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Catheter treatment is not only effective, but also cost-effective for ischemic stroke

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

29 September 2026

With ischemic stroke, every minute counts. However, many patients do not seek hospital care until it is too late, for example, because symptoms are not immediately recognized or because people wake up with signs of neurological deficits. As a result, a group of patients is no longer eligible for catheter treatment. 

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Platelets: more than a band-aid

Platelets: more than a band-aid

23 September 2026

Some processes in our body might seem obvious to us. If you cut your finger, the bleeding will stop shortly and form a scab. Behind that seemingly simple process hides a sophisticated system of platelets and clotting factors. By now, we know that platelets do much more than halt bleeding: they function as information carriers and regulators of disease processes. 

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Carim Maastricht
Carim Maastricht

Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Robert-van-oostenbrugge

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

 

  • 2026
    • Li, X., Roozenbeek, B., van Walsum, T., Bos, D., van der Worp, H. B., Emmer, B. J., Majoie, C. B. L., van Oostenbrugge, R. J., Dippel, D. W. J., Lingsma, H. F., & ICAI Stroke Lab (2026). Validation and simplification of the MR PREDICTS @24H model for outcome prediction after endovascular thrombectomy for acute ischemic stroke. International journal of stroke, 21(8), 1119-1129. https://doi.org/10.1177/17474930261430342
    • Xu, Y.-Y., Chappell, F. M., Valdes Hernandez, M., Arteaga Reyes, C., Clancy, U., Jaime Garcia, D., Makin, S., Stringer, M., Thrippleton, M., Wiseman, S., Cheng, Y., Liu, D. X., Brown, R., Doubal, F., Deary, I. J., Cox, S., Kerkhofs, D., Staals, J., Backes, W., ... Wardlaw, J. M. (2026). Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI. Stroke, 57(9), 2801-2812. https://doi.org/10.1161/STROKEAHA.125.055101
    • van der Taelen, L., Lambrichts, S. M. P., Temmerman, L., El Ajjouri, R., Gijbels, M. J., Bitsch, N., Scheijen, J., van de Waarenburg, M., Kutmon, M., Unger, T., Staals, J., Schalkwijk, C. G., Briones, A. M., van Oostenbrugge, R. J., & Foulquier, S. (2026). Longitudinal Profiling Reveals Divergent Kidney and Brain Immune Responses during Metabolic Syndrome. Aging and Disease. Advance online publication. https://doi.org/10.14336/AD.2026.0557
    • Pomp, A. C., Rosbergen, M. T., de Maat, M. P. M., de Vries, P. S., Ikram, M. A., Daemen, M. J. A. P., Hoefer, I. E., Niessen, W. J., de Bresser, J., Bron, E. E., Teunissen, C. E., Biessels, G. J., van Oostenbrugge, R. J., Wolters, F. J., & Heart-Brain Connection Consortium (2026). ADAMTS13 and von Willebrand Factor in relation to vascular cognitive impairment and cerebral small vessel disease: the heart-brain connection study. Journal of Thrombosis and Haemostasis, 24(8), 3041-3050. https://doi.org/10.1016/j.jtha.2026.04.022
    • Simon, S. R., Knapen, R. R. M. M., Truijman, M. T. B., van Oostenbrugge, R. J., Wagemans, B. A. J. M., van Zwam, W. H., & van der Leij, C. (2026). Timing of acute carotid artery stenting for tandem lesions in patients with acute ischemic stroke: A Maastricht Stroke Quality Registry (MaSQ-Registry) study. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 32(4), 1365-1372. Article 15910199241245166. https://doi.org/10.1177/15910199241245166
    • Lambrichts, S. M. P., van der Taelen, L., Pastor, I., Leenders, P., Bitsch, N., Majcher, D., Hermes, D., Simmonds, S. J., van Herwijnen, M., Kamps, R., Weltjens, E., Jessen, P. J. J., Steinbusch, H. P., Arentz, F., Wiesmann, M., Kiliaan, A. J., Caiment, F., Kutmon, M., Jones, E. A., ... Foulquier, S. (2026). Downregulation of Trpv4 and Klf2 in brain microvessels is associated with the progression of neurovascular dysfunction and cognitive impairment in a model of heart failure with preserved ejection fraction. Journal of Cerebral Blood Flow and Metabolism. Advance online publication. https://doi.org/10.1177/0271678X261462714
    • Pinckaers, F. M. E., Grutters, J. P. C., Evers, S. M. A. A., Lingsma, H. F., Boogaarts, H. D., Dippel, D. W. J., Postma, A. A., van der Lugt, A., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., & Gabrio, A. (2026). Mapping the mRS Into the EQ-5D-5L in Patients With Ischemic Stroke. Stroke, 57(6). https://doi.org/10.1161/STROKEAHA.126.055741
    • Robbe, M. M. Q., Knapen, R. E. M. M., van der Vleuten, J. R., Samuels, N., van der Lugt, A., van Doormaal, P. J., Majoie, C. B., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., Postma, A. A., de Ridder, I. R., & MRCLEAN Registry Investigators (2026). Predictors of spontaneous and early recanalization in stroke patients eligible for endovascular treatment. Journal of Stroke & Cerebrovascular Diseases, 35(6), Article 108641. https://doi.org/10.1016/j.jstrokecerebrovasdis.2026.108641
    • Reitsma, F. J., Verburgt, E., Schellekens, M. M. I., Hilkens, N. A., Verhoeven, J. I., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., van Tuijl, J. H., de Laat, K. F., van Norden, A., Vermeer, S. E., van Zagten, M. S. G., Wermer, M. J. H., Nederkoorn, P. J., ... Rouhl, R. P. W. (2026). Poststroke epilepsy is associated with vascular cognitive disorder in young stroke patients: The ODYSSEY study. Epilepsia, 67(6), 2855-2863. https://doi.org/10.1002/epi.70200
    • Nies, K. P. H., Ramaekers, B., Bierens, J., Auer, D. P., Schindler, A., Saam, T., Bos, D., de Jong, P. A., Nederkoorn, P. J., de Borst, G. J., van Oostenbrugge, R. J., Joore, M. A., Kooi, M. E., & Smits, L. J. M. (2026). Risk-based selection for carotid revascularisation using the IMPROVE score versus standard care in symptomatic carotid artery disease: a model-based cost-effectiveness analysis using pooled-data. BMJ Open, 16(5), Article e114391. https://doi.org/10.1136/bmjopen-2025-114391
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