Simone Eussen

Assistant Professor

Dr Simone Eussen's research focusses on the role of nutrition and underlying metabolic and molecular processes in the aetiology of common chronic diseases. She has built a strong track record on B-vitamins, related molecular one-carbon and kynurenine pathways, and chronic diseases during her PhD (Wageningen Universtiy) and post-doc (Bergen, Norway; also supported by a prestigious personal research grant from the Norwegian Research Council). She integrated this expertise to study quality of food intake at Maastricht University. Funds granted by the NWO (BBMRI) and the European JPI (Dedipac) focussed on methodological aspects of dietary assessment.

Her current work involves study of dietary quality (at nutrient and bioactive compound, food group, and dietary patterns level) in relation to chronic disease, including T2DM, CVD and mental disorders. Additionally, she expanded her focus to the emerging field of ‘chrono-nutrition’, and is member of the CIRCLE-DOME (CIRcadian CLock and timing of Eating on Diabetes, Obesity ad MEtabolism) network. Different aspects of dietary timing will be studied in relation to metabolic, cardiovascular and mental phenotypes to gain new insight in the role of chrono-nutrition in common pathologies within the framework of population based studies (for example The Maastricht Study; one of the world’s leading deep-phenotying population-based studies on T2DM and its comorbidities).

Department of Epidemiology
P. Debeyeplein 1, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: A2.018
T: +31(0)43 388 24 51

  • 2021
    • Gianfredi, V., Beran, M., Koster, A., Eussen, S. J. P. M., Odone, A., Signorelli, C., Schaper, N. C., Kohler, S., Bosma, H., Dagnelie, P. C., Stehouwer, C. D. A., Wesselius, A., Amerio, A., Brinkhues, S., Dukers-Muijrers, N., & Schram, M. T. (2021). Association between social network characteristics and prevalent and incident depression: The Maastricht Study. Journal of Affective Disorders, 293, 338-346. https://doi.org/10.1016/j.jad.2021.06.046
    • van Gennip, A. C. E., Stehouwer, C. D. A., van Boxtel, M. P. J., Verhey, F. R. J., Koster, A., Kroon, A. A., Köhler, S., van Greevenbroek, M. M. J., Wesselius, A., Eussen, S. J. P. M., Backes, W. H., Jansen, J. F., Schram, M. T., Henry, R. M. A., Singh-Manoux, A., & van Sloten, T. T. (2021). Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia. Diabetes Care. https://doi.org/10.2337/dc21-0149
    • Heger, I. S., Deckers, K., Schram, M. T., Stehouwer, C. DA., Dagnelie, P. C., van der Kallen, C. J., Koster, A., Eussen, S. J., Jansen, J. F., Verhey, F. R., van Boxtel, M. P., & Köhler, S. (2021). Associations of the Lifestyle for Brain Health Index With Structural Brain Changes and Cognition: Results From the Maastricht Study. Neurology, 97(13), E1300-E1312. https://doi.org/10.1212/WNL.0000000000012572
    • Linkens, A. M. A., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M., Henry, R. M. A., de Galan, B., Stehouwer, C. D. A., Eussen, S. J. M. P., & Schalkwijk, C. G. (2021). Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study. American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/nqab302
    • Geraets, A. F. J., Kohler, S., Jansen, J. F. A., Eussen, S. J. P. M., Stehouwer, C. D. A., Schaper, N. C., Wesselius, A., Verhey, F. R. J., & Schram, M. T. (2021). The association of markers of cerebral small vessel disease and brain atrophy with incidence and course of depressive symptoms-the maastricht study. Journal of Affective Disorders, 292, 439-447. https://doi.org/10.1016/j.jad.2021.05.096
    • Bakker, L., Ramakers, I. H. G. B., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., van der Kallen, C. J. H., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Midttun, Ø., Ueland, P. M., Verhey, F. R. J., Eussen, S. J. P. M., & Köhler, S. (2021). Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. Diabetologia, 64(11), 2445-2457. https://doi.org/10.1007/s00125-021-05521-4
    • van der Heide, F. C. T., Zhou, T. L., Henry, R. M. A., Houben, A. J. H. M., Kroon, A. A., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., Schram, M. T., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Koster, A., Savelberg, H. H. C. M., Schaper, N. C., Reesink, K. D., & Stehouwer, C. D. A. (2021). Carotid stiffness is associated with retinal microvascular dysfunction- The Maastricht Study. Microcirculation, 28(6), [e12702]. https://doi.org/10.1111/micc.12702
    • Foreman, Y. D., van Doorn, W. P. T. M., Schaper, N. C., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Henry, R. M. A., Koster, A., Eussen, S. J. P. M., Wesselius, A., Reesink, K. D., Schram, M. T., Dagnelie, P. C., Kroon, A. A., Brouwers, M. C. G. J., & Stehouwer, C. D. A. (2021). Greater daily glucose variability and lower time in range assessed with continuous glucose monitoring are associated with greater aortic stiffness: The Maastricht Study. Diabetologia, 64(8), 1880-1892. https://doi.org/10.1007/s00125-021-05474-8
    • de Ritter, R., Sep, S. J. S., van der Kallen, C. J. H., van Greevenbroek, M. M. J., de Jong, M., Vos, R. C., Bots, M. L., Reulen, J. P. H., Houben, A. J. H. M., Webers, C. A. B., Berendschot, T. T. J. M., Dagnelie, P. C., Eussen, S. J. P. M., Schram, M. T., Koster, A., Peters, S. A. E., & Stehouwer, C. D. A. (2021). Sex differences in the association of prediabetes and type 2 diabetes with microvascular complications and function: The Maastricht Study. Cardiovascular Diabetology, 20(1), 102. [102]. https://doi.org/10.1186/s12933-021-01290-x
    • Gianfredi, V., Koster, A., Odone, A., Amerio, A., Signorelli, C., Schaper, N. C., Bosma, H., Kohler, S., Dagnelie, P. C., Stehouwer, C. D. A., Schram, M. T., van Dongen, M. C. J. M., & Eussen, S. J. P. M. (2021). Associations of Dietary Patterns with Incident Depression: The Maastricht Study. Nutrients, 13(3), [1034]. https://doi.org/10.3390/nu13031034