Wouter Huberts

Assistant Professor

Dr Wouter Huberts graduated with a specialisation in medical engineering at the Eindhoven University of Technology (TU/e). Thereafter, he received his PhD degree at Maastricht University based on his thesis entitled 'Personalized modelling of vascular access creation'. Simultaneously, he successfully completed a two-year postdoctoral program (Qualified Medical Engineer at the School of Medical Physics and Engineering, TU/e).

Before that, Dr Wouter Huberts was appointed at the Department of Biomedical Engineering that is chaired by Prof. Tammo Delhaas and is embedded within CARIM, he served two years as a post-doc within the cardiovascular biomechanics group of the TU/e (CVBM chaired by Prof. van de Vosse). Currently, he is still appointed as (visiting) staff member in the CVBM group and he serves as coordinator of the TU/e master medical engineering at the Maastricht University.

Dr Wouter Huberts is amedical engineer who has a large affinity for teaching and has a major interest in the development of personalized physics-based modelling tools to support decision-making in clinics. His interests and expertise are in (computational) fluid mechanics, sensitivity analysis and uncertainty quantification. His current research line ‘Personalized cardiovascular modelling’ is focussed on the development of personalised physics- and physiology-based mathematical models of the cardiovascular system aiming for clinical decision-support.

The development and subsequent application of uncertainty quantification and sensitivity analysis tools are prerequisites when one aims to apply mathematical models for decision support.


Department of Biomedical Engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H3.354
T: +31(0)43 388 16 61

  • 2020
    • Meiburg, R., Huberts, W., Rutten, M. C. M., & van de Vosse, F. N. (2020). Uncertainty in model-based treatment decision support: Applied to aortic valve stenosis. International Journal for Numerical Methods in Biomedical Engineering, 36(10), [3388]. https://doi.org/10.1002/cnm.3388
    • Zonnebeld, N., Tordoir, J. H. M., van Loon, M. M., de Smet, A. A. E. A., Huisman, L. C., Cuypers, P. W. M., Schlosser, F. J., Lemson, S., Heinen, S. G. H., Bouwman, L. H., Toorop, R. J., Huberts, W., Delhaas, T., & Shunt Simulation Study Group (2020). Pre-operative Patient Specific Flow Predictions to Improve Haemodialysis Arteriovenous Fistula Maturation (Shunt Simulation Study): A Randomised Controlled Trial. European Journal of Vascular and Endovascular Surgery, 60(1), 98-106. https://doi.org/10.1016/j.ejvs.2020.03.005
    • van Osta, N., Lyon, A., Kirkels, F., Koopsen, T., van Loon, T., Cramer, M. J., Teske, A. J., Delhaas, T., Huberts, W., & Lumens, J. (2020). Parameter subset reduction for patient-specific modelling of arrhythmogenic cardiomyopathy-related mutation carriers in the CircAdapt model. Philosophical Transactions of the Royal Society A: mathematical Physical and Engineering Sciences, 378(2173), [20190347]. https://doi.org/10.1098/rsta.2019.0347
    • Quicken, S., de Bruin, Y., Mees, B., Tordoir, J., Delhaas, T., & Huberts, W. (2020). Computational study on the haemodynamic and mechanical performance of electrospun polyurethane dialysis grafts. Biomechanics and modeling in mechanobiology, 19(2), 713-722. https://doi.org/10.1007/s10237-019-01242-1
    • Stevens, R. R. F., Donders, W. P., Quicken, S., van de Vosse, F. N., Mess, W. H., Delhaas, T., & Huberts, W. (2020). The Role of One-Dimensional Model-Generated Inter-Subject Variations in Systemic Properties on Wall Shear Stress Indices of Intracranial Aneurysms. Ieee Transactions on Biomedical Engineering, 67(4), 1030-1039. https://doi.org/10.1109/TBME.2019.2928416
    • Quicken, S., Huberts, W., Tordoir, J., van Loon, M., Delhaas, T., & Mees, B. (2020). Computational Modelling Based Recommendation on Optimal Dialysis Needle Positioning and Dialysis Flow in Patients With Arteriovenous Grafts. European Journal of Vascular and Endovascular Surgery, 59(2), 288-294. https://doi.org/10.1016/j.ejvs.2019.08.013
    • Zonnebeld, N., Huberts, W., van Loon, M. M., Delhaas, T., & Tordoir, J. H. M. (2020). Natural Vascular Remodelling After Arteriovenous Fistula Creation in Dialysis Patients With and Without Previous Ipsilateral Vascular Access. European Journal of Vascular and Endovascular Surgery, 59(2), 277-287. https://doi.org/10.1016/j.ejvs.2019.10.010
    • Heinen, S., Gashi, K., van den Heuvel, D., de Vries, J-P., van de Vosse, F., Delhaas, T., & Huberts, W. (2020). A Metamodeling Approach for Instant Severity Assessment and Uncertainty Quantification of Iliac Artery Stenoses. Journal of Biomechanical Engineering-Transactions of the Asme, 142(1), [011010]. https://doi.org/10.1115/1.4044502
  • 2019
    • Hose, D. R., Lawford, P. V., Huberts, W., Hellevik, L. R., Omholt, S. W., & van de Vosse, F. N. (2019). Cardiovascular models for personalised medicine: Where now and where next?Medical Engineering & Physics, 72, 38-48. https://doi.org/10.1016/j.medengphy.2019.08.007
    • Heusinkveld, M. H. G., Delhaas, ET., Lumens, J., Huberts, W., Spronck, B., Hughes, A. D., & Reesink, K. D. (2019). Augmentation index is not a proxy for wave reflection magnitude: mechanistic analysis using a computational model. Journal of Applied Physiology, 127(2), 491-500. https://doi.org/10.1152/japplphysiol.00769.2018