Koen Reesink

Assistant Professor

Dr Koen Reesink was originally trained in Electrical Engineering and has been active in biomedical research for over 20 years. His interests and specialties are vascular structure and function, ventricular-vascular hemodynamic interaction, system dynamics and signal processing. Dr Reesink’s group has made significant and awarded contributions to quantify and interpret arterial stiffness measurements, especially in clinical settings. Reesink leads his research line ‘Constitutive and system characteristics of large arteries’ within in the CARIM programme 'Complex Arrhythmias' (PI Prof. Tammo Delhaas).

Dr Reesink contributes actively to research organisational development, as initiator/chair of the Vascular Network Group, as steering group member of the CARIM Muroidean Facility, and as chair of the Operational Excellence project MF2BMC around the new Biomedical Center (BMC) for animal research in Maastricht.

Dr Reesink’s current research line ‘Constitutive and system characteristics of large arteries’ is focussed on unravelling the multi-scale structure-function relations that underlie the pathophysiology of accelerated arterial stiffening. Quantitative insights into these relations are of utmost importance to conceive, develop and validate therapeutic approaches for de-stiffening arteries, in order to combat the growing epidemic of ‘old-age’ systolic hypertension and its desastrous cardiovascular and societal sequelae.

Reesink is currently involved in the EU H2020 Demonstrator project CARDIS (as WP co-lead), and in the EU grant proposals MSCA-ITN-EJD2019 MINDSHIFT (as coordinator) and COST VascAge (as participant).

Department of Biomedical Engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H3.360
T: +31(0)43 388 16 59

  • 2021
    • Beutel, F., Van Hoof, C., Rottenberg, X., Reesink, K., & Hermeling, E. (2021). Pulse Arrival Time Segmentation Into Cardiac and Vascular Intervals - Implications for Pulse Wave Velocity and Blood Pressure Estimation. Ieee Transactions on Biomedical Engineering, 68(9), 2810-2820. https://doi.org/10.1109/TBME.2021.3055154
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Goezinne, F., Liesenborghs, I., Dagnelie, P. C., Schaper, N. C., Kroon, A. A., Henry, R. M. A., Reesink, K. D., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2021). Vascular risk factors for optical coherence tomography-detected macular cysts: The Maastricht Study. Acta Ophthalmologica, e860-e868. https://doi.org/10.1111/aos.14677
    • Lisan, Q., van Sloten, T., Boutouyrie, P., Laurent, S., Danchin, N., Thomas, F., Guibout, C., Perier, M-C., Dagnelie, P., Henry, R. M., Schram, M. T., Heinzer, R., Marques-Vidal, P., van der Kallen, C. J., Crijns, H. J., van Greevenbroek, M., Reesink, K., Kohler, S., Sastry, M., ... Empana, J-P. (2021). Sleep Apnea is Associated With Accelerated Vascular Aging: Results From 2 European Community-Based Cohort Studies. Journal of the American Heart Association, 10(15), [021318]. https://doi.org/10.1161/JAHA.120.021318
    • van der Heide, F. C. T., Zhou, T. L., Henry, R. M. A., Houben, A. J. H. M., Kroon, A. A., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., Schram, M. T., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Koster, A., Savelberg, H. H. C. M., Schaper, N. C., Reesink, K. D., & Stehouwer, C. D. A. (2021). Carotid stiffness is associated with retinal microvascular dysfunction- The Maastricht Study. Microcirculation, 28(6), [e12702]. https://doi.org/10.1111/micc.12702
    • Foreman, Y. D., van Doorn, W. P. T. M., Schaper, N. C., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Henry, R. M. A., Koster, A., Eussen, S. J. P. M., Wesselius, A., Reesink, K. D., Schram, M. T., Dagnelie, P. C., Kroon, A. A., Brouwers, M. C. G. J., & Stehouwer, C. D. A. (2021). Greater daily glucose variability and lower time in range assessed with continuous glucose monitoring are associated with greater aortic stiffness: The Maastricht Study. Diabetologia, 64(8), 1880-1892. https://doi.org/10.1007/s00125-021-05474-8
    • Parikh, S., Ganizada, B., Debeij, G., Natour, E., Maessen, J., Spronck, B., Schurgers, L., Delhaas, T., Huberts, W., Bidar, E., & Reesink, K. (2021). Intra-Operative Video-Based Measurement of Biaxial Strains of the Ascending Thoracic Aorta. Biomedicines, 9(6), [670]. https://doi.org/10.3390/biomedicines9060670
    • Tanghe, A., Celie, B., Shadid, S., Rietzschel, E., Op't Roodt, J., Reesink, K. D., Heyman, E., & Calders, P. (2021). Acute Effects of Cocoa Flavanols on Blood Pressure and Peripheral Vascular Reactivity in Type 2 Diabetes Mellitus and Essential Hypertension: A Protocol for an Acute, Randomized, Double-Blinded, Placebo-Controlled Cross-Over Trial. Frontiers in cardiovascular medicine, 8, [602086]. https://doi.org/10.3389/fcvm.2021.602086
    • Zhou, T. L., Kroon, A. A., Henry, R. M. A., Koster, A., Dagnelie, P. C., Bosma, H., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Wesselius, A., Reesink, K. D., Kohler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2021). Exercise SBP response and incident depressive symptoms: The Maastricht Study. Journal of Hypertension, 39(3), 494-502. https://doi.org/10.1097/HJH.0000000000002657
    • Hulman, A., Foreman, Y. D., Brouwers, M. C. G. J., Kroon, A. A., Reesink, K. D., Dagnelie, P. C., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Faerch, K., Vistisen, D., Jorgensen, M. E., Stehouwer, C. D. A., & Witte, D. R. (2021). Towards precision medicine in diabetes? A critical review of glucotypes. Plos Biology, 19(3), [3000890]. https://doi.org/10.1371/journal.pbio.3000890
    • Panteleev, M. A., Korin, N., Reesink, K. D., Bark, D. L., Cosemans, J. M. E. M., Gardiner, E. E., & Mangin, P. H. (2021). Wall shear rates in human and mouse arteries: Standardization of hemodynamics for in vitro blood flow assays: Communication from the ISTH SSC subcommittee on biorheology. Journal of Thrombosis and Haemostasis, 19(2), 588-595. https://doi.org/10.1111/jth.15174