Marleen van Greevenbroek

Associate professor

Dr Marleen van Greevenbroek is Medical Biologist (University of Utrecht, 1992) and Epidemiologist (Maastricht University, 2012). She received her PhD degree in 1997 at the University of Utrecht, on a thesis concerning the effects of fatty acids on the production of intestinal triglyceride-rich lipoproteins. In September 1997, she was appointed at the University of Maastricht (Dept. of Internal Medicine), where she was involved in studies on the metabolic and genetic aspects of obesity and cardiometabolic diseases.

Her main area of research is the identification of early events in the development of insulin resistance, type 2 diabetes, and cardiovascular disease. In recent years, her research activities specifically focused on the role of the complement system herein. This research encompasses both cohort studies and experimental work.


Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2024
    • van der Heide, F. C. T., Steens, I. L. M., Limmen, B., Mokhtar, S., van Boxtel, M. P. J., Schram, M. T., Köhler, S., Kroon, A. A., van der Kallen, C. J. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., Koster, A., van Sloten, T. T., Jansen, J. F. A., Backes, W. H., & Stehouwer, C. D. A. (2024). Thinner inner retinal layers are associated with lower cognitive performance, lower brain volume, and altered white matter network structure-The Maastricht Study. Alzheimer's & Dementia, 316-329.
  • 2023
    • Ren, Z., Bosma, H., Wesselius, A., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., Koster, A., van Greevenbroek, M. M. J., Dagnelie, P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Traditional lifestyle factors partly mediate the association of socioeconomic position with intrahepatic lipid content: The Maastricht study. JHEP Reports, 5(11), Article 100855.
    • Feng, L., Ye, Z., Mo, C., Wang, J., Liu, S., Gao, S., Ke, H., Canida, T. A., Pan, Y., Greevenbroek, M. M. J. V., Houben, A. J. H. M., Wang, K., Hatch, K. S., Ma, Y., Lei, D. K. Y., Chen, C., Mitchell, B. D., Hong, L. E., Kochunov, P., ... Ma, T. (2023). Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK Biobank. Journal of Hypertension, 41(11), 1811-1820.
    • Mokhtar, S. B. A., van der Heide, F. C. T., Oyaert, K. A. M., van der Kallen, C. J. H., Berendschot, T. T. J. M., Scarpa, F., Colonna, A., de Galan, B. E., van Greevenbroek, M. M. J., Dagnelie, P. C., Schalkwijk, C. G., Nuijts, R. M. M. A., Schaper, N. C., Kroon, A. A., Schram, M. T., Webers, C. A. B., & Stehouwer, C. D. A. (2023). (Pre)diabetes and a higher level of glycaemic measures are continuously associated with corneal neurodegeneration assessed by corneal confocal microscopy: the Maastricht Study. Diabetologia, 66(11), 2030-2041.
    • Bellos, I., Marinaki, S., Lagiou, P., Boletis, I. N., Stehouwer, C. D. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., de Galan, B. E., Savelberg, H. H. C. M., Koster, A., Wesselius, A., & Benetou, V. (2023). Association of physical activity with endothelial dysfunction among adults with and without chronic kidney disease: The Maastricht Study. Atherosclerosis, 383(1), Article 117330.
    • Zhang, Y., Guloksuz, S., Stehouwer, C., Greevenbroek, M., Kohler, S., Eussen, S., Bosma, H., Boxtel, M., Schram, M., Linden, D., Rutten, B., & Blokland, G. (2023). The Additive Value Of Brain Lifestyle In The Explanatory Ability Of Polygenic Risk Profiles On Cognitive Performance In Aging Individuals. European Neuropsychopharmacology, 75, S169-S170.
    • Albers, J. D., Meertens, R. M., Savelberg, H. H. C. M., Köhler, S., Wesselius, A., Schram, M. T., Stehouwer, C. D. A., de Galan, B. E., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Eussen, S. J. P. M., Bosma, H., Schaper, N. C., & Koster, A. (2023). Both short and long sleep durations are associated with type 2 diabetes, independent from traditional lifestyle risk factors-The Maastricht Study. Sleep Health, 9(5), 733-741.
    • Erdős, B., Van sloun, B., Goossens, G. H., O’donovan, S. D., De galan, B. E., Van greevenbroek, M. M. J., Stehouwer, C. D. A., Schram, M. T., Blaak, E. E., Adriaens, M. E., Van riel, N. A. W., & Arts, I. C. W. (2023). Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study. PLOS ONE, 18(7), Article e0285820.
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2023). Habitual Intake of Dietary Dicarbonyls is Associated with Greater Insulin Sensitivity and Lower Prevalence of Type 2 Diabetes: The Maastricht Study. American Journal of Clinical Nutrition, 118(1), 151-161.
    • Jin, S., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2023). Plasma factor D is cross-sectionally associated with low-grade inflammation, endothelial dysfunction and cardiovascular disease: The Maastricht study. Atherosclerosis, 377(1), 60-67.