Harry Crijns


Harry Crijns is professor and chair of Cardiology and board member of the Cardiovascular Research Institute Maastricht (CARIM) at Maastricht UMC+. He studied medicine at the University of Amsterdam and was trained in cardiology and electrophysiology in Groningen and Maastricht. He is a Fellow of the ESC and a past board member of the EHRA. He is also past Chair of the Netherlands Society of Cardiology. He served on several guidelines committees for the management of AF. Currently he is the chairman of the scientific advisory board of the Dutch Heart Foundation.

His primary research focus continues to be atrial fibrillation (AF). He founded the RACE trials in the Netherlands and led the Euro Heart Survey on AF (ESC). He has established his reputation by introducing innovative concepts for diagnosis and treatment of AF by showing that - quite contrary to longstanding beliefs - electrical management does not change prognosis. This revolutionised management of the arrhythmia worldwide with the effect that major interventions like electrical cardioversion, catheter ablation and antiarrhythmic drug therapy are applied in a much more personalized fashion.

Subsequently his group showed that rate control in AF can be individualized thereby removing the previously used strict heart rate targets from the international guidelines. He also performed the Euro Heart Survey on AF and made many contributions to the field of stroke management in AF, such as the construction of well-recognised AF specific risk stratification scores for AF progression (HATCH), ischemic stroke (CHA2DS2-VASc) and major bleeding (HAS-BLED). These scores have practically conquered the medical AF community and improved patient care whilst boosting new clinical research throughout the world.

His research group now focusses on recent-onset AF, hybrid AF ablation, upstream therapy and vascular mechanisms for AF progression and stroke in idiopathic atrial fibrillation. He is (co-)author on over 650 scientific articles, with 56,677 citations and Hirsch-index of 100.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht

  • 2021
    • Dural, M., van Stipdonk, A. M. W., Salden, F. C. W. M., Ter Horst, I., Crijns, H. J. G. M., Meine, M., Maass, A. H., Kloosterman, M., & Vernooy, K. (2021). Association of ECG characteristics with clinical and echocardiographic outcome to CRT in a non-LBBB patient population. Journal of Interventional Cardiac Electrophysiology, 62(1), 9-19. https://doi.org/10.1007/s10840-020-00866-z
    • Rillig, A., Magnussen, C., Ozga, A. K., Suling, A., Brandes, A., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Eckardt, L., Elvan, A., Goette, A., Gulizia, M., Haegeli, L., Heidbuchel, H., Kuck, K. H., Ng, A., Szumowski, L., van Gelder, I., Wegscheider, K., & Kirchhof, P. (2021). Early Rhythm Control Therapy in Patients With Atrial Fibrillation and Heart Failure. Circulation, 144(11), 845-858. https://doi.org/10.1161/CIRCULATIONAHA.121.056323
    • Al-Jazairi, M. I. H., Nguyen, B. O., De With, R. R., Smit, M. D., Weijs, B., Hobbelt, A. H., Alings, M., Tijssen, J. G. P., Geelhoed, B., Hillege, H. L., Tieleman, R. G., Van Veldhuisen, D. J., Crijns, H. J. G. M., Van Gelder, I. C., Blaauw, Y., Rienstra, M., & RACE 3 Investigators (2021). Antiarrhythmic drugs in patients with early persistent atrial fibrillation and heart failure: results of the RACE 3 study. EP Europace, 23(9), 1359-1368. https://doi.org/10.1093/europace/euab062
    • Erkuner, O., Van Eck, M., Xhaet, O., Verheij, H., Neefs, J., Duygun, A., Nijmeijer, R., Said, S. A. M., Uiterwaal, H., Hagens, V., Bhagwandien, R., Szili-Torok, T., Bijsterveld, N., Tjeerdsma, G., Vijgen, J., Friart, A., Hoffer, E., Evrard, P., Srynger, M., ... Mairesse, G. H. (2021). Contemporary management of patients with atrial fibrillation in the Netherlands and Belgium: a report from the EORP-AF long-term general registry. Netherlands Heart Journal. https://doi.org/10.1007/s12471-021-01634-y
    • Mueller, P., Weijs, B., Bemelmans, N. M. A. A., Muegge, A., Eckardt, L., Crijns, H. J. G. M., Bax, J. J., Linz, D., & den Uijl, D. W. (2021). Echocardiography-derived total atrial conduction time (PA-TDI duration): risk stratification and guidance in atrial fibrillation management. Clinical research in cardiology. https://doi.org/10.1007/s00392-021-01917-9
    • Lisan, Q., van Sloten, T., Boutouyrie, P., Laurent, S., Danchin, N., Thomas, F., Guibout, C., Perier, M-C., Dagnelie, P., Henry, R. M., Schram, M. T., Heinzer, R., Marques-Vidal, P., van der Kallen, C. J., Crijns, H. J., van Greevenbroek, M., Reesink, K., Kohler, S., Sastry, M., ... Empana, J-P. (2021). Sleep Apnea is Associated With Accelerated Vascular Aging: Results From 2 European Community-Based Cohort Studies. Journal of the American Heart Association, 10(15), [021318]. https://doi.org/10.1161/JAHA.120.021318
    • Nedios, S., Lindemann, F., Heijman, J., Crijns, H. J. G. M., Bollmann, A., & Hindricks, G. (2021). Atrial remodeling and atrial fibrillation recurrence after catheter ablation: Past, present, and future developments. Herz, 46(4), 312-317. https://doi.org/10.1007/s00059-021-05050-1
    • de Vries, T. A. C., Hemels, M. E. W., Cools, F., Crijns, H. J. G. M., Yperzeele, L., Vanacker, P., Blankoff, I., Lancellotti, P., Mairesse, G. H., de Veer, A., Casado Arroyo, R., Catez, E., de Pauw, M., Vanassche, T., de Asmundis, C., Kirchhof, P., De Caterina, R., de Groot, J. R., & ETNA-AF-Europe principal investigators from Belgium and the Netherlands (2021). Characteristics of patients with atrial fibrillation prescribed edoxaban in Belgium and The Netherlands: insights from the ETNA-AF-Europe study. Acta Cardiologica, 76(4), 431-439. https://doi.org/10.1080/00015385.2020.1746095
    • Vroomen, M., van Rosmalen, F., Schroeder, J., Philippens, S., Delhaas, T., Crijns, H. J., & Pison, L. (2021). Ten-year follow-up after endocardial point-by-point cryoablation for paroxysmal atrial fibrillation. Acta Cardiologica, 76(4), 425-430. https://doi.org/10.1080/00015385.2020.1756087
    • Potpara, T. S., Lip, G. Y. H., Dagres, N., Crijns, H. J. M. G., Boriani, G., Kirchhof, P., Arbelo, E., Savelieva, I., Lenarczyk, R., Fauchier, L., Maggioni, A. P., Gale, C. P., & EORP-AF III Investigators Group (2021). Cohort profile: the ESC EURObservational Research Programme Atrial Fibrillation III (AF III) Registry. European heart journal. Quality of care & clinical outcomes, 7(3), 229-237. https://doi.org/10.1093/ehjqcco/qcaa050