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Social and economic background influences survival in intensive care: Research with societal impact

Social and economic background influences survival in intensive care: Research with societal impact

18 August 2026

A large-scale study by researchers from Maastricht UMC+ and Amsterdam UMC demonstrates that lower socioeconomic status (SES) of patients admitted to Dutch intensive care units contributes to worse survival.

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Fatma Karapinar appointed as Professor in Medication Safety

Fatma Karapinar appointed as Professor in Medication Safety

12 August 2026

As of 1 June 2026, Dr Fatma Karapinar has been appointed Professor of Medication Safety at Maastricht University.

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Carim Maastricht
Carim Maastricht

Arnoud van 't Hof

Professor

Prof. Arnoud van ‘t Hof is Interventional Cardiologist and head of the department of Interventional Cardiology in Maastricht University Medical Center and Zuyderland Medical Center in Heerlen, the Netherlands. He has a long-standing research history in cardiovascular medicine, particularly in the field of primary angioplasty and acute coronary syndromes, with special interest in pre-hospital diagnosis and triage in the ambulance. He has been (co-) chairing international multi-center clinical trials in this field. He is a board member of the Acute Cardiac Care Association (ACCA) and editorial board member of the European Heart Journal Acute Cardiovascular Care and the Netherlands Heart Journal. He chaired the board of directors of the National Cardiovascular Data Registry (NCDR, now Nederlandse Hart Registratie (NHR) with specific interest for value based healthcare (VBHC) and data science. He recently joined the European Association of Preventive Cardiology (EAPC) with research on Cardiac Rehabilitation, Cardiovascular Prevention and Sports Medicine.

Prof. Arnoud van ‘t Hof has authored over 350 publications in peer-reviewed cardiovascular journals. He is an elected fellow of the ESC.

Arnoud-van-t-hof_5dca72d690a3c

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht

  • 2018
    • Valgimigli, M., Frigoli, E., Leonardi, S., Vranckx, P., Rothenbuhler, M., Tebaldi, M., Varbella, F., Calabro, P., Garducci, S., Rubartelli, P., Briguori, C., Ando, G., Ferrario, M., Limbruno, U., Garbo, R., Sganzerla, P., Russo, F., Nazzaro, M., Lupi, A., ... MATRIX Investigators (2018). Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial. Lancet, 392(10150), 835-848. https://doi.org/10.1016/S0140-6736(18)31714-8
    • Arslan, F., Bongartz, L., ten Berg, J. M., Jukema, J. W., Appelman, Y., Liem, A. H., de Winter, R. J., van't Hof, A. W. J., & Damman, P. (2018). 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: comments from the Dutch ACS working group. Netherlands Heart Journal, 26(9), 417-421. https://doi.org/10.1007/s12471-018-1134-0
    • Roolvink, V., Ottervanger, J. P., Ibanez, B., Dambrink, J. H., Gosselink, M., Kedhi, E., van Royen, N., Lipsic, E., Remkes, W., Piek, J., Fuster, V., & van't Hof, A. (2018). One-year clinical outcome of early administration of intravenous beta-blockers in patients with ST-segment elevation myocardial infarction before primary percutaneous coronary reperfusion. Eurointervention, 14(6), 688-691. https://doi.org/10.4244/EIJ-D-17-00776
    • Hermanides, R. S., Kilic, S., & van't Hof, A. W. J. (2018). Optimal pharmacological therapy in ST-elevation myocardial infarction-a review. Netherlands Heart Journal, 26(6), 296-310. https://doi.org/10.1007/s12471-018-1112-6
    • Badings, E. A., Hermanides, R. S., The, S. H. K., Dambrink, J.-H. E., Rasoul, S., Van Wijngaarden, J., Van't Riet, E., Kolkman, E., Remkes, W. S., Tjeerdsma, G., Van Der Wielen, M. L. J., Lok, D. J. A., Suryapranata, H., & Van't Hof, A. W. J. (2018). Comparison of Outcomes and Intervention Among Patients With Non-ST-Segment Elevation Acute Myocardial Infarction of Those With a Left Circumflex Versus Those With a Non-Left Circumflex-Related Coronary Artery (From the ELISA-3 Trial). American Journal of Cardiology, 121(10), 1123-1128. https://doi.org/10.1016/j.amjcard.2018.01.031
    • Hoedemaker, N. P. G., Damman, P., Ottervanger, J. P., Dambrink, J. H. E., Gosselink, A. T. M., Kedhi, E., Kolkman, E., de Winter, R. J., & van 't Hof, A. J. (2018). Trends in optimal medical therapy prescription and mortality after admission for acute coronary syndrome: a 9-year experience in a real-world setting . European Heart Journal-Cardiovascular Pharmacotherapy, 4(2), 102-110. https://doi.org/10.1093/ehjcvp/pvy005
    • Gargiulo, G., Carrara, G., Frigoli, E., Vranckx, P., Leonardi, S., Ciociano, N., Campo, G., Varbella, F., Calabro, P., Garducci, S., Iannone, A., Briguori, C., Ando, G., Crimi, G., Limbruno, U., Garbo, R., Sganzerla, P., Russo, F., Lupi, A., ... Valgimigli, M. (2018). Bivalirudin or Heparin in Patients Undergoing Invasive Management of Acute Coronary Syndromes. Journal of the American College of Cardiology, 71(11), 1231-1242. https://doi.org/10.1016/j.jacc.2018.01.033
    • Kilic, S., Fabris, E., van't Hof, A. W. J., Hamm, C. W., Lapostolle, F., Lassen, J. F., Tsatsaris, A., Diallo, A., Vicaut, E., Montalescot, G., & ATLANTIC Investigators (2018). Thrombus aspiration and prehospital ticagrelor administration in ST-elevation myocardial infarction: Findings from the ATLANTIC trial. American Heart Journal, 196, 1-8. https://doi.org/10.1016/j.ahj.2017.09.018
    • Bagai, A., Goodman, S. G., Cantor, W. J., Vicaut, E., Bolognese, L., Cequier, A., Chettibi, M., Hammett, C. J., Huber, K., Janzon, M., Lapostolle, F., Lassen, J. F., Merkely, B., Storey, R. F., Ten Berg, J. M., Zeymer, U., Diallo, A., Hamm, C. W., Tsatsaris, A., ... Montalescot, G. (2018). Duration of ischemia and treatment effects of pre- versus in-hospital ticagrelor in patients with ST-segment elevation myocardial infarction: Insights from the ATLANTIC study. American Heart Journal, 196, 56-64. https://doi.org/10.1016/j.ahj.2017.10.021
    • Marchal, S., van't Hof, A. W. J., & Hollander, M. (2018). The new European guideline on cardiovascular disease prevention; how to make progress in general practice? Commentary on: Main messages for primary care from the 2016 European Guidelines on cardiovascular disease prevention in clinical practice. European Journal of General Practice, 24(1), 57-59. https://doi.org/10.1080/13814788.2017.1401063
  • 2017
    • Fabris, E., Kilic, S., Schellings, D. A. A. M., ten Berg, J. M., Kennedy, M. W., van Houwelingen, K. G., Giannitsis, E., Kolkman, E., Ottervanger, J. P., Hamm, C., & van't Hof, A. W. J. (2017). Long-term mortality and prehospital tirofiban treatment in patients with ST elevation myocardial infarction. Heart, 103(19), 1515-1520. https://doi.org/10.1136/heartjnl-2017-311181
    • Damman, P., & Van't Hof, A. W. (2017). Moeten we de HEART-score volgen bij pijn op de borst?Nederlands Tijdschrift voor Geneeskunde, 161(43), Article D1945.
    • Badings, E. A., Remkes, W. S., The, S. H. K., Dambrink, J. H. E., Tjeerdsma, G., Rasoul, S., Timmer, J. R., van der Wielen, M. L. J., Lok, D. J. A., Hermanides, R. S., Van Wijngaarden, J., Suryapranata, H., & van't Hof, A. W. J. (2017). Two-year outcome after early or late Intervention in non-ST elevation acute coronary syndrome. Open Heart, 4(1). https://doi.org/10.1136/openhrt-2016-000538
    • Klomp, W. W. J., Bruinsma, G. J. B. B., Van't Hof, A. W. J., Grandjean, J. G., & Nierich, A. P. (2017). A Protocol for Diagnosis and Management of Aortic Atherosclerosis in Cardiac Surgery Patients. International Journal of Vascular Medicine, Article 1874395. https://doi.org/10.1155/2017/1874395
    • Klomp, W. W. J., Moons, C. G. M., Nierich, A. P., Bruinsma, G. J. B. B., van't Hof, A. W. J., Grandjean, J. G., & Peelen, L. M. (2017). Impact of Modified Transesophageal Echocardiography on Mortality and Stroke after Cardiac Surgery: A Large Cohort Study. International Journal of Vascular Medicine, Article 1857069. https://doi.org/10.1155/2017/1857069
  • 2016
    • Badings, E. A., Remkes, W. S., The, S. H. K., Dambrink, J.-H. E., Tjeerdsma, G., Rasoul, S., Timmer, J. R., van der Wielen, M. L. J., Lok, D. J. A., Hermanides, R., van Wijngaarden, J., Suryapranata, H., & van't Hof, A. W. J. (2016). Early or late intervention in patients with transient ST-segment elevation acute coronary syndrome: Subgroup analysis of the ELISA-3 trial. Catheterization and Cardiovascular interventions, 88(5), 755-764. https://doi.org/10.1002/ccd.26719
    • Remkes, W. S., Badings, E. A., Hermanides, R. S., Rasoul, S., Dambrink, J.-H. E., Koopmans, P. C., The, S. H. K., Ottervanger, J. P., Gosselink, A. T. M., Hoorntje, J., Suryapranata, H., & van 't Hof, A. W. J. (2016). Randomised comparison of drugeluting versus bare-metal stenting in patients with non-ST elevation myocardial infarction. Open Heart, 3(2), Article e000455. https://doi.org/10.1136/openhrt-2016-000455
    • Roolvink, V., Ibanez, B., Ottervanger, J. P., Pizarro, G., van Royen, N., Mateos, A., Dambrink, J.-H. E., Escalera, N., Lipsic, E., Albarran, A., Fernandez-Ortiz, A., Fernandez-Aviles, F., Goicolea, J., Botas, J., Remkes, W., Hernandez-Jaras, V., Kedhi, E., Zamorano, J. L., Navarro, F., ... Van 't Hof, A. W. J. (2016). Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention. Journal of the American College of Cardiology, 67(23), 2705-2715. https://doi.org/10.1016/j.jacc.2016.03.522
    • Nijenhuis, V. J., Bennaghmouch, N., Hassell, M., Baan, J., van Kuijk, J. P., Agostoni, P., van't Hof, A., Kievit, P. C., Veenstra, L., van der Harst, P., van den Heuvel, A. F. M., den Heijer, P., Kelder, J. C., Deneer, V. H., van der Kley, F., Onorati, F., Collet, J. P., Maisano, F., Latib, A., ... ten Berg, J. M. (2016). Rationale and design of POPular-TAVI: antiPlatelet therapy fOr Patients undergoing Transcatheter Aortic Valve Implantation. American Heart Journal, 173, 77-85. https://doi.org/10.1016/j.ahj.2015.11.008
    • Badings, E. A., Remkes, W. S., Dambrink, J.-H. E., The, S. H. K., Van Wijngaarden, J., Tjeerdsma, G., Rasoul, S., Timmer, J. R., van der Wielen, M. L. J., Lok, D. J. A., & van 't Hof, A. W. J. (2016). Timing of intervention in high-risk non-ST-elevation acute coronary syndromes in PCI versus non-PCI centres: Sub-group analysis of the ELISA-3 trial. Netherlands Heart Journal, 24(3), 181-187. https://doi.org/10.1007/s12471-015-0801-7
  • 2014
    • Schellings, D. A. A. M., Adiyaman, A., Giannitsis, E., Hamm, C., Suryapranata, H., Ten Berg, J. M., Hoorntje, J. C. A., & Van't Hof, A. W. J. (2014). Early discharge after primary percutaneous coronary intervention: the added value of N-terminal pro-brain natriuretic peptide to the Zwolle Risk Score. Journal of the American Heart Association, 3(6), Article e001089. https://doi.org/10.1161/JAHA.114.001089
    • Otten, A. M., Ottervanger, J. P., Kloosterman, A., van't Hof, A. W. J., Marcel Gosselink, A. T., Dambrink, J.-H. E., Hoorntje, J. C. A., Suryapranata, H., & Maas, A. H. E. M. (2014). Treatment assignment in young women with spontaneous coronary artery dissection. International Journal of Cardiology, 176(3), 1223-4. https://doi.org/10.1016/j.ijcard.2014.07.218
    • Remkes, W. S., Somi, S., Roolvink, V., Rasoul, S., Ottervanger, J. P., Gosselink, A. T. M., Hoorntje, J. C. A., Dambrink, J.-H. E., de Boer, M.-J., Suryapranata, H., van 't Hof, A. W. J., & Acute Myocardial Infarction Study Group (2014). Direct drug-eluting stenting to reduce stent restenosis: a randomized comparison of direct stent implantation to conventional stenting with pre-dilation or provisional stenting in elective PCI patients. Jacc-Cardiovascular Interventions, 7(7), 751-8. https://doi.org/10.1016/j.jcin.2014.02.012
    • Kilic, S., Ottervanger, J. P., Dambrink, J.-H. E., Hoorntje, J. C. A., Koopmans, P. C., Gosselink, A. T. M., Suryapranata, H., van 't Hof, A. W. J., & Zwolle Myocardial Infarction Study Group (2014). The effect of thrombus aspiration during primary percutaneous coronary intervention on clinical outcome in daily clinical practice. Thrombosis and Haemostasis, 111(1), 165-71. https://doi.org/10.1160/TH13-05-0433
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