Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

2018
- van Tuijl, J. H., van Raak, E. P. M., van Oostenbrugge, R. J., Aldenkamp, A. P., & Rouhl, R. P. W. (2018). The occurrence of seizures after ischemic stroke does not influence long-term mortality; a 26-year follow-up study. Journal of Neurology, 265(8), 1780-1788. https://doi.org/10.1007/s00415-018-8907-7
- Mulder, M. J. H. L., Jansen, I. G. H., Goldhoorn, R.-J. B., Venema, E., Chalos, V., Compagne, K. C. J., Roozenbeek, B., Lingsma, H. F., Schonewille, W. J., van den Wijngaard, I. R., Boiten, J., Vos, J. A., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Registry Investigators (2018). Time to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results. Circulation, 138(3), 232-240. https://doi.org/10.1161/CIRCULATIONAHA.117.032600
- Autar, A. S. A., Hund, H. M., Ramlal, S. A., Hansen, D., Nijeholt, G. J. L. A., Emmer, B. J., de Maat, M. P. M., Dippel, D. W. J., van der Lugt, A., van Es, A. C. G. M., van Beusekom, H. M. M., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Staals, J., Postma - Jacobi, L., van Oostenbrugge, R. J., & van Zwam, W. (2018). High-Resolution Imaging of Interaction Between Thrombus and Stent-Retriever in Patients With Acute Ischemic Stroke. Journal of the American Heart Association, 7(13), Article 008563. https://doi.org/10.1161/JAHA.118.008563
- Loos, C. M. J., McHutchison, C., Cvoro, V., Makin, S. D. J., Staals, J., Chappell, F., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke. International journal of stroke, 13(5), 518-524. https://doi.org/10.1177/1747493017730780
- Boers, A. M. M., Sales Barros, R., Jansen, I. G. H., Berkhemer, O. A., Beenen, L. F. M., Menon, B. K., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Slump, C. H., Majoie, C. B. L. M., & Marquering, H. A. (2018). Value of Quantitative Collateral Scoring on CT Angiography in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 39(6), 1074-1082. https://doi.org/10.3174/ajnr.A5623
- Loos, C. M. J., Makin, S. D. J., Staals, J., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging. Stroke, 49(5), 1183–1188. https://doi.org/10.1161/STROKEAHA.117.020495
- Kimberly, W. T., Dutra, B. G., Boers, A. M. M., Alves, H. C. B. R., Berkhemer, O. A., van den Berg, L., Sheth, K. N., Roos, Y. B. W. E. M., van der Lugt, A., Beenen, L. F. M., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Marquering, H., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). Association of Reperfusion With Brain Edema in Patients With Acute Ischemic Stroke A Secondary Analysis of the MR CLEAN Trial. JAMA Neurology, 75(4), 453-461. https://doi.org/10.1001/jamaneurol.2017.5162
- Dijkland, S. A., Voormolen, D. C., Venema, E., Roozenbeek, B., Polinder, S., Haagsma, J. A., Nieboer, D., Chalos, V., Yoo, A. J., Schreuders, J., van der Lugt, A., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Zwam, W. H., van Oostenbrugge, R. J., Steyerberg, E. W., Dippel, D. W. J., Lingsma, H. F., & MR CLEAN Investigators (2018). Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials A Simulation Study. Stroke, 49(4), 965-971. https://doi.org/10.1161/STROKEAHA.117.020194
- Jansen, I. G. H., Mulder, M. J. H. L., Goldhoorn, R.-J. B., Emmer, B. J., van Es, A. C. G. M., Roozenbeek, B., Schonewille, W. J., van den Berg, R., Coutinho, J. M., Staals, J., Postma, A. A., Lycklama, G. J., Hofmeijer, J., Martens, J. M., den Hertog, H. M., Sturm, F. J. C., van der Worp, H. B., Lo, R. H., Heijboer, R. J. J., ... MR CLEAN Registry Investigators (2018). Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry). BMJ, 360, Article 949. https://doi.org/10.1136/bmj.k949
- Douven, E., Kohler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. R. J., & Aalten, P. (2018). Baseline Vascular Cognitive Impairment Predicts the Course of Apathetic Symptoms After Stroke: The CASPER Study. American Journal of Geriatric Psychiatry, 26(3), 291-300. https://doi.org/10.1016/j.jagp.2017.09.022
- Houben, R., Schreuder, F. H. B. M., Bekelaar, K. J., Claessens, D., van Oostenbrugge, R. J., & Staals, J. (2018). Predicting Prognosis of Intracerebral Hemorrhage (ICH): Performance of ICH Score Is Not Improved by Adding Oral Anticoagulant Use. Frontiers in Neurology, 9, Article 100. https://doi.org/10.3389/fneur.2018.00100
- Jansen, I. G. H., van Vuuren, A. B., van Zwam, W. H., van den Wijngaard, I. R., Berkhemer, O. A., Lingsma, H. F., Slump, C. H., van Oostenbrugge, R. J., Treurniet, K. M., Dippel, D. W. J., van Walderveen, M. A. A., van der Lugt, A., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., van den Berg, R., & MR CLEAN Trial Investigators (2018). Absence of Cortical Vein Opacification Is Associated with Lack of Intra-arterial Therapy Benefit in Stroke. Radiology, 286(2), 643-650. https://doi.org/10.1148/radiol.2017162445
- Treurniet, K. M., Berkhemer, O. A., Immink, R. V., Lingsma, H. F., Ward-van der Stam, V. M. C., Hollmann, M. W., Vuyk, J., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Dippel, D. W. J., Coutinho, J. M., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). A decrease in blood pressure is associated with unfavorable outcome in patients undergoing thrombectomy under general anesthesia. Journal of Neurointerventional Surgery, 10(2), 107-111. https://doi.org/10.1136/neurintsurg-2017-012988
- Alves, H. C., Treurniet, K. M., Dutra, B. G., Jansen, I. G. H., Boers, A. M. M., Santos, E. M. M., Berkhemer, O. A., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Roos, Y. B. W. E. M., Yoo, A. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2018). Associations Between Collateral Status and Thrombus Characteristics and Their Impact in Anterior Circulation Stroke. Stroke, 49(2), 391-396. https://doi.org/10.1161/STROKEAHA.117.019509
- Uiterwijk, R., Staals, J., Huijts, M., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2018). Framingham Stroke Risk Profile is related to cerebral small vessel disease progression and lower cognitive performance in patients with hypertension. Journal of Clinical Hypertension, 20(2), 240-245. https://doi.org/10.1111/jch.13175
- Wong, S. M., Backes, W. H., Zhang, C. E., Staals, J., van Oostenbrugge, R. J., Jeukens, C. R. L. P. N., & Jansen, J. F. A. (2018). On the Reproducibility of Inversion Recovery Intravoxel Incoherent Motion Imaging in Cerebrovascular Disease. American Journal of Neuroradiology, 39(2), 226-231. https://doi.org/10.3174/ajnr.A5474
- Campbell, B. C. V., van Zwam, W. H., Goyal, M., Menon, B. K., Dippel, D. W. J., Demchuk, A. M., Bracard, S., White, P., Davalos, A., Majoie, C. B. L. M., van der Lugt, A., Ford, G. A., de la Ossa, N., Kelly, M., Bourcier, R., Donnan, G. A., Roos, Y. B. W. E. M., Bang, O. Y., Nogueira, R. G., ... HERMES Collaboration (2018). Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data. Lancet Neurology, 17(1), 47-53. https://doi.org/10.1016/S1474-4422(17)30407-6
2017
- Schnerr, R. S., Jansen, J. F. A., Uludag, K., Hofman, P. A. M., Wildberger, J. E., van Oostenbrugge, R. J., & Backes, W. H. (2017). Pulsatility of Lenticulostriate Arteries Assessed by 7 Tesla Flow MRI: Measurement, Reproducibility, and Applicability to Aging Effect. Frontiers in physiology, 8, Article 961. https://doi.org/10.3389/fphys.2017.00961
- Boers, A. M. M., Jansen, I. G. H., Berkhemer, O. A., Yoo, A. J., Lingsma, H. F., Slump, C. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Collateral status and tissue outcome after intra-arterial therapy for patients with acute ischemic stroke. Journal of Cerebral Blood Flow and Metabolism, 37(11), 3589-3598. https://doi.org/10.1177/0271678X16678874
- Compagne, K. C. J., van Es, A. C. G. M., Berkhemer, O. A., Borst, J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., Marquering, H. A., Dippel, D. W. J., van der Lugt, A., Emmer, B. J., & MR CLEAN Trial Investigators (2017). Prevalence of Carotid Web in Patients with Acute Intracranial Stroke Due to Intracranial Large Vessel Occlusion. Radiology, 286(3), 1000-1007. https://doi.org/10.1148/radiol.2017170094
- Heshmatollah, A., Fransen, P. S. S., Berkhemer, O. A., Beumer, D., van der Lugt, A., Majoie, C. B. L. M., Oostenbrugge, R. J., van Zwam, W. H., Koudstaal, P. J., Roos, Y. B. W. E. M., Dippel, D. W. J., & MR CLEAN Investigators (2017). Endovascular thrombectomy in patients with acute ischaemic stroke and atrial fibrillation: a MR CLEAN subgroup analysis. Eurointervention, 13(8), 996-1002. https://doi.org/10.4244/EIJ-D-16-00905
- Schreuders, J., van den Berg, L. A., Fransen, P. S. S., Berkhemer, O. A., Beumer, D., Lingsma, H. F., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., de Kort, P. L. M., Roos, Y. B. W. E. M., Dippel, D. W. J., & MR CLEAN Investigators (2017). Quality of life after intra-arterial treatment for acute ischemic stroke in the MR CLEAN trialUpdate. International journal of stroke, 12(7), 708-712. https://doi.org/10.1177/1747493017706244
- van Hoof, R. H. M., Voo, S. A., Sluimer, J. C., Wijnen, N. J. A., Hermeling, E., Schreuder, F. H. B. M., Truijman, M. T. B., Cleutjens, J. P. M., Daemen, M. J. A. P., Daemen, J.-W. H., van Oostenbrugge, R. J., Mess, W. H., Wildberger, J. E., Heeneman, S., & Kooi, M. E. (2017). Vessel Wall and Adventitial DCE-MRI Parameters Demonstrate Similar Correlations With Carotid Plaque Microvasculature on Histology. Journal of Magnetic Resonance Imaging, 46(4), 1053-1059. https://doi.org/10.1002/jmri.25648
- Hauer, A. J., Pulit, S. L., van den Berg, L. H., de Bakker, P. I. W., Veldink, J. H., Dutch Parelsnoer Inst-Cerebrovasc, van Oostenbrugge, R. J., & Ruigrok, Y. M. (2017). A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study. Scientific Reports, 7, Article 12175. https://doi.org/10.1038/s41598-017-07404-4
- Deckers, K., Schievink, S. H. J., Rodriquez, M. M. F., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J., & Kohler, S. (2017). Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis. PLOS ONE, 12(9), Article e0184244. https://doi.org/10.1371/journal.pone.0184244
- Ernst, M., Boers, A. M. M., Aigner, A., Berkhemer, O. A., Yoo, A. J., Roos, Y. B., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Fiehler, J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Association of Computed Tomography Ischemic Lesion Location With Functional Outcome in Acute Large Vessel Occlusion Ischemic Stroke. Stroke, 48(9), 2426-2433. https://doi.org/10.1161/STROKEAHA.117.017513
- Claessens, D., Bekelaar, K., Schreuder, F. H. B. M., de Greef, B. T. A., Vlooswijk, M. C. G., Staals, J., van Oostenbrugge, R. J., & Rouhl, R. P. W. (2017). Mortality after primary intracerebral hemorrhage in relation to post-stroke seizures. Journal of Neurology, 264(9), 1885-1891. https://doi.org/10.1007/s00415-017-8573-1
- Borst, J., Berkhemer, O. A., Santos, E. M. M., Yoo, A. J., den Blanken, M., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2017). Value of Thrombus CT Characteristics in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 38(9), 1758-1764. https://doi.org/10.3174/ajnr.A5331
- Venema, E., Boodt, N., Berkhemer, O. A., Rood, P. P. M., van Zwam, W. H., van Oostenbrugge, R. J., van der Lugt, A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Lingsma, H. F., Dippel, D. W. J., & MR CLEAN Investigators (2017). Workflow and factors associated with delay in the delivery of intra-arterial treatment for acute ischemic stroke in the MR CLEAN trial. Journal of Neurointerventional Surgery, 10(5), 424-U19. https://doi.org/10.1136/neurintsurg-2017-013198
- Mulder, M. J. H. L., Ergezen, S., Lingsma, H. F., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Nijeholt, G. L. A., Emmer, B. J., van der Worp, H. B., Nederkoorn, P. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & Multicenter Randomized Clinical Tr (2017). Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands). Stroke, 48(7), 1869-1876. https://doi.org/10.1161/STROKEAHA.116.016225
- Wong, S. M., Jansen, J. F. A., Zhang, C. E., Staals, J., Hofman, P. A. M., van Oostenbrugge, R. J., Jeukens, C. R. L. P. N., & Backes, W. H. (2017). Measuring subtle leakage of the blood-brain barrier in cerebrovascular disease with DCE-MRI: Test-retest reproducibility and its influencing factors. Journal of Magnetic Resonance Imaging, 46(1), 159-166. https://doi.org/10.1002/jmri.25540
- Berkhemer, O. A., Borst, J., Kappelhof, M., Yoo, A. J., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Schonewille, W. J., Nederkoorn, P. J., Wermer, M. J. H., Marquering, H. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., van Zwam, W. H., Majoie, C. B. L. M., Emmer, B. J., van der Lugt, A., & MR CLEAN Investigators (2017). Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke in MR CLEAN. Annals of Internal Medicine, 166(12), 867-875. https://doi.org/10.7326/M16-1536
- Beumer, D., van Boxtel, T. H., Schipperen, S., van Zwam, W. H., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Schonewille, W. J., Vos, J. A., van der Lugt, A., Roos, Y. B., Majoie, C. B., van Oostenbrugge, R. J., Dippel, D. W. J., & MR CLEAN Pretrial Investigators (2017). The relationship between interventionists' experience and clinical and radiological outcome in intra-arterial treatment for acute ischemic stroke. A MR CLEAN pretrial survey. Journal of the Neurological Sciences, 377, 97-101. https://doi.org/10.1016/j.jns.2017.04.002
- Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Lingsma, H. F., den Hertog, H. M., Staals, J., Jenniskens, S. F. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Investigators (2017). Does prior antiplatelet treatment improve functional outcome after intra-arterial treatment for acute ischemic stroke?International journal of stroke, 12(4), 368-376. https://doi.org/10.1177/1747493016677842
- Uiterwijk, R., Staals, J., Huijts, M., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2017). MRI progression of cerebral small vessel disease and cognitive decline in patients with hypertension. Journal of Hypertension, 35(6), 1263-1270. https://doi.org/10.1097/HJH.0000000000001294
- Venema, E., Mulder, M. J. H. L., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Emmer, B. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials. BMJ, 357, Article j1710. https://doi.org/10.1136/bmj.j1710
- Osei, E., den Hertog, H. M., Berkhemer, O. A., Fransen, P. S. S., Roos, Y. B. W. E. M., Beumer, D., van Oostenbrugge, R. J., Schonewille, W. J., Boiten, J., Zandbergen, A. A. M., Koudstaal, P. J., MR CLEAN Investigators, van Zwam, W., & Dippel, D. W. J. (2017). Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke. Stroke, 48(5), 1299-1305. https://doi.org/10.1161/STROKEAHA.116.016071
- Hauer, A. J., Ruigrok, Y. M., Algra, A., van Dijk, E. J., Koudstaal, P. J., Luijckx, G.-J., Nederkoorn, P. J., van Oostenbrugge, R. J., Visser, M. C., Wermer, M. J., Kappelle, L. J., Klijn, C. J. M., & Dutch Parelsnoer Inst-Cerebrovasc (2017). Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype. Journal of the American Heart Association, 6(5), Article 005090. https://doi.org/10.1161/JAHA.116.005090
- Bucker, A., Boers, A. M., Bot, J. C. J., Berkhemer, O. A., Lingsma, H. F., Yoo, A. J., Van Zwam, W. H., Van Oostenbrugge, R. J., Van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Marquering, H. A., MR CLEAN Trial Investigators, & Multictr Randomized Clinical Trial (2017). Associations of Ischemic Lesion Volume With Functional Outcome in Patients With Acute Ischemic Stroke 24-Hour Versus 1-Week Imaging. Stroke, 48(5), 1233-1240. https://doi.org/10.1161/STROKEAHA.116.015156
- Boers, A. M. M., Berkhemer, O. A., Slump, C. H., van Zwam, W. H., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., Yoo, A. J., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Topographic distribution of cerebral infarct probability in patients with acute ischemic stroke: mapping of intra-arterial treatment effect. Journal of Neurointerventional Surgery, 9(5), 431-436. https://doi.org/10.1136/neurintsurg-2016-012387
- van den Berg, L. A., Dijkgraaf, M. G. W., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H. F., Majoie, C. B. L. M., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B. W. E. M., & MR CLEAN Investigators (2017). Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke. New England Journal of Medicine, 376(14), 1341-1349. https://doi.org/10.1056/NEJMoa1612136
- van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J., Steinbusch, H. W. M., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. JFA. (2017). Cerebral pathology and cognition in diabetes: the merits of multiparametric neuroimaging. Frontiers in Neuroscience, 11, Article 188. https://doi.org/10.3389/fnins.2017.00188
- Zhang, C. E., Wong, S. M., Uiterwijk, R., Staals, J., Backes, W. H., Hoff, E. I., Schreuder, T., Jeukens, C. R. L. P. N., Jansen, J. F. A., & van Oostenbrugge, R. J. (2017). Intravoxel Incoherent Motion Imaging in Small Vessel Disease Microstructural Integrity and Microvascular Perfusion Related to Cognition. Stroke, 48(3), 658-663. https://doi.org/10.1161/STROKEAHA.116.015084
- Mulder, M. J. H. L., Venema, E., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Towards personalised intra- arterial treatment of patients with acute ischaemic stroke: a study protocol for development and validation of a clinical decision aid. BMJ Open, 7(3), Article 013699. https://doi.org/10.1136/bmjopen-2016-013699
- Wagemans, B. A. J. M., van Zwam, W. H., Nelemans, P. J., van Oostenbrugge, R. J., & Postma, A. A. (2017). 4D-CTA improves diagnostic certainty and accuracy in the detection of proximal intracranial anterior circulation occlusion in acute ischemic stroke. PLOS ONE, 12(2), Article 0172356. https://doi.org/10.1371/journal.pone.0172356
- Zhang, C. E., Wong, S. M., van de Haar, H. J., Staals, J., Jansen, J. F. A., Jeukens, C. R. L. P. N., Hofman, P. A. M., van Oostenbrugge, R. J., & Backes, W. H. (2017). Blood-brain barrier leakage is more widespread in patients with cerebral small vessel disease. Neurology, 88(5), 426-432. https://doi.org/10.1212/WNL.0000000000003556
- van Hoof, R. H. M., Schreuder, F. H. B. M., Nelemans, P., Truijman, M. T. B., van Orshoven, N. P., Schreuder, T. H., Mess, W. H., Heeneman, S., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2017). Ischemic Stroke Patients Demonstrate Increased Carotid Plaque Microvasculature Compared to (Ocular) Transient Ischemic Attack Patients. Cerebrovascular Diseases, 44(5-6), 297-303. https://doi.org/10.1159/000481146
- Wong, S. M., Zhang, C. E., van Bussel, F. C. G., Staals, J., Jeukens, C. R. L. P. N., Hofman, P. A. M., van Oostenbrugge, R. J., Backes, W. H., & Jansen, J. F. A. (2017). Simultaneous investigation of microvasculature and parenchyma in cerebral small vessel disease using intravoxel incoherent motion imaging. NeuroImage: Clinical, 14, 216-221. https://doi.org/10.1016/j.nicl.2017.01.017
- Douven, E., Kohler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. RJ., & Aalten, P. (2017). Temporal Associations between Fatigue, Depression, and Apathy after Stroke: Results of the Cognition and Affect after Stroke, a Prospective Evaluation of Risks Study. Cerebrovascular Diseases, 44(5-6), 330-337. https://doi.org/10.1159/000481577
- Hooghiemstra, A. M., Bertens, A. S., Leeuwis, A. E., Bron, E. E., Bots, M. L., Brunner-La Rocca, H.-P., de Craen, A. J. M., van der Geest, R. J., Greving, J. P., Kappelle, L. J., Niessen, W. J., van Oostenbrugge, R. J., van Osch, M. J. P., de Roos, A., van Rossum, A. C., Biessels, G. J., van Buchem, M. A., Daemen, M. J. A. P., van der Flier, W. M., & Heart-Brain Connection Consortium (2017). The Missing Link in the Pathophysiology of Vascular Cognitive Impairment: Design of the Heart-Brain Study. Cerebrovascular Diseases Extra, 7(3), 140-152. https://doi.org/10.1159/000480738

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Longer and better lives for patients with atrial fibrillation

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