Otto Bekers


Prof. Otto Bekers studied Pharmacy at the University of Leiden and graduated in 1987 with honour. He recieved his PhD degree in 1991 at the Utrecht University, title of his dissertation was 'Inclusion comlexation of cyclodextrins with some cytostatic drugs'. After this he specialised in Clinical Chemistry at the Leyenburg Hospital (now Haga Hospital) in The Hague.

Since 1997 he is working as a Clinical Chemist at the Maastricht UMC+. First as head of the unit General Clinical Chemistry and from 2014 he is professor in Clinical Chemistry and head of the Central Diagnostic Laboratory (CDL).

He is heading the cardiac marker research at the CDL and also focussed on personalised medice.

Central Diagnostic Laboratory
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
Room number: 5.E2.004
T: +31 (0)43 387 646 94

  • 2024
    • Drent, M., Wijnen, P., Bekers, O., & Bast, A. (2024). Is a Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) Polymorphism a Risk Factor for Nephrolithiasis in Sarcoidosis?International Journal of Molecular Sciences, 25(8), Article 4448.
    • Drent, M., Wijnen, P. A., Jessurun, N. T., Harmsze, A. M., Bekers, O., & Bast, A. (2024). Drug-Gene Risk Stratification in Patients with Suspected Drug-Induced Interstitial Lung Disease. Drug Safety, 47(4), 355-363.
    • van Doorn, W. P. T. M., Helmich, F., van Dam, P. M. E. L., Jacobs, L. H. J., Stassen, P. M., Bekers, O., & Meex, S. J. R. (2024). Explainable Machine Learning Models for Rapid Risk Stratification in the Emergency Department: A Multicenter Study. Journal of Applied Laboratory Medicine, 9(2), 212-222. Article jfad094.
  • 2023
    • Denessen, E. J. S., Vroemen, W. H. M., Litjens, E. J. R., Henskens, Y. M. C., van der Sande, F. M., Bekers, O., de Boer, D., & Mingels, A. M. A. (2023). Cardiac Troponin T Degradation in End-Stage Renal Disease Patients Appears to Occur in Vivo. Journal of Applied Laboratory Medicine, 8(5), 1000-1002.
    • Denessen, E. J. S., Nass, S. I. J., Bekers, O., Vroemen, W. H. M., & Mingels, A. M. A. (2023). Circulating forms of cardiac troponin: a review with implications for clinical practice. Journal of Laboratory and Precision Medicine, 8(1), Article A3.
    • Heuts, S., Gollmann-Tepeköylü, C., Denessen, E. J. S., Olsthoorn, J. R., Romeo, J. L. R., Maessen, J. G., van 't Hof, A. W. J., Bekers, O., Hammarsten, O., Pölzl, L., Holfeld, J., Bonaros, N., van der Horst, I. C. C., Davidson, S. M., Thielmann, M., & Mingels, A. M. A. (2023). Cardiac troponin release following coronary artery bypass grafting: mechanisms and clinical implications. European Heart Journal, 44(2), 100-112.
  • 2022
    • Denessen, E. J., Heuts, S., Daemen, J. H., van Doorn, W. P., Vroemen, W. H., Sels, J.-W., Segers, P., Van't Hof, A. W., Maessen, J. G., Bekers, O., Van Der Horst, I. C., & Mingels, A. M. (2022). High-Sensitivity Cardiac Troponin I and T Kinetics Differ following Coronary Bypass Surgery: A Systematic Review and Meta-Analysis. Clinical Chemistry, 68(12), 1564-1575. Article hvac152.
    • Mezger, S. T. P., Mingels, A. M. A., Soulié, M., Peutz-Kootstra, C. J., Bekers, O., Mulder, P., Heeren, R. M. A., & Cillero-Pastor, B. (2022). Protein Alterations in Cardiac Ischemia/Reperfusion Revealed by Spatial-Omics. International journal of molecular sciences, 23(22), Article 13847.
    • Drent, M., Jessurun, N. T., Wijnen, P. A., Bekers, O., & Bast, A. (2022). Drug-induced comorbidities in patients with sarcoidosis. Current Opinion in Pulmonary Medicine, 28(5), 468-477.
    • Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043.