Simon Schalla

Assistant Professor

Dr Simon Schalla is involved in clinical reading, teaching and research in cardiovascular magnetic resonance imaging since 1997. Focus of his research is imaging of cardiovascular disease using echocardiography, computed tomography and magnetic resonance imaging.

Postgraduate medical training
1995 - 2006 1) University Hospital Ulm, 2) University Hospital Tübingen, 3) German Heart Institute Berlin/Charite, Humboldt University
2001 - 2003 Fellow of the German Cardiac Society at the University of California San Francisco, Cardiac MR Imaging

Positions
Since December 2003 Maastricht University Medical Center, Department of Cardiology. Since 2014 also a shared appointment at the Departments of Cardiology and Radiology, Maastricht University Medical Center

Doctoral thesis
Biologisch-physikalische Charakterisierung der Strahlenqualität schneller Neutronen bei isozentrischer Bewegungsbestrahlung, Heidelberg, 26-10-1994

PhD-thesis
Cardiovascular magnetic resonance: A key to imaging cardiac function, Maastricht, 06-07-2015

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T: +31(0)43 387 70 93

  • 2020
    • Gulpen, A. J. W., van Dijk, J. K., Damen, N. L., ten Cate, H., Schalla, S., & Ten Cate-Hoek, A. J. (2020). Organisation of care for patients using direct oral anticoagulants. Netherlands Heart Journal, 28(9), 452-456. https://doi.org/10.1007/s12471-020-01436-8
    • Heuts, S., Adriaans, B. P., Rylski, B., Mihl, C., Bekkers, S. C. A. M., Olsthoorn, J. R., Natour, E., Bouman, H., Berezowski, M., Kosiorowska, K., Crijns, H. J. G. M., Maessen, J. G., Wildberger, J., Schalla, S., & Nia, P. S. (2020). Evaluating the diagnostic accuracy of maximal aortic diameter, length and volume for prediction of aortic dissection. Heart, 106(12), 892-897. https://doi.org/10.1136/heartjnl-2019-316251
    • Adriaans, B. P., Westenberg, J. J. M., van Cauteren, Y. J. M., Gerretsen, S., Elbaz, M. S. M., Bekkers, S. C. A. M., Veenstra, L. F., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2020). Clinical assessment of aortic valve stenosis: Comparison between 4D flow MRI and transthoracic echocardiography. Journal of Magnetic Resonance Imaging, 51(2), 472-480. https://doi.org/10.1002/jmri.26847
  • 2019
    • Adriaans, B. P., Wildberger, J. E., Westenberg, J. J. M., Lamb, H. J., & Schalla, S. (2019). Predictive imaging for thoracic aortic dissection and rupture: moving beyond diameters. European Radiology, 29(12), 6396-6404. https://doi.org/10.1007/s00330-019-06320-7
    • Smulders, M. W., Kietselaer, B. L. J. H., Wildberger, J. E., Dagnelie, P. C., Brunner-La Rocca, H-P., Mingels, A. M. A., van Cauteren, Y. J. M., Theunissen, R. A. L. J., Post, M. J., Schalla, S., van Kuijk, S. M. J., Das, M., Kim, R. J., Crijns, H. J. G. M., & Bekkers, S. C. A. M. (2019). Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 74(20), 2466-2477. https://doi.org/10.1016/j.jacc.2019.09.027
    • Habib, G., Erba, P. A., Iung, B., Donal, E., Cosyns, B., Laroche, C., Popescu, B. A., Prendergast, B., Tornos, P., Sadeghpour, A., Oliver, L., Vaskelyte, J-J., Sow, R., Axler, O., Maggioni, A. P., Lancellotti, P., Granada, Mahia, M., Ressi, S., ... EURO-ENDO Investigators (2019). Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European infective endocarditis) registry: a prospective cohort study. European Heart Journal, 40(39), 3222-+. https://doi.org/10.1093/eurheartj/ehz620
    • Habib, G., Lancellotti, P., Erba, P-A., Sadeghpour, A., Meshaal, M., Sambola, A., Furnaz, S., Citro, R., Ternacle, J., Donal, E., Cosyns, B., Popescu, B., Iung, B., Prendergast, B., Laroche, C., Tornos, P., Pazdernik, M., Maggioni, A., Gale, C. P., ... EURO-ENDO Investigators (2019). The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry. European heart journal. Quality of care & clinical outcomes, 5(3), 202-207. https://doi.org/10.1093/ehjqcco/qcz018
    • Gulpen, A. J. W., ten Cate, H., Henskens, Y. M. C., van Oerle, R., Wetzels, R., Schalla, S., Crijns, H. J., & ten Cate-Hoek, A. J. (2019). The daily practice of direct oral anticoagulant use in patients with atrial fibrillation; an observational cohort study. PLOS ONE, 14(6), [0217302]. https://doi.org/10.1371/journal.pone.0217302
    • van Mourik, M. J. W., Zaar, D. V. J., Smulders, M. W., Heijman, J., Lumens, J., Dokter, J. E., Passos, V. L., Schalla, S., Knackstedt, C., Schummers, G., Gjesdal, O., Edvardsen, T., & Bekkers, S. C. A. M. (2019). Adding Speckle-Tracking Echocardiography to Visual Assessment of Systolic Wall Motion Abnormalities Improves the Detection of Myocardial Infarction. Journal of the American Society of Echocardiography, 32(1), 65-73. https://doi.org/10.1016/j.echo.2018.09.007
  • 2018
    • Adriaans, B. P., Heuts, S., Gerretsen, S., Cheriex, E. C., Vos, R., Natour, E., Maessen, J. G., Nia, P. S., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2018). Aortic elongation part I: the normal aortic ageing process. Heart, 104(21), 1772-1777. https://doi.org/10.1136/heartjnl-2017-312866
    • Heuts, S., Adriaans, B. P., Gerretsen, S., Natour, E., Vos, R., Cheriex, E. C., Crijns, H. J. G. M., Wildberger, J. E., Maessen, J. G., Schalla, S., & Nia, P. S. (2018). Aortic elongation part II: the risk of acute type A aortic dissection. Heart, 104(21), 1778-1782. https://doi.org/10.1136/heartjnl-2017-312867
    • van Riel, S. A. J. M., Balthasar, A. J. R., Schalla, S. M., Siemonsma, M. A., & van Mook, W. N. K. A. (2018). Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine. Netherlands Journal of Critical Care, 26(5), 194-197. https://www.njcc.nl/sites/nvic.nl/files/pdf/case-report1_12.pdf
    • Peeters, F. E. C. M., van Mourik, M. J. W., Meex, S. J. R., Bucerius, J., Schalla, S. M., Gerretsen, S. C., Mihl, C., Dweck, M. R., Schurgers, L. J., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using F-18-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients, 10(4), [386]. https://doi.org/10.3390/nu10040386
    • Verdonschot, J. A. J., Hazebroek, M. R., Derks, K. W. J., Aizpurua, A. B., Merken, J. J., Wang, P., Bierau, J., van den Wijngaard, A., Schalla, S. M., Hamid, M. A. A., van Bilsen, M., van Empel, V. P. M., Knackstedt, C., Brunner-La Rocca, H-P., Brunner, H. G., Krapels, I. P. C., & Heymans, S. R. B. (2018). Titin cardiomyopathy leads to altered mitochondrial energetics, increased fibrosis and long-termlife-threatening arrhythmias. European Heart Journal, 39(10), 864-873. https://doi.org/10.1093/eurheartj/ehx808
    • Henskens, Y. M. C., Gulpen, A. J. W., van Oerle, R., Wetzels, R., Verhezen, P., Spronk, H., Schalla, S., Crijns, H. J., ten Cate, H., & ten Cate-Hoek, A. (2018). Detecting clinically relevant rivaroxaban or dabigatran levels by routine coagulation tests or thromboelastography in a cohort of patients with atrial fibrillation. Thrombosis Journal, 16, [3]. https://doi.org/10.1186/s12959-017-0160-2
  • 2017
    • Jaarsma, C., Vink, H., van Haare, J., Bekkers, S. C. A. M., van Rooijen, B. D., Backes, W. H., Wildberger, J. E., Crijns, H. J., van Teeffelen, J., & Schalla, S. (2017). Non-invasive assessment of microvascular dysfunction in patients with microvascular angina. International Journal of Cardiology, 248, 433-439. https://doi.org/10.1016/j.ijcard.2017.05.010
    • Smulders, M. W., Jaarsma, C., Nelemans, P. J., Bekkers, S. C. A. M., Bucerius, J., Leiner, T., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2017). Comparison of the prognostic value of negative non-invasive cardiac investigations in patients with suspected or known coronary artery disease-ameta-analysis. European Heart Journal Cardiovascular Imaging, 18(9), 980-987. https://doi.org/10.1093/ehjci/jex014
  • 2016
    • Smulders, M. W., Kietselaer, B. L. J. H., Schalla, S., Bucerius, J., Jaarsma, C., van Dieijen-Visser, M. P., Mingels, A. M. A., Brunner-La Rocca, H., Post, M., Das, M., Crijns, H. J. G. M., Wildberger, J. E., & Bekkers, B. (2016). Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging?American Heart Journal, 177, 102-111. https://doi.org/10.1016/j.ahj.2016.03.025
    • Vainer, J., Habets, J. H. M., Schalla, S., Lousberg, A. H. P., de Pont, C. D. J. M., Vöö, S., Brans, B. T., Hoorntje, J. C. A., & Waltenberger, J. (2016). Cardiac shockwave therapy in patients with chronic refractory angina pectoris. Netherlands Heart Journal, 24(5), 343-349. https://doi.org/10.1007/s12471-016-0821-y
  • 2015
    • Hazebroek, M. R., Kemna, M. J., Schalla, S., Sanders-van Wijk, S., Gerretsen, S. C., Dennert, R., Merken, J., Kuznetsova, T., Staessen, J. A., Brunner-La Rocca, H. P., van Paassen, P., Tervaert, J. W. C., & Heymans, S. (2015). Prevalence and prognostic relevance of cardiac involvement in ANCA-associated vasculitis: Eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis. International Journal of Cardiology, 199, 170-179. https://doi.org/10.1016/j.ijcard.2015.06.087
  • 2014
    • El Aidi, H., Adams, A., Moons, K. G. M., Den Ruijter, H. M., Mali, W. P. T. M., Doevendans, P. A., Nagel, E., Schalla, S., Bots, M. L., & Leiner, T. (2014). Cardiac Magnetic Resonance Imaging Findings and the Risk of Cardiovascular Events in Patients With Recent Myocardial Infarction or Suspected or Known Coronary Artery Disease. Journal of the American College of Cardiology, 63(11), 1031-1045. https://doi.org/10.1016/j.jacc.2013.11.048
    • van Dongen, M., van Kraaij, D., Schalla, S., Brunner-La Rocca, H., & Driessen, R. (2014). Severe mitral regurgitation caused by eosinophilic endocarditis. Journal of Cardiology Cases, 10(3). https://doi.org/10.1016/j.jccase.2014.05.012
  • 2013
    • Jaarsma, C., Bekkers, B., Haidari, Z., Smulders, M. W., Nelemans, P. J., Gorgels, A. P., Crijns, H. J., Wildberger, J. E., & Schalla, S. (2013). Comparison of Different Electrocardiographic Scoring Systems for Detection of any Previous Myocardial Infarction as Assessed With Cardiovascular Magnetic Resonance Imaging. American Journal of Cardiology, 112(8), 1069-1074. https://doi.org/10.1016/j.amjcard.2013.05.048
    • Jaarsma, C., Schalla, S., Cheriex, E. C., Smulders, M. W., van Dongen, I., Nelemans, P. J., Gorgels, A. P. M., Wildberger, J. E., Crijns, H. J. G. M., & Bekkers, B. (2013). Incremental value of cardiovascular magnetic resonance over echocardiography in the detection of acute and chronic myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 15, [5]. https://doi.org/10.1186/1532-429X-15-5
  • 2012
    • Hermans, M. C. E., Faber, C. G., Bekkers, S. C. A. M., de Die-Smulders, C. E. M., Gerrits, M. M., Merkies, I. S. J., Snoep, G., Pinto, Y. M., & Schalla, S. (2012). Structural and functional cardiac changes in myotonic dystrophy type 1: a cardiovascular magnetic resonance study. Journal of Cardiovascular Magnetic Resonance, 14, 46. https://doi.org/10.1186/1532-429X-14-48
    • Jaarsma, C., Leiner, T., Bekkers, S. C., Crijns, H. J., Wildberger, J. E., Nagel, E., Nelemans, P. J., & Schalla, S. (2012). Diagnostic Performance of Noninvasive Myocardial Perfusion Imaging Using Single-Photon Emission Computed Tomography, Cardiac Magnetic Resonance, and Positron Emission Tomography Imaging for the Detection of Obstructive Coronary Artery Disease A Meta-Analysis. Journal of the American College of Cardiology, 59(19), 1719-1728. https://doi.org/10.1016/j.jacc.2011.12.040
    • van der Weg, K., Bekkers, S. C. A. M., Winkens, B., Lemmert, M. E., Schalla, S., Crijns, H. J. G. M., Waltenberger, J., & Gorgels, A. P. M. (2012). Evaluation of the electrocardiogram in identifying and quantifying lateral involvement in nonanterior wall infarction using cardiovascular magnetic resonance imaging. Journal of Electrocardiology, 45(5), 478-484. https://doi.org/10.1016/j.jelectrocard.2012.04.008
  • 2011
    • van Rijsingen, I. A. W., Bekkers, S. C. A. M., Schalla, S., Hermans-van Ast, J. F., Snoep, G., Alzand, B. S. N., Arens, Y. H. J. M., van den Wijngaard, A., Crijns, H. J. G. M., & Pinto, Y. M. (2011). Exercise related ventricular arrhythmias are related to cardiac fibrosis in hypertrophic cardiomyopathy mutation carriers. Netherlands Heart Journal, 19(4), 168-174. https://doi.org/10.1007/s12471-011-0090-8
    • Bekkers, S. C., Lemmert, M. E., Passos, V. L., Mihl, C., Schalla, S., Wildberger, J. E., Waltenberger, J., & Gorgels, A. P. M. (2011). The relationships between cardiovascular magnetic resonance imaging variables of acute myocardial infarction and both left ventricular dysfunction and immediate postreperfusion ST segment recovery. Journal of Electrocardiology, 44(5), 561-567. https://doi.org/10.1016/j.jelectrocard.2011.07.006
  • 2010
    • Verjans, J., Wolters, S., Laufer, W., Schellings, M., Lax, M., Lovhaug, D., Boersma, H., Kemerink, G. J., Schalla, S., Gordon, P., Teule, J., Narula, J., & Hofstra, L. (2010). Early molecular imaging of interstitial changes in patients after myocardial infarction: Comparison with delayed contrast-enhanced magnetic resonance imaging. Journal of Nuclear Cardiology, 17(6), 1065-1072. https://doi.org/10.1007/s12350-010-9268-5
    • Bekkers, S. C. A. M., Smulders, M. W., Passos, V. L., Leiner, T., Waltenberger, J., Gorgels, A. P. M., & Schalla, S. (2010). Clinical implications of microvascular obstruction and intramyocardial haemorrhage in acute myocardial infarction using cardiovascular magnetic resonance imaging. European Radiology, 20(11), 2572-2578. https://doi.org/10.1007/s00330-010-1849-9
    • Schalla, S., Bekkers, S. C., Dennert, R., van Suylen, R. J., Waltenberger, J., Leiner, T., Wildberger, J., Crijns, H. J., & Heymans, S. (2010). Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. European journal of heart failure, 12(3), 227-231. https://doi.org/10.1093/eurjhf/hfq004
    • Dennert, R. M., van Paassen, P., Schalla, S., Kuznetsova, T., Alzand, B. S. N., Staessen, J. A., Velthuis, S., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2010). Cardiac Involvement in Churg-Strauss Syndrome. Arthritis & Rheumatism, 62(2), 627-634. https://doi.org/10.1002/art.27263
    • Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516
    • Dennert, R., Velthuis, S., Westermann, D., Donker, D. W., Schalla, S., van Suylen, R-J., & Heymans, S. (2010). Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy. Antiviral Therapy, 15(4), 681-685. https://doi.org/10.3851/IMP1563