Stem Cell Research University Maastricht (SCRUM)

Initiated by CARIM, in collaboration with FHML, SCRUM is the latest core facility of FHML that will provide service for the generation of induced pluripotent stem cells (iPSC). In this new core facility, iPSC cells provide a solution for research with cells from hard-to-reach tissues such as heart, vascular tissue or brain tissue. These iPSC have the potential to grow into different types of somatic cells. 
 
This state-of-the-art technology will be applied within CARIM to study genetic disorders of heart and vessels, with the ultimate goal to develop new insights and novel therapeutics for cardiovascular disease. In addition, these iPSC derived cells provide an endless supply of cells from the same genetic origin, that can be used for testing pharmacological (drugs) and genetic (CRISPR/Cas9) therapeutic interventions. Further, research within SCRUM aims on possible therapeutic applications of these stem cells for regenerating tissues. In addition to research, SCRUM aims to offer training courses and seminars to stimulate iPSC research culture within Maastricht.
 
Interdisciplinary platforms will be developed within SCRUM in which clinical science and stem cell research will be connected. Within SCRUM, we want to stimulate iPSC research for both fundamental and translational applications between CARIM and HVC.

Watch the video below to know more!

Overview