Steven Meex

Clinical Chemist

Dr Steven Meex is a clinical chemist and head of the unit general clinical chemistry and hematology of the Central Diagnostic Laboratory of Maastrcith UMC+. He graduated in 2002 with specialisation in both molecular biology and epidemiology at Maastricht University. During his PhD at the Department of Internal Medicine in Maastricht, he worked on the cardiovascular genetics including type 2 diabetes and hyperlipidemia. Subsequently, he worked as acardiovascular research fellow at San Diego State University (2006) and at New York University (2008-2009).

His current research is focussed on cardiac markers,combining epidemiology, cell biology, analytical chemistry, and patient studies to improve the diagnosis and treatment of cardiovascular diseases.

Central Diagnostic Laboratory
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 5.E2.002
T: +31(0)43 387 47 09

  • 2014
    • Klinkenberg, L. J. J., van Dijk, J. W., Tan, F. E. S., van Loon, L. J. C., van Dieijen-Visser, M. P., & Meex, S. J. R. (2014). Circulating Cardiac Troponin T Exhibits a Diurnal Rhythm. Journal of the American College of Cardiology, 63(17), 1788-1795. https://doi.org/10.1016/j.jacc.2014.01.040
    • Marsch, E., Theelen, T. L., Demandt, J. A., Jeurissen, M., van Gink, M., Verjans, R., Janssen, A., Cleutjens, J. P., Meex, S. J., Donners, M. M., Haenen, G., Schalkwijk, C. G., Dubois, L. J., Lambin, P., Mallat, Z., Gijbels, M. J., Heemskerk, J. W., Fisher, E. A., Biessen, E. A., ... Sluimer, J. C. (2014). Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis. Arteriosclerosis Thrombosis and Vascular Biology, 34(12), 2545-2553. https://doi.org/10.1161/ATVBAHA.114.304023
  • 2012
    • Klinkenberg, L. J., Res, P. T., van Loon, L. J. C., van Dieijen-Visser, M. P., & Meex, S. J. R. (2012). Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk?International Journal of Cardiology, 158(1), 129-131. https://doi.org/10.1016/j.ijcard.2012.04.050
    • Cardinaels, E. P., Mingels, A. M., Jacobs, L. H., Meex, S. J., Bekers, O., & van Dieijen-Visser, M. P. (2012). A comprehensive review of upper reference limits reported for (high-)sensitivity cardiac troponin assays: The challenges that lie ahead. Clinical Chemistry and Laboratory Medicine, 50(5), 791-806. https://doi.org/10.1515/cclm-2011-0895
    • van Dieijen-Visser, M. P., Mingels, A. M., Jacobs, L. H., Cardinaels, E. P., Wodzig, K. W. H., Bekers, O., Klinkenberg, L. J., & Meex, S. J. R. (2012). Troponin, the best there is!Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 37, 15-18.
  • 2011
    • Meex, S. J. R., Andreo, U., Sparks, J. D., & Fisher, E. A. (2011). Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?Journal of Lipid Research, 52(1), 152-158. https://doi.org/10.1194/jlr.D008888
  • 2008
    • Meex, S. J., van Vliet-Ostaptchouk, J. V., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schalkwijk, C. G., Feskens, E. J. M., Blaak, E. E., Wijmenga, C., Hofker, M. H., Stehouwer, C. D., & de Bruin, T. W. (2008). Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians. Molecular Genetics and Metabolism, 94(3), 352-355. https://doi.org/10.1016/j.ymgme.2008.03.011
  • 2007
    • Meex, S. J., van Greevenbroek, M. M. J., Ayoubi, T. A., Vlietinck, R., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Vermeulen, V. M., Schalkwijk, C. G., Feskens, E. J., Boer, J. M., Stehouwer, C. D., van der Kallen, C. J. H., & de Bruin, T. W. (2007). Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. Journal of Clinical Endocrinology & Metabolism, 92(7), 2720-2725. https://doi.org/10.1210/jc.2006-2280
  • 2005
    • Meex, S. J. R., van der Kallen, C. J. H., van Greevenbroek, M. M., Eurlings, P. M., El Hasnaoui, M. M., Evelo, C. T., Lindsey, P. J., Luiken, J. J. F. P., Glatz, J. F., & de Bruin, T. W. (2005). Up-regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia. Faseb Journal, 19(14), 2063-2065. https://doi.org/10.1096/fj.04-2403fje