Koen Reesink

Assistant Professor

Dr Koen Reesink was originally trained in Electrical Engineering and has been active in biomedical research for over 20 years. His interests and specialties are vascular structure and function, ventricular-vascular hemodynamic interaction, system dynamics and signal processing. Dr Reesink’s group has made significant and awarded contributions to quantify and interpret arterial stiffness measurements, especially in clinical settings. Reesink leads his research line ‘Constitutive and system characteristics of large arteries’ within in the CARIM programme 'Complex Arrhythmias' (PI Prof. Tammo Delhaas).

Dr Reesink contributes actively to research organisational development, as initiator/chair of the Vascular Network Group, as steering group member of the CARIM Muroidean Facility, and as chair of the Operational Excellence project MF2BMC around the new Biomedical Center (BMC) for animal research in Maastricht.

Dr Reesink’s current research line ‘Constitutive and system characteristics of large arteries’ is focussed on unravelling the multi-scale structure-function relations that underlie the pathophysiology of accelerated arterial stiffening. Quantitative insights into these relations are of utmost importance to conceive, develop and validate therapeutic approaches for de-stiffening arteries, in order to combat the growing epidemic of ‘old-age’ systolic hypertension and its desastrous cardiovascular and societal sequelae.

Reesink is currently involved in the EU H2020 Demonstrator project CARDIS (as WP co-lead), and in the EU grant proposals MSCA-ITN-EJD2019 MINDSHIFT (as coordinator) and COST VascAge (as participant).

Department of Biomedical Engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H3.360
T: +31(0)43 388 16 59

  • 2023
    • Malik, A. E. F., Giudici, A., van der Laan, K. W. F., Op 't Roodt, J., Mess, W. H., Delhaas, T., Spronck, B., & Reesink, K. D. (2023). Detectable Bias between Vascular Ultrasound Echo-Tracking Systems: Relevance Depends on Application. Journal of Clinical Medicine, 12(1), [69]. https://doi.org/10.3390/jcm12010069
  • 2022
    • Jin, S., Reesink, K. D., Kroon, A. A., de Galan, B., van der Kallen, C. J. H., Wesselius, A., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study. Journal of Hypertension, 40(11), 2161-2170. https://doi.org/10.1097/HJH.0000000000003237
    • Janssen, E. B. N. J., Hooijschuur, M. C. E., Lopes van Balen, V. A., Morina-Shijaku, E., Spaan, J. J., Mulder, E. G., Hoeks, A. P., Reesink, K. D., van Kuijk, S. M. J., Van't Hof, A., van Bussel, B. C. T., Spaanderman, M. E. A., & Ghossein-Doha, C. (2022). No accelerated arterial aging in relatively young women after preeclampsia as compared to normotensive pregnancy. Frontiers in cardiovascular medicine, 9, [911603]. https://doi.org/10.3389/fcvm.2022.911603
    • Veugen, M. G. J., Onete, V. G., Henry, R. M. A., Brunner-La Rocca, H-P., Koster, A., Dagnelie, P. C., Schaper, N. C., Sep, S. J. S., van der Kallen, C. J. H., van Boxtel, M. P. J., Reesink, K. D., Schouten, J. S., Savelberg, H. H. C. M., Köhler, S., Verhey, F. R., van den Bergh, J. P. W., Schram, M. T., & Stehouwer, C. D. A. (2022). Health burden in type 2 diabetes and prediabetes in The Maastricht Study. Scientific Reports, 12(1), 1-11. [7337]. https://doi.org/10.1038/s41598-022-11136-5
    • van der Laan, K. W. F., Reesink, K. D., van der Bruggen, M. M., Jaminon, A. M. G., Schurgers, L. J., Megens, R. T. A., Huberts, W., Delhaas, T., & Spronck, B. (2022). Improved Quantification of Cell Density in the Arterial Wall-A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy. Frontiers in physiology, 12, [814434]. https://doi.org/10.3389/fphys.2021.814434
  • 2021
    • Malik, A. E. F., Delhaas, T., Spronck, B., Henry, R. M. A., Joseph, J., Stehouwer, C. D. A., Mess, W. H., & Reesink, K. D. (2021). Single M-Line Is as Reliable as Multiple M-Line Ultrasound for Carotid Artery Screening. Frontiers in physiology, 12, [787083]. https://doi.org/10.3389/fphys.2021.787083
    • Giudici, A., Khir, A. W., Reesink, K. D., Delhaas, T., & Spronck, B. (2021). Five years of cardio-ankle vascular index (CAVI) and CAVI0: how close are we to a pressure-independent index of arterial stiffness?Journal of Hypertension, 39(11), 2128-2138. https://doi.org/10.1097/HJH.0000000000002928
    • van der Bruggen, M. M., Spronck, B., Delhaas, T., Reesink, K. D., & Schalkwijk, C. G. (2021). The Putative Role of Methylglyoxal in Arterial Stiffening: A Review. Heart Lung and Circulation, 30(11), 1681-1693. https://doi.org/10.1016/j.hlc.2021.06.527
    • Beutel, F., Van Hoof, C., Rottenberg, X., Reesink, K., & Hermeling, E. (2021). Pulse Arrival Time Segmentation Into Cardiac and Vascular Intervals - Implications for Pulse Wave Velocity and Blood Pressure Estimation. Ieee Transactions on Biomedical Engineering, 68(9), 2810-2820. https://doi.org/10.1109/TBME.2021.3055154