Yvonne Henskens

Associate professor

Dr Yvonne Henskens graduated with the specialisations in Biochemistry and Toxicology at Wageningen University. She worked on salivary cystatins in periodontal health and disease at the Department of Oral Biochemistry, Free University Amsterdam/Academic Centre for Dentistry (ACTA). After her PhD she started her specialisation for Clinical Chemistry at the Reinier de Graaf Gasthuis in Delft.

At this moment she is a clinical biochemist, working in laboratories for the past 15 years (Amsterdam Medical Centre and Maastricht UMC+). She has been responsible for the diagnostic tests concerning hematology, hemostasis and transfusion at Maastricht UMC+ since 2003.  She has special research interest in laboratory predictors of bleeding and in pre- and peri-operative management of coagulopathies: Active in the boards of the Dutch societies for hematologicallaboratories and clinical chemistry. Involved in training and education of medical and life sciences students, laboratory technicians and residents. Founder of a re-training programme on hemostasis and transfusion for technicians and clinical biochemists for the south-east part of the Netherlands.

Central Diagnostic Laboratory MUMC+
Department of Biochemistry
P. Debyelaan 25, 6229 HX Maastricht
Room number: 5.E2.001
T: +31(0)43 387 79 76

  • 2016
    • Eijgenraam, P., ten Cate, H., Henskens, Y., van den Ham, R., & ten Cate - Hoek , A. (2016). Effects of peri-operative bridging with low molecular weight heparins on coagulation during interruption of vitamin K antagonists: A mechanistic study. Thrombosis Research, 140, 59-65. https://doi.org/10.1016/j.thromres.2016.02.019
    • Baaten, C. C. F. M. J., Moenen, F. C. J. I., Henskens, Y. M. C., Swieringa, F., Wetzels, R., van Oerle, R., ten Cate, H., Beckers, E. A. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2016). Multiple functional defects in platelets from thrombocytopenic cancer patients undergoing chemotherapy. Thrombosis Research, 140S1, S171-S171. https://doi.org/10.1016/s0049-3848(16)30125-6
    • Swieringa, F., Baaten, C. C. F. M. J., Verdoold, R., Mastenbroek, T. G., Rijnveld, N., van der Laan, K. O., Breel, E. J., Collins, P. W., Lance, M. D., Henskens, Y. M. C., Cosemans, J. M. E. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2016). Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under Flow. Arteriosclerosis Thrombosis and Vascular Biology, 36(4), 692-699. https://doi.org/10.1161/ATVBAHA.115.306537
    • BRIDGE-BPD Consortium, Collaborators, Heemskerk, J., Henskens, Y., & Ouwehand, W. H. (2016). A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Science Translational Medicine, 8(328), [328ra30]. https://doi.org/10.1126/scitranslmed.aad7666
    • Kuiper, G-J., Kleinegris, M-C., van Oerle, R., Spronk, H., Lance, M., ten Cate, H., & Henskens, Y. (2016). Validation of a modified thromboelastometry approach to detect changes in fibrinolytic activity. Thrombosis Journal, 14, [1]. https://doi.org/10.1186/s12959-016-0076-2
    • Vries, M. J. A., van der Meijden, P. E. J., Henskens, Y. M. C., Ten Cate - Hoek, A., & ten Cate, H. (2016). Assessment of bleeding risk in patients with coronary artery disease on dual antiplatelet therapy A systematic review. Thrombosis and Haemostasis, 115(1), 7-24. https://doi.org/10.1160/TH15-04-0355
    • Straat, R., Habets, T., Vanderlocht, J., Tilanus, M., Beckers, E., Christiaans, M., & Henskens, Y. (2016). Anti-D vorming bij patiënten met rhesus-D incompatibele niertransplantaties. Tijdschrift voor Bloedtransfusie, 1, 17.
    • van Poucke, S., Stevens, K., Wetzels, R., Kicken, C., Verhezen, P., Theunissen, M., Kuiper, G-J., van Oerle, R., Henskens, Y., & Lance, M. (2016). Early platelet recovery following cardiac surgery with cardiopulmonary bypass. Platelets, 27(8), 751-757. https://doi.org/10.3109/09537104.2016.1173665
    • van Yperen, N., Geelen, I., Jöbses, C., Henskens, Y., Schouten, H., & Beckers, E. (2016). Invloed van ABO-mismatch op behandelingsuitkomsten en transfusiebehoefte na niet-myeloablatieve, allogene perifere bloedstamceltransplantaties. Tijdschrift voor Bloedtransfusie, 1, [28].
    • Slomp, J., Soons, J. W. P. H., Henskens, Y., de Rijke, Y. B., Vossen, R. C. R. M., & Kortlandt, W. (2016). Tarieven voor inboeken en uitgifte van transfusie-eenheden en hemovigilantiewerkzaamheden. Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 41, 54-55.
    • Moenen, F. C., Vries, M. C., Henskens, Y., ten Cate, H., Wetzels, R. J., Verhezen, P. W., van Oerle, R., & Beckers, E. (2016). Uitdagingen bij het screenen en diagnosticeren van milde bloedingsziekten. Nederlands Tijdschrift voor Hematologie, 13(5), 182-189. http://docplayer.nl/38565846-Uitdagingen-bij-het-screenen-en-diagnosticeren-van-milde-bloedingsziekten.html
    • Straat, R., Habets, T., Vanderlocht, J., Tilanus, M., Beckers, E., Christiaans, M., & Henskens, Y. (2016). Validatie ih-1000 voor geautomatiseerde antistof identificatie. Tijdschrift voor Bloedtransfusie, 1, 19-20.
  • 2015
    • Baaten, C. C. F. M. J., Veenstra, L. F., Wetzels, R., van Geffen, J. P., Swieringa, F., de Witt, S. M., Henskens, Y. M. C., Crijns, H., Nylander, S., van Giezen, J. J. J., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2015). Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication. Haematologica-the Hematology Journal, 100(9), 1131-1138. https://doi.org/10.3324/haematol.2014.122457
    • Hoek - ten Cate, A. J., ten Cate, H., Henskens, Y., van der Meijden, P. E. J., Spronk, H. M. H., & Wittens, C. (2015). Maastricht Consensus Conference on Thrombosis (MCCT): A roadmap for future research, February 11-13, 2015, Maastricht, The Netherlands. Thrombosis Research, 136, S1-S2. https://doi.org/10.1016/j.thromres.2015.07.033
    • Kicken, C., Van Poucke, S., Marcus, A. E., Lance, M. D., & Henskens, Y. (2015). Response of platelet concentrates to pressure and temperature changes without impairment of the in vitro function. Thrombosis Research, 135(4), 679-683. https://doi.org/10.1016/j.thromres.2015.01.004
    • Henskens, Y., van Noord, P., Beckers, E., & Lance, M. (2015). Vijf jaar ervaring met een op ROTEM gebaseerd algoritme voor de diagnose en behandeling van bloedverlies bij cardiothoracale chirurgie. Tijdschrift voor Bloedtransfusie, 8, 43-49.
  • 2014
    • Posthuma, J. J., Loeffen, R., van Oerle, R., Henskens, Y. M. C., ten Cate, H., Spronk, H. M. H., & van der Meijden, P. E. J. (2014). Long-term strenuous exercise induces a hypercoagulable state through contact activation. Thrombosis and Haemostasis, 111(6), 1197-1199. https://doi.org/10.1160/TH13-11-0963
    • Olde Engberink, R. H. G., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Nelemans, P. J., Lance, M. D., Beckers, E. A. M., & Henskens, Y. M. C. (2014). Rapid and Correct Prediction of Thrombocytopenia and Hypofibrinogenemia With Rotational Thromboelastometry in Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia, 28(2), 210-216. https://doi.org/10.1053/j.jvca.2013.12.004
    • Cornelis, T., Broers, N. J. H., Titulaer, D. C. L. M., Henskens, Y. M., van Oerle, R., van der Sande, F. M., Spronk, H. M., Vink, H., Leunissen, K. M., ten Cate, H., & Kooman, J. P. (2014). Effects of Ultrapure Hemodialysis and Low Molecular Weight Heparin on the Endothelial Surface Layer. Blood Purification, 38(3-4), 203-210. https://doi.org/10.1159/000369055
    • Frielink, L. M. J., Prinzen, L., Henskens, Y., Vossen, R., & Coumans, A. (2014). Kleihauer-Betketest, verre van ideaal. Nederlands tijdschrift voor obstetrie en gynaecologie, 127.
  • 2013
    • Grottke, O., Rossaint, R., Henskens, Y., van Oerle, R., ten Cate, H., & Spronk, H. H. (2013). Thrombin Generation Capacity of Prothrombin Complex Concentrate in an In Vitro Dilutional Model. PLOS ONE, 8(5), [e64100]. https://doi.org/10.1371/journal.pone.0064100
    • Prinzen, L., Staal, H. M., Rouwette, S. J. M., Beckers, E. A. M., ten Broeke, R. H. M., van Rhijn, L. W., & Henskens, Y. M. C. (2013). Triple Red Blood Cell Alloantibody Formation After Bone-Allograft Transplantation. American Journal of Transplantation, 13(1), 229-231. https://doi.org/10.1111/j.1600-6143.2012.04300.x
    • Tijink, M., Janssen, J., Timmer, M., Austen, J., Aldenhoff, Y., Kooman, J., Koole, L., Damoiseaux, J., van Oerle, R., Henskens, Y., & Stamatialis, D. (2013). Development of novel membranes for blood purification therapies based on copolymers of N-vinylpyrrolidone and n-butylmethacrylate. Journal of Materials Chemistry. B, Materials for Biology and Medicine, 1(44), 6066-6077. https://doi.org/10.1039/c3tb20964d
    • Lance, M. D., Henskens, Y., Nelemans, P., Theunissen, M. H. S., Van Oerle, R., Spronk, H. M., & Marcus, M. A. E. (2013). Do blood collection methods influence whole-blood platelet function analysis?Platelets, 24(4), 275-281. https://doi.org/10.3109/09537104.2012.689038
  • 2012
    • Lance, M. D., Kuiper, G. J. A. J. M., Sloep, M., Spronk, H. M. H., van Oerle, R., ten Cate, H., Marcus, M. A. E., & Henskens, Y. M. C. (2012). The effects of pneumatic tube system transport on ROTEM analysis and contact activation assessed by thrombin generation test. Thrombosis Research, 130(3), E147-E150. https://doi.org/10.1016/j.thromres.2012.05.002
    • de Lange, N. M., Lance, M. D., de Groot, R., Beckers, E. A. M., Henskens, Y. M., & Scheepers, H. C. J. (2012). Obstetric Hemorrhage and Coagulation: An Update. Thromboelastography, Thromboelastometry, and Conventional Coagulation Tests in the Diagnosis and Prediction of Postpartum Hemorrhage. Obstetrical & Gynecological Survey, 67(7), 426-435. https://doi.org/10.1097/OGX.0b013e3182605861
    • Lance, M. D., Marcus, M. A. E., van Oerle, R., Theunissen, H. M. S., & Henskens, Y. M. C. (2012). Platelet concentrate transport in pneumatic tube systems - does it work?Vox Sanguinis, 103(1), 79-82. https://doi.org/10.1111/j.1423-0410.2011.01580.x
    • Lance, M. D., Sloep, M., Henskens, Y. M. C., & Marcus, M. A. E. (2012). Mean Platelet Volume as a Diagnostic Marker for Cardiovascular Disease: Drawbacks of Preanalytical Conditions and Measuring Techniques. Clinical and Applied Thrombosis-Hemostasis, 18(6), 561-568. https://doi.org/10.1177/1076029612458147