Thomas Van Sloten

Post doc

Dr Thomas van Sloten studied Medicine at Maastricht University and Clinical Epidemiology at VU University Amsterdam, both in the Netherlands. The focus of his research is the epidemiological study of the role of microvascular dysfunction in the development brain diseases, including stroke, dementia and depression.

He did his PhD research under supervision of Prof. Coen Stehouwer at the Department of Internal Medicine of Maastricht UMC+, within CARIM. Thomas also worked at the National Institutes of Health (USA) and at INSERM U970, Paris Cardiovascular Research Center (France).

Currently, Thomas works as a resident internal medicine and post-doctoral research fellow with a Tenure-track position at Maastricht UMC+. Thomas has been awarded with various grants, including a Veni grant (Dutch Research Council NWO talent scheme), a Dekker clinical scientist grant (Dutch Heart Foundation) and a Diabetes Fonds Junior Fellowship (Dutch Diabetes Research Foundation).

Department of Internal Medicine
Randwycksingel 35, 6229 EG Maastrichtl
T: +31(0)621 214 590

2024
- Beran, M., van Gennip, A. C. E., Stehouwer, C. D. A., Jansen, J. F. A., Gupta, M. D., Houben, A. J. H. M., Berendschot, T. T. J. M., Webers, C. A. B., Wesselius, A., Schalkwijk, C. G., Backes, W. H., de Jong, J. J. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Köhler, S., Vonk, J. M. J., Geerlings, M. I., Schram, M. T., & van Sloten, T. T. (2024). Microvascular Dysfunction and Whole-Brain White Matter Connectivity: The Maastricht Study. Journal of the American Heart Association, 13(3), Article e9112. https://doi.org/10.1161/JAHA.123.031573
- van der Heide, F. C. T., Steens, I. L. M., Limmen, B., Mokhtar, S., van Boxtel, M. P. J., Schram, M. T., Köhler, S., Kroon, A. A., van der Kallen, C. J. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., Koster, A., van Sloten, T. T., Jansen, J. F. A., Backes, W. H., & Stehouwer, C. D. A. (2024). Thinner inner retinal layers are associated with lower cognitive performance, lower brain volume, and altered white matter network structure-The Maastricht Study. Alzheimer's & Dementia, 20(1), 316-329. https://doi.org/10.1002/alz.13442
2023
- Geraets, A. F. J., Köhler, S., Vergoossen, L. W., Backes, W. H., Stehouwer, C. D. A., Verhey, F. R., Jansen, J. F., van Sloten, T. T., & Schram, M. T. (2023). The association of white matter connectivity with prevalence, incidence and course of depressive symptoms: The Maastricht Study. Psychological Medicine, 53(12), 5558-5568. Article 0033291722002768. https://doi.org/10.1017/S0033291722002768
- van Sloten, T. T., Climie, R. E. D., Deraz, O., Périer, M.-C., Valentin, E., Fayosse, A., Sabia, S., Weiderpass, E., Jouven, X., Goldberg, M., Zins, M., Touvier, M., Deschasaux-Tanguy, M., Fezeu, L., Hercberg, S., Singh-Manoux, A., & Empana, J.-P. (2023). Is the number of ideal cardiovascular health metrics in midlife associated with lower risk of cancer? Evidence from 3 European prospective cohorts. CMAJ Open, 11(4), E774-E781. https://doi.org/10.9778/cmajo.20220175
- van Gennip, A. C. E., Schram, M., Kohler, S., Kroon, A. A., Koster, A., Eussen, S. J. P. M., de Galan, B. E., van Sloten, T. T., & Stehouwer, C. D. A. (2023). Association of type 2 diabetes according to the number of risk factors within the recommended range with incidence of major depression and clinically relevant depressive symptoms: a prospective analysis. The Lancet Healthy Longevity, 4(2), e63-e71. https://doi.org/10.1016/S2666-7568(22)00291-4
2022
- Empana, J.-P., Lerner, I., Perier, M.-C., Guibout, C., Jabre, P., Bailly, K., Andrieu, M., Climie, R., van Sloten, T., Vedie, B., Geromin, D., Marijon, E., Thomas, F., Danchin, N., Boutouyrie, P., & Jouven, X. (2022). Ultrasensitive Troponin I and Incident Cardiovascular Disease. Arteriosclerosis Thrombosis and Vascular Biology, 42(12), 1471-1481. https://doi.org/10.1161/atvbaha.122.317961
- van der Heide, F. C. T., van Sloten, T. T., Willekens, N., & Stehouwer, C. D. A. (2022). Neurovascular coupling unit dysfunction and dementia: Retinal measurements as tools to move towards population-based evidence. Frontiers in Endocrinology, 13, Article 1014287. https://doi.org/10.3389/fendo.2022.1014287
- Machado-Fragua, M. D., Fayosse, A., Yerramalla, M. S., van Sloten, T. T., Tabak, A. G., Kivimaki, M., Sabia, S., & Singh-Manoux, A. (2022). Association of Metabolic Syndrome With Incident Dementia: Role of Number and Age at Measurement of Components in a 28-Year Follow-up of the Whitehall II Cohort Study. Diabetes Care, 45(9), 2127-2135. https://doi.org/10.2337/dc22-0206
- Rebelos, E., Daniele, G., Campi, B., Saba, A., Koskensalo, K., Ihalainen, J., Saukko, E., Nuutila, P., Backes, W. H., Jansen, J. F. A., Dagnelie, P. C., Köhler, S., de Galan, B. E., van Sloten, T. T., Stehouwer, C. D. A., & Ferrannini, E. (2022). Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans. Scientific Reports, 12(1), Article 11530. https://doi.org/10.1038/s41598-022-15670-0
- van Sloten, T. T., Souverein, P. C., Stehouwer, C. DA., & Driessen, J. H. (2022). Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers and risk of depression among older people with hypertension. Journal of Psychopharmacology, 36(5), 594-603. Article 02698811221082470. https://doi.org/10.1177/02698811221082470

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Thomas Van Sloten

Post doc