Joachim Wildberger


Joachim Wildberger is full Professor of Radiology and Chairman of the Department of Radiology and Nuclear Medicine at Maastricht UMC+. In addition, he serves as Director of the Division of Clinical Imaging and Diagnostic Laboratories at Maastrcith UMC+.

Graduated at the Rhenian-Westphalian Technical University (RWTH) in Aachen, Germany, he received his medical degree in 1994. After internships in Cardiology and Diagnostic Radiology (Mönchengladbach/ Leipzig), he started his residency in Diagnostic Radiology at the University Hospital Aachen. He was board certified for Diagnostic Radiology in December 1998, and became a fellow/staff member at this department thereafter. He received his PhD in Radiology in 2002, was appointed as vice-chairman of the department in 2006 and received a professorship at the RWTH Aachen in 2007. In July 2007 he became Head of Department, Diagnostic Radiology, HELIOS Klinikum Berlin-Buch, Charité Berlin, Campus Buch, Germany, before moving to his present position.

His per personal research topics are technical developments and functional imaging in computed tomography, contrast media research, cardiac imaging as well as image-guided interventions.

As PI for Imaging within CARIM he focusses on translational research, integrating different imaging modalities into the cardiovascular diagnostic chain, and favours multidisciplinary approaches to improve patient care.

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 4.G2.013
T: +31(0)43 387 49 12

  • 2020
    • Veeraiah, P., Brouwers, K., Wildberger, J. E., Schrauwen-Hinderling, V. B., & Lindeboom, L. (2020). Application of a BIlinear Rotation Decoupling (BIRD) filter in combination with J-difference editing for indirect 13 C measurements in the human liver. Magnetic Resonance in Medicine, 84(6), 2911-2917.
    • Bruggemann, R. A. G., Spaetgens, B., Gietema, H. A., Brouns, S. H. A., Stassen, P. M., Magdelijns, F. J., Rennenberg, R. J., Henry, R. M. A., Mulder, M. M. G., van Bussel, B. C. T., Schnabel, R. M., van der Horst, I. C. C., Wildberger, J. E., Stehouwer, C. D. A., & ten Cate, H. (2020). The prevalence of pulmonary embolism in patients with COVID-19 and respiratory decline: A three-setting comparison. Thrombosis Research, 196, 486-490.
    • Vargas, C. S., Bauwens, M., Pooters, I. N. A., Pomme, S., Peters, S. M. B., Segbers, M., Jentzen, W., Vogg, A., van Velden, F. H. P., Viol, S. L. M., Gotthardt, M., Mottaghy, F. M., Wildberger, J. E., Covens, P., & Wierts, R. (2020). An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theragnostics. EJNMMI Physics, 7(1), [69].
    • Martens, B., Wildberger, J. E., Hendriks, B. M. F., Van Kuijk, S. M. J., Nijssen, E. C., Peters, N. H. G. M., De Vos-Geelen, J., & Mihl, C. (2020). A Solution for Homogeneous Liver Enhancement in Computed Tomography Results From the COMpLEx Trial. Investigative Radiology, 55(10), 666-672.
    • Martens, B., Hendriks, B. M. F., Mihl, C., & Wildberger, J. E. (2020). Tailoring Contrast Media Protocols to Varying Tube Voltages in Vascular and Parenchymal CT Imaging The 10-to-10 Rule. Investigative Radiology, 55(10), 673-676.
    • Bruls, Y. M. H., Op den Kamp, Y. J. M., Phielix, E., Lindeboom, L., Havekes, B., Schaart, G., Moonen-Kornips, E., Wildberger, J. E., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2020). L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility. PLOS ONE, 15(9), [0239506].
    • Wildberger, J. E., & Prokop, M. (2020). Hounsfield's Legacy. Investigative Radiology, 55(9), 556-558.
    • Eijsvoogel, N. G., Hendriks, B. M. F., Martens, B., Gerretsen, S. C., Gommers, S., van Kuijk, S. M. J., Mihl, C., Wildberger, J. E., & Das, M. (2020). The performance of non-ECG gated chest CT for cardiac assessment: The cardiac pathologies in chest CT (CaPaCT) study. European Journal of Radiology, 130, [109151].
    • de Wit-Verheggen, V. H. W., Altintas, S., Spee, R. J. M., Mihl, C., van Kuijk, S. M. J., Wildberger, J. E., Schrauwen-Hinderling, V. B., Kietselaer, B. L. J. H., & van de Weijer, T. (2020). Pericardial fat and its influence on cardiac diastolic function. Cardiovascular Diabetology, 19(1), [129].
    • Peeters, F. E. C. M., Dudink, E. A. M. P., Weijs, B., Fabritz, L., Chua, W., Kietselaer, B. L. J. H., Wildberger, J. E., Meex, S. J. R., Kirchhof, P., Crijns, H. J. G. M., & Schurgers, L. J. (2020). Biomarkers Associated With Aortic Valve Calcification: Should We Focus on Sex Specific Processes?Frontiers in Cell and Developmental Biology, 8, [604].
    • Gietema, H. A., Zelis, N., Nobel, J. M., Lambriks, L. J. G., van Alphen, L. B., Lashof, A. M. L. O., Wildberger, J. E., Nelissen, I. C., & Stassen, P. M. (2020). CT in relation to RT-PCR in diagnosing COVID-19 in The Netherlands: A prospective study. PLOS ONE, 15(7), [0235844].
    • Nijssen, E. C., Nelemans, P. J., Rennenberg, R. J., van der Molen, A. J., van Ommen, G. V., & Wildberger, J. E. (2020). Impact on clinical practice of updated guidelines on iodinated contrast material: CINART. European Radiology, 30(7), 4005-4013.
    • Heuts, S., Adriaans, B. P., Rylski, B., Mihl, C., Bekkers, S. C. A. M., Olsthoorn, J. R., Natour, E., Bouman, H., Berezowski, M., Kosiorowska, K., Crijns, H. J. G. M., Maessen, J. G., Wildberger, J., Schalla, S., & Nia, P. S. (2020). Evaluating the diagnostic accuracy of maximal aortic diameter, length and volume for prediction of aortic dissection. Heart, 106(12), 892-897.
    • Horehledova, B., Mihl, C., Boswijk, E., Crombag, G. A. J. C., Nijssen, E. C., Nelemans, P. J., Veenstra, L. F., Wildberger, J. E., & Das, M. (2020). Retrospectively ECG-gated helical vs. non-ECG-synchronized high-pitch CTA of the aortic root for TAVI planning. PLOS ONE, 15(5), [0232673].
    • Reymen, B. J. T., van Gisbergen, M. W., Even, A. J. G., Zegers, C. M. L., Das, M., Vegt, E., Wildberger, J. E., Mottaghy, F. M., Yaromina, A., Dubois, L. J., van Elmpt, W., De Ruysscher, D., & Lambin, P. (2020). Nitroglycerin as a radiosensitizer in non-small cell lung cancer: Results of a prospective imaging-based phase II trial. Clinical and Translational Radiation Oncology, 21, 49-55.
    • Jeukens, C. R. L. P. N., Kutterer, G., Kicken, P. J., Frantzen, M. J., van Engelshoven, J. M. A., Wildberger, J. E., & Kemerink, G. J. (2020). Gonad shielding in pelvic radiography: modern optimised X-ray systems might allow its discontinuation. Insights into Imaging, 11(1), [15].
    • Adriaans, B. P., Westenberg, J. J. M., van Cauteren, Y. J. M., Gerretsen, S., Elbaz, M. S. M., Bekkers, S. C. A. M., Veenstra, L. F., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2020). Clinical assessment of aortic valve stenosis: Comparison between 4D flow MRI and transthoracic echocardiography. Journal of Magnetic Resonance Imaging, 51(2), 472-480.
    • Eijsvoogel, N. G., Hendriks, B. M. F., Nelemans, P., Mihl, C., Willigers, J., Martens, B., Wildberger, J. E., & Das, M. (2020). Personalization of CM Injection Protocols in Coronary Computed Tomographic Angiography (People CT Trial). Contrast Media & Molecular Imaging, 2020, [5407936].
    • Tas, J., van Gassel, R. J. J., Heines, S. J. H., Mulder, M. M. G., Heijnen, N. F. L., Acampo-de Jong, M. J., Bels, J. L. M., Bennis, F. C., Koelmann, M., Groven, R. V. M., Donkers, M. A., van Rosmalen, F., Hermans, B. J. M., Meex, S. J. R., Mingels, A., Bekers, O., Savelkoul, P., Oude Lashof, A. M. L., Wildberger, J., ... van Bussel, B. C. T. (2020). Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort (MaastrICCht). BMJ Open, 10(9), [040175].
  • 2019
    • Neeter, L. M. F. H., Houben, I. P. L., Nelemans, P. J., Van Nijnatten, T. J. A., Pijnappel, R. M., Frotscher, C., Osinga-de Jong, M., Sanders, F., Van Dalen, T., Raat, H. P. J., Essers, B. A. B., Wildberger, J. E., Smidt, M. L., & Lobbes, M. B. (2019). Rapid Access to Contrast-Enhanced spectral mammogRaphy in women recalled from breast cancer screening: the RACER trial study design. Trials, 20(1), [759].
    • Adriaans, B. P., Wildberger, J. E., Westenberg, J. J. M., Lamb, H. J., & Schalla, S. (2019). Predictive imaging for thoracic aortic dissection and rupture: moving beyond diameters. European Radiology, 29(12), 6396-6404.
    • Boswijk, E., Franssen, R., Vijgen, G. H. E. J., Wierts, R., van Der Pol, J. A. J., Mingels, A. M. A., Cornips, E. M. J., Majoie, M. H. J. M., van Marken Lichtenbelt, W. D., Mottaghy, F. M., Wildberger, J. E., & Bucerius, J. (2019). Short-term discontinuation of vagal nerve stimulation alters F-18-FDG blood pool activity: an exploratory interventional study in epilepsy patients. EJNMMI Research, 9(1), [101].
    • Smulders, M. W., Kietselaer, B. L. J. H., Wildberger, J. E., Dagnelie, P. C., Brunner-La Rocca, H-P., Mingels, A. M. A., van Cauteren, Y. J. M., Theunissen, R. A. L. J., Post, M. J., Schalla, S., van Kuijk, S. M. J., Das, M., Kim, R. J., Crijns, H. J. G. M., & Bekkers, S. C. A. M. (2019). Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 74(20), 2466-2477.
    • Bruls, Y. M. H., de Ligt, M., Lindeboom, L., Phielix, E., Havekes, B., Schaart, G., Kornips, E., Wildberger, J. E., Hesselink, M. K. C., Muoio, D., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2019). Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial. EBioMedicine, 49, 318-330.
    • Lobbes, M. B., Hecker, J., Houben, I. P. L., Pluymakers, R., Jeukens, C., Laji, U. C., Gommers, S., Wildberger, J. E., & Nelemans, P. J. (2019). Evaluation of single-view contrast-enhanced mammography as novel reading strategy: a non-inferiority feasibility study. European Radiology, 29(11), 6211-6219.
    • Rengo, M., Dharampal, A., Lubbers, M., Kock, M., Wildberger, J. E., Das, M., Niezen, A., van Tilborg, F., Kofflard, M., Laghi, A., Krestin, G., & Nieman, K. (2019). Impact of iodine concentration and iodine delivery rate on contrast enhancement in coronary CT angiography: a randomized multicenter trial (CT-CON). European Radiology, 29(11), 6109-6118.
    • Nijssen, E. C., Nelemans, P. J., Wildberger, J. E., & AMACING Investigators (2019). Contrast-Associated Acute Kidney Injury. New England Journal of Medicine, 381(13), 1295-1296.
    • Houben, I. P. L., Vanwetswinkel, S., Kalia, M., Thywissen, T., Nelemans, P. J., Heuts, E. M., Smidt, M. L., Meyer-Baese, A., Wildberger, J. E., & Lobbes, M. B. (2019). Contrast-enhanced spectral mammography in the evaluation of breast suspicious calcifications: diagnostic accuracy and impact on surgical management. Acta Radiologica, 60(9), 1110-1117.
    • Nijssen, E. C., Nelemans, P. J., Rennenberg, R. J., Theunissen, R. A., van Ommen, V., & Wildberger, J. E. (2019). Prophylaxis in High-Risk Patients With eGFR <30 mL/min/1.73 m(2) Get the Balance Right. Investigative Radiology, 54(9), 580-588.
    • Peerlings, J., Paulis, L., Mitea, C., Bakers, F., Berbee, M., Wierts, R., Voo, S., Wildberger, J., Hoffmann, A., Lambin, P., & Mottaghy, F. (2019). Performing clinical F-18-FDG-PET/MRI of the mediastinum optimising a dedicated, patient-friendly protocol. Nuclear Medicine Communications, 40(8), 815-826.
    • Boswijk, E., Sanders, K. J. C., Broeders, E. P. M., de Ligt, M., Vijgen, G. H. E. J., Havekes, B., Mingels, A. M. A., Wierts, R., van Marken Lichtenbelt, W. D., Schrauwen, P., Mottaghy, F. M., Wildberger, J. E., & Bucerius, J. (2019). TSH suppression aggravates arterial inflammation an F-18-FDG PET study in thyroid carcinoma patients. European Journal of Nuclear Medicine and Molecular Imaging, 46(7), 1428-1438.
    • Jeukens, C. R. L. P. N., van Dijk, T., Berben, C., Wildberger, J. E., & Lobbes, M. B. I. (2019). Evaluation of pressure-controlled mammography compression paddles with respect to force-controlled compression paddles in clinical practice. European Radiology, 29(5), 2545-2552.
    • Sailer, A. M., Paulis, L., Vergoossen, L., Wildberger, J. E., & Jeukens, C. R. L. P. N. (2019). Optimizing Staff Dose in Fluoroscopy-Guided Interventions by Comparing Clinical Data with Phantom Experiments. Journal of Vascular and Interventional Radiology, 30(5), 701-708.
    • Crombag, G. A. J. C., van Hoof, R. H. M., Holtackers, R. J., Schreuder, F. H. B. M., Truijman, M. T. B., Schreuder, T. A. H. C. M. L., van Orshoven, N. P., Mess, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2019). Symptomatic Carotid Plaques Demonstrate Less Leaky Plaque Microvasculature Compared With the Contralateral Side: A Dynamic Contrast-Enhanced Magnetic Resonance Imaging Study. Journal of the American Heart Association, 8(8), [011832].
    • Bauwens, M., Pooters, I., Cobben, R., Visser, M., Schnerr, R., Mottaghy, F., Wildberger, J., & Wierts, R. (2019). A comparison of four radionuclide dose calibrators using various radionuclides and measurement geometries clinically used in nuclear medicine. Physica Medica: European journal of medical physics, 60, 14-21.
    • Nguyen, U. C., Cluitmans, M. J. M., Strik, M., Luermans, J. G., Gommers, S., Wildberger, J. E., Bekkers, S. C. A. M., Volders, P. G. A., Mihl, C., Prinzen, F. W., & Vernooy, K. (2019). Integration of cardiac magnetic resonance imaging, electrocardiographic imaging, and coronary venous computed tomography angiography for guidance of left ventricular lead positioning. EP Europace, 21(4), 626-635.
    • Kemerink, G. J., Kutterer, G., Kicken, P. J., van Engelshoven, J. M. A., Simon, K. J., & Wildberger, J. E. (2019). The skin dose of pelvic radiographs since 1896. Insights into Imaging, 10(1), [39].
    • Peerlings, J., Woodruff, H. C., Winfield, J. M., Ibrahim, A., Van Beers, B. E., Heerschap, A., Jackson, A., Wildberger, J. E., Mottaghy, F. M., DeSouza, N. M., & Lambin, P. (2019). Stability of radiomics features in apparent diffusion coefficient maps from a multi-centre test-retest trial. Scientific Reports, 9, 1-10. [4800].
    • Crombag, G. A. J. C., Schreuder, F. H. B. M., van Hoof, R. H. M., Truijman, M. T. B., Wijnen, N. J. A., Voo, S. A., Nelemans, P. J., Heeneman, S., Nederkoorn, P. J., Daemen, J-W. H., Daemen, M. J. A. P., Mess, W. H., Wildberger, J. E., van Oostenbrugge, R. J., & Kooi, M. E. (2019). Microvasculature and intraplaque hemorrhage in atherosclerotic carotid lesions: a cardiovascular magnetic resonance imaging study. Journal of Cardiovascular Magnetic Resonance, 21, [15].
    • Martens, B., Hendriks, B. M. F., Eijsvoogel, N. G., Wildberger, J. E., & Mihl, C. (2019). Individually Body Weight-Adapted Contrast Media Application in Computed Tomography Imaging of the Liver at 90 kVp. Investigative Radiology, 54(3), 177-182.
    • Hendriks, B. M. F., Schnerr, R. S., Milanese, G., Jeukens, C. R. L. P. N., Niesen, S., Eijsvoogel, N. G., Wildberger, J. E., & Das, M. (2019). Computed Tomography Pulmonary Angiography during Pregnancy: Radiation Dose of Commonly Used Protocols and the Effect of Scan Length Optimization. Korean Journal of Radiology, 20(2), 313-322.
    • Smith-Bindman, R., Wang, Y., Chu, P., Chung, R., Einstein, A. J., Balcombe, J., Cocker, M., Das, M., Delman, B. N., Flynn, M., Gould, R., Lee, R. K., Yellen-Nelson, T., Schindera, S., Seibert, A., Starkey, J., Suntharalingam, S., Wetter, A., Wildberger, J. E., & Miglioretti, D. L. (2019). International variation in radiation dose for computed tomography examinations: prospective cohort study. BMJ (e), 364, 1-12. [4931].
    • van Nijnatten, T. J. A., Smidt, M. L., Goorts, B., Samiei, S., Houben, I., Kok, E. M., Wildberger, J. E., Robben, S. G. F., & Lobbes, M. B. I. (2019). Can high school students help to improve breast radiologists in detecting missed breast cancer lesions on full-field digital mammography?Journal of Cancer, 10(3), 765-771.
    • Dudink, E., Florijn, B., Weijs, B., Duijs, J., Luermans, J., Peeters, F., Schurgers, L., Wildberger, J., Schotten, U., Bijkerk, R., Crijns, H. J., & van Zonneveld, A. J. (2019). Vascular Calcification and not Arrhythmia in Idiopathic Atrial Fibrillation Associates with Sex Differences in Diabetic Microvascular Injury miRNA Profiles. MicroRNA (Shāriqah, United Arab Emirates), 8(2), 127-134.
  • 2018
    • Wierts, R., Conti, M., Claessen, A. G. G., Herrmann, K., Kemerink, G. J., Binse, I., Wildberger, J. E., Mottaghy, F. M., Backes, W. H., & Jentzen, W. (2018). Impact of prompt gamma coincidence correction on absorbed dose estimation in differentiated thyroid cancer using I-124 PET/CT imaging. Nuclear Medicine Communications, 39(12), 1156-1164.
    • Morin, O., Vallieres, M., Jochems, A., Woodruff, H. C., Valdes, G., Braunstein, S. E., Wildberger, J. E., Villanueva-Meyer, J. E., Kearney, V., Yom, S. S., Solberg, T. D., & Lambin, P. (2018). A Deep Look Into the Future of Quantitative Imaging in Oncology: A Statement of Working Principles and Proposal for Change. International Journal of Radiation Oncology Biology Physics, 102(4), 1074-1082.
    • Horehledova, B., Mihl, C., Hendriks, B. M. F., Eijsvoogel, N. G., Vainer, J., Veenstra, L. F., Wildberger, J. E., & Das, M. (2018). Do CTA measurements of annular diameter, perimeter and area result in different TAVI prosthesis sizes?International Journal of Cardiovascular Imaging, 34(11), 1819-1829.
    • Adriaans, B. P., Heuts, S., Gerretsen, S., Cheriex, E. C., Vos, R., Natour, E., Maessen, J. G., Nia, P. S., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2018). Aortic elongation part I: the normal aortic ageing process. Heart, 104(21), 1772-1777.
    • Heuts, S., Adriaans, B. P., Gerretsen, S., Natour, E., Vos, R., Cheriex, E. C., Crijns, H. J. G. M., Wildberger, J. E., Maessen, J. G., Schalla, S., & Nia, P. S. (2018). Aortic elongation part II: the risk of acute type A aortic dissection. Heart, 104(21), 1778-1782.
    • Horehledova, B., Mihl, C., Milanese, G., Brans, R., Eijsvoogel, N. G., Hendriks, B. M. F., Wildberger, J. E., & Das, M. (2018). CT Angiography in the Lower Extremity Peripheral Artery Disease Feasibility of an Ultra-Low Volume Contrast Media Protocol. Cardiovascular and Interventional Radiology, 41(11), 1751-1764.