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Professorship Julie Staals

Professorship Julie Staals

22 April 2024

Dr Julie Staals (Dept. of Neurology) has been appointed as professor 'Neurovascular disease' as of 1 April 2024.

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ERC Advanced Grant awarded to Prof. Andy Baker

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Prof. Andy Baker (Dept of Pathology) has been awarded a European Research Council (ERC) Advanced Grant of €2,5M for his research project PolymiRize: Poly-miRNA targeting to prevent and reverse complex tissue remodelling after acute cardiovascular events'.

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Carim Maastricht
Carim Maastricht

Christian Weber

Professor

Prof. Christian Weber is the Chair in Vascular Medicine and the Director of the Institute for Cardiovascular Prevention at Ludwig-Maximilians-University (LMU) Munich, Germany, and Professor at the CARIM. After graduating and completing his training in internal medicine at LMU and Harvard Medical School, Boston, he was board-certified in clinical cardiology and appointed as a Chair in Molecular Cardiology at RWTH Aachen University. His group has a strong interest in the molecular interactions and patho-physiological functions of chemokines and immune cell subsets, as well as the role of microRNAs and their targets in vascular disease and atherosclerosis, while his clinical interests focus on developing novel biomarkers and biopharmaceuticals. He is the Spokesman of the DFG Collaborative Research Centre SFB1123 and coordinates the partner site Munich Heart Alliance in the German Centre for Cardiovascular Research (DZHK). Among numerous awards, he is a double ERC Advanced Investigator Grant recipient and Clarivate Analytics Highly Cited Researcher with more than 560 publications and an h-index of 97. He serves as the Editor-in-Chiefof Thrombosis&Haemostasis, Senior Associate Editor of Arteriosclerosis, Thrombosis & Vascular Biology andco-founderofCarolusTherapeutics Inc. and Cartesio Therapeutics Inc.

  • Vascular Immunotherapy, German Centre for Cardiovascular Research (BMBF DZHK
  • MHA VD1.2), 2019-2020
  • Munich Cluster for Systems Neurology (SyNergy), DFG Excellence Initiative, 2019-2026
  • ERC Advanced Grant °692511, PROVASC: Cell-specific vascular protection by CXCL12/CXCR4, 2016- 2022 ERC AdG
  • NIH 1R01HL122843, Molecular mechanisms linking CXCL12 to atherosclerosis, 2017-2020
  • DFG Collaborative Research Centre 1123 Atherosclerosis: new therapeutic targets, 2014-2022
Christian-weber

Department of Biochemistry
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2019
    • Lutgens, E., Atzler, D., Doering, Y., Duchene, J., Steffens, S., & Weber, C. (2019). Immunotherapy for cardiovascular disease. European Heart Journal, 40(48), 3937-3946. https://doi.org/10.1093/eurheartj/ehz283
    • Goldmann, L., Duan, R., Kragh, T., Wittmann, G., Weber, C., Lorenz, R., von Hundelshausen, P., Spannagl, M., & Siess, W. (2019). Oral Bruton tyrosine kinase inhibitors block activation of the platelet Fc receptor CD32a (FcγRIIA): a new option in HIT?Blood advances, 3(23), 4021-4033. https://doi.org/10.1182/bloodadvances.2019000617
    • Cimen, I., Yildirim, Z., Dogan, A. E., Yildirim, A. D., Tufanli, O., Onat, U. I., UyenThao Nguyen, Watkins, S. M., Weber, C., & Erbay, E. (2019). Double bond configuration of palmitoleate is critical for atheroprotection. Molecular Metabolism, 28, 58-72. https://doi.org/10.1016/j.molmet.2019.08.004
    • Busygina, K., Denzinger, V., Bernlochner, I., Weber, C., Lorenz, R., & Siess, W. (2019). Btk Inhibitors as First Oral Atherothrombosis-Selective Antiplatelet Drugs?Thrombosis and Haemostasis, 119(8), 1212-1221. https://doi.org/10.1055/s-0039-1687877
    • Natarelli, L., & Weber, C. (2019). Next-Generation Therapeutic Concepts for Atherosclerosis: Focus on Cell Specificity and Noncoding RNAs. Thrombosis and Haemostasis, 119(8), 1199-1201. https://doi.org/10.1055/s-0039-1693412
    • Nagy, M., van Geffen, J. P., Stegner, D., Adams, D. J., Braun, A., de Witt, S. M., Elvers, M., Geer, M. J., Kuijpers, M. J. E., Kunzelmann, K., Mori, J., Oury, C., Pircher, J., Pleines, I., Poole, A. W., Senis, Y. A., Verdoold, R., Weber, C., Nieswandt, B., ... Baaten, C. C. F. M. J. (2019). Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. Frontiers in Cardiovascular Medicine, 6, Article 99. https://doi.org/10.3389/fcvm.2019.00099
    • Ketelhuth, D. F. J., Lutgens, E., Back, M., Binder, C. J., Van den Bossche, J., Daniel, C., Dumitriu, I. E., Hoefer, I., Libby, P., O'Neill, L., Weber, C., & Evans, P. C. (2019). Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology. Cardiovascular Research, 115(9), 1385-1392. https://doi.org/10.1093/cvr/cvz166
    • Bianchini, M., Duchene, J., Santovito, D., Schloss, M. J., Evrard, M., Winkels, H., Aslani, M., Mohanta, S. K., Horckmans, M., Blanchet, X., Lacy, M., von Hundelshausen, P., Atzler, D., Habenicht, A., Gerdes, N., Pelisek, J., Ng, L. G., Steffens, S., Weber, C., & Megens, R. T. A. (2019). PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function. Science Immunology, 4(36), Article 3054. https://doi.org/10.1126/sciimmunol.aar3054
    • van der Vorst, E. P. C., Peters, L. J. F., Mueller, M., Gencer, S., Yan, Y., Weber, C., & Döring , Y. (2019). G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis. Frontiers in Pharmacology, 10, Article 531. https://doi.org/10.3389/fphar.2019.00531
    • Silvestre-Roig, C., Braster, Q., Wichapong, K., Lee, E. Y., Marie Teulon, J., Berrebeh, N., Winter, J., Adrover, J. M., Santos, G. S., Froese, A., Lemnitzer, P., Ortega-Gomez, A., Chevre, R., Marschner, J., Schumski, A., Winter, C., Perez-Olivares, L., Pan, C., Paulin, N., ... Soehnlein, O. (2019). Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature, 569(7755), 236-240. https://doi.org/10.1038/s41586-019-1167-6
    • Gencer, S., van der Vorst, E. P. C., Aslani, M., Weber, C., Döring, Y., & Duchene, J. (2019). Atypical Chemokine Receptors in Cardiovascular Disease. Thrombosis and Haemostasis, 119(4), 534-541. https://doi.org/10.1055/s-0038-1676988
    • Noels, H., Weber, C., & Koenen, R. R. (2019). Chemokines as Therapeutic Targets in Cardiovascular Disease The Road Behind, The Road Ahead. Arteriosclerosis Thrombosis and Vascular Biology, 39(4), 583-592. https://doi.org/10.1161/ATVBAHA.118.312037
    • van der Vorst, E. P. C., Mandl, M., Mueller, M., Neideck, C., Jansen, Y., Hristov, M., Gencer, S., Peters, L. J. F., Meiler, S., Feld, M., Geiselhoeringer, A.-L., de Jong, R. J., Ohnmacht, C., Noels, H., Soehnlein, O., Drechsler, M., Weber, C., & Doering, Y. (2019). Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 39(4), 685-693. https://doi.org/10.1161/ATVBAHA.119.312386
    • Steffens, S., & Weber, C. (2019). Immunotherapy for Atherosclerosis-Novel Concepts. Thrombosis and Haemostasis, 119(4), 515-516. https://doi.org/10.1055/s-0039-1683451
    • Döring, Y., van der Vorst, E. P. C., Duchene, J., Jansen, Y., Gencer, S., Bidzhekov, K., Atzler, D., Santovito, D., Rader, D. J., Saleheen, D., & Weber, C. (2019). CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease. Circulation, 139(10), 1338-1340. https://doi.org/10.1161/CIRCULATIONAHA.118.037953
    • Cremer, S., Michalik, K. M., Fischer, A., Pfisterer, L., Jae, N., Winter, C., Boon, R. A., Muhly-Reinholz, M., John, D., Uchida, S., Weber, C., Poller, W., Guenther, S., Braun, T., Li, D. Y., Maegdefessel, L., Matic, L. P., Hedin, U., Soehnlein, O., ... Dimmeler, S. (2019). Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation. Circulation, 139(10), 1320-1334. https://doi.org/10.1161/circulationaha.117.029015
    • Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H.-H., Pelisek, J., ... Habenicht, A. J. R. (2019). ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine, 25(3), 496-506. https://doi.org/10.1038/s41591-018-0336-8
    • Schloss, M. J., Horckmans, M., Guillamat-Prats, R., Hering, D., Lauer, E., Lenglet, S., Weber, C., Thomas, A., & Steffens, S. (2019). 2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction. Cardiovascular Research, 115(3), 602-613. https://doi.org/10.1093/cvr/cvy242
    • Denzinger, V., Busygina, K., Jamasbi, J., Pekrul, I., Spannagl, M., Weber, C., Lorenz, R., & Siess, W. (2019). Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. Thrombosis and Haemostasis, 119(3), 397-406. https://doi.org/10.1055/s-0039-1677744
    • Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H.-H., Pelisek, J., ... Habenicht, A. J. R. (2019). Publisher Correction: ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine, 25(3), 529-529. https://doi.org/10.1038/s41591-019-0378-6
    • Adrover, J. M., del Fresno, C., Crainiciuc, G., Isabel Cuartero, M., Casanova-Acebes, M., Weiss, L. A., Huerga-Encabo, H., Silvestre-Roig, C., Rossaint, J., Cossio, I., Lechuga-Vieco, A. V., Garcia-Prieto, J., Gomez-Parrizas, M., Quintana, J. A., Ballesteros, I., Martin-Salamanca, S., Aroca-Crevillen, A., Chong, S. Z., Evrard, M., ... Hidalgo, A. (2019). A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity, 50(2), 390-402.e10. https://doi.org/10.1016/j.immuni.2019.01.002
    • Pfeiler, S., Thakur, M., Gruenauer, P., Megens, R. T. A., Joshi, U., Coletti, R., Samara, V., Mueller-Stoy, G., Ishikawa-Ankerhold, H., Stark, K., Klingl, A., Froehlich, T., Arnold, G. J., Woermann, S., Bruns, C. J., Alguel, H., Weber, C., Massberg, S., & Engelmann, B. (2019). CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis. Faseb Journal, 33(2), 1860-1872. https://doi.org/10.1096/fj.201800985R
    • Prats, R. G., Rami, M., Ring, L., Rinne, P., Lauer, E., Lenglet, S., Thomas, A., Pagano, S., Vuilleumier, N., Cravatt, B. F., Weber, C., Faussner, A., & Steffens, S. (2019). Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner. Thrombosis and Haemostasis, 119(2), 348-351. https://doi.org/10.1055/s-0038-1676769
    • van der Vorst, E. P. C., & Weber, C. (2019). Novel Features of Monocytes and Macrophages in Cardiovascular Biology and Disease. Arteriosclerosis Thrombosis and Vascular Biology, 39(2), E30-E37. https://doi.org/10.1161/ATVBAHA.118.312002
    • Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slutter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. K., Nicolaes, G. A. F., ... Lutgens, E. (2019). Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death. European Heart Journal, 40(4), 372-382. https://doi.org/10.1093/eurheartj/ehy714
    • Kiouptsi, K., Jaeckel, S., Pontarollo, G., Grill, A., Kuijpers, M. J. E., Wilms, E., Weber, C., Sommer, F., Nagy, M., Neideck, C., Jansen, Y., Ascher, S., Formes, H., Karwot, C., Bayer, F., Kollar, B., Subramaniam, S., Molitor, M., Wenzel, P., ... Reinhardt, C. (2019). The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. Mbio, 10(5), Article e02298-19. https://doi.org/10.1128/mBio.02298-19
  • 2018
    • Stocker, T. J., Pircher, J., Skenderi, A., Ehrlich, A., Eberle, C., Megens, R. T. A., Petzold, T., Zhang, Z., Walzog, B., Mueller-Taubenberger, A., Weber, C., Massberg, S., Ishikawa-Ankerhold, H., & Schulz, C. (2018). The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis. Thrombosis and Haemostasis, 118(12), 2098-2111. https://doi.org/10.1055/s-0038-1675604
    • Braza, M. S., van Leent, M. M. T., Lameijer, M., Sanchez-Gaytan, B. L., Arts, R. J. W., Perez-Medina, C., Conde, P., Garcia, M. R., Gonzalez-Perez, M., Brahmachary, M., Fay, F., Kluza, E., Kossatz, S., Dress, R. J., Salem, F., Rialdi, A., Reiner, T., Boros, P., Strijkers, G. J., ... Ochando, J. (2018). Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity, 49(5), 819-828.e6. https://doi.org/10.1016/j.immuni.2018.09.008
    • Casanova-Acebes, M., Nicolas-Avila, J. A., Li, J. L., Garcia-Silva, S., Balachander, A., Rubio-Ponce, A., Weiss, L. A., Adrover, J. M., Burrows, K., A-Gonzalez, N., Ballesteros, I., Devi, S., Quintana, J. A., Crainiciuc, G., Leiva, M., Gunzer, M., Weber, C., Nagasawa, T., Soehnlein, O., ... Hidalgo, A. (2018). Neutrophils instruct homeostatic and pathological states in naive tissues. Journal of Experimental Medicine, 215(11), 2778-2795. https://doi.org/10.1084/jem.20181468
    • Rinne, P., Guillamat-Prats, R., Rami, M., Bindila, L., Ring, L., Lyytikainen, L.-P., Raitoharju, E., Oksala, N., Lehtimaki, T., Weber, C., van der Vorst, E. P. C., & Steffens, S. (2018). Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation. Arteriosclerosis Thrombosis and Vascular Biology, 38(11), 2562-2575. https://doi.org/10.1161/ATVBAHA.118.311185
    • Schmitz, C., Noels, H., El Bounkari, O., Straussfeld, E., Megens, R. T. A., Sternkopf, M., Alampour-Rajabi, S., Krammer, C., Tilstam, P. V., Gerdes, N., Burger, C., Kapurniotu, A., Bucala, R., Jankowski, J., Weber, C., & Bernhagen, J. (2018). Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. Faseb Journal, 32(8), 4428-4443. https://doi.org/10.1096/fj.201800058R
    • Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8, Article 10647. https://doi.org/10.1038/s41598-018-29026-0
    • Domschke, G., Linden, F., Pawig, L., Hafner, A., Akhavanpoor, M., Reymann, J., Doesch, A. O., Erbel, C., Weber, C., Katus, H. A., Noels, H., Erfle, H., Gleissner, C. A., & Runz, H. (2018). Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Scientific Reports, 8, Article 10516. https://doi.org/10.1038/s41598-018-28790-3
    • Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G. A. F., Weber, C., Viola, J. R., Hidalgo, A., Scheiermann, C., & Soehnlein, O. (2018). Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism, 28(1), 175-182.e5. https://doi.org/10.1016/j.cmet.2018.05.002
    • van der Vorst, E. P. C., Weber, C., & Donners, M. M. P. C. (2018). A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches. Thrombosis and Haemostasis, 118(7), 1167-1175. https://doi.org/10.1055/s-0038-1660479
    • van der Vorst, E. P. C., & Weber, C. (2018). Metabolomic profiling of atherosclerotic plaques: towards improved cardiovascular risk stratification. European Heart Journal, 39(24), 2311-2313. https://doi.org/10.1093/eurheartj/ehy117
    • Busygina, K., Jamasbi, J., Seiler, T., Deckmyn, H., Weber, C., Brandl, R., Lorenz, R., & Siess, W. (2018). Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans. Blood, 131(24), 2605-2616. https://doi.org/10.1182/blood-2017-09-808808
    • Tunon, J., Back, M., Badimon, L., Bochaton-Piallat, M.-L., Cariou, B., Daemen, M. J., Egido, J., Evans, P. C., Francis, S. E., Ketelhuth, D. F. J., Lutgens, E., Matter, C. M., Monaco, C., Steffens, S., Stroes, E., Vindis, C., Weber, C., Hoefer, I. E., & ESC Working Grp Atherosclerosis (2018). Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. European Journal of Preventive Cardiology, 25(9), 948-955. https://doi.org/10.1177/2047487318773384
    • Rami, M., Guillamat-Prats, R., Rinne, P., Salvermoser, M., Ring, L., Bianchini, M., Blanchet, X., Megens, R. T. A., Doring, Y., Walzog, B., Soehnlein, O., Weber, C., Faussner, A., & Steffens, S. (2018). Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1007-1019. https://doi.org/10.1161/ATVBAHA.117.310536
    • Lacy, M., Kontos, C., Brandhofer, M., Hille, K., Groning, S., Sinitski, D., Bourilhon, P., Rosenberg, E., Krammer, C., Thavayogarajah, T., Pantouris, G., Bakou, M., Weber, C., Lolis, E., Bernhagen, J., & Kapurniotu, A. (2018). Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Scientific Reports, 8, Article 5171. https://doi.org/10.1038/s41598-018-23554-5
    • Horckmans, M., Bianchini, M., Santovito, D., Megens, R. T. A., Springael, J.-Y., Negri, I., Vacca, M., Di Eusanio, M., Moschetta, A., Weber, C., Duchene, J., & Steffens, S. (2018). Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction. Circulation, 137(9), 948-960. https://doi.org/10.1161/CIRCULATIONAHA.117.028833
    • Seijkens, T. T. P., van Tiel, C. M., Kusters, P. J. H., Atzler, D., Soehnlein, O., Zarzycka, B., Aarts, S. A. B. M., Lameijer, M., Gijbels, M. J., Beckers, L., den Toom, M., Slutter, B., Kuiper, J., Duchene, J., Aslani, M., Megens, R. T. A., van 't Veer, C., Kooij, G., Schrijver, R., ... Lutgens, E. (2018). Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. Journal of the American College of Cardiology, 71(5), 527-542. https://doi.org/10.1016/j.jacc.2017.11.055
    • Ebrahim, M., Jamasbi, J., Adler, K., Megens, R. T. A., M'Bengue, Y., Blanchet, X., Uhland, K., Ungerer, M., Brandl, R., Weber, C., Elia, N., Lorenz, R., Muench, G., & Siess, W. (2018). Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin. Thrombosis and Haemostasis, 118(2), 351-361. https://doi.org/10.1160/TH17-04-0302
    • Curaj, A., Wu, Z., Rix, A., Gresch, O., Sternkopf, M., Alampour-Rajabi, S., Lammers, T., van Zandvoort, M., Weber, C., Koenen, R. R., Liehn, E. A., & Kiessling, F. (2018). Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation. Arteriosclerosis Thrombosis and Vascular Biology, 38(1), 40-48. https://doi.org/10.1161/ATVBAHA.117.309503
  • 2017
    • Winkels, H., Meiler, S., Lievens, D., Engel, D., Spitz, C., Buerger, C., Beckers, L., Dandl, A., Reim, S., Ahmadsei, M., Hartwig, H., Holdt, L. M., Hristov, M., Megens, R. T. A., Schmitt, M. M., Biessen, E. A., Borst, J., Faussner, A., Weber, C., ... Gerdes, N. (2017). CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice. European Heart Journal, 38(48), 3590-3599. https://doi.org/10.1093/eurheartj/ehx517
    • Kusters, P., Seijkens, T., Buerger, C., Legein, B., Winkels, H., Gijbels, M., Barthels, C., Bennett, R., Beckers, L., Atzler, D., Biessen, E., Brocker, T., Weber, C., Gerdes, N., & Lutgenst, E. (2017). Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption. American Journal of Pathology, 187(12), 2912-2919. https://doi.org/10.1016/j.ajpath.2017.08.016
    • Wu, Z., Rademakers, T., Kiessling, F., Vogt, M., Westein, E., Weber, C., Megens, R. T. A., & van Zandvoort, M. (2017). Multi-photon microscopy in cardiovascular research. Methods, 130, 79-89. https://doi.org/10.1016/j.ymeth.2017.04.013
    • Weber, C., & von Hundelshausen, P. (2017). CANTOS Trial Validates the Inflammatory Pathogenesis of Atherosclerosis Setting the Stage for a New Chapter in Therapeutic Targeting. Circulation Research, 121(10), 1119-1121. https://doi.org/10.1161/CIRCRESAHA.117.311984
    • Krishnasamy, K., Limbourg, A., Kapanadze, T., Gamrekelashvili, J., Beger, C., Haeger, C., Lozanovski, V. J., Falk, C. S., Napp, L. C., Bauersachs, J., Mack, M., Haller, H., Weber, C., Adams, R. H., & Limbourg, F. P. (2017). Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia. Nature Communications, 8, Article 952. https://doi.org/10.1038/s41467-017-00953-2
    • Theodorou, K., van der Vorst, E. P. C., Gijbels, M. J., Wolfs, I. M. J., Jeurissen, M., Theelen, T. L., Sluimer, J. C., Wijnands, E., Cleutjens, J. P., Li, Y., Jansen, Y., Weber, C., Ludwig, A., Bentzon, J. F., Bartsch, J. W., Biessen, E. A. L., & Donners, M. M. P. C. (2017). Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression. Scientific Reports, 7, Article 11670. https://doi.org/10.1038/s41598-017-10549-x
Overview