Joost Lumens

Professor

Professor Joost Lumens studied Biomedical Engineering at the Eindhoven University of Technology where he obtained his MSc degree in Medical Engineering in 2005. He obtained his PhD degree in 2010 at Maastricht University (Dept. of Biomedical Engineering and Dept. of Physiology). During his PhD, he developed and validated a computational model of left-right ventricular interaction dynamics and applied it to study right ventricular failure in patients with pulmonary arterial hypertension. He continued his academic career as a post-doctoral fellow at the LIRYC Electrophysiology and Heart Modelling Institute of CHU de Bordeaux (France), where he combined computational, experimental and clinical data to unravel the working mechanisms of cardiac pacing therapies in the dyssynchronous failing heart.

Since 2012, he is working again at CARIM, where he leads the CircAdapt Research and Education team (www.circadapt.org). In 2021, he was appointed Professor of Computational Cardiology. His research team typically combines advanced computational modelling/simulation techniques with experimental and/or clinical data to gain mechanistic insight in cardiac diseases and their treatments. Importantly, translation of novel mechanistic insights into diagnostic, therapeutic and educational improvement is always pursued. Prof Joost Lumens received prestigious personal (Dutch Heart Foundation & NWO Vidi) and EU consortium funding (H2020 ERA-NET EraCoSysMed Joint Transnational Call 2015; ERA-CVD Joint Transnational Call 2018, coordinator of EMPATHY project; Marie Curie Intelligent Ultrasound, MARCIUS) for projects focussed on computational cardiac electro-mechanics and hemodynamics. He was the chairperson of the European Society of Cardiology (ESC) working group on e-Cardiology (2018-2020) and serves as deputy editor of the European Heart Journal – Digital Health.

Department of Biomedical Engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H3.362
T: +31(0)43 388 16 66

  • 2026
    • Buonocunto, M., Delhaas, T., Lyon, A., Heijman, J., & Lumens, J. (2026). Spatiotemporal determinants of stretch-activated channel-induced re-entry in ventricular tissue: An in-silico study. Journal of Molecular and Cellular Cardiology, 210, 150-164. https://doi.org/10.1016/j.yjmcc.2025.11.007
    • van den Acker, G. P. H., Dhont, S., van Loon, T., Churchill, T. W., Timmermans, F., Delhaas, T., Bertrand, P. B., & Lumens, J. (2026). Impact of left-heart myopathy on mitral valve stenosis assessment and interventional outcomes: an in-silico trial. European Heart Journal - Digital Health, 7(1), Article ztaf097. https://doi.org/10.1093/ehjdh/ztaf097
  • 2025
    • Prinzen, F. W., & Lumens, J. (2025). Atrioventricular Interval Modulation: Looking Beyond Blood Pressure Needed?JACC: Clinical Electrophysiology, 11(11), 2505-2508. https://doi.org/10.1016/j.jacep.2025.07.022
    • van Koll, J., Engels, M. D. E. A., Rijks, J. H. J., Salari, M., Luijten, J., Lumens, J., van Empel, V. P. M., Westra, S. W., van Stipdonk, A. M. W., Lankveld, T. A. R., Chaldoupi, S. M., Joza, J., Beukema, R. J., Luermans, J. G. L. M., Linz, D. K., & Vernooy, K. (2025). Long-term outcomes of pace-and-ablate strategy in patients with atrial fibrillation. Journal of Interventional Cardiac Electrophysiology, 68(7), 1487-1495. Article 100786. https://doi.org/10.1007/s10840-025-02038-3
    • Lee, X. A., Raschzok, S., Desjardins, J.-F., Van Loon, T., Plavetic, A., Kanny, O., Kabir, G., Nghiem, L., Dauz, J., Kapus, A., Lumens, J., Connelly, K. A., & Friedberg, M. K. (2025). Left ventricular pressure-loading improves pressure-induced right ventricular remodeling by redistributing mechanical load and reducing mechanosignaling. Physiological Reports, 13(18), Article e70546. https://doi.org/10.14814/phy2.70546
    • van Osta, N., van Loon, T., & Lumens, J. (2025). Individual hearts: computational models for improved management of cardiovascular disease. Heart. Advance online publication. https://doi.org/10.1136/heartjnl-2024-324177
    • Bruining, N., van der Boon, R., Kardys, I., Cummins, P., & Lumens, J. (2025). Reviewers and awards. European Heart Journal - Digital Health. Advance online publication. https://doi.org/10.1093/ehjdh/ztaf098
    • Mizner, J., Beela, A., Linkova, H., Vesela, J., Sussenbek, O., Stros, P., Smisek, R., Jurak, P., Leinveber, P., Lipoldova, J., Nagy, A., Waldauf, P., Lumens, J., Vernooy, K., Prinzen, F., & Curila, K. (2025). Electrical and mechanical interventricular dyssynchrony coupling in patients with bradycardia: A UHF-ECG validation trial. Heart Rhythm, 22(9), 2382-2390. https://doi.org/10.1016/j.hrthm.2025.02.031
    • Lempers, T. E. M., Smits, K. C., van Koll, J., Dural, M., van Stipdonk, A. M. W., Lumens, J., Luermans, J. G. L. M., Vernooy, K., Prinzen, F. W., van Dam, P., & Nguyên, U. C. (2025). An in-silico analysis of the influence of left bundle branch block and myocardial fibrosis on electrocardiographic QRS duration and morphology and vectorcardiographic QRS area. Journal of Electrocardiology, 91, Article 154043. https://doi.org/10.1016/j.jelectrocard.2025.154043
    • van Loon, T., Vernooy, K., & Lumens, J. (2025). Rate acceleration in heart failure with preserved ejection fraction: towards different strokes for different folks. European Heart Journal, 46(21), 2029-2030. https://doi.org/10.1093/eurheartj/ehaf110