Remco Megens

Guest scientist

Dr Remco Megens combines his PI position at IPEK/LMU (Munich) with a position as visiting scientist at CARIM Department of Biomedical Engineering. His major research focus is the development and application of advanced microscopic methods and novel labeling strategies for atherosclerosis research. Advanced microscopic techniques have been extensively used to study various aspects of atherosclerosis in various experimental models. Application of two-photon laser scanning microscopy (TPLSM) for our research has a strong emphasis on its utilisation in the cardiovascular field. Novel TPLSM methods and labeling strategies have been developed that enable specific imaging of morphological and functional aspects of large arteries and leukocyte recruitment both in vivo and ex vivo. Besides imaging of samples at a microscopic resolution, Remco utilises and develops novel applications and staining strategies for multicolor superresolution (utilizing STED) to study atherosclerosis in 3D at a nanoscopic level.

Department of Biomedical engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2010
    • van Triest, H. J. W., Megens, R. T. A., van Assen, H. C., Romeny, B. M. T. H., & van Zandvoort, M. A. M. J. (2010). Arterial radius estimation from microscopic data using a new algorithm for circle parameter estimation. Journal of Biomedical Optics, 15(2), 8. https://doi.org/10.1117/1.3368679
    • Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. https://doi.org/10.1117/1.3281672