Stephane Heymans

Professor

Stephane Heymans is Professor of Cardiomyopathies and Head of the Centre for Heart Failure Research, Department of Cardiology, Maastricht University. He obtained his Medical Degree from the KU Leuven (Belgium) in 1995 and went on to get a PhD in Medical Sciences in 2000, studying the role of proteinases in acute myocardial infarction. In 2003, he joined the Department of Cardiology of Maastricht UMC+ as an academic medical specialist and in 2006 he took over the Multidisciplinary Cardiomyopathy Program (Genetics, Immunology, Microbiology and Pathology departments).

In 2008, he established his independent research laboratory at Cardiovascular Research Institute Maastricht. His research interests focus on the molecular mechanisms of heart failure, looking at the interplay between inflammatory cells, fibroblasts and cardiomyocytes. Particular focus is on the role of non-structural matrix proteins, matrix turnover and non-coding RNAs.

Furthermore, he is Professor of 'Inflammation and Matrix Biology in Cardiomyopathies' at the University of Leuven and he is a board member of the ESC Heart Failure Association, ESC Working Group of Myocardial Function, ESC Heart Failure Association Committee on Diastolic Heart Failure and ESC Heart Failure Association Committee on Translational Research.

Website www.hfresearch.eu

Department of Cardiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: G3.230
T: +31(0)43 388 43 04

  • 2026
    • Verdonschot, J. A. J., Van Spaendonck-Zwarts, K. Y., Hellebrekers, D. M. E., Asselbergs, F. W., Behr, E. R., Charron, P., Dawson, D., Garcia-Pavia, P., Haugaa, K. H., Jurcut, R., Kuchynka, P., Lopes, L. R., Mazzanti, A., Metra, M., Monserrat, L., Kaski, J. P., Pantazis, A., Prasad, S. K., Rosano, G., ... Van Tintelen, J. P. (2026). Genetic counselling implementation in dilated cardiomyopathy: A clinical consensus statement of the Heart Failure Association of the ESC, the ESC Working Group on Myocardial and Pericardial Diseases, and the ESC Council on Cardiovascular Genomics. European Heart Journal, 47(24), 3040-3051. https://doi.org/10.1093/eurheartj/ehag159
    • Heymans, S. (2026). The dual face of lamin A/C cardiomyopathy: risk prediction of heart failure and arrhythmias. European Heart Journal, 47(24), 3149-3151. https://doi.org/10.1093/eurheartj/ehag215
    • Bianchi, L., Afonso, L., Chendey, T., Modumudi, S., Minghini, A., Verdonschot, J. A. J., & Heymans, S. R. B. (2026). Efficacy and safety of sodium-glucose cotransporter inhibitors in hypertrophic cardiomyopathy: a systematic review. IJC Heart and Vasculature, 64, Article 101906. https://doi.org/10.1016/j.ijcha.2026.101906
    • Skouri, H., Abdin, A., Mullens, W., Bucciarelli Ducci, C., Starling, R. C., Van der Meer, P., Savarese, G., ben Gal, T., Bayes-Genis, A., Heymans, S., Klingel, K., Prasad, S. K., Farmakis, D., Chioncel, O., Ristic, A., Rosano, G., Seferovic, P., Ponikowiski, P., Metra, M., & Tschope, C. (2026). Evaluation and management of recent onset cardiomyopathy in the current era of heart failure therapeutics: a clinical consensus statement of the Heart Failure Association of the ESC. Esc heart failure, 13(3), Article xvag115. https://doi.org/10.1093/eschf/xvag115
    • Baggio, C., Cannata, A., Gasperetti, A., Ammirati, E., Gentile, P., Peretto, G., Savonitto, G., Cecere, A., Collini, V., Sikking, M., Mistrulli, R., Pagannone, E., Rossi, V. A., Schmidt, D., Compagnucci, P., Casella, M., Artico, J., Ciabatti, M., Fabris, E., ... Marco, M. (2026). Insights Into the Natural History of Recurrent Myocarditis, A Multicenter International Study (Re-Myo Study). Journal of the American Heart Association, 15(10), Article e046767. https://doi.org/10.1161/JAHA.125.046767
    • de Gonzalo-Calvo, D., García-Hidalgo, M. C., Chatterjee, S., Thum, S., Ferreira, J. P., Rossignol, P., Girerd, N., Verdonschot, J. A. J., Heymans, S., Staessen, J. A., Cleland, J. G. F., Zannad, F., Thum, T., & Bär, C. (2026). Mechanistic insights into heart failure progression and therapeutic target discovery through plasma microRNA profiling: Findings from HOMAGE. European journal of internal medicine, 147, Article 106724. https://doi.org/10.1016/j.ejim.2026.106724
    • Deissler, P. M., Rahm, A. K., Berkovitch, A., Müller, M. E., Sikking, M., Heymans, S., Langenberg, B., Moersdorf, M., Rieder, M., Nimani, S., Odening, K. E., Dichtl, W., Sabbag, A., Volders, P. G. A., & Ter Bekke, R. M. A. (2026). Temporal variability of the electromechanical window in long-QT syndrome and drug-induced QT prolongation: Value for enhanced arrhythmia-risk assessment. Heart Rhythm, 23(4), e636-e646. https://doi.org/10.1016/j.hrthm.2026.01.013
    • Ravassa, S., Girerd, N., Edelman, F., Lopez, B., Ferreira, J. P., Zurkan, D., Jose, G. S., Latasa, I., Pellicori, P., Cosmi, F., Petutschnigg, J., Heymans, S., Brunner-La Rocca, H.-P., Pieske, B., Delles, C., Clark, A. L., Diez, J., Zannad, F., Cleland, J. G. F., ... HOMAGE Trial Committees and Investigators (2026). Spironolactone and Fibrosis in Heart Failure Risk: Machine Learning Analysis of HOMAGE Trial Plasma Proteomics. MedComm, 7(3), Article e70634. https://doi.org/10.1002/mco2.70634
    • Torfs, T., Veltrop, R. J. A., Lezzoche, G., Heymans, S. R. B., Verdonschot, J. A. J., & Nabben, M. (2026). Metabolic Dysregulation in Laminopathies: Implications for Heart Failure and Cardiac Health. Current Heart Failure Reports, 23(1), Article 6. https://doi.org/10.1007/s11897-025-00735-8
    • Raafs, A. G., Verdonschot, J. A. J., Knackstedt, C., Nijveldt, R., & Heymans, S. R. B. (2026). Clinical and prognostic impact of left atrial strain in non-ischemic cardiomyopathies. International Journal of Cardiovascular Imaging, 42(2), 175-193. https://doi.org/10.1007/s10554-025-03597-2