Kevin Vernooy

Assistant Professor

Dr Kevin Vernooy became a medical docter in 2003 at the Maastricht University. He finished his PhD in 2006 on cardiac resynchronisation therapy at Maastricht University. In 2012, he finished his Cardiology training and subspecialiation in the treatment of cardiac arrhythmias as an clinical electrophysiologist at Maastricht UMC+

Since 2012, he has been working at Maastricht UMC+ as a clinical electrophysiologist. Since 2014, he ihas been heading the divion of clinical electrophysiology in the Department of Cardiology and since 2018 the research on cardiac arrhythmias at the Department of Cardiology at the Radboud University Medical Center in Nijmegen.

His research focusses on the invasive treatment of cardiac arrhythmias in patients with heart failure.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
M: +31(0)620 198 657

  • 2020
    • Verdonschot, J. A. J., Merken, J. J., van Stipdonk, A. M. W., Pliger, P., Derks, K. W. J., Wang, P., Henkens, M. T. H. M., van Paassen, P., Hamid, M. A. A., van Empel, V. P. M., Knackstedt, C., Luermans, J. G. L. M., Crijns, H. J. G. M., Brunner-La Rocca, H-P., Brunner, H. G., Poelzl, G., Vernooy, K., Heymans, S. R. B., & Hazebroek, M. R. (2020). Cardiac Inflammation Impedes Response to Cardiac Resynchronization Therapy in Patients With Idiopathic Dilated Cardiomyopathy. Circulation-Arrhythmia and Electrophysiology, 13(11), 1311-1320. https://doi.org/10.1161/CIRCEP.120.008727
    • Salden, F., Luermans, J. G., Van Stipdonk, A. M. W., Allaart, C. P., Meine, M., Prinzen, F. W., & Vernooy, K. (2020). Improving atrioventricular coupling in heart failure patients with PR prolongation, the ReachPR Trial. European Heart Journal, 41, 1036-1036.
    • Rickard, J., Jackson, K., Biffi, M., Vernooy, K., Bank, A., Cerkvenik, J., Ghosh, S., & Gold, M. R. (2020). The ECG Belt for CRT response trial: Design and clinical protocol. Pacing and Clinical Electrophysiology, 43(10), 1063-1071. https://doi.org/10.1111/pace.13985
    • van Veldhuisen, D. J., van Woerden, G., Gorter, T. M., van Empel, V. P. M., Manintveld, O. C., Tieleman, R. G., Maass, A. H., Vernooy, K., Westenbrink, B. D., van Gelder, I. C., & Rienstra, M. (2020). Ventricular tachyarrhythmia detection by implantable loop recording in patients with heart failure and preserved ejection fraction: the VIP-HF study. European journal of heart failure, 22(10), 1923-1929. https://doi.org/10.1002/ejhf.1970
    • Knops, R. E., Nordkamp, L. R. A. O., Delnoy, P-P. H. M., Boersma, L. V. A., Kuschyk, J., El-Chami, M. F., Bonnemeier, H., Behr, E. R., Brouwer, T. F., Kaab, S., Mittal, S., Quast, A-F. B. E., Smeding, L., van der Stuijt, W., de Weger, A., de Wilde, K. C., Bijsterveld, N. R., Richter, S., Brouwer, M. A., ... PRAETORIAN Investigators (2020). Subcutaneous or Transvenous Defibrillator Therapy. New England Journal of Medicine, 383(6), 526-536. https://doi.org/10.1056/NEJMoa1915932
    • Frontera, A., Strik, M., Eschalier, R., Biffi, M., Pereira, B., Welte, N., Chauvel, R., Mondoly, P., Laborderie, J., Bernis, J-P., Clementy, N., Reuter, S., Garrigue, S., Deplagne, A., Vernooy, K., Pillois, X., Haissaguerre, M., Dubois, R., Ritter, P., ... Ploux, S. (2020). Electrogram morphology discriminators in implantable cardioverter defibrillators: A comparative evaluation. Journal of Cardiovascular Electrophysiology, 31(6), 1493-1506. https://doi.org/10.1111/jce.14518
    • Pluymaekers, N. A. H. A., Hermans, A. N. L., van der Velden, R. M. J., den Uijl, D. W., Vorstermans, B., Buskes, S., Hendriks, J. M., Vernooy, K., Crijns, H. J. G. M., & Linz, D. (2020). On-demand app-based rate and rhythm monitoring to manage atrial fibrillation through teleconsultations during COVID-19. IJC Heart & Vasculature, 28, [100533]. https://doi.org/10.1016/j.ijcha.2020.100533
    • Kloosterman, M., van Stipdonk, A. M. W., ter Horst, I., Rienstra, M., Van Gelder, I. C., Vos, M. A., Prinzen, F. W., Meine, M., Vernooy, K., & Maass, A. H. (2020). Association between heart failure aetiology and magnitude of echocardiographic remodelling and outcome of cardiac resynchronization therapy. Esc heart failure, 7(2), 645-653. https://doi.org/10.1002/ehf2.12624
    • Salden, F. C. W. M., Luermans, J. G. L. M., Westra, S. W., Weijs, B., Engels, E. B., Heckman, L. I. B., Lamerichs, L. J. M., Janssen, M. H. G., Clerx, K. J. H., Cornelussen, R., Ghosh, S., Prinzen, F. W., & Vernooy, K. (2020). Short-Term Hemodynamic and Electrophysiological Effects of Cardiac Resynchronization by Left Ventricular Septal Pacing. Journal of the American College of Cardiology, 75(4), 347-359. https://doi.org/10.1016/j.jacc.2019.11.040
    • van Stipdonk, A. M. W., Hoogland, R., Ter Horst, I., Kloosterman, M., Vanbelle, S., Crijns, H. J. G. M., Prinzen, F. W., Meine, M., Maass, A. H., & Vernooy, K. (2020). Evaluating Electrocardiography-Based Identification of Cardiac Resynchronization Therapy Responders Beyond Current Left Bundle Branch Block Definitions. JACC: Clinical Electrophysiology, 6(2), 193-203. https://doi.org/10.1016/j.jacep.2019.10.009
    • Salden, O. A. E., Vernooy, K., van Stipdonk, A. M. W., Cramer, M. J., Prinzen, F. W., & Meine, M. (2020). Strategies to Improve Selection of Patients Without Typical Left Bundle Branch Block for Cardiac Resynchronization Therapy. JACC: Clinical Electrophysiology, 6(2), 129-142. https://doi.org/10.1016/j.jacep.2019.11.018
    • Pluymaekers, N. A. H. A., Hermans, A. N. L., Linz, D. K., Dudink, E. A. M. P., Luermans, J. G. L. M., Weijs, B., Vernooy, K., & Crijns, H. J. G. M. (2020). Frequency and Determinants of Spontaneous Conversion to Sinus Rhythm in Patients Presenting to the Emergency Department with Recent-onset Atrial Fibrillation: A Systematic Review. Arrhythmia & Electrophysiology Review, 9(4), 195-201. https://doi.org/10.15420/aer.2020.34
    • Plesinger, F., van Stipdonk, A. M. W., Smisek, R., Halamek, J., Jurak, P., Maass, A. H., Meine, M., Vernooy, K., & Prinzen, F. W. (2020). Fully automated QRS area measurement for predicting response to cardiac resynchronization therapy. Journal of Electrocardiology, 63, 159-163. https://doi.org/10.1016/j.jelectrocard.2019.07.003
  • 2019
    • Evertz, R., Houck, C. A., ten Cate, T., Duijnhouwer, A. L., Beukema, R., Westra, S., Vernooy, K., & de Groot, N. M. S. (2019). Concomitant pulmonary vein isolation and percutaneous closure of atrial septal defects: A pilot project. Congenital Heart Disease, 14(6), 1123-1129. https://doi.org/10.1111/chd.12859
    • Lee, A. W. C., Nguyen, U. C., Razeghi, O., Gould, J., Sidhu, B. S., Sieniewicz, B., Behar, J., Mafi-Rad, M., Plank, G., Prinzen, F. W., Rinaldi, C. A., Vernooy, K., & Niederer, S. (2019). A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data. Medical Image Analysis, 57, 197-213. https://doi.org/10.1016/j.media.2019.06.017
    • Zweerink, A., Salden, O. A. E., van Everdingen, W. M., de Roest, G. J., van de Ven, P. M., Cramer, M. J., Doevendans, P. A., van Rossum, A. C., Vernooy, K., Prinzen, F. W., Meine, M., & Allaart, C. P. (2019). Hemodynamic Optimization in Cardiac Resynchronization Therapy: Should We Aim for dP/dtmax or Stroke Work?JACC: Clinical Electrophysiology, 5(9), 1013-1025. https://doi.org/10.1016/j.jacep.2019.05.020
    • Lankveld, T. A. R., Vernooy, K., Crijns, H. J. G. M., & Linz, D. (2019). How to make catheter ablation available world-wide?IJC Heart and Vasculature, 24, [100411]. https://doi.org/10.1016/j.ijcha.2019.100411
    • den Uijl, D. W., Crijns, H. J. G. M., Vernooy, K., & Linz, D. (2019). Hypnotic communication during atrial fibrillation ablation: Another clinical application of hypnotherapy?IJC Heart and Vasculature, 24, [100408]. https://doi.org/10.1016/j.ijcha.2019.100408
    • Linz, D., Baumert, M., Desteghe, L., Kadhim, K., Vernooy, K., Kalman, J. M., Dobrev, D., Arzt, M., Sastry, M., Crijns, H. J. G. M., Schotten, U., Cowie, M. R., McEvoy, R. D., Heidbuchel, H., Hendriks, J., Sanders, P., & Lau, D. H. (2019). Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring. IJC Heart and Vasculature, 24, 1-7. [100424]. https://doi.org/10.1016/j.ijcha.2019.100424
    • van Stipdonk, A. M. W., Vanbelle, S., ter Horst, I. A. H., Luermans, J. G., Meine, M., Maass, A. H., Auricchio, A., Prinzen, F. W., & Vernooy, K. (2019). Large variability in clinical judgement and definitions of left bundle branch block to identify candidates for cardiac resynchronisation therapy. International Journal of Cardiology, 286, 61-65. https://doi.org/10.1016/j.ijcard.2019.01.051
    • Vroomen, M., La Meir, M., Maesen, B., Luermans, J. G. L., Vernooy, K., Essers, B., de Greef, B. T. A., Maessen, J. G., Crijns, H. J., & Pison, L. (2019). Hybrid thoracoscopic surgical and transvenous catheter ablation versus transvenous catheter ablation in persistent and longstanding persistent atrial fibrillation (HARTCAP-AF): study protocol for a randomized trial. Trials, 20, [370]. https://doi.org/10.1186/s13063-019-3365-9
    • Bogdan, S., Refaat, M., Chudzik, M., Balsam, P., Kosiuk, J., Conte, G., Vernooy, K., & Kutyifa, V. (2019). Career building in countries with electrophysiology underdevelopment: roadblocks and solutionsan EHRA Young EP Report. EP Europace, 21(6), 978-980. https://doi.org/10.1093/europace/euz017
    • Vroomen, M., Maesen, B., La Meir, M., Luermans, J. G. L., Vernooy, K., Maessen, J. G., Crijns, H. J., & Pison, L. (2019). Hybrid Ablation of Ventricular Tachycardia: a Single-Centre Experience. Journal of Atrial Fibrillation, 11(5), [2118]. https://doi.org/10.4022/jafib.2118
    • Molenaar, M. M. D., Timmermans, C. C., Hesselink, T., Scholten, M. F., ter Bekke, R. M. A., Luermans, J. G. L. M., Brusse-Keizer, M., Kraaier, K., ten Haken, B., Grandjean, J. G., Vernooy, K., & van Opstal, J. M. (2019). Shorter cryoballoon applications times do effect efficacy but result in less phrenic nerve injury: Results of the randomized 123 study. Pacing and Clinical Electrophysiology, 42(5), 508-514. https://doi.org/10.1111/pace.13626
    • Nguyen, U. C., Cluitmans, M. J. M., Strik, M., Luermans, J. G., Gommers, S., Wildberger, J. E., Bekkers, S. C. A. M., Volders, P. G. A., Mihl, C., Prinzen, F. W., & Vernooy, K. (2019). Integration of cardiac magnetic resonance imaging, electrocardiographic imaging, and coronary venous computed tomography angiography for guidance of left ventricular lead positioning. EP Europace, 21(4), 626-635. https://doi.org/10.1093/europace/euy292
    • van Stipdonk, A. M. W., ter Horst, I., Kloosterman, M., Engels, E. B., Rienstra, M., Crijns, H. J. G. M., Vos, M. A., van Gelder, I. C., Prinzen, F. W., Meine, M., Maass, A., & Vernooy, K. (2019). Response to Letter From Vereckei Regarding, "QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy". Circulation-Arrhythmia and Electrophysiology, 12(4), [007297]. https://doi.org/10.1161/CIRCEP.119.007297
    • Vernooy, K., Kutyifa, V., Conte, G., Bogdan, S., Balsam, P., Nielsen, J. C., & Kosiuk, J. (2019). Survey on the research activities within the EHRA Young EP community. EP Europace, 21(4), 670-672. https://doi.org/10.1093/europace/euy294
    • Strik, M., den Uijl, D., Vernooy, K., & Luermans, J. (2019). Unsuccessful antitachycardia pacing: What is the mechanism?Pacing and Clinical Electrophysiology, 42(4), 464-466. https://doi.org/10.1111/pace.13625
    • Conte, G., Kosiuk, J., Bogdan, S., Balsam, P., Vernooy, K., Nielsen, J. C., & Kutyifa, V. (2019). Current status of interventional cardiac electrophysiology training in ESC member countries: an EHRAYoung EP Report. EP Europace, 21(3), 522-524. https://doi.org/10.1093/europace/euy277
    • Odening, K. E., Deiss, S., Dilling-Boer, D., Didenko, M., Eriksson, U., Nedios, S., Ng, F. S., Roca Luque, I., Sanchez Borque, P., Vernooy, K., Wijnmaalen, A. P., Yorgun, H., & DAS CAM Participants 2017 2018 (2019). Mechanisms of sex differences in atrial fibrillation: role of hormones and differences in electrophysiology, structure, function, and remodelling. EP Europace, 21(3), 366-376. https://doi.org/10.1093/europace/euy215
    • Willemen, E., Schreurs, R., Huntjens, P. R., Strik, M., Plank, G., Vigmond, E., Walmsley, J., Vernooy, K., Delhaas, T., Prinzen, F. W., & Lumens, J. (2019). The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach. Frontiers in physiology, 10, 1-13. [17]. https://doi.org/10.3389/fphys.2019.00017
    • van Everdingen, W. M., Zweerink, A., Salden, O. A. E., Cramer, M. J., Doevendans, P. A., van Rossum, A. C., Prinzen, F. W., Vernooy, K., Allaart, C. P., & Meine, M. (2019). Atrioventricular optimization in cardiac resynchronization therapy with quadripolar leads: should we optimize every pacing configuration including multi-point pacing?EP Europace, 21(1), E11-E19. https://doi.org/10.1093/europace/euy138
  • 2018
    • Chau Nguyen, U., Verzaal, N. J., van Nieuwenhoven, F. A., Vernooy, K., & Prinzen, F. (2018). Pathobiology of cardiac dyssynchrony and resynchronization therapy. EP Europace, 20(12), 1898-1909. https://doi.org/10.1093/europace/euy035
    • Zweerink, A., van Everdingen, W. M., Nijveldt, R., Salden, O. A. E., Meine, M., Maass, A. H., Vernooy, K., de Langer, F. J., Vos, M. A., Croisille, P., Clarysse, P., Geelhoed, B., Rienstra, M., van Gelder, I. C., van Rossum, A. C., Cramer, M. J., & Allaart, C. P. (2018). Strain imaging to predict response to cardiac resynchronization therapy: a systematic comparison of strain parameters using multiple imaging techniques. Esc heart failure, 5(6), 1130-1140. https://doi.org/10.1002/ehf2.12335
    • van Stipdonk, A. M. W., ter Horst, I., Kloosterman, M., Engels, E. B., Rienstra, M., Crijns, H. J. G. M., Vos, M. A., van Gelder, I. C., Prinzen, F. W., Meine, M., Maass, A. H., & Vernooy, K. (2018). QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy. Circulation-Arrhythmia and Electrophysiology, 11(12), [006497]. https://doi.org/10.1161/CIRCEP.118.006497
    • Nguyen, U. C., Cluitmans, M. J. M., Prinzen, F. W., Mihl, C., & Vernooy, K. (2018). Reply to the letter from Bhagirath etal. Imaging for cardiac resynchronisation therapy requires cardiac magnetic resonance. Netherlands Heart Journal, 26(12), 641-642. https://doi.org/10.1007/s12471-018-1196-z
    • Strik, M., Ploux, S., Huntjens, P. R., Nguyen, U. C., Frontera, A., Eschalier, R., Dubois, R., Ritter, P., Klotz, N., Vernooy, K., Haissaguerre, M., Crijns, H. J. G. M., Prinzen, F. W., & Bordachar, P. (2018). Response to cardiac resynchronization therapy is determined by intrinsic electrical substrate rather than by its modification. International Journal of Cardiology, 270, 143-148. https://doi.org/10.1016/j.ijcard.2018.06.005
    • Uyen Chau Nguyen, N. V., Potse, M., Vernooy, K., Mafi-Rad, M., Heijman, J., Caputo, M. L., Conte, G., Regoli, F., Krause, R., Moccetti, T., Auricchio, A., Prinzen, F. W., & Maffessanti, F. (2018). A left bundle branch block activation sequence and ventricular pacing influence voltage amplitudes: an in vivo and in silico study. EP Europace, 20, 77-86. https://doi.org/10.1093/europace/euy233
    • Caputo, M. L., van Stipdonk, A., Illner, A., D'Ambrosio, G., Regoli, F., Conte, G., Moccetti, T., Klersy, C., Prinzen, F. W., Vernooy, K., & Auricchio, A. (2018). The definition of left bundle branch block influences the response to cardiac resynchronization therapy. International Journal of Cardiology, 269, 165-169. https://doi.org/10.1016/j.ijcard.2018.07.060
    • Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Boersma, L., Erkuner, O., Gelissen, M., van Dijk, V., Wijffels, M., Dinh, D., Vernooy, K., Crijns, H. J. G. M., Balt, J., & Luermans, J. G. L. M. (2018). External electrical cardioversion in patients with cardiac implantable electronic devices: Is it safe and is immediate device interrogation necessary?Pacing and Clinical Electrophysiology, 41(10), 1336-1340. https://doi.org/10.1111/pace.13467
    • Nguyen, U. C., Cluitmans, M. J. M., Luermans, J. G. L. M., Strik, M., de Vos, C. B., Kietselaer, B. L. J. H., Wildberger, J. E., Prinzen, F. W., Mihl, C., & Vernooy, K. (2018). Visualisation of coronary venous anatomy by computed tomography angiography prior to cardiac resynchronisation therapy implantation. Netherlands Heart Journal, 26(9), 433-440. https://doi.org/10.1007/s12471-018-1132-2
    • Strik, M., Vernooy, K., & Prinzen, F. W. (2018). Too old to shock? Questioning added benefit of ICD in elderly CRT patients. International Journal of Cardiology, 263, 65-66. https://doi.org/10.1016/j.ijcard.2018.04.036
    • Salden, F. C. W. M., Kutyifa, V., Stockburger, M., Prinzen, F. W., & Vernooy, K. (2018). Atrioventricular dromotropathy: evidence for a distinctive entity in heart failure with prolonged PR interval?EP Europace, 20(7), 1067-1077. https://doi.org/10.1093/europace/eux207
    • Engels, E. B., Mafi-Rad, M., Hermans, B. J. M., Aranda, A., van Stipdonk, A. M. W., Rienstra, M., Scheerder, C. O. S., Maass, A. H., Prinzen, F. W., & Vernooy, K. (2018). Tailoring device settings in cardiac resynchronization therapy using electrograms from pacing electrodes. EP Europace, 20(7), 1146-1153. https://doi.org/10.1093/europace/eux208
    • Nguyen, C., Claridge, S., Vernooy, K., Engels, E. B., Razavi, R., Rinaldi, C. A., Chen, Z., & Prinzen, F. W. (2018). Relationship between vectorcardiographic QRS(area), myocardial scar quantification, and response to cardiac resynchronization therapy. Journal of Electrocardiology, 51(3), 457-463. https://doi.org/10.1016/j.jelectrocard.2018.01.009
    • Maesen, B., Pison, L., Vroomen, M., Luermans, J. G., Vernooy, K., Maessen, J. G., Crijns, H. J., & LaMeir, M. (2018). Three-year follow-up of hybrid ablation for atrial fibrillation. European Journal of Cardio-Thoracic Surgery, 53, 26-32. https://doi.org/10.1093/ejcts/ezy117
    • van Everdingen, W. M., Zweerink, A., Cramer, M. J., Doevendans, P. A., Nguyen, C., van Rossum, A. C., Prinzen, F. W., Vernooy, K., Allaart, C. P., & Meine, M. (2018). Can We Use the Intrinsic Left Ventricular Delay (QLV) to Optimize the Pacing Configuration for Cardiac Resynchronization Therapy With a Quadripolar Left Ventricular Lead?Circulation-Arrhythmia and Electrophysiology, 11(3), [005912]. https://doi.org/10.1161/CIRCEP.117.005912
    • van Everdingen, W. M., Zweerink, A., Nijveldt, R., Salden, O. A. E., Meine, M., Maass, A. H., Vernooy, K., De Lange, F. J., van Rossum, A. C., Croisille, P., Clarysse, P., Geelhoed, B., Rienstra, M., Van Gelder, I. C., Vos, M. A., Allaart, C. P., & Cramer, M. J. (2018). Comparison of strain imaging techniques in CRT candidates: CMR tagging, CMR feature tracking and speckle tracking echocardiography. International Journal of Cardiovascular Imaging, 34(3), 443-456. https://doi.org/10.1007/s10554-017-1253-5
    • Maass, A. H., Vernooy, K., Cramer, M. J., Vos, M. A., Rienstra, M., Van Gelder, I. C., & MARC Investigators (2018). Refining success of cardiac resynchronization therapy using a simple score predicting the amount of reverse ventricular remodelling: results from the MARC study - authors reply. EP Europace, 20(2), 393-393. https://doi.org/10.1093/europace/eux169
    • Maass, A. H., Vernooy, K., Wijers, S. C., van 't Sant, J., Cramer, M. J., Meine, M., Allaart, C. P., De Lange, F. J., Prinzen, F. W., Gerritse, B., Erdtsieck, E., Scheerder, C. O. S., Hill, M. R. S., Scholten, M., Kloosterman, M., ter Horst, I. A. H., Voors, A. A., Vos, M. A., Rienstra, M., & Van Gelder, I. C. (2018). Refining success of cardiac resynchronization therapy using a simple score predicting the amount of reverse ventricular remodelling: results from the Markers and Response to CRT (MARC) study. EP Europace, 20(2), E1-E10. https://doi.org/10.1093/europace/euw445