Joost Lumens

Associate professor

Dr Joost Lumens studied Biomedical Engineering at the Eindhoven University of Technology where he obtained his MSc degree in Medical Engineering in 2005. He obtained his PhD degree in 2010 at Maastricht University (Dept. of Biomedical Engineering and Dept. of Physiology). During his PhD, he developed and validated a computational model of left-right ventricular interaction dynamics and applied it to study right ventricular failure in patients with pulmonary arterial hypertension. He continued his academic career as a post-doctoral fellow at the LIRYC Electrophysiology and Heart Modelling Institute of CHU de Bordeaux (France), where he currently holds a Visiting Professor position. In Bordeaux, he combined computational, experimental and clinical data to unravel the working mechanisms of cardiac pacing therapies in the dyssynchronous failing heart.

Since 2012, he is working again at the CARIM, where he leads the CircAdapt Research and Education team (www.circadapt.org). His research team typically combines advanced computational modeling/simulation techniques with experimental and/or clinical data to gain mechanistic insight in cardiac diseases and their treatments (e.g. cardiac resynchronisation therapy). Importantly, translation of novel mechanistic insights into diagnostic, therapeutic and educational improvement is always pursued. Dr Joost Lumens received prestigious personal (Dutch Heart Foundation & NWO Vidi) and EU consortium funding (H2020 ERA-NET EraCoSysMed Joint Transnational Call 2015; ERA-CVD Joint Transnational Call 2018, coordinator of EMPATHY project) for projects focussed on computational cardiac electro-mechanics and hemodynamics. He is the current chairperson of the European Society of Cardiology (ESC) working group on e-Cardiology (2018-2020).

 

Department of Biomedical Engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H3.362
T: +31(0)43 388 16 66

  • 2021
    • Augustin, C. M., Gsell, M. A. F., Karabelas, E., Willemen, E., Prinzen, F. W., Lumens, J., Vigmond, E. J., & Plank, G. (2021). A computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation. Computer Methods in Applied Mechanics and Engineering, 386, [114092]. https://doi.org/10.1016/j.cma.2021.114092
    • van Osta, N., Kirkels, F. P., van Loon, T., Koopsen, T., Lyon, A., Meiburg, R., Huberts, W., Cramer, M. J., Delhaas, T., Haugaa, K. H., Teske, A. J., & Lumens, J. (2021). Uncertainty Quantification of Regional Cardiac Tissue Properties in Arrhythmogenic Cardiomyopathy Using Adaptive Multiple Importance Sampling. Frontiers in physiology, 12, [738926]. https://doi.org/10.3389/fphys.2021.738926
    • Lumens, J., Koopsen, T., & Beela, A. S. (2021). What Do We Gain From Septal Strain?JACC-Cardiovascular Imaging, 14(9), 1703-1706. https://doi.org/10.1016/j.jcmg.2021.05.010
    • Munneke, A. G., Lumens, J., & Delhaas, T. (2021). Cardiovascular fetal-to-neonatal transition: an in silico model. Pediatric Research. https://doi.org/10.1038/s41390-021-01401-0
    • Lyon, A., van Mourik, M., Cruts, L., Heijman, J., Bekkers, S. C. A. M., Schotten, U., Crijns, H. J. G. M., Linz, D., & Lumens, J. (2021). Both beat-to-beat changes in RR-interval and left ventricular filling time determine ventricular function during atrial fibrillation. EP Europace, 23, I21-I28. https://doi.org/10.1093/europace/euaa387
    • van Osta, N., Kirkels, F., Lyon, A., Koopsen, T., van Loon, T., Cramer, M-J., Teske, A. J., Delhaas, T., & Lumens, J. (2021). Electromechanical substrate characterization in arrhythmogenic cardiomyopathy using imaging-based patient-specific computer simulations. EP Europace, 23, I153-I160. https://doi.org/10.1093/europace/euaa407
  • 2020
    • Sutanto, H., Lyon, A., Lumens, J., Schotten, U., Dobrev, D., & Heijman, J. (2020). Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies. Progress in Biophysics & Molecular Biology, 157, 54-75. https://doi.org/10.1016/j.pbiomolbio.2020.02.008
    • Prinzen, F. W., & Lumens, J. (2020). Investigating myocardial work as a CRT response predictor is not a waste of work. European Heart Journal, 41(39), 3824-3826. https://doi.org/10.1093/eurheartj/ehaa677
    • Dilaveris, P., Casado-Arroyo, R., & Lumens, J. (2020). A roadmap to nationwide monitoring of Cardiovascular Implantable Electronic Devices in Greece: staying safe in the era of COVID-19 pandemic. Hellenic Journal of Cardiology, 61(6), 396-397. https://doi.org/10.1016/j.hjc.2020.09.008
    • Lyon, A., Dupuis, L. J., Arts, T., Crijns, H. J. G. M., Prinzen, F. W., Delhaas, T., Heijman, J., & Lumens, J. (2020). Differentiating the effects of β-adrenergic stimulation and stretch on calcium and force dynamics using a novel electromechanical cardiomyocyte model. American Journal of Physiology-heart and Circulatory Physiology, 319(3), H519-H530. https://doi.org/10.1152/ajpheart.00275.2020