Matthijs Blankesteijn

Associate professor

Dr Matthijs Blankesteijn is associate professor of Pharmacology and Principal Investigator at CARIM. He obtained Master degrees in Biology and Chemistry from the Radboud University Nijmegen (1988), followed by a PhD degree from the same university in 1993. He then joined the Pharmacology department of Maastricht University as a post-doc, and after a postdoctoral training in Harvard Medical School in Boston in 1997-1998 (supervisor Prof. V. Dzau), he returned to the Department of Pharmacology as a staff member. For his research, he has received funding from ZonMw, NHS and FES, including a Vidi grant in 2003. He has published over 60 Wi-1 papers with an average Impact Factor of 6.3 and Hirsch-index of 28. He was elected as Board member of the Dutch Society of Pharmacology in 2015.

Department of Pharmacology & Toxicology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

2023
- Manukjan, N., Chau, S., Caiment, F., van Herwijnen, M., Smeets, H. J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Wnt7a Decreases Brain Endothelial Barrier Function Via β-Catenin Activation. Molecular Neurobiology. Advance online publication. https://doi.org/10.1007/s12035-023-03872-0
- Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5
2022
- Pinckaers, N., Blankesteijn, M., Opperhuizen, A., Van Schooten, F. J., & Vrolijk, M. (2022). In vitro pharmacological characterization of phenethylamine and alkylamine analogues found in nutritional supplements at human adrenergic and trace amine-associated receptors. Toxicology Letters, 368, S280-S280. https://doi.org/10.1016/j.toxlet.2022.07.739
2021
- Gouweleeuw, L., Wajant, H., Maier, O., Eisel, U. L. M., Blankesteijn, W. M., & Schoemaker, R. G. (2021). Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro)inflammation and behavior after myocardial infarction in male mice. Brain Behavior and Immunity, 93, 156-171. https://doi.org/10.1016/j.bbi.2021.01.001
- Daskalopoulos, E. P., & Blankesteijn, W. M. (2021). Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review. Cells, 10(2), Article 207. https://doi.org/10.3390/cells10020207
2020
- Reinhold, S., Blankesteijn, W. M., & Foulquier, S. (2020). The Interplay of WNT and PPARγ Signaling in Vascular Calcification. Cells, 9(12), Article 2658. https://doi.org/10.3390/cells9122658
- Kerkhofs, D., van Hagen, B. T., Milanova, I. V., Schell, K. J., van Essen, H., Wijnands, E., Goossens, P., Blankesteijn, W. M., Unger, T., Prickaerts, J., Biessen, E. A., van Oostenbrugge, R. J., & Foulquier, S. (2020). Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension. Theranostics, 10(21), 9512-9527. https://doi.org/10.7150/thno.44394
- Manukjan, N., Ahmed, Z., Fulton, D., Blankesteijn, W. M., & Foulquier, S. (2020). A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions: Potential Relevance to Cerebral Small Vessel Disease. Cells, 9(6), Article 1545. https://doi.org/10.3390/cells9061545
- Blankesteijn, W. M. (2020). Interventions in WNT Signaling to Induce Cardiomyocyte Proliferation: Crosstalk with Other Pathways. Molecular Pharmacology, 97(2), 90-101. https://doi.org/10.1124/mol.119.118018

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Matthijs Blankesteijn

Associate professor