Jan-Willem Sels

Assistant Professor

Dr Jan-Willem Sels received his medical degree from the University of Utrecht in 2002. He started clinical work at the Catharina Hospital Eindhoven where he started his training in cardiology in 2004. During this training he obtained his PhD at the Technical University Eindhoven in 2013. His dissertation was entitled: ”Markers of inducible myocardial ischemia in the systemic circulation”. After completion of his training in cardiology, he was additionally trained as an intensivist at the Maastricht UMC+. He currently works as a cardiologist and cardiologist-intensivist at both the Cardiology and Intensive Care Medicine departments of Maastricht UMC+.

Dr Sels is mainly involved in clinical work and management in a way that fosters collaboration within in various research projects. The research focus is on improving clinical cardiovascular care for critically ill patients, including topics such as extracorporeal life support and optimizing hemostasis in critical care. Dr Sels will therefore participate within the HEMOSUM community platform. As state above, he is a team player that likes to involve students, junior physicians and nurses in bedside teaching and critical appraisal of clinical science. He thereby aims to translate relevant clinical issues into practical science to improve patient monitoring and support. Dr Sels will therefore operate mainly on projects within advanced monitoring care, while providing careful clinical assistance for the PI group’s big data projects. 

Departments of Cardiology and Intensive Care
T: +31(0)43 387 6543

  • 2024
    • Hulshof, A. M., Nab, L., van Rosmalen, F., de Kok, J., Mulder, M. M. G., Hellenbrand, D., Sels, J. W. E. M., ten Cate, H., Cannegieter, S. C., Henskens, Y. M. C., & van Bussel, B. C. T. (2024). Rotational thromboelastometry as a biomarker for mortality — The Maastricht Intensive Care COVID cohort. Thrombosis Research, 234, 51-58. https://doi.org/10.1016/j.thromres.2023.12.010
    • de Kok, J. W. T. M., van Rosmalen, F., Koeze, J., Keus, F., van Kuijk, S. M. J., Castela Forte, J., Schnabel, R. M., Driessen, R. G. H., van Herpt, T. T. W., Sels, J.-W. E. M., Bergmans, D. C. J. J., Lexis, C. P. H., van Doorn, W. P. T. M., Meex, S. J. R., Xu, M., Borrat, X., Cavill, R., van der Horst, I. C. C., & van Bussel, B. C. T. (2024). Deep embedded clustering generalisability and adaptation for integrating mixed datatypes: two critical care cohorts. Scientific Reports, 14(1), Article 1045. https://doi.org/10.1038/s41598-024-51699-z
    • Simons, J., Di Mauro, M., Mariani, S., Ravaux, J., van der Horst, I. C. C., Driessen, R. G. H., Sels, J. W., Delnoij, T., Brodie, D., Abrams, D., Mueller, T., Taccone, F. S., Belliato, M., Broman, M. L., Malfertheiner, M. V., Boeken, U., Fraser, J., Wiedemann, D., Belohlavek, J., ... Lorusso, R. (2024). Bilateral Femoral Cannulation Is Associated With Reduced Severe Limb Ischemia-Related Complications Compared With Unilateral Femoral Cannulation in Adult Peripheral Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Registry. Critical Care Medicine, 52(1), 80-91. https://doi.org/10.1097/CCM.0000000000006040
  • 2023
    • Mulder, M. M. G., Schellens, J., Sels, J.-W. E. M., van Rosmalen, F., Hulshof, A.-M., de Vries, F., Segers, R., Mihl, C., van Mook, W. N. K. A., Bast, A., Spronk, H. M. H., Henskens, Y. M. C., van der Horst, I. C. C., ten Cate, H., Schurgers, L. J., Drent, M., & van Bussel, B. C. T. (2023). Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort. Journal of Intensive Care, 11(1), Article 63. https://doi.org/10.1186/s40560-023-00712-0
    • Schultinge, L., Hulshof, A. M., van Neerven, D., Mulder, M. M. G., Sels, J. W. E. M., Hulsewe, H. P. M. G., Kuiper, G. J. A. J. M., Olie, R. H., ten Cate, H., van der Horst, I. C. C., van Bussel, B. C. T., & Henskens, Y. M. C. (2023). Applications of rotational thromboelastometry in heparin monitoring in critical COVID-19 disease: Observations in the Maastricht Intensive Care COVID cohort. Thrombosis Update, 12(1), Article 100140. https://doi.org/10.1016/j.tru.2023.100140
  • 2022
    • Denessen, E. J., Heuts, S., Daemen, J. H., van Doorn, W. P., Vroemen, W. H., Sels, J.-W., Segers, P., Van't Hof, A. W., Maessen, J. G., Bekers, O., Van Der Horst, I. C., & Mingels, A. M. (2022). High-Sensitivity Cardiac Troponin I and T Kinetics Differ following Coronary Bypass Surgery: A Systematic Review and Meta-Analysis. Clinical Chemistry, 68(12), 1564-1575. Article hvac152. https://doi.org/10.1093/clinchem/hvac152
    • Bol, M. E., Huckriede, J. B., van de Pas, K. G. H., Delhaas, T., Lorusso, R., Nicolaes, G. A. F., Sels, J. E. M., & van de Poll, M. C. G. (2022). Multimodal measurement of glycocalyx degradation during coronary artery bypass grafting. Frontiers in medicine, 9, 1045728. https://doi.org/10.3389/fmed.2022.1045728
    • Bol, M. E., Broddin, B. E. K., Delhaas, T., Sels, J. E. M., & van de Poll, M. C. G. (2022). Variability of microcirculatory measurements in healthy volunteers. Scientific Reports, 12(1), Article 19887. https://doi.org/10.1038/s41598-022-22947-x
    • van de Berg, T. W., Mulder, M. M. G., Alnima, T., Nagy, M., van Oerle, R., Beckers, E. A. M., Hackeng, T. M., Hulshof, A. M., Sels, J. W. E. M., Henskens, Y. M. C., van der Horst, I. C. C., ten Cate, H., Spronk, H. M. H., van Bussel, B. C. T., & Dutch COVID & Thrombosis Coalition (2022). Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort. Frontiers in Cardiovascular Medicine, 9, Article 929284. https://doi.org/10.3389/fcvm.2022.929284
    • Ghossein, M. A., Driessen, R. G. H., van Rosmalen, F., Sels, J.-W. E. M., Delnoij, T., Geyik, Z., Mingels, A. M. A., van Stipdonk, A. M. W., Prinzen, F. W., Ghossein-Doha, C., van Kuijk, S. M. J., van der Horst, I. C. C., Vernooy, K., & van Bussel, B. C. T. (2022). Serial Assessment of Myocardial Injury Markers in Mechanically Ventilated Patients With SARS-CoV-2 (from the Prospective MaastrICCht Cohort). American Journal of Cardiology, 170, 118-127. https://doi.org/10.1016/j.amjcard.2022.01.030