Thomas Van Sloten

Post doc

Dr Thomas van Sloten studied Medicine at Maastricht University and Clinical Epidemiology at VU University Amsterdam, both in the Netherlands. The focus of his research is the role of primordial prevention of cardiovascular and cerebrovascular diseases and the contribution of vascular dysfunction to brain diseases (stroke, dementia, depression).

He did his PhD research under supervision of Prof. Coen Stehouwer at the Department of Internal Medicine of Maastricht UMC+, within CARIM. During his PhD project, Thomas also worked at the National Institutes of Health, Bethesda, Maryland, under supervision of Dr Launer and Dr Mitchell. Recently, he did a post-doctoral research fellowship at INSERM U970, Cardiovascular Research Center, Paris, France, under supervision of Dr Empana, Prof. Boutouyrie and Prof. Laurent.

Currently, Thomas works as a resident internal medicine and post-doctoral researcher at Maastricht UMC+. In 2018, Thomas was awarded a Veni grant by the Dutch Research Council NWO talent scheme and Dr. Dekker clinical scientist grant by the Dutch Heart Foundation. Using this grants, Thomas investigates the role of microvascular dysfunction in the development of depression in individuals with and without cardiovascular disease.

Department of Internal Medicine
Randwycksingel 35, 6229 EG Maastrichtl
T: +31(0)621 214 590

2021
- van der Heide, F. C. T., Steens, I. L. M., Geraets, A. F. J., Foreman, Y. D., Henry, R. M. A., Kroon, A. A., van der Kallen, C. J. H., van Sloten, T. T., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Koster, A., Schaper, N. C., Schram, M. T., ... Stehouwer, C. D. A. (2021). Association of Retinal Nerve Fiber Layer Thickness, an Index of Neurodegeneration, With Depressive Symptoms Over Time. Jama network open, 4(11), e2134753. [2134753]. https://doi.org/10.1001/jamanetworkopen.2021.34753
- van Gennip, A. C. E., Stehouwer, C. D. A., van Boxtel, M. P. J., Verhey, F. R. J., Koster, A., Kroon, A. A., Köhler, S., van Greevenbroek, M. M. J., Wesselius, A., Eussen, S. J. P. M., Backes, W. H., Jansen, J. F., Schram, M. T., Henry, R. M. A., Singh-Manoux, A., & van Sloten, T. T. (2021). Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia. Diabetes Care. https://doi.org/10.2337/dc21-0149
- Empana, J. P., Boutouyrie, P., Lemogne, C., Jouven, X., & van Sloten, T. T. (2021). Microvascular Contribution to Late-Onset Depression: Mechanisms, Current Evidence, Association With Other Brain Diseases, and Therapeutic Perspectives. Biological Psychiatry, 90(4), 214-225. https://doi.org/10.1016/j.biopsych.2021.04.012
- Lisan, Q., van Sloten, T., Boutouyrie, P., Laurent, S., Danchin, N., Thomas, F., Guibout, C., Perier, M-C., Dagnelie, P., Henry, R. M., Schram, M. T., Heinzer, R., Marques-Vidal, P., van der Kallen, C. J., Crijns, H. J., van Greevenbroek, M., Reesink, K., Kohler, S., Sastry, M., ... Empana, J-P. (2021). Sleep Apnea is Associated With Accelerated Vascular Aging: Results From 2 European Community-Based Cohort Studies. Journal of the American Heart Association, 10(15), [021318]. https://doi.org/10.1161/JAHA.120.021318
- Amidei, C. B., Fayosse, A., Dumurgier, J., Machado-Fragua, M. D., Tabak, A. G., van Sloten, T., Kivimaki, M., Dugravot, A., Sabia, S., & Singh-Manoux, A. (2021). Association Between Age at Diabetes Onset and Subsequent Risk of Dementia. JAMA-Journal of the American Medical Association, 325(16), 1640-1649. https://doi.org/10.1001/jama.2021.4001
- Zhou, T. L., Kroon, A. A., Henry, R. M. A., Koster, A., Dagnelie, P. C., Bosma, H., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Wesselius, A., Reesink, K. D., Kohler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2021). Exercise SBP response and incident depressive symptoms: The Maastricht Study. Journal of Hypertension, 39(3), 494-502. https://doi.org/10.1097/HJH.0000000000002657
- Vergoossen, L. W. M., Jansen, J. F. A., van Sloten, T. T., Stehouwer, C. D. A., Schaper, N. C., Wesselius, A., Dagnelie, P. C., Kohler, S., van Boxtel, M. P. J., Kroon, A. A., de Jong, J. J. A., Schram, M. T., & Backes, W. H. (2021). Interplay of White Matter Hyperintensities, Cerebral Networks, and Cognitive Function in an Adult Population: Diffusion-Tensor Imaging in the Maastricht Study. Radiology, 298(2), 384-392. https://doi.org/10.1148/radiol.2021202634
2020
- Lisan, Q., van Sloten, T., Climie, R. E., Boutouyrie, P., Guibout, C., Thomas, F., Danchin, N., Jouven, X., & Empana, J-P. (2020). Sleep apnoea is associated with hearing impairment: The Paris prospective study 3. Clinical Otolaryngology, 45(5), 681-686. https://doi.org/10.1111/coa.13557
- Geraets, A. F. J., van Agtmaal, M. J. M., Stehouwer, C. D. A., Sörensen, B. M., Berendschot, T. T. J. M., Webers, C. A. B., Schaper, N. C., Henry, R. M. A., van der Kallen, C. J. H., Eussen, S. J. P. M., Koster, A., van Sloten, T. T., Köhler, S., Schram, M. T., & Houben, A. J. H. M. (2020). Association of Markers of Microvascular Dysfunction With Prevalent and Incident Depressive Symptoms: The Maastricht Study. Hypertension, 76(2), 342-349. https://doi.org/10.1161/HYPERTENSIONAHA.120.15260
- Zhou, T. L., Rensma, S. P., van der Heide, F. C. T., Henry, R. M. A., Kroon, A. A., Houben, A. J. H. M., Jansen, J. F. A., Backes, W. H., Berendschot, T. T. J. M., Schouten, J. S. A. G., van Dongen, M. C. J. M., Eussen, S. J. P. M., Dagnelie, P. C., Webers, C. A. B., Schram, M. T., Schalkwijk, C. G., van Sloten, T. T., & Stehouwer, C. D. A. (2020). Blood pressure variability and microvascular dysfunction: the Maastricht Study. Journal of Hypertension, 38(8), 1541-1550. https://doi.org/10.1097/HJH.0000000000002444

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Thomas Van Sloten

Post doc