Werner Mess


Prof. Werner Mess received his medical degree in 1989 at the University of Düsseldorf, whereafter he was a resident in neurology in Mannheim/Heidelberg and Düsseldorf until 1994. As a certified neurologist he went to Nieuwegein (NL), where he worked as a clinical neurophysiologist for two years. In 1997, he became staff member and subsequently (2006) chairman of the Department of Clinical Neurophysiology at Maastricht University. In 2003, he received his PhD in Medicine at Maastricht University on the physical properties of microembolus detection and in 2007 became professor of clinical neurophysiology.

He has been involved in ultrasound since his first scientific activities resulting in a thesis based on CW Doppler measurements of the carotid and vertebral arteries in patients with an asymptomatic vascular disease. Since then, he has performed and participated in multiple studies on plaque morphology as well as microembolus detection. The latter led to his PhD degree and focussed on the physical aspects of the method. Currently, he focusses on long-term embolus detection, as well as the combined evaluation of functional, and anatomical properties of the carotid artery by means of ultrasound. He is an internationally recognised expert in this field and a member of the ESNCH and board member of the Neurosonology Research Group.

Department of Clinical Neurophysiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
: +31(0)43 387 52 73

  • 2021
    • Weise, D., Groiss, S. J., Klinker, F., Mess, W. H., Milnik, V., & Zeller, D. (2021). Evozierte Potenziale – Reminder und Update. Klinische Neurophysiologie, 52(03), 195-211. https://doi.org/10.1055/a-1416-3874
    • Stevens, R. R. F., Gommer, E. D., Aries, M. J. H., Ertl, M., Mess, W. H., Huberts, W., & Delhaas, T. (2021). Optic nerve sheath diameter assessment by neurosonology: A review of methodologic discrepancies. Journal of Neuroimaging, 31(5), 814-825. https://doi.org/10.1111/jon.12906
    • Best, J. G., Ambler, G., Wilson, D., Lee, K. J., Lim, J. S., Shiozawa, M., Koga, M., Li, L. X., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martinez-Domeno, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., ... Staals, J. (2021). Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. Lancet Neurology, 20(4), 294-303. https://doi.org/10.1016/S1474-4422(21)00024-7
    • Stevens, R. R. F., Huberts, W., Gommer, E. D., Ertl, M., Aries, M., Mess, W. H., & Delhaas, T. (2021). An Automated Algorithm for Optic Nerve Sheath Diameter Assessment from B-mode Ultrasound Images. Journal of Neuroimaging. https://doi.org/10.1111/jon.12851
    • Florea, A., Kooi, M. E., Mess, W., Schurgers, L. J., Bucerius, J., & Mottaghy, F. M. (2021). Effects of Combined Vitamin K2 and Vitamin D3 Supplementation on Na[18F]F PET/MRI in Patients with Carotid Artery Disease: The INTRICATE Rationale and Trial Design. Nutrients, 13(3), [994]. https://doi.org/10.3390/nu13030994
    • Maalmi, H., Wouters, K., Savelberg, H. H. C. M., van der Velde, J. H. P. M., Reulen, J. P. H., Mess, W., Schalkwijk, C. G., Stehouwer, C. D. A., Roden, M., Ziegler, D., Herder, C., & Schaper, N. C. (2021). Associations of cells from both innate and adaptive immunity with lower nerve conduction velocity: the Maastricht Study. BMJ Open Diabetes Research & Care, 9(1), [001698]. https://doi.org/10.1136/bmjdrc-2020-001698
  • 2020
    • van der Velde, J. H. P. M., Koster, A., Strotmeyer, E. S., Mess, W. H., Hilkman, D., Reulen, J. P. H., Stehouwer, C. D. A., Henry, R. M. A., Schram, M. T., van der Kallen, C. J. H., Schalkwijk, C. G., Savelberg, H. H. C. M., & Schaper, N. C. (2020). Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study. Diabetologia, 63(8), 1648-1658. https://doi.org/10.1007/s00125-020-05194-5
    • Gombert, A., Ruckbeil, M. V., Kotelis, D., Burger, S., Brugmayer, T., Mess, W. H., & Jacobs, M. J. (2020). Assessment of Neurone-Specific Enolase, Glial Fibrillary Acidic Protein and S100 B as Spinal Cord Ischemia Biomarkers in Patients Undergoing Open and Endovascular Complex Aortic Surgery: A Single-Center Experience. Annals of Vascular Surgery, 66, 424-433. https://doi.org/10.1016/j.avsg.2020.01.003
    • Stevens, R. R. F., Donders, W. P., Quicken, S., van de Vosse, F. N., Mess, W. H., Delhaas, T., & Huberts, W. (2020). The Role of One-Dimensional Model-Generated Inter-Subject Variations in Systemic Properties on Wall Shear Stress Indices of Intracranial Aneurysms. Ieee Transactions on Biomedical Engineering, 67(4), 1030-1039. https://doi.org/10.1109/TBME.2019.2928416
    • Oostveen, C. N., Weerwind, P. W., Bergs, P. P. E., Schmidli, J., Buhlmann, R., Schefold, J. C., Eberle, B., Consiglio, J., Schaelte, G., Kotelis, D., Hollands, A. W. H., Buhre, W. F. F. A., Schurink, G. W. H., Jacobs, M. J., van Mook, W. N. K. A., Mess, W. H., & Sutedja, N. A. (2020). Neurophysiological and paraspinal oximetry monitoring to detect spinal cord ischemia in patients during and after descending aortic repair: An international multicenter explorative study. Contemporary Clinical Trials Communications, 17, [100545]. https://doi.org/10.1016/j.conctc.2020.100545