Otto Bekers


Prof. Otto Bekers studied Pharmacy at the University of Leiden and graduated in 1987 with honour. He recieved his PhD degree in 1991 at the Utrecht University, title of his dissertation was 'Inclusion comlexation of cyclodextrins with some cytostatic drugs'. After this he specialised in Clinical Chemistry at the Leyenburg Hospital (now Haga Hospital) in The Hague.

Since 1997 he is working as a Clinical Chemist at the Maastricht UMC+. First as head of the unit General Clinical Chemistry and from 2014 he is professor in Clinical Chemistry and head of the Central Diagnostic Laboratory (CDL).

He is heading the cardiac marker research at the CDL and also focussed on personalised medice.

Central Diagnostic Laboratory
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
Room number: 5.E2.004
T: +31 (0)43 387 646 94

  • 2021
    • Jessurun, N. T., Drent, M., Wijnen, P. A., Harmsze, A. M., van Puijenbroek, E. P., Bekers, O., & Bast, A. (2021). Role of Drug-Gene Interactions and Pharmacogenetics in Simvastatin-Associated Pulmonary Toxicity. Drug Safety, 44(11), 1179-1191.
    • Olie, R. H., Hensgens, R. R. K., Wijnen, P. A. H. M., Veenstra, L. F., de Greef, B. T. A., Vries, M. J. A., van der Meijden, P. E. J., ten Berg, J. M., ten Cate, H., Bekers, O., & Henskens, Y. M. C. (2021). Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients. Journal of Clinical Medicine, 10(17), [3992].
    • van Doorn, W. P. T. M., Foreman, Y. D., Schaper, N. C., Savelberg, H. H. C. M., Koster, A., van der Kallen, C. J. H., Wesselius, A., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., de Galan, B. E., Bekers, O., Stehouwer, C. D. A., Meex, S. J. R., & Brouwers, M. C. G. J. (2021). Machine learning-based glucose prediction with use of continuous glucose and physical activity monitoring data: The Maastricht Study. PLOS ONE, 16(6), [0253125].
    • Mezger, S. T. P., Mingels, A. M. A., Bekers, O., Heeren, R. M. A., & Cillero-Pastor, B. (2021). Mass Spectrometry Spatial-Omics on a Single Conductive Slide. Analytical Chemistry, 93(4), 2527-2533.
    • van Doorn, W. P. T. M., Stassen, P. M., Borggreve, H. F., Schalkwijk, M. J., Stoffers, J., Bekers, O., & Meex, S. J. R. (2021). A comparison of machine learning models versus clinical evaluation for mortality prediction in patients with sepsis. PLOS ONE, 16(1), [0245157].
    • de Boer, D., Streng, A. S., van Doorn, W. P. T. M., Vroemen, W. H. M., Bekers, O., Wodzig, W. K. W. H., & Mingels, A. M. A. (2021). Cardiac Troponin T: The Impact of Posttranslational Modifications on Analytical Immunoreactivity in Blood up to the Excretion in Urine. Advances in Experimental Medicine and Biology, 1306, 41-59.
  • 2020
    • Kimenai, D. M., Lindahl, B., Jernberg, T., Bekers, O., Meex, S. J. R., & Eggers, K. M. (2020). Sex-specific effects of implementing a high-sensitivity troponin I assay in patients with suspected acute coronary syndrome: results from SWEDEHEART registry. Scientific Reports, 10(1), [15227].
    • Cheung, C. Y., Chan, K. M., Wong, Y. T., Chak, W. L., Bekers, O., & van Hooff, J. P. (2020). Influence of CYP3A5 Genetic Polymorphism on Long-Term Renal Function in Chinese Kidney Transplant Recipients Using Limited Sampling Strategy and Abbreviated Area Under the Curve for Tacrolimus Monitoring. Progress in Transplantation, 30(3), 249-253. [1526924820933823].
    • Martens, R. J. H., Henry, R. M. A., Bekers, O., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Greevenbroek, M., Kroon, A. A., Stehouwer, C. D. A., Wesselius, A., Meex, S. J. R., & Kooman, J. P. (2020). Associations of 24-Hour Urinary Sodium and Potassium Excretion with Cardiac Biomarkers: The Maastricht Study. Journal of Nutrition, 150(6), 1413-1424.
    • Jessurun, N. T., Wijnen, P. A., Bast, A., van Puijenbroek, E. P., Bekers, O., & Drent, M. (2020). Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers. International journal of molecular sciences, 21(8), [2770].