Simone Eussen

Assistant Professor

Dr Simone Eussen's research focusses on the role of nutrition and underlying metabolic and molecular processes in the aetiology of common chronic diseases. She has built a strong track record on B-vitamins, related molecular one-carbon and kynurenine pathways, and chronic diseases during her PhD (Wageningen Universtiy) and post-doc (Bergen, Norway; also supported by a prestigious personal research grant from the Norwegian Research Council). She integrated this expertise to study quality of food intake at Maastricht University. Funds granted by the NWO (BBMRI) and the European JPI (Dedipac) focussed on methodological aspects of dietary assessment.

Her current work involves study of dietary quality (at nutrient and bioactive compound, food group, and dietary patterns level) in relation to chronic disease, including T2DM, CVD and mental disorders. Additionally, she expanded her focus to the emerging field of ‘chrono-nutrition’, and is member of the CIRCLE-DOME (CIRcadian CLock and timing of Eating on Diabetes, Obesity ad MEtabolism) network. Different aspects of dietary timing will be studied in relation to metabolic, cardiovascular and mental phenotypes to gain new insight in the role of chrono-nutrition in common pathologies within the framework of population based studies (for example The Maastricht Study; one of the world’s leading deep-phenotying population-based studies on T2DM and its comorbidities).

Department of Epidemiology
P. Debeyeplein 1, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: A2.018
T: +31(0)43 388 24 51

  • 2026
    • Valente, M. J., Cao, B., Holthuijsen, D. D. B., Bours, M. J. L., Eussen, S. J. P. M., Weijenberg, M. P., & Rijnhart, J. J. M. (2026). Omission of main effects from regression models with a ratio variable as the focal exposure can result in bias and inflated type I error rates. Journal of Clinical Epidemiology, 190, Article 112092. https://doi.org/10.1016/j.jclinepi.2025.112092
    • Dimitropoulou, N. M., Beran, M., Eussen, S. J. P. M., Dingena, C. F., Dagnelie, P. C., Van Der Kallen, C. J. H., Koster, A., Van Greevenbroek, M. M. J., Brouwers, M. C. G. J., Schram, M. T., & de Galan, B. E. (2026). Liver fat content is not elevated in people with type 1 diabetes: the Maastricht Study. Diabetologia, 69(2), 364-373. https://doi.org/10.1007/s00125-025-06597-y
  • 2025
    • van Oeteren, M. A. J., De Groot, D. M., Buziau, A. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Kroon, A. A., Eussen, S. J. P. M., Dagnelie, P. C., Van Greevenbroek, M. M. J., Houben, A. J. H. M., Meex, S. J. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). The effects of dietary fructose on blood pressure are modified by the food matrix. Clinical Nutrition, 55, 134-140. https://doi.org/10.1016/j.clnu.2025.10.017
    • Pulsford, R. M., Bakker, E. A., Ahmadi, M., Blodgett, J. M., Bosma, H., Brocklebank, L., Eussen, S. J. P. M., Hamer, M., Lear, R., Metcalf, B., Savelberg, H., Stamatakis, E., & Koster, A. (2025). Not all steps are equal: independent prospective associations of stepping volume and patterns with incident type 2 diabetes mellitus in the Maastricht study. International Journal of Behavioral Nutrition and Physical Activity, 22(1), Article 145. https://doi.org/10.1186/s12966-025-01839-z
    • Mayen, A.-L., Maasen, K., Hana, C., Knaze, V., Scheijen, J., Eussen, S. J. P. M., Vangrieken, P., Debras, C., Blanco, J., Dahm, C. C., Aleksandrova, K., Schulze, M. B., Dansero, L., Masala, G., Panico, S., Sieri, S., Guevara, M., Moreno Iribas, C., Petrova, D., ... Jenab, M. (2025). Higher intakes of dietary dicarbonyl compounds are associated with lower risk of cardiovascular disease. European Journal of Preventive Cardiology, 32(16), 1588-1600. Article zwaf060. https://doi.org/10.1093/eurjpc/zwaf060
    • Chokor, F. A. Z., Eussen, S. J. P. M., Crone, M., Abdulmalik, M., Ayoub, J., Zgheib, P., Chatila, A., Nasreddine, L., & Naja, F. (2025). Adherence to the Lebanese National Dietary and Lifestyle Guidelines for Pregnancy and Its Association With Postpartum Weight Retention. Maternal and Child Nutrition, 21(4), Article e70070. https://doi.org/10.1111/mcn.70070
    • Dimitropoulou, N. M., Eussen, S. J. P. M., Schalkwijk, C. G., & de Galan, B. E. (2025). Glucose variability measured by continuous glucose monitoring is associated with skin autofluorescence: the Maastricht Study. Diabetologia, 68(9), 1937-1946. https://doi.org/10.1007/s00125-025-06469-5
    • Steens, I. L. M., Schram, M. T., Houben, A. J. H. M., Berendschot, T. T. J. M., Koster, A., Bosma, H., Eussen, S. J. P. M., de Galan, B. E., & van Sloten, T. T. (2025). Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products (AGEs), and arterial stiffness. Diabetes Obesity & Metabolism, 27(9), 4847-4858. Article 16527. https://doi.org/10.1111/dom.16527
    • Rao, Y., Yu, E. Y.-W., Lin, T.-Y., Chen, Y., Qin, Y., Koster, A., Eussen, S. J. P. M., Bosma, H., Berendschot, T. T. J. M., van der Kallen, C. J. H., van Greevenbroek, M. M. J., de Galan, B. E., Zeegers, M. P., & Wesselius, A. (2025). Interaction between coffee consumption and polygenic risk score in relation to diabetes: insights from the Maastricht study. European Journal of Nutrition, 64(6), Article 263. https://doi.org/10.1007/s00394-025-03782-y
    • van Baal, T. L., Köhler, S., Koster, A., Meertens, R. M., Bosma, H., Schram, M. T., Jansen, J. F. A., Simons, S. O., de Galan, B. E., Eussen, S. J. P. M., Janssen, N., & Deckers, K. (2025). The association between sleep parameters, cognitive functioning, and markers of brain morphology: The Maastricht Study. Sleep, Article zsaf218. https://doi.org/10.1093/sleep/zsaf218