Barend Mees

Assistant Professor

Dr Barend Mees studied medicine at LUMC in Leiden and completed his training as General and Vascular Surgeon at Erasmus MC in Rotterdam. He subsequently spent almost three years in Melbourne, Australia, to further specialise in Endovascular Surgery. Since May 2014 he has been a consultant Vascular & Endovascular Surgeon in the Department of Vascular Surgery at Maastricht UMC+ and UniKlinik Aachen, Germany. His clinical area of interest is the (endovascular) treatment of (complex) aortic disease and peripheral arterial disease. He is the research coordinator of the Department of Vascular Surgery and has obtained a PhD in Vascular Biology from Erasmus MC, INSERM (U689, Paris) and Max-Planck Institute (Bad Nauheim, Germany).

His main research focus areas are vascular biology, tissue engineering and innovative endovascular techniques. He is member of the leadership of the Cardiovascular Moonshot of RegMedXB and member of the management team of the InScite XS-GRAFT project. He is the inventor of the MAZE Box, a novel hands-on simulator for Endovascular Surgery and tutor for Vascular International. Dr Mees has been examiner of the UEMS FEBVS examination since 2017. He is organiser of the I-MEET congress and co-director of the European Vascular Course.

Department of Vascular Surgery
P. Debeyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T:+31(0)43 387 74 78

  • 2022
    • Kremers, B. M. M., Posma, J. N., Heitmeier, S., Glunz, J., Ten Cate, H., Pallares Robles, A., Daemen, J. H. C., Ten Cate-Hoek, A. J., Mees, B. M. E., & Spronk, H. M. H. (2022). Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease. Scientific Reports, 12(1), [18388]. https://doi.org/10.1038/s41598-022-23260-3
    • Willems, L. H., Maas, D. P. M. S. M., Kramers, K., Reijnen, M. M. P. J., Riksen, N. P., Ten Cate, H., van der Vijver-Coppen, R. J., de Borst, G. J., Mees, B. M. E., Zeebregts, C. J., Hannink, G., & Warlé, M. C. (2022). Correction to: Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs, 82(13), 1435-1435. https://doi.org/10.1007/s40265-022-01776-2
    • Shekarchian, S., Notten, P., Barbati, M. E., Van Laanen, J., Piao, L., Nieman, F., Razavi, M. K., Lao, M., Mees, B., & Jalaie, H. (2022). Development of a prediction model for deep vein thrombosis in a retrospective cohort of patients with suspected deep vein thrombosis in primary care. Journal of Vascular Surgery. Venous and Lymphatic Disorders, 10(5), 1028-1036.e3. https://doi.org/10.1016/j.jvsv.2022.04.009
    • Jin, H., Maas, S. L., Lu, C., Nagenborg, J., Manca, M., Karel, J. M. H., Cavill, R., Waring, O., Sikkink, C. J. J. M., Mees, B. M. E., Daemen, M. J. A. P., Smirnov, E., Sluimer, J., Van der Vorst, E., & Biessen, E. A. L. (2022). Identification Of Cd8+T Cell Prdm1 In High-Risk Human Plaques And Its Regulatory Role In Murine Lesion Development. Atherosclerosis, 355, E9-E9.
    • Willems, L. H., Maas, D. P. M. S. M., Kramers, K., Reijnen, M. M. P. J., Riksen, N. P., Ten Cate, H., van der Vijver-Coppen, R. J., de Borst, G. J., Mees, B. M. W., Zeebregts, C. J., Hannink, G., & Warlé, M. C. (2022). Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs, 82(12), 1287-1302. https://doi.org/10.1007/s40265-022-01756-6
    • Meertens, M. M., Macherey, S., Asselberghs, S., Lee, S., Schipper, J. H., Mees, B., Eitel, I., Baldus, S., Frerker, C., & Schmidt, T. (2022). A systematic review and meta-analysis of the cerebrovascular event incidence after transcatheter aortic valve implantation. Clinical research in cardiology, 111(8), 843-858. https://doi.org/10.1007/s00392-022-01997-1
    • Meertens, M. M., Macherey, S., Asselberghs, S., Lee, S., Schipper, J. H., Mees, B., Eitel, I., Baldus, S., Frerker, C., & Schmidt, T. (2022). Correction: A systematic review and meta-analysis of the cerebrovascular event incidence after transcatheter aortic valve implantation. Clinical research in cardiology, 111(8), 969-970. https://doi.org/10.1007/s00392-022-02018-x
    • Ketting, S., Zoethout, A. C., Heyligers, J. M. M., Wiersema, A. M., Yeung, K. K., Schurink, G. W. H., Verhagen, H. J. M., de Vries, J-P. P. M., Reijnen, M. M. P. J., & Mees, B. M. E. (2022). Nationwide Experience with EVAS Relining of Previous Open or Endovascular AAA Treatment in The Netherlands. Annals of Vascular Surgery, 84, 250-264. https://doi.org/10.1016/j.avsg.2021.12.077
    • Petsophonsakul, P., Burgmaier, M., Willems, B., Heeneman, S., Stadler, N., Gremse, F., Reith, S., Burgmaier, K., Kahles, F., Marx, N., Natour, E., Bidar, E., Jacobs, M., Mees, B., Reutelingsperger, C., Furmanik, M., & Schurgers, L. (2022). Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells. Cardiovascular Research, 118(9), 2196-2210. https://doi.org/10.1093/cvr/cvab244
    • Maas, S. L., Jin, H., Lu, C., Nagenborg, J., Manca, M., Karel, J. M. H., Cavill, R., Waring, O., Sikkink, C. J. J. M., Mees, B. M. E., Daemen, M. J. A. P., Smirnov, E., Sluimer, J., van der Vorst, E. P. C., & Biessen, E. A. L. (2022). Identification of CD8+T cell PRDM1 in high-risk human plaques and its regulatory role in murine lesion development. Cardiovascular Research, 118(SUPPL 1). https://doi.org/10.1093/cvr/cvac066.186
    • Antoniou, G. A., Bastos Gonçalves, F., Björck, M., Chakfé, N., Coscas, R., Dias, N. V., Dick, F., Kakkos, S. K., Mees, B. M. E., Resch, T., Trimarchi, S., Tulamo, R., Twine, C. P., Vermassen, F., Wanhainen, A., & Kolh, P. (2022). Editor's Choice - European Society for Vascular Surgery Clinical Practice Guideline Development Scheme: An Overview of Evidence Quality Assessment Methods, Evidence to Decision Frameworks, and Reporting Standards in Guideline Development. European Journal of Vascular and Endovascular Surgery, 63(6), 791-799. https://doi.org/10.1016/j.ejvs.2022.03.014
    • Simons, J., Agricola, S., Smets, J., Metz, R., Mariani, S., Vleugels, M-J., Smeets, R. R., van Mook, W. N. K. A., Mees, B., & Lorusso, R. (2022). Duplex Analysis of Cannulated Vessels in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation. Medicina-Lithuania, 58(5), [671]. https://doi.org/10.3390/medicina58050671
    • Dewulf, M., De Wever, N., Van Herzeele, I., Mees, B. M. E., Muysoms, F. E., & Bouvy, N. D. (2022). Too Limited Use of Prophylactic Mesh After Open AAA Repair in Belgium and The Netherlands?European Journal of Vascular and Endovascular Surgery, 63(5), 775-776. https://doi.org/10.1016/j.ejvs.2022.02.031
    • Alberga, A. J., von Meijenfeldt, G. C. I., Rastogi, V., de Bruin, J. L., Wever, J. J., van Herwaarden, J. A., Hamming, J. F., Hazenberg, C. E. V. B., van Schaik, J., Mees, B. M. E., van der Laan, M. J., Zeebregts, C. J., Schurink, G. W. H., Verhagen, H. J. M., Dutch Society of Vascular Surgery, Steering Committee of the Dutch Surgical Aneurysm Audit, & Dutch Institute for Clinical Auditing (2022). Association of Hospital Volume with Perioperative Mortality of Endovascular Repair of Complex Aortic Aneurysms: A Nationwide Cohort Study. Annals of Surgery, 75(4), 1492-1492. https://doi.org/10.1097/SLA.0000000000005337
    • van Kuijk, K., Demandt, J. A. F., Perales-Patón, J., Theelen, T. L., Kuppe, C., Marsch, E., de Bruijn, J., Jin, H., Gijbels, M. J., Matic, L., Mees, B. M. E., Reutelingsperger, C. P. M., Hedin, U., Biessen, E. A. L., Carmeliet, P., Baker, A. H., Kramann, R. K., Schurgers, L. J., Saez-Rodriguez, J., & Sluimer, J. C. (2022). Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling. Cardiovascular Research, 118(5), 1232-1246. https://doi.org/10.1093/cvr/cvab152
    • Gombert, A., Ketting, S., Rückbeil, M. V., Hundertmark, A-K., Barbati, M., Keschenau, P., Pedersoli, F., Schurink, G. W., Mees, B., Kotelis, D., & Jacobs, M. J. (2022). Perioperative and long-term outcome after ascending aortic and arch repair with elephant trunk and open thoracoabdominal aortic aneurysm repair. Journal of Vascular Surgery, 75(3), 824-832. https://doi.org/10.1016/j.jvs.2021.09.026
    • Zoethout, A. C., Ketting, S., Zeebregts, C. J., Apostolou, D., Mees, B. M. E., Berg, P., El Beyrouti, H., De Vries, J-P. P. M., Torella, F., Migliari, M., Silingardi, R., & Reijnen, M. M. P. J. (2022). An International, Multicenter Retrospective Observational Study to Assess Technical Success and Clinical Outcomes of Patients Treated with an Endovascular Aneurysm Sealing Device for Type III Endoleak. Journal of Endovascular Therapy, 29(1), 57-65. [15266028211031933]. https://doi.org/10.1177/15266028211031933
    • Shekarchian, S., Notten, P., Barbati, M. E., Razavi, C., Van Laanen, J., Nieman, F., Razavi, M. K., Moossdorff, W., Mees, B., & Jalaie, H. (2022). A risk score for iliofemoral patients with deep vein thrombosis. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 10(1), 33-41.e2. https://doi.org/10.1016/j.jvsv.2021.04.007
    • Hatzl, J., Batenburg, M. V. B., Yeung, K. K., Fioole, B., Verhoeven, E., Lauwers, G., Kölbel, T., Wever, J. J., Scheinert, D., Van den Eynde, W., Rouhani, G., Mees, B. M. E., Vermassen, F., Schelzig, H., Cuypers, P. W. M., Böckler, D., Zephyr study group collaborators, & Schurink, G. (2022). Thirty-day Results from the ZEPHYR Registry: Outcomes of EVAR Using the Zenith Alpha™ Abdominal Endovascular Graft for the Treatment of AAA in 347 Patients. Annals of Vascular Surgery, 78, 170-179. https://doi.org/10.1016/j.avsg.2021.06.020
    • Quicken, S., Mees, B., Zonnebeld, N., Tordoir, J., Huberts, W., & Delhaas, T. (2022). A realistic arteriovenous dialysis graft model for hemodynamic simulations. PLOS ONE, 17(7), [e0269825]. https://doi.org/10.1371/journal.pone.0269825
  • 2021
    • Jin, H., Mees, B., Biessen, E. A., & Sluimer, J. C. (2021). Transcriptional Sex Dimorphism in Human Atherosclerosis Relates to Plaque Type. Circulation Research, 129(12), 1175-1177. https://doi.org/10.1161/circresaha.121.320099
    • van der Beelen, S. H. E., Agten, S. M., Suylen, D. P. L., Wichapong, K., Hrdinova, J., Mees, B. M. E., Spronk, H. M. H., & Hackeng, T. M. (2021). Letter: In response to a recent letter by Prior et al.Thrombosis Research, 207, 66-66. https://doi.org/10.1016/j.thromres.2021.06.017
    • Smeets, R. R., Demir, D., van Laanen, J., Schurink, G. W. H., & Mees, B. M. E. (2021). Use of covered stent grafts as treatment of traumatic venous injury to the inferior vena cava and iliac veins: A systematic review. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 9(6), 1577-+. https://doi.org/10.1016/j.jvsv.2021.03.008
    • Mees, B. M. E., & Oderich, G. S. (2021). Peri-operative Myocardial Injury After Complex Endovascular Aortic Aneurysm Repair: MINS Is Not Meaningless. European Journal of Vascular and Endovascular Surgery, 62(4), 559-560. https://doi.org/10.1016/j.ejvs.2021.07.007
    • Rogers, R. T., Lemmens, C., Farazdaghi, A., Cirillo-Penn, N. C., Mees, B., Tenorio, E. R., Schurink, G. W. H., De Martino, R., Oderich, G. S., & Mendes, B. C. (2021). Fenestrated/Branched Endovascular Aortic Repair Using Unilateral Femoral Access in Patients With Unilateral Iliac Occlusive Disease. Journal of Vascular Surgery, 74(3), E138-E138. https://doi.org/10.1016/j.jvs.2021.06.210
    • Jaminon, A. M. G., Akbulut, A. C., Rapp, N., Kramann, R., Biessen, E. A. L., Temmerman, L., Mees, B., Brandenburg, V., Dzhanaev, R., Jahnen-Dechent, W., Floege, J., Uitto, J., Reutelingsperger, C. P., & Schurgers, L. J. (2021). Development of the BioHybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells and Blood to Measure Vascular Calcification Propensity. Cells, 10(8), [2097]. https://doi.org/10.3390/cells10082097
    • Demir, D., Smeets, R., Schurink, G. W. H., & Mees, B. M. E. (2021). Use of thoracic stent grafts to control major iliac vein bleeding. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 9(4), 1058-1061. https://doi.org/10.1016/j.jvsv.2020.09.012
    • Jin, H., Goossens, P., Juhasz, P., Eijgelaar, W-J., Manca, M., Karel, J., Smirnov, E., Sikkink, C. J. J. M., Mees, B., Waring, O., van Kuijk, K., Fazzi, G., Gijbels, M., Kutmon, M., Evelo, C., Hedin, U., Daemen, M. J., Sluimer, J., Matic, L. P., & Biessen, E. (2021). Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage. Clinical and Translational Medicine, 11(6), [e458]. https://doi.org/10.1002/ctm2.458
    • Mees, B. M. E. (2021). Off the Shelf Fenestrated Stent Grafts: "Mind The Gap?". European Journal of Vascular and Endovascular Surgery, 61(4), 559-559. https://doi.org/10.1016/j.ejvs.2021.02.010
    • van der Beelen, S. H. E., Agten, S. M., Suylen, D. P. L., Wichapong, K., Hrdinova, J., Mees, B. M. E., Spronk, H. M. H., & Hackeng, T. M. (2021). Design and synthesis of a multivalent catch-and-release assay to measure circulating FXIa. Thrombosis Research, 200, 16-22. https://doi.org/10.1016/j.thromres.2021.01.002
    • Mees, B. M. E., da Cunha, G. P., Lemmens, C. C., & Schurink, G. W. H. (2021). Response to: "Re ChEVAR from Below". European Journal of Vascular and Endovascular Surgery, 61(3), 525-526. https://doi.org/10.1016/j.ejvs.2020.11.005
    • Simons, J., Suverein, M., van Mook, W., Caliskan, K., Soliman, O., van de Poll, M., Delnoij, T., Maessen, J., Mees, B., & Lorusso, R. (2021). Do-(Not-)Mechanical-Circulatory-Support Orders: Should We Ask All Cardiac Surgery Patients for Informed Consent for Post-Cardiotomy Extracorporeal Life Circulatory Support?Journal of Clinical Medicine, 10(3), [383]. https://doi.org/10.3390/jcm10030383
    • Snoeijs, M. G., & Mees, B. M. E. (2021). Response to "Re The Effect of Geometrical Graft Modification on Arteriovenous Graft Patency in Haemodialysis Patients: A Systematic Review and Meta-Analysis". European Journal of Vascular and Endovascular Surgery, 61(2), 346-347. https://doi.org/10.1016/j.ejvs.2020.10.003
    • Quicken, S., Delhaas, T., Mees, B. M. E., & Huberts, W. (2021). Haemodynamic optimisation of a dialysis graft design using a global optimisation approach. International Journal for Numerical Methods in Biomedical Engineering, 37(2), [e3423]. https://doi.org/10.1002/cnm.3423
    • Wubbeke, L. F., Kremers, B., Daemen, J-W. H. C., Snoeijs, M. G. J., Jacobs, M. J., & Mees, B. M. E. (2021). Mortality in Octogenarians With Chronic Limb Threatening Ischaemia After Revascularisation or Conservative Therapy Alone. European Journal of Vascular and Endovascular Surgery, 61(2), 350-351. https://doi.org/10.1016/j.ejvs.2020.09.018
    • Demandt, J. A. F., Dubois, L. J., van Kuijk, K., Zat'ovicova, M., Jin, H., Parkkila, S., van der Laan, S. W., Jelenska, L., Mees, B. M. E., Reutelingsperger, C. P. M., Cleutjens, K. B. J. M., van der Kallen, C. J. H., Schalkwijk, C. G., van Greevenbroek, M. M. J., Biessen, E. A. L., Pasterkamp, G., Pastorekova, S., Stehouwer, C. D. A., & Sluimer, J. C. (2021). The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease. Scientific Reports, 11(1), [425]. https://doi.org/10.1038/s41598-020-79978-5
  • 2020
    • Mees, B. M. E. (2020). European Collaborations on Thoraco-Abdominal Aortic Aneurysm Repair: "We Want More!". European Journal of Vascular and Endovascular Surgery, 60(6), 853. https://doi.org/10.1016/j.ejvs.2020.09.005
    • da Cunha, G. P., Lemmens, C. C., & Mees, B. M. E. (2020). Chimney Endovascular Aneurysm Repair from Below. European Journal of Vascular and Endovascular Surgery, 60(5), 780-780. https://doi.org/10.1016/j.ejvs.2020.08.019
    • Yazar, O., Mees, B. M. E., Provoost, A-L., Ketting, S., de Haan, M. W., & Schurink, G. W. H. (2020). Comparing Mobile C-Arm with a Hybrid Operating Room for Imaging in Fenestrated Stent-Graft Endovascular Abdominal Aortic Aneurysm Repair. Annals of Vascular Surgery, 68, 261-269. https://doi.org/10.1016/j.avsg.2020.04.002
    • Heuts, S., Sprooten, R. T. M., Heines, S. J. H., & Mees, B. M. E. (2020). Mechanical ventilation variability due to tracheal compression in a patient with a mycotic descending aortic aneurysm: an inverse correlation with blood pressure. European Journal of Cardio-Thoracic Surgery, 58(4), 864-866. https://doi.org/10.1093/ejcts/ezaa126
    • Sawo, P., Moufarrej, A., Sloff, M., Snoeijs, M. G., Delhaas, T., Tordoir, J. H. M., & Mees, B. M. E. (2020). The Effect of Geometric Graft Modification on Arteriovenous Graft Patency in Haemodialysis Patients: A Systematic Review and Meta-Analysis. European Journal of Vascular and Endovascular Surgery, 60(4), 568-577. https://doi.org/10.1016/j.ejvs.2020.06.023
    • Furmanik, M., Chatrou, M., van Gorp, R., Akbulut, A., Willems, B., Schmidt, H., van Eys, G., Bochaton-Piallat, M-L., Proudfoot, D., Biessen, E., Hedin, U., Perisic, L., Mees, B., Shanahan, C., Reutelingsperger, C., & Schurgers, L. (2020). Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification. Circulation Research, 127(7), 911-927. https://doi.org/10.1161/CIRCRESAHA.119.316159
    • Field, J., Ketting, S., Schurink, G. W. H., & Mees, B. M. E. (2020). Ongoing migration of chimney endovascular aneurysm sealing. Journal of Vascular Surgery Cases and Innovative Techniques, 6(3), 443-443. https://doi.org/10.1016/j.jvscit.2020.06.005
    • Wubbeke, L. F., Conings, J. Z. M., Elshof, J-W., Scheltinga, M. R., Daemen, J-W. H. C., Jacobs, M. J., & Mees, B. M. (2020). Outcome of rectus femoris muscle flaps for groin coverage after vascular surgery. Journal of Vascular Surgery, 72(3), 1050-1057.e2. https://doi.org/10.1016/j.jvs.2019.11.031
    • Kremers, B., Wubbeke, L., Mees, B., ten Cate, H., Spronk, H., & ten Cate-Hoek, A. (2020). Plasma Biomarkers to Predict Cardiovascular Outcome in Patients With Peripheral Artery Disease A Systematic Review and Meta-Analysis. Arteriosclerosis Thrombosis and Vascular Biology, 40(9), 2018-2032. https://doi.org/10.1161/ATVBAHA.120.314774
    • Mommers, E. H. H., van Kooten, L., Nienhuijs, S. W., Reilingh, T. S. D., Lubbers, T., Mees, B. M. E., Schurink, G. W. H., & Bouvy, N. D. (2020). Can Electric Nose Breath Analysis Identify Abdominal Wall Hernia Recurrence and Aortic Aneurysms? A Proof-of-Concept Study. Surgical Innovation, 27(4), 366-372. [1553350620917898]. https://doi.org/10.1177/1553350620917898
    • Wubbeke, L. F., Naves, C. C. L. M., Daemen, J. W. H. C., Jacobs, M. J., & Mees, B. M. E. (2020). Editor's Choice – Mortality and Major Amputation after Revascularisation in Octogenarians Versus Non-Octogenarians with Chronic Limb Threatening Ischaemia: A Systematic Review and Meta-Analysis. European Journal of Vascular and Endovascular Surgery, 60(2), 231-241. https://doi.org/10.1016/j.ejvs.2020.04.027
    • Mees, B. M. E., Wubbeke, L. F., & Daemen, J. W. H. C. (2020). Re "Gentamicin Containing Collagen Implants and Groin Wound Infections in Vascular Surgery: A Prospective Randomised Controlled Multicentre Trial". European Journal of Vascular and Endovascular Surgery, 60(2), 318-319. https://doi.org/10.1016/j.ejvs.2020.04.023
    • De Boer, S. W., Heinen, S. G. H., Goudeketting, S. R., De Haan, M. W., Mees, B. M., Van Den Heuvel, D. A. F., & De Vries, J-P. P. M. (2020). Novel diagnostic and imaging techniques in endovascular iliac artery procedures. Expert review of cardiovascular therapy, 18(7), 395-404. https://doi.org/10.1080/14779072.2020.1780916
    • Lemmens, C. C., Mees, B. M. E., de Haan, M. W., & Schurink, G. W. H. (2020). Stabilization of a steerable sheath during retrograde access to antegrade-oriented branches in complex endovascular aortic aneurysm repair. Journal of Vascular Surgery Cases and Innovative Techniques, 6(2), 288-291. https://doi.org/10.1016/j.jvscit.2020.03.014