Vanessa van Empel

Associate professor

Dr Vanessa van Empel studied Medicine at the University of Maastricht. During her studies, she started her PhD on the topic heart failure. She obtained her PhD from the University of Utrecht in 2007. Subsequently she started her training as a cardiologist at the Maastricht University Medical Centre. After finishing her cardiology training in 2011, Vanessa was rewarded the ICIN fellowship, which enabled her to do a post-doctoral fellowship at the Alfred Hospital in Melbourne, Australia, where she gained more expertise in the field of heart failure with preserved ejection fraction (HFpEF). She now is a staff member at the Maastricht UMC+ with an expertise in heart failure, and heart failure with preserved ejection fraction specifically.

Her clinical work and research has been dedicated to HFpEF. She initiated the HFpEF clinic in Maastricht, which started in 2015, and is responsible for the Maastricht HFpEF cohort. She obtained a grant 'Vrouwelijk Hartfalen' from the Health Foundation Limburg together with Prof. Blanche Schroen, is co-PI on the CVON project Early detection of HFpEF and is project leader of the CVON SHE-PREDICT-HF, which studies sex differences in HFpEF. These projects allow her to continue her research on HFpEF with special focus on cardiovascular imaging, biomarkers and microvascular dysfunction.

Department of Cardiology
P. Debeyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: Maastricht UMC+ level 3
T: +31(0)43 387 70 95

  • 2024
    • Carland, C., Zhao, L., Salman, O., Cohen, J. B., Zamani, P., Xiao, Q., Dongre, A., Wang, Z., Ebert, C., Greenawalt, D., van Empel, V., Richards, A. M., Doughty, R. N., Rietzschel, E., Javaheri, A., Wang, Y., Schafer, P. H., Hersey, S., Carayannopoulos, L. N., ... Chirinos, J. A. (2024). Urinary Proteomics and Outcomes in Heart Failure With Preserved Ejection Fraction. Journal of the American Heart Association, (9), Article 033410. Advance online publication. https://doi.org/10.1161/JAHA.123.033410
    • Verdonschot, J. A. J., Hellebrekers, D. M. E. I., van Empel, V. P. M., Heijligers, M., de Munnik, S., Coonen, E., Dreesen, J. C. M. F., van den Wijngaard, A., Brunner, H. G., Zamani Esteki, M., Heymans, S. R. B., de Die-Smulders, C. E. M., & Paulussen, A. D. C. (2024). Clinical Guideline for Preimplantation Genetic Testing in Inherited Cardiac Diseases. Circulation: Genomic and Precision Medicine, 17(2), Article E004416. https://doi.org/10.1161/CIRCGEN.123.004416
    • Dib, M.-J., Levin, M. G., Zhao, L., Diab, A., Wang, Z., Ebert, C., Salman, O., Azzo, J. D., Gan, S., Zamani, P., Cohen, J. B., Gill, D., Burgess, S., Zagkos, L., van Empel, V., Richards, A. M., Doughty, R., Rietzschel, E. R., Kammerhoff, K., ... Chirinos, J. A. (2024). Proteomic Associations of Adverse Outcomes in Human Heart Failure. Journal of the American Heart Association, 13(5), Article e031154. https://doi.org/10.1161/JAHA.123.031154
    • Tubben, A., Tingen, H. S. A., Prakken, N. H. J., van Empel, V. P. M., Gorter, T. M., Meems, L. M. G., Manintveld, O. C., Rienstra, M., Tieleman, R. G., Glaudemans, A. W. J. M., van Veldhuisen, D. J., Slart, R. H. J. A., Nienhuis, H. L. A., & van der Meer, P. (2024). Prevalence of wild-type transthyretin amyloidosis in a prospective heart failure cohort with preserved and mildly reduced ejection fraction: Results of the Amylo-VIP-HF study. European journal of heart failure. Advance online publication. https://doi.org/10.1002/ejhf.3186
    • Azzo, J. D., Dib, M.-J., Zagkos, L., Zhao, L., Wang, Z., Chang, C.-P., Ebert, C., Salman, O., Gan, S., Zamani, P., Cohen, J. B., van Empel, V., Richards, A. M., Javaheri, A., Mann, D. L., Rietzschel, E. R., Schafer, P. H., Seiffert, D. A., Gill, D., ... Chirinos, J. A. (2024). Proteomic Associations of NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) in Heart Failure With Preserved Ejection Fraction. Circulation-Heart Failure, 17(2), Article e011146. https://doi.org/10.1161/CIRCHEARTFAILURE.123.011146
    • Clephas, P. R. D., Malgie, J., Schaap, J., Koudstaal, S., Emans, M., Linssen, G. C. M., de Boer, G. A., van Heerebeek, L., Borleffs, C. J. W., Manintveld, O. C., van Empel, V., van Wijk, S., van den Heuvel, M., da Fonseca, C., Damman, K., van Ramshorst, J., van Kimmenade, R., van de Ven, A. R. T., Tio, R. A., ... Brugts, J. J. (2024). Guideline implementation, drug sequencing, and quality of care in heart failure: design and rationale of TITRATE-HF. Esc heart failure, 11(1), 550-559. https://doi.org/10.1002/ehf2.14604
    • Nebhwani, M., Chaibekava, K., Achten, A., Oerlemans, M. I. F. J., Michels, M., van der Meer, P., Nienhuis, H. L. A., Weerts, J., van Empel, V., Rocca, H. P. B. L., Wijk, S. S. V., van der Pol, J., & Knackstedt, C. (2024). Detection of cardiac amyloidosis on routine bone scintigraphy: an important gatekeeper role for the nuclear medicine physician. International Journal of Cardiovascular Imaging. Advance online publication. https://doi.org/10.1007/s10554-024-03085-z
    • Adamo, M., Chioncel, O., Pagnesi, M., Bayes-Genis, A., Abdelhamid, M., Anker, S. D., Antohi, E.-L., Badano, L., Ben Gal, T., Böhm, M., Delgado, V., Dreyfus, J., Faletra, F. F., Farmakis, D., Filippatos, G., Grapsa, J., Gustafsson, F., Hausleiter, J., Jaarsma, T., ... Metra, M. (2024). Epidemiology, Pathophysiology, Diagnosis and Management of Chronic Right-Sided Heart Failure and Tricuspid Regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. European journal of heart failure, 26(1), 18-33. https://doi.org/10.1002/ejhf.3106
    • Litwin, S. E., Komtebedde, J., Seidler, T., Borlaug, B. A., Winkler, S., Solomon, S. D., Eicher, J.-C., Mazimba, S., Khawash, R., Sverdlov, A. L., Hummel, S. L., Bugger, H., Boenner, F., Hoendermis, E., Cikes, M., Demers, C., Silva, G., van Empel, V., Starling, R., ... REDUCE LAP-HF investigators and research staff (2024). Obesity in Heart Failure with Preserved Ejection Fraction: Insights from the REDUCE LAP-HF II Trial. European journal of heart failure, 26(1), 177-189. https://doi.org/10.1002/ejhf.3092
  • 2023
    • Knackstedt, C., Ramaekers, B., Schummers, G., Schreckenberg, M., Faessen, J., Marx, N., Becker, M., Sanders-van Wijk, S., van Empel, V., Norra, C., Kunert, H. J., Brunner-La Rocca, H.-P., & PsychEcho study group (2023). Influence of Individual Personality Traits of the Reader on Visual Assessment of Left Ventricular Ejection Fraction: Another Reason to Abandon Visual Assessment. Journal of the American Society of Echocardiography, 36(12), 1332-1335. https://doi.org/10.1016/j.echo.2023.08.015