Uli Schotten

Professor

Professor Uli Schotten studied medicine at the universities of Aachen, Glasgow, and Valetta. After four years of training in cardiology at the University Hospital of Aachen, he joined the Department of Physiology at Maastricht University in 1998, first as a scholar of the Academy of Sciences of North-Rhine Westfalia and from 1999 on as a staff member of the department. He defended his thesis 'Mechanisms of Atrial Paralysis in Atrial Fibrillation' at Maastricht University in 2003, and received his habilitation in Experimental Cardiology at the University Hospital in Aachen in 2004. Since 2007, he is Principal Investigator at CARIM. In 2011, he was appointed Professor of Cardiac Electrophysiology and became chairman of the Department of Physiology in 2019.

His research interests include cellular and integrated actions of antiarrhythmic drugs, the development of substrates for the perpetuation of atrial fibrillation, invasive and non-invasive quantification of the substrate of atrial fibrillation, interaction between atrial fibrillation and activation of the coagulation system, and three-dimensional computer models of atrial fibrillation. He is coordinator of the CVON network RACE V and PI in numerous national and international research networks. He was member of the European task force for the development of the ESC guidelines for management of atrial fibrillation in 2010, 2012, and 2016. Furthermore, he is member of the Executive Committee of the Network of Competence for Atrial Fibrillation (AFNET), co-founder of the Maastricht University spin-off company YourRhythmics BV, and acts as the chairman of the Strategic board of CARIM.

Department of Physiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 3.130
T: +31(0)43 388 12 00

  • 2024
    • Hutschalik, T., Özgül, O., Casini, M., Szabó, B., Peyronnet, R., Bártulos, Ó., Argenziano, M., Schotten, U., & Matsa, E. (2024). Immune response caused by M1 macrophages elicits atrial fibrillation-like phenotypes in coculture model with isogenic hiPSC-derived cardiomyocytes. Stem Cell Research & Therapy, 15(1), Article 280. https://doi.org/10.1186/s13287-024-03814-0
    • Schnabel, R. B., Benezet-Mazuecos, J., Becher, N., McIntyre, W. F., Fierenz, A., Lee, S. F., Goette, A., Atar, D., Bertaglia, E., Benz, A. P., Chlouverakis, G., Birnie, D. H., Dichtl, W., Blomstrom-Lundqvist, C., Camm, A. J., Erath, J. W., Simantirakis, E., Kutyifa, V., Lip, G. Y. H., ... Kirchhof, P. (2024). Anticoagulation in device-detected atrial fibrillation with or without vascular disease: a combined analysis of the NOAH-AFNET 6 and ARTESiA trials. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae596
    • Fabritz, L., Al-Taie, C., Borof, K., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Roth Cardoso, V., Chua, W., van Elferen, S., Eckardt, L., Gkoutos, G., Goette, A., Guasch, E., Hatem, S., Metzner, A., Mont, L., Murukutla, V. A., Obergassel, J., Rillig, A., ... Kirchhof, P. (2024). Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae611
    • Diener, H. C., Becher, N., Sehner, S., Toennis, T., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G.-A., Dichtl, W., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lip, G. Y. H., Lubinski, A., ... NOAH-AFNET 6 investigators (2024). Anticoagulation in Patients With Device-Detected Atrial Fibrillation With and Without a Prior Stroke or Transient Ischemic Attack: The NOAH-AFNET 6 Trial. Journal of the American Heart Association, 13(17), e036429. https://doi.org/10.1161/JAHA.124.036429
    • Reyat, J. S., Sommerfeld, L. C., O'Reilly, M., Cardoso, V. R., Thiemann, E., Khan, A. O., O'Shea, C., Harder, S., Müller, C., Barlow, J., Stapley, R. J., Chua, W., Kabir, S. N., Grech, O., Hummel, O., Hübner, N., Kääb, S., Mont, L., Hatem, S. N., ... Fabritz, L. (2024). PITX2 deficiency leads to atrial mitochondrial dysfunction. Cardiovascular Research. Advance online publication. https://doi.org/10.1093/cvr/cvae169
    • Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2024). Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.08.014
    • Goette, A., Corradi, D., Dobrev, D., Aguinaga, L., Cabrera, J.-A., Chugh, S. S., de Groot, J. R., Soulat-Dufour, L., Fenelon, G., Hatem, S. N., Jalife, J., Lin, Y.-J., Lip, G. Y. H., Marcus, G. M., Murray, K. T., Pak, H.-N., Schotten, U., Takahashi, N., Yamaguchi, T., ... Nattel, S. (2024). Atrial Cardiomyopathy Revisited - Evolution of a Concept. A Clinical Consensus Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Association (APHRS), and the Latin American Heart Rhythm Society (LAHRS). EP Europace. Advance online publication. https://doi.org/10.1093/europace/euae204
    • van Hunnik, A., Sobota, V., Zeemering, S., Opacic, D., Scaf, B., D'Alessandro, E., Oyaert, K., Kuiper, M., Diness, J. G., Sorensen, U. S., Milnes, J. T., van der Heyden, M. A. G., Jespersen, T., Schotten, U., & Verheule, S. (2024). Analysis of drug-induced and spontaneous cardioversions reveals similar patterns leading to termination of atrial fibrillation. Frontiers in physiology, 15, Article 1399037. https://doi.org/10.3389/fphys.2024.1399037
    • Winters, J., Kawczynski, M. J., Gilbers, M. D., Isaacs, A., Zeemering, S., Bidar, E., Maesen, B., Rienstra, M., van Gelder, I., Verheule, S., Maessen, J. G., & Schotten, U. (2024). Circulating BMP10 Levels Associate With Late Postoperative Atrial Fibrillation and Left Atrial Endomysial Fibrosis. JACC: Clinical Electrophysiology, 10(7), 1326-1340. https://doi.org/10.1016/j.jacep.2024.03.003
    • Ayagama, T., Charles, P. D., Bose, S. J., Boland, B., Priestman, D. A., Aston, D., Berridge, G., Fischer, R., Cribbs, A. P., Song, Q., Mirams, G. R., Amponsah, K., Heather, L., Galione, A., Herring, N., Kramer, H., Capel, R. A., Platt, F. M., Schotten, U., ... Burton, R. A. B. (2024). Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation. iScience, 27(6), Article 109609. https://doi.org/10.1016/j.isci.2024.109609
    • Bijvoet, G. P., Hermans, B. J. M., Linz, D., Luermans, J. G. L. M., Maesen, B., Nijveldt, R., Mihl, C., Vernooy, K., Wildberger, J. E., Holtackers, R. J., Schotten, U., & Chaldoupi, S.-M. (2024). Optimal Threshold and Interpatient Variability in Left Atrial Ablation Scar Assessment by Dark-Blood LGE CMR. JACC: Clinical Electrophysiology. Advance online publication. https://doi.org/10.1016/j.jacep.2024.05.017
    • Frausing, M. H. J. P., van de Lande, M., Linz, D., Crijns, H. J. G. M., Tieleman, R. G., Hemels, M. E. W., De Melis, M., Schotten, U., Kronborg, M. B., Nielsen, J. C., Van Gelder, I., & Rienstra, M. (2024). Healthcare utilisation and quality of life according to atrial fibrillation burden, episode frequency and duration. Heart. Advance online publication. https://doi.org/10.1136/heartjnl-2024-324016
    • Rillig, A., Eckardt, L., Borof, K., Camm, A. J., Crijns, H. J. G. M., Goette, A., Breithardt, G., Lemoine, M. D., Metzner, A., Rottner, L., Schotten, U., Vettorazzi, E., Wegscheider, K., Zapf, A., Heidbuchel, H., Willems, S., Fabritz, L., Schnabel, R. B., Magnussen, C., & Kirchhof, P. (2024). Safety and efficacy of long-term Sodium Channel Blocker therapy for Early Rhythm Control: The EAST-AFNET 4 trial. EP Europace, 26(6), Article euae121. https://doi.org/10.1093/europace/euae121
    • Lip, G. Y. H., Nikorowitsch, J., Sehner, S., Becher, N., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G.-A., Dichtl, W., Diener, H. C., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lubinski, A., ... NOAH-AFNET 6 investigators (2024). Oral anticoagulation in device-detected atrial fibrillation: effects of age, sex, cardiovascular comorbidities, and kidney function on outcomes in the NOAH-AFNET 6 trial. European Heart Journal, 45(19), 1733-1737. Article ehae225. https://doi.org/10.1093/eurheartj/ehae225
    • Fabritz, L., Chua, W., Cardoso, V. R., Al-Taie, C., Borof, K., Suling, A., Krause, L., Kany, S., Magnussen, C., Wegscheider, K., Breithardt, G., Crijns, H. J. G. M., Camm, A. J., Gkoutos, G., Ellinor, P. T., Goette, A., Schotten, U., Wienhues-Thelen, U.-H., Zeller, T., ... Kirchhof, P. (2024). Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study. Cardiovascular Research, 120(8), 855-868. https://doi.org/10.1093/cvr/cvae067
    • Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2024). Clinical Predictors of Device-Detected Atrial Fibrillation During 2.5 Years After Cardiac Surgery: Prospective RACE V Cohort. JACC: Clinical Electrophysiology, 10(5), 941-955. https://doi.org/10.1016/j.jacep.2024.01.013
    • Linz, D., Andrade, J. G., Arbelo, E., Boriani, G., Breithardt, G., Camm, A. J., Caso, V., Nielsen, J. C., De Melis, M., De Potter, T., Dichtl, W., Diederichsen, S. Z., Dobrev, D., Doll, N., Duncker, D., Dworatzek, E., Eckardt, L., Eisert, C., Fabritz, L., ... Kirchhof, P. (2024). Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference. EP Europace, 26(4), Article euae070. https://doi.org/10.1093/europace/euae070
    • Farnir, F., Chaldoupi, S.-M., Farnir, F., Schotten, U., Vernooy, K., Luermans, J., & Linz, D. (2024). Focal point-by-point biphasic monopolar pulsed field ablation for posterior wall isolation. EP Europace, 26(4), Article euae077. https://doi.org/10.1093/europace/euae077
    • Becher, N., Toennis, T., Bertaglia, E., Blomström-Lundqvist, C., Brandes, A., Cabanelas, N., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G.-A., Dichtl, W., Diener, H. C., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A. N. L., Lip, G. Y. H., Lubinski, A., Marijon, E., ... NOAH-AFNET 6 investigators (2024). Anticoagulation with edoxaban in patients with long atrial high-rate episodes ≥24 h. European Heart Journal, 45(10), 837-849. Article ehad771. https://doi.org/10.1093/eurheartj/ehad771
    • Gonçalves Marques, V., Gharaviri2, A., Özgül, O., Pezzuto, S., Auricchio, A., Bonizzi, P., Zeemering, S., & Schotten, U. (2024). A novel sequential endocardial mapping strategy for locating atrial fibrillation sources based on repetitive conduction patterns: An in-silico study. Journal of Molecular and Cellular Cardiology Plus, 7, Article 100065. https://doi.org/10.1016/j.jmccpl.2024.100065
    • Hermans, B., Özgül, O., Wolf, M., Gonçalves Marques, V., van Hunnik, A., Verheule, S., Chaldoupi, M., Linz, D., El Haddad, M., Duytschaever, M., Bonizzi, P., Vernooy, K., Knecht, S., Zeemering, S., & Schotten, U. (2024). Selecting repetitive focal and rotational activation patterns with the highest probability of being a source of atrial fibrillation. Journal of Molecular and Cellular Cardiology Plus, 7, Article 100064. https://doi.org/10.1016/j.jmccpl.2024.100064
    • Chua, W., Khashaba, A., Canagarajah, H., Nielsen, J. C., di Biase, L., Haeusler, K. G., Hindricks, G., Mont, L., Piccini, J., Schnabel, R. B., Schotten, U., Wienhues-Thelen, U.-H., Zeller, T., Fabritz, L., & Kirchhof, P. (2024). Disturbed atrial metabolism, shear stress, and cardiac load AF after ablation: AXAFA biomolecule study. EP Europace, 26(2), Article euae028. https://doi.org/10.1093/europace/euae028
    • Ozgul, O., Marques, V. G., Hermans, B. JM., van Hunnik, A., Verheule, S., Gharaviri, A., Pezzuto, S., Auricchio, A., Schotten, U., Bonizzi, P., & Zeemering, S. (2024). High-density and high-coverage composite atrial activation maps: an in-silico validation study. Ieee Transactions on Biomedical Engineering. Advance online publication. https://doi.org/10.1109/TBME.2024.3439502
  • 2023
    • Mulder, B. A., Khalilian Ekrami, N., Van De Lande, M. E., Nguyen, B.-O., Weberndorfer, V., Crijns, H. J., Geelhoed, B., Blaauw, Y., Hemels, M. E., Tieleman, R. G., Scheerder, C. O., De Melis, M., Schotten, U., Linz, D., Van Gelder, I. C., & Rienstra, M. (2023). Women have less progression of paroxysmal atrial fibrillation: data from the RACE V study. Open Heart, 10(2), Article e002534. https://doi.org/10.1136/openhrt-2023-002534
    • Kirchhof, P., Schotten, U., & Zapf, A. (2023). Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes. Reply. New England Journal of Medicine, 389(24), 2302-2303. https://doi.org/10.1056/NEJMc2312837
    • Haeusler, K. G., Eichner, F. A., Heuschmann, P. U., Fiebach, J. B., Engelhorn, T., Callans, D., De Potter, T., Debruyne, P., Scherr, D., Hindricks, G., Al-Khalidi, H. R., Mont, L., Kim, W. Y., Piccini, J. P., Schotten, U., Themistoclakis, S., Di Biase, L., & Kirchhof, P. (2023). Detection of brain lesions after catheter ablation depends on imaging criteria - Insights from AXAFA-AFNET 5 trial. EP Europace, 25(12), Article euad323. https://doi.org/10.1093/europace/euad323
    • Young, W. J., Haessler, J., Benjamins, J. W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T. V., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., ... Et al. (2023). Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature Communications, 14(1), Article 1411. https://doi.org/10.1038/s41467-023-36997-w
    • Hermans, B. J. M., Bijvoet, G. P., Holtackers, R. J., Mihl, C., Luermans, J. G. L. M., Maesen, B., Vernooy, K., Linz, D., Chaldoupi, S. M., & Schotten, U. (2023). Multi-modal characterization of the left atrium by a fully automated integration of pre-procedural cardiac imaging and electro-anatomical mapping. IJC Heart and Vasculature, 49(1), Article 101276. https://doi.org/10.1016/j.ijcha.2023.101276
    • Hereijgers, M. J. M., van der Velden, R. M. J., el Moussaoui, N., Verhaert, D. V. M., Habibi, Z., Luermans, J., den Uijl, D., Chaldoupi, S. M., Vernooy, K., Schotten, U., Baumert, M., Gietema, H. A., Mihl, C., Koltowski, L., Franssen, F. M. E., Simons, S. O., & Linz, D. (2023). Repurposing catheter ablation work-up to detect expiratory airflow limitation in patients with atrial fibrillation. IJC Heart and Vasculature, 49(1), Article 101305. https://doi.org/10.1016/j.ijcha.2023.101305
    • Winters, J., Isaacs, A., Zeemering, S., Kawczynski, M., Maesen, B., Maessen, J., Bidar, E., Boukens, B., Hermans, B., van Hunnik, A., Casadei, B., Fabritz, L., Chua, W., Sommerfeld, L., Guasch, E., Mont, L., Batlle, M., Hatem, S., Kirchhof, P., ... Schotten, U. (2023). Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium. Journal of the American Heart Association, 12(22), Article e031220. https://doi.org/10.1161/JAHA.123.031220
    • Chua, W., Cardoso, V. R., Guasch, E., Sinner, M. F., Al-Taie, C., Brady, P., Casadei, B., Crijns, H. J. G. M., Dudink, E. A. M. P., Hatem, S. N., Kääb, S., Kastner, P., Mont, L., Nehaj, F., Purmah, Y., Reyat, J. S., Schotten, U., Sommerfeld, L. C., Zeemering, S., ... Fabritz, L. (2023). An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions. Scientific Reports, 13(1), Article 16743. https://doi.org/10.1038/s41598-023-42331-7
    • Carstensen, H., Nissen, S. D., Saljic, A., Hesselkilde, E. M., van Hunnik, A., Hohl, M., Sattler, S. M., Flogstad, C., Hopster-Iversen, C., Verheule, S., Bohm, M., Schotten, U., Jespersen, T., & Buhl, R. (2023). Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses. Journal of Cardiovascular Translational Research, 16(5), 1205-1219. https://doi.org/10.1007/s12265-023-10378-6
    • Frausing, M. H. J. P., van de Lande, M. E., Maass, A. H., Nguyen, B. O., Hemels, M. E. W., Tieleman, R. G., Koldenhof, T., De Melis, M., Linz, D., Schotten, U., Weberndoerfer, V., Crijns, H. J. G. M., Van Gelder, I. C., Nielsen, J. C., & Rienstra, M. (2023). Brady- and tachyarrhythmias detected by continuous rhythm monitoring in paroxysmal atrial fibrillation. Heart, 109(17), 1286-1293. https://doi.org/10.1136/heartjnl-2022-322253
    • Verhaert, D. V. M., Linz, D., Wassink, G. F., Weijs, B., Philippens, S., Luermans, J. G. L. M., Westra, S. W., Schotten, U., Vernooy, K., & den Uijl, D. W. (2023). A new efficient and integrated pathway for patient evaluation prior to atrial fibrillation ablation. European Journal of Cardiovascular Nursing, 22(5), 498-505. https://doi.org/10.1093/eurjcn/zvac095
    • van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B.-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383(1), 159-165. https://doi.org/10.1016/j.ijcard.2023.04.024
    • Ozgul, O., Hermans, B. JM., van Hunnik, A., Verheule, S., Schotten, U., Bonizzi, P., & Zeemering, S. (2023). High-density and high coverage composite mapping of repetitive atrial activation patterns. Computers in Biology and Medicine, 159(1), Article 106920. https://doi.org/10.1016/j.compbiomed.2023.106920
    • Rijks, J. H. J., Lankveld, T., Manusama, R., Broers, B., van Stipdonk, A. M. W., Chaldoupi, S. M., ter Bekke, R. M. A., Schotten, U., Linz, D., Luermans, J. G. L. M., & Vernooy, K. (2023). Left Bundle Branch Area Pacing and Atrioventricular Node Ablation in a Single-Procedure Approach for Elderly Patients with Symptomatic Atrial Fibrillation. Journal of Clinical Medicine, 12(12), Article 4028. https://doi.org/10.3390/jcm12124028
    • Betz, K., Verhaert, D. V. M., Gawalko, M., Hermans, A. N. L., Habibi, Z., Pluymaekers, N. A. H. A., van der Velden, R. M. J., Homberg, M., Philippens, S., Hereijgers, M. J. M., Vorstermans, B., Simons, S. O., den Uijl, D. W., Chaldoupi, S. M., Luermans, J. G. L. M., Westra, S. W., Lankveld, T., van Steenwijk, R. P., Hol, B., ... Linz, D. (2023). Atrial fibrillation-specific refinement of the STOP-Bang sleep apnoea screening questionnaire: insights from the Virtual-SAFARI study. Clinical research in cardiology, 112(6), 834-845. https://doi.org/10.1007/s00392-023-02157-9
    • Ganesan, P., Deb, B., Feng, R. B., Rodrigo, M., Ruiperez-Campillo, S., Rogers, A. J., Clopton, P., Wang, P. J., Zeemering, S., Schotten, U., Rappel, W. J., & Narayan, S. M. (2023). Quantifying a spectrum of clinical response in atrial tachyarrhythmias using spatiotemporal synchronization of electrograms. EP Europace, 25(5), Article euad055. https://doi.org/10.1093/europace/euad055
    • van de Lande, M. E., Rama, R. S., Koldenhof, T., Arita, V. A., Nguyen, B. O., van Deutekom, C., Weberndorfer, V., Crijns, H. J. G. M., Hemels, M. E. W., Tieleman, R. G., de Melis, M., Schotten, U., Linz, D., Van Gelder, I. C., Rienstra, M., & RACE V Investigators (2023). Time of onset of atrial fibrillation and atrial fibrillation progression data from the RACE V study. EP Europace, 25(5), Article euad058. https://doi.org/10.1093/europace/euad058
    • Arita, V. A., Van de Lande, M. E., Ekrami, N. K., Nguyen, B. O., Van Melle, J. M., Geelhoed, B., De With, R. R., Weberndorfer, V., Erkuner, O., Hillege, H., Linz, D., Ten Cate, H., Spronk, H. M. H., Koldenhof, T., Tieleman, R. G., Schotten, U., Crijns, H. J. G. M., Van Gelder, I. C., & Rienstra, M. (2023). Clinical utility of the 4S-AF scheme in predicting progression of atrial fibrillation: data from the RACE V study. EP Europace, 25(4), 1323-1331. https://doi.org/10.1093/europace/euac268
    • Nguyen, B. O., Weberndorfer, V., Crijns, H. J. G. M., Geelhoed, B., Ten Cate, H., Spronk, H., Kroon, A., De With, R., Al-Jazairi, M., Maass, A. H., Blaauw, Y., Tieleman, R. G., Hemels, M. E. W., Luermans, J., de Groot, J., Allaart, C. P., Elvan, A., De Melis, M., Scheerder, C., ... Rienstra, M. (2023). Prevalence and determinants of atrial fibrillation progression in paroxysmal atrial fibrillation. Heart, 109(3), 186-194. https://doi.org/10.1136/heartjnl-2022-321027
  • 2022
    • van der Velden, J., Asselbergs, F. W., Bakkers, J., Batkai, S., Bertrand, L., Bezzina, C. R., Bot, I., Brundel, B., Carrier, L., Chamuleau, S., Ciccarelli, M., Dawson, D., Davidson, S. M., Dendorfer, A., Duncker, D. J., Eschenhagen, T., Fabritz, L., Falcão-Pires, I., Ferdinandy, P., ... Thum, T. (2022). Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. Cardiovascular Research, 118(15), 3016-3051. https://doi.org/10.1093/cvr/cvab370
    • Zeemering, S., Isaacs, A., Winters, J., Maesen, B., Bidar, E., Dimopoulou, C., Guasch, E., Batlle, M., Haase, D., Hatem, S. N., Kara, M., Kääb, S., Mont, L., Sinner, M. F., Wakili, R., Maessen, J., Crijns, H. J. G. M., Fabritz, L., Kirchhof, P., ... Schotten, U. (2022). Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Heart Rhythm, 19(12), 2115-2124. https://doi.org/10.1016/j.hrthm.2022.08.019
    • Fabritz, L., Connolly, D. L., Czarnecki, E., Dudek, D., Guasch, E., Haase, D., Huebner, T., Zlahoda-Huzior, A., Jolly, K., Kirchhof, P., Obergassel, J., Schotten, U., Vettorazzi, E., Winkelmann, S. J., Zapf, A., Schnabel, R. B., & Smart in OAC—AFNET 9 investigators (2022). Smartphone and wearable detected atrial arrhythmias in Older Adults: Results of a fully digital European Case finding study. European Heart Journal - Digital Health, 3(4), 610-625. https://doi.org/10.1093/ehjdh/ztac067
    • Cai, M., Schotten, U., Dobrev, D., & Heijman, J. (2022). Atrial fibrillation substrate development before, during and after cardiac surgery: Who is to blame for late post-operative atrial fibrillation?International Journal of Cardiology, 365, 44-46. https://doi.org/10.1016/j.ijcard.2022.07.027
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