, Y., Egstrup, M., Gustafsson, I., Gaggin, H. K., ... Brunner-La Rocca, H-P. (2021). Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data. Clinical research in cardiology. https://doi.org/10.1007/s00392-021-01822-1
  • 2020
    • Janssen, D. J. A., Ament, S. M. C., Boyne, J., Schols, J. M. G. A., Brunner-La Rocca, H-P., Maessen, J. M. C., & van den Beuken-van Everdingen, M. H. J. (2020). Characteristics for a tool for timely identification of palliative needs in heart failure: The views of Dutch patients, their families and healthcare professionals. European Journal of Cardiovascular Nursing, 19(8), 711-720. [1474515120918962]. https://doi.org/10.1177/1474515120918962
    • Verdonschot, J. A. J., Merken, J. J., van Stipdonk, A. M. W., Pliger, P., Derks, K. W. J., Wang, P., Henkens, M. T. H. M., van Paassen, P., Hamid, M. A. A., van Empel, V. P. M., Knackstedt, C., Luermans, J. G. L. M., Crijns, H. J. G. M., Brunner-La Rocca, H-P., Brunner, H. G., Poelzl, G., Vernooy, K., Heymans, S. R. B., & Hazebroek, M. R. (2020). Cardiac Inflammation Impedes Response to Cardiac Resynchronization Therapy in Patients With Idiopathic Dilated Cardiomyopathy. Circulation-Arrhythmia and Electrophysiology, 13(11), 1311-1320. [008727]. https://doi.org/10.1161/CIRCEP.120.008727
    • Breetveld, N. M., Alers, R-J., Geerts, L., van Kuijk, S. M. J., van Dijk, A. P., van der Vlugt, M. J., Heidema, W. M., van Neer, J., van Empel, V. P. M., Brunner-La Rocca, H-P., Scholten, R. R., Ghossein-Doha, C., & Spaanderman, M. E. A. (2020). Low Plasma Volume and Increased Pressure Load Relate to Concentric Left Ventricular Remodeling After Preeclampsia: A Longitudinal Study. Journal of the American Heart Association, 9(19), [015043]. https://doi.org/10.1161/JAHA.119.015043
    • Pellicori, P., Ferreira, J. P., Mariottoni, B., Brunner-La Rocca, H-P., Ahmed, F. Z., Verdonschot, J., Collier, T., Cuthbert, J. J., Petutschnigg, J., Mujaj, B., Girerd, N., Gonzalez, A., Clark, A. L., Cosmi, F., Staessen, J. A., Heymans, S., Latini, R., Rossignol, P., Zannad, F., & Cleland, J. G. F. (2020). Effects of spironolactone on serum markers of fibrosis in people at high risk of developing heart failure: rationale, design and baseline characteristics of a proof-of-concept, randomised, precision-medicine, prevention trial. The Heart OMics in AGing (HOMAGE) trial. European journal of heart failure, 22(9), 1711-1723. https://doi.org/10.1002/ejhf.1716
    • Henkens, M. T. H. M., Remmelzwaal, S., Robinson, E. L., van Ballegooijen, A. J., Aizpurua, A. B., Verdonschot, J. A. J., Raafs, A. G., Weerts, J., Hazebroek, M. R., Wijk, S. S., Handoko, M. L., den Ruijter, H. M., Lam, C. S. P., de Boer, R. A., Paulus, W. J., van Empel, V. P. M., Vos, R., Rocca, H-P. B-L., Beulens, J. W. J., & Heymans, S. R. B. (2020). Risk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review. European journal of heart failure, 22(9), 1586-1597. https://doi.org/10.1002/ejhf.1944
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J-L., Duarte, K., Bresso, E., Devignes, M-D., Andres, N. L., Girerd, N., Aakhus, S., Ambrosio, G., Rocca, H-P. B-L., Fontes-Carvalho, R., Fraser, A. G., van Heerebeek, L., de Keulenaer, G., Marino, P., ... Rossignol, P. (2020). Sex differences in circulating proteins in heart failure with preserved ejection fraction. Biology of Sex Differences, 11(1), [47]. https://doi.org/10.1186/s13293-020-00322-7
    • Ferro, D., van den Brink, H., Amier, R., van Buchem, M., de Bresser, J., Bron, E., Brunner-La Rocca, H-P., Hooghiemstra, A., Marcks, N., van Rossum, A., Biessels, G. J., & Heart-Brain Connection Consortium (2020). Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure. International Journal of Cardiology, 310, 96-102. https://doi.org/10.1016/j.ijcard.2020.04.032
    • Linssen, P. B. C., Brunner-La Rocca, H-P., Schalkwijk, C. G., Beulens, J. W. J., Elders, P. J. M., Van der Heijden, A. A., Slieker, R. C., Stehouwer, C. D. A., & Henry, R. M. A. (2020). Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study. International journal of molecular sciences, 21(14), [4944]. https://doi.org/10.3390/ijms21144944
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), [88]. https://doi.org/10.1186/s12933-020-01055-y