Miranda Schram

Professor

Dr Miranda Schram holds a MSc in Biomedical Sciences (1999) and in Epidemiology (2002). She recieved her PhD entitled 'Patophysiology of diabetic complications, arterial stiffness, endothelial dysfunction and inflammation' at VU University Medical Center in Amsterdam in 2004, and is a registered Epidemiologist B. She has worked as post-doc epidemiologist at Erasmus MC in Rotterdam, at Leiden University Medical Center and as senior investigator at the National Institute for Public Health and the Environment in Bilthoven. From 2008 onwards, she has been working at Maastricht UMC+ as senior investigator at The Maastricht Study.

Miranda Schram is one of the founders of The Maastricht Study, a novel population-based cohort study on type 2 diabetes and its complications. Her scientific work focusses on the etiology and epidemiology of cognitive decline and depression in type 2 diabetes with a specific interest in the role of early vascular dysfunction. A second research line focusses on psychosocial aspects of diabetes, to understand how social networks, but also ethnicity and diabetes distress can affect diabetes treatment and the development of complications. Miranda is board member of The Maastricht Study, coordinator of the Dutch Diabetes Pearlstring Initiative, active member of the PSAD study group of the EASD and involved in the Netherlands Consortium of Demetia Cohorts.

Department of Internal Medicine
Randwycksingel 35, 6229 EG Maastricht
T: +31(0)6 122 64 289

  • 2026
    • Wang, X. J., Voortman, T., Bos, D., Kavousi, M., Ghanbari, M., Conrad, N., Schram, M. T., & Steur, M. (2026). Association between healthy plant-based diet-lifestyle (hPDI-Lifestyle) score and incidence of coronary heart disease, and effect modification by genetic predisposition: a prospective analysis in a population-based cohort. The Lancet Regional Health – Europe, 64, Article 101619. https://doi.org/10.1016/j.lanepe.2026.101619
    • Okoro, C., Zhou, T. L., van der Kallen, C. J. H., Koster, A., Sutedja, N. A., Berendschot, T. T. J. M., de Galan, B. E., Eussen, S. J. P. M., Schram, M. T., & Kroon, A. A. (2026). Association of type 2 diabetes according to the number of cardiovascular risk factors within the recommended range with neuropathy - The Maastricht Study. Diabetes Research and Clinical Practice, 235, Article 113212. https://doi.org/10.1016/j.diabres.2026.113212
    • Chong, M. Y., Henson, J., Bours, M. J. L., Bosma, H., de Galan, B. E., van der Kallen, C. J. H., Meertens, R. M., Savelberg, H. H. C. M., Schram, M. T., Weijenberg, M. P., Yates, T., Koster, A., & Eussen, S. J. P. M. (2026). Physical activity and meal timing alignment with chronotype and their associations with glucose metabolism: The Maastricht Study. Diabetes Obesity & Metabolism, 28(4), 3295-3304. https://doi.org/10.1111/dom.70526
    • Schaarup, J. R., Bjerg, L., Hansen, C. S., Andersen, S. T., van Greevenbroek, M. M. J., Schram, M. T., De Galan, B. E., Stehouwer, C., & Witte, D. R. (2026). Cardiovascular autonomic dysfunction is linked with arterial stiffness across glucose metabolism: the Maastricht study. BMJ Open Diabetes Research & Care, 14(2), Article e004995. https://doi.org/10.1136/bmjdrc-2025-004995
    • Wang, K., Kroon, A. A., De Galan, B. E., Berendschot, T. T. J. M., Schram, M. T., Houben, A. J. H. M., & van Greevenbroek, M. M. J. (2026). Associations of blood pressure with retinal arteriolar narrowing and urinary albumin excretion are modified by prediabetes: the Maastricht study. Journal of Hypertension, 44(3), 461-469. https://doi.org/10.1097/HJH.0000000000004225
    • van Baal, T. L., Köhler, S., Koster, A., Meertens, R. M., Bosma, H., Schram, M. T., Jansen, J. F. A., Simons, S. O., de Galan, B. E., Eussen, S. J. P. M., Janssen, N., & Deckers, K. (2026). The association between sleep parameters, cognitive functioning, and markers of brain morphology: The Maastricht Study. Sleep, 49(3), Article zsaf218. https://doi.org/10.1093/sleep/zsaf218
    • Drenthen, G. S., Backes, W. H., Kohler, S., Deckers, K., Schram, M. T., Eussen, S. J. P. M., Jansen, W. J., & Jansen, J. F. A. (2026). The role of modifiable risk factors on the cerebral myelin content and cognition: findings from The Maastricht Study. Geroscience. Advance online publication. https://doi.org/10.1007/s11357-026-02206-x
    • Dimitropoulou, N. M., Beran, M., Eussen, S. J. P. M., Dingena, C. F., Dagnelie, P. C., Van Der Kallen, C. J. H., Koster, A., Van Greevenbroek, M. M. J., Brouwers, M. C. G. J., Schram, M. T., & de Galan, B. E. (2026). Liver fat content is not elevated in people with type 1 diabetes: the Maastricht Study. Diabetologia, 69(2), 364-373. https://doi.org/10.1007/s00125-025-06597-y
  • 2025
    • Soeterboek, J., Deckers, K., Backes, W. H., Jansen, J. F. A., Schram, M. T., Bosma, H., Lakerveld, J., & Kohler, S. (2025). A cross-sectional study on the association between environmental residential noise exposure with cognitive functioning and structural markers of brain damage-The Maastricht study. Environment International, 206, Article 109932. https://doi.org/10.1016/j.envint.2025.109932
    • Okoro, C., Zhou, T. L., van der Kallen, C. J. H., Kohler, S., Schram, M. T., & Kroon, A. A. (2025). Lower heart rate variability is associated with worse memory function: The Maastricht Study. Journal of Alzheimer's Disease, 108(4), 1738-1748. https://doi.org/10.1177/13872877251389985