Stephane Heymans

Professor

Stephane Heymans is Professor of Cardiomyopathies and Head of the Centre for Heart Failure Research, Department of Cardiology, Maastricht University. He obtained his Medical Degree from the KU Leuven (Belgium) in 1995 and went on to get a PhD in Medical Sciences in 2000, studying the role of proteinases in acute myocardial infarction. In 2003, he joined the Department of Cardiology of Maastricht UMC+ as an academic medical specialist and in 2006 he took over the Multidisciplinary Cardiomyopathy Program (Genetics, Immunology, Microbiology and Pathology departments).

In 2008, he established his independent research laboratory at Cardiovascular Research Institute Maastricht. His research interests focus on the molecular mechanisms of heart failure, looking at the interplay between inflammatory cells, fibroblasts and cardiomyocytes. Particular focus is on the role of non-structural matrix proteins, matrix turnover and non-coding RNAs.

Furthermore, he is Professor of 'Inflammation and Matrix Biology in Cardiomyopathies' at the University of Leuven and he is a board member of the ESC Heart Failure Association, ESC Working Group of Myocardial Function, ESC Heart Failure Association Committee on Diastolic Heart Failure and ESC Heart Failure Association Committee on Translational Research.

Website www.hfresearch.eu

Department of Cardiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: G3.230
T: +31(0)43 388 43 04

  • 2022
    • Tayal, U., Verdonschot, J. A. J., Hazebroek, M. R., Howard, J., Gregson, J., Newsome, S., Gulati, A., Pua, C. J., Halliday, B. P., Lota, A. S., Buchan, R. J., Whiffin, N., Kanapeckaite, L., Baruah, R., Jarman, J. W. E., O'Regan, D. P., Barton, P. J. R., Ware, J. S., Pennell, D. J., ... Prasad, S. K. (2022). Precision Phenotyping of Dilated Cardiomyopathy Using Multidimensional Data. Journal of the American College of Cardiology, 79(22), 2219-2232. https://doi.org/10.1016/j.jacc.2022.03.375
    • Rastogi, T., Ho, F. K., Rossignol, P., Merkling, T., Butler, J., Clark, A., Collier, T., Delles, C., Jukema, J. W., Heymans, S., Latini, R., Mebazaa, A., Pellicori, P., Sever, P., Staessen, J. A., Thijs, L., Cleland, J. G., Sattar, N., Zannad, F., & Girerd, N. (2022). Comparing and contrasting risk factors for Heart failure in patients with and without history of myocardial infarction: Data from HOMAGE and the UK Biobank. European journal of heart failure, 24(6), 976-984. https://doi.org/10.1002/ejhf.2495
    • van de Leur, R. R., Bleijendaal, H., Taha, K., Mast, T., Gho, J. M. I. H., Linschoten, M., van Rees, B., Henkens, M. T. H. M., Heymans, S., Sturkenboom, N., Tio, R. A., Offerhaus, J. A., Bor, W. L., Maarse, M., Haerkens-Arends, H. E., Kolk, M. Z. H., van der Lingen, A. C. J., Selder, J. J., Wierda, E. E., ... CAPACITY-COVID collaborative consortium (2022). Electrocardiogram-based mortality prediction in patients with COVID-19 using machine learning. Netherlands Heart Journal, 30(6), 312-318. https://doi.org/10.1007/s12471-022-01670-2
    • Raafs, A. G., Vos, J. L., Henkens, M. T. H. M., Slurink, B. O., Verdonschot, J. A. J., Bossers, D., Roes, K., Gerretsen, S., Knackstedt, C., Hazebroek, M. R., Nijveldt, R., & Heymans, S. R. B. (2022). Left Atrial Strain Has Superior Prognostic Value to Ventricular Function and Delayed-Enhancement in Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 15(6), 1015-1026. https://doi.org/10.1016/j.jcmg.2022.01.016
    • Henkens, M. T. H. M., van Ommen, A. M., Remmelzwaal, S., Valstar, G. B., Wang, P., Verdonschot, J. A. J., Hazebroek, M. R., Hofstra, L., Empel, V. P. M., Beulens, J. W. J., Ruijter, H. M., & Heymans, S. R. B. (2022). The HFA-PEFF score identifies 'early-HFpEF' phenogroups associated with distinct biomarker profiles. Esc heart failure, 9(3), 2032-2036. https://doi.org/10.1002/ehf2.13861
    • Babu, V. S., Mallipatna, A., Sa, D., Dudeja, G., Kannan, R., Shetty, R., Nair, A. P., Gundimeda, S., Chaurasia, S. S., Verma, N. K., Lakshminarayanan, R., Heymans, S., Barathi, V. A., Guha, N., & Ghosh, A. (2022). Integrated Analysis of Cancer Tissue and Vitreous Humor from Retinoblastoma Eyes Reveals Unique Tumor-Specific Metabolic and Cellular Pathways in Advanced and Non-Advanced Tumors. Cells, 11(10), Article 1668. https://doi.org/10.3390/cells11101668
    • Carai, P., Ruozi, G., Paye, A., Debing, Y., Bortolotti, F., Lecomte, J., Zentilin, L., Jones, E. A. V., Giacca, M., & Heymans, S. (2022). AAV9-mediated functional screening for cardioprotective cytokines in Coxsackievirus-B3-induced myocarditis. Scientific Reports, 12(1), Article 7304. https://doi.org/10.1038/s41598-022-11131-w
    • Coats, A. J. S., Heymans, S., Farmakis, D., Anker, S. D., Backs, J., & Bauersachs, J. (2022). Corrigendum to: Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology (vol 43, pg 863, 2022). European Heart Journal, 43(17), 1635-1635. Article ehac124. https://doi.org/10.1093/eurheartj/ehac124
    • Ferreira, J. P., Verdonschot, J. A. J., Girerd, N., Bozec, E., Pellicori, P., Collier, T., Mariottoni, B., Cosmi, F., Hazebroek, M., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelman, F., Clark, A. L., Díez, J., González, A., Rossignol, P., ... Zannad, F. (2022). Influence of ejection fraction on biomarker expression and response to spironolactone in people at risk of heart failure: findings from the HOMAGE trial. European journal of heart failure, 24(5), 771-778. https://doi.org/10.1002/ejhf.2455
    • Verdonschot, J. A. J., Ferreira, J. P., Pizard, A., Pellicori, P., Brunner La Rocca, H.-P., Clark, A. L., Cosmi, F., Cuthbert, J., Girerd, N., Waring, O. J., Henkens, M. H. T. M., Mariottoni, B., Petutschnigg, J., Rossignol, P., Hazebroek, M. R., Cleland, J. G. F., Zannad, F., Heymans, S. R. B., & HOMAGE “Heart Omics in AGEing” consortium (2022). The Effect of Spironolactone in Patients With Obesity at Risk for Heart Failure: Proteomic Insights from the HOMAGE Trial. Journal of Cardiac Failure, 28(5), 778-786. https://doi.org/10.1016/j.cardfail.2021.12.005
    • Henkens, M. T. H. M., Weerts, J., Verdonschot, J. A. J., Raafs, A. G., Stroeks, S., Sikking, M. A., Amin, H., Mourmans, S. G. J., Geraeds, C. B. G., Sanders-van Wijk, S., Aizpurua, A. B., Uszko-Lencer, N. H. M. K., Krapels, I. P. C., Wolffs, P. F. G., Brunner, H. G., Leeuwen, R. E. W., Verhesen, W., Schalla, S. M., van Stipdonk, A. W. M., ... Heymans, S. R. B. (2022). Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry. Esc heart failure, 9(2), 1463-1470. https://doi.org/10.1002/ehf2.13833
    • Carai, P., Papageorgiou, A. P., Van Linthout, S., Deckx, S., Velthuis, S., Lutgens, E., Wijnands, E., Tschöpe, C., Schmuttermaier, C., Kzhyshkowska, J., Jones, E. A. V., & Heymans, S. (2022). Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis. Journal of Molecular and Cellular Cardiology, 165, 31-39. https://doi.org/10.1016/j.yjmcc.2021.12.009
    • Robinson, E. L., Baker, A. H., Brittan, M., McCracken, I., Condorelli, G., Emanueli, C., Srivastava, K. P., Gaetano, C., Thum, T., Vanhaverbeke, M., Angione, C., Heymans, S., Devaux, Y., Pedrazzini, T., Martelli, F., & EU-CardioRNA COST Action (CA17129) (2022). Dissecting the transcriptome in cardiovascular disease. Cardiovascular Research, 118(4), 1004-1019. https://doi.org/10.1093/cvr/cvab117
    • Raafs, A. G., Boscutti, A., Henkens, M. T. H. M., van den Broek, W. W. A., Verdonschot, J. A. J., Weerts, J., Stolfo, D., Nuzzi, V., Manca, P., Hazebroek, M. R., Knackstedt, C., Merlo, M., Heymans, S. R. B., & Sinagra, G. (2022). Global Longitudinal Strain is Incremental to Left Ventricular Ejection Fraction for the Prediction of Outcome in Optimally Treated Dilated Cardiomyopathy Patients. Journal of the American Heart Association, 11(6), Article e024505. https://doi.org/10.1161/JAHA.121.024505
    • Linschoten, M., Uijl, A., Schut, A., Jakob, C. E. M., Romao, L. R., Bell, R. M., McFarlane, E., Stecher, M., Zondag, A. G. M., van Iperen, E. P. A., Hermans-van Ast, J. F., Lea, N. C., Schaap, J., Jewbali, L. S., Smits, P. C., Patel, R. S., Aujayeb, A., van Smeden, M., Siebelink, H. J., ... Raafs, A. (2022). Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries. European Heart Journal, 43(11), 1104-1120. https://doi.org/10.1093/eurheartj/ehab656
    • Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Linschoten, M., van Smeden, M., Wang, P., van der Hooft, B. H. M., Tieleman, R., Janssen, M. L. F., Ter Bekke, R. M. A., Hazebroek, M. R., van der Horst, I. C. C., Asselbergs, F. W., Magdelijns, F. J. H., Heymans, S. R. B., & CAPACITY-COVID collaborative consortium (2022). Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. BMC Geriatrics, 22(1), Article 184. https://doi.org/10.1186/s12877-021-02673-1
    • Coats, A. J. S., Heymans, S., Farmakis, D., Anker, S. D., Backs, J., Bauersachs, J., de Boer, R. A., Čelutkienė, J., Cleland, J. G. F., Dobrev, D., van Gelder, I. C., von Haehling, S., Hindricks, G., Jankowska, E., Kotecha, D., van Laake, L. W., Lainscak, M., Lund, L. H., Lunde, I. G., ... Ruschitzka, F. (2022). Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology. European Heart Journal, 43(9), 863-867. https://doi.org/10.1093/eurheartj/ehab834
    • Schiattarella, G. G., Alcaide, P., Condorelli, G., Gillette, T. G., Heymans, S., Jones, E. A. V., Kallikourdis, M., Lichtman, A., Marelli-Berg, F., Shah, S., Thorp, E. B., & Hill, J. A. (2022). Immunometabolic Mechanisms of Heart Failure with Preserved Ejection Fraction. Nature cardiovascular research, 1(3), 211-222. https://doi.org/10.1038/s44161-022-00032-w
    • de Boer, R. A., Heymans, S., Backs, J., Carrier, L., Coats, A. J. S., Dimmeler, S., Eschenhagen, T., Filippatos, G., Gepstein, L., Hulot, J. S., Knoll, R., Kupatt, C., Linke, W. A., Seidman, C. E., Tocchetti, C. G., van der Velden, J., Walsh, R., Seferovic, P. M., & Thum, T. (2022). Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC). European journal of heart failure, 24(3), 406-420. https://doi.org/10.1002/ejhf.2414
    • Piepoli, M. F., Adamo, M., Barison, A., Bestetti, R. B., Biegus, J., Böhm, M., Butler, J., Carapetis, J., Ceconi, C., Chioncel, O., Coats, A., Crespo-Leiro, M. G., de Simone, G., Drexel, H., Emdin, M., Farmakis, D., Halle, M., Heymans, S., Jaarsma, T., ... Hoes, A. (2022). Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology. European Journal of Preventive Cardiology, 29(1), 275-300. https://doi.org/10.1093/eurjpc/zwab147
    • Ferreira, J. P., Collier, T., Clark, A. L., Mamas, M. A., Rocca, H.-P. B.-L., Heymans, S., González, A., Ahmed, F. Z., Petutschnigg, J., Mujaj, B., Cuthbert, J., Rouet, P., Pellicori, P., Mariottoni, B., Cosmi, F., Edelmann, F., Thijs, L., Staessen, J. A., Hazebroek, M., ... Zannad, F. (2022). Spironolactone effect on the blood pressure of patients at risk of developing heart failure: an analysis from the HOMAGE trial. European Heart Journal-Cardiovascular Pharmacotherapy, 8(2), 149-156. https://doi.org/10.1093/ehjcvp/pvab031
    • Ravassa, S., Lopez, B., Ferreira, J. P., Girerd, N., Bozec, E., Pellicori, P., Mariottoni, B., Cosmi, F., Hazebroek, M., Verdonschot, J. A. J., Cuthbert, J., Petutschnigg, J., Moreno, M. U., Heymans, S., Staessen, J. A., Pieske, B., Edelmann, F., Clark, A. L., Cleland, J. G. F., ... HOMAGE Trial Committees and Investigators (2022). Biomarker-based assessment of collagen cross-linking identifies patients at risk of heart failure more likely to benefit from spironolactone effects on left atrial remodelling. Insights from the HOMAGE clinical trial. European journal of heart failure, 24(2), 321-331. https://doi.org/10.1002/ejhf.2394
    • Heymans, S., & Cooper, L. T. (2022). Myocarditis after COVID-19 mRNA vaccination: clinical observations and potential mechanisms. Nature Reviews Cardiology, 19(2), 75-77. https://doi.org/10.1038/s41569-021-00662-w
    • Omerovic, E., Citro, R., Bossone, E., Redfors, B., Backs, J., Bruns, B., Ciccarelli, M., Couch, L. S., Dawson, D., Grassi, G., Iacoviello, M., Parodi, G., Schneider, B., Templin, C., Ghadri, J. R., Thum, T., Chioncel, O., Tocchetti, C. G., Van Der Velden, J., ... Lyon, A. R. (2022). Pathophysiology of Takotsubo Syndrome - a joint scientific statement from the Heart Failure Association Takotsubo Syndrome Study Group and Myocardial Function Working Group of the European Society of Cardiology - Part 1: Overview and the central role for catecholamines and sympathetic nervous system. European journal of heart failure, 24(2), 257-273. https://doi.org/10.1002/ejhf.2400
    • Omerovic, E., Citro, R., Bossone, E., Redfors, B., Backs, J., Bruns, B., Ciccarelli, M., Couch, L. S., Dawson, D., Grassi, G., Iacoviello, M., Parodi, G., Schneider, B., Templin, C., Ghadri, J. R., Thum, T., Chioncel, O., Tocchetti, C. G., Van der Velden, J., ... Lyon, A. R. (2022). Pathophysiology of Takotsubo syndrome - a joint scientific statement from the Heart Failure Association Takotsubo Syndrome Study Group and Myocardial Function Working Group of the European Society of Cardiology - Part 2: vascular pathophysiology, gender and sex hormones, genetics, chronic cardiovascular problems and clinical implications. European journal of heart failure, 24(2), 274-286. https://doi.org/10.1002/ejhf.2368
    • McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Bohm, M., Burri, H., Butler, J., Celutkien, J., Chioncel, O., Cleland, J. G. F., Coats, A. J. S., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., ... ESC Scientific Document Group (2022). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. European journal of heart failure, 24(1), 4-131. https://doi.org/10.1002/ejhf.2333
    • Dal Canto, E., Remmelzwaal, S., van Ballegooijen, A. J., Handoko, M. L., Heymans, S., van Empel, V., Paulus, W. J., Nijpels, G., Elders, P., & Beulens, J. W. J. (2022). Diagnostic value of echocardiographic markers for diastolic dysfunction and heart failure with preserved ejection fraction. Heart Failure Reviews, 27(1), 207-218. https://doi.org/10.1007/s10741-020-09985-1
    • Piepoli, M. F., Adamo, M., Barison, A., Bestetti, R. B., Biegus, J., Böhm, M., Butler, J., Carapetis, J., Ceconi, C., Chioncel, O., Coats, A., Crespo-Leiro, M. G., de Simone, G., Drexel, H., Emdin, M., Farmakis, D., Halle, M., Heymans, S., Jaarsma, T., ... Hoes, A. (2022). Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology. European journal of heart failure, 24(1), 143-168. https://doi.org/10.1002/ejhf.2351
    • Weerts, J., Barandiarán Aizpurua, A., Henkens, M. T. H. M., Lyon, A., van Mourik, M. J. W., van Gemert, M. R. A. A., Raafs, A., Sanders-van Wijk, S., Bayés-Genís, A., Heymans, S. R. B., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Lumens, J., van Empel, V. P. M., & Knackstedt, C. (2022). The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 23(1), 74-84. https://doi.org/10.1093/ehjci/jeab222
  • 2021
    • Gadde, S. G. K., Kshirsagar, A., Anegondi, N., Mochi, T. B., Heymans, S., Ghosh, A., & Roy, A. S. (2021). Correlation of Volume of Macular Edema with Retinal Tomography Features in Diabetic Retinopathy Eyes. Journal of Personalized Medicine, 11(12), Article 1337. https://doi.org/10.3390/jpm11121337
    • Gentile, P., Merlo, M., Peretto, G., Ammirati, E., Sala, S., Della Bella, P., Aquaro, G. D., Imazio, M., Potena, L., Campodonico, J., Foa, A., Raafs, A., Hazebroek, M., Brambatti, M., Cercek, A. C., Nucifora, G., Shrivastava, S., Huang, F., Schmidt, M., ... Sinagra, G. (2021). Post-discharge arrhythmic risk stratification of patients with acute myocarditis and life-threatening ventricular tachyarrhythmias. European journal of heart failure, 23(12), 2045-2054. https://doi.org/10.1002/ejhf.2288
    • Ciccarelli, M., Dawson, D., Falcao-Pires, I., Giacca, M., Hamdani, N., Heymans, S., Hooghiemstra, A., Leeuwis, A., Hermkens, D., Tocchetti, C. G., van der Velden, J., Zacchigna, S., & Thum, T. (2021). Reciprocal organ interactions during heart failure: a position paper from the ESC Working Group on Myocardial Function. Cardiovascular Research, 117(12), 2416-2433. https://doi.org/10.1093/cvr/cvab009
    • Stroeks, S. L. V. M., Hellebrekers, D. M. E. I., Claes, G. R. F., Tayal, U., Krapels, I. P. C., Vanhoutte, E. K., van den Wijngaard, A., Henkens, M. T. H. M., Ware, J. S., Heymans, S. R. B., Brunner, H. G., & Verdonschot, J. A. J. (2021). Clinical impact of re-evaluating genes and variants implicated in dilated cardiomyopathy. Genetics in Medicine, 23(11), 2186-2193. https://doi.org/10.1038/s41436-021-01255-1
    • Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., & van Ballegooijen, A. J. (2021). Sex-specific associations of body composition measures with cardiac function and structure after 8 years of follow-up. Scientific Reports, 11(1), Article 21046. https://doi.org/10.1038/s41598-021-00541-x
    • Verdonschot, J. A. J., Henkens, M. T. H. M., Wang, P., Schummers, G., Raafs, A. G., Krapels, I. P. C., van Empel, V., Heymans, S. R. B., Brunner-La Rocca, H.-P., & Knackstedt, C. (2021). A global longitudinal strain cut-off value to predict adverse outcomes in individuals with a normal ejection fraction. Esc heart failure, 8(5), 4343-4345. https://doi.org/10.1002/ehf2.13465
    • Raafs, A., Verdonschot, J., Ferreira, J. P., Wang, P., Collier, T., Henkens, M., Bjorkman, J., Boccanelli, A., Clark, A. L., Delles, C., Diez, J., Gonzalez, A., Girerd, N., Jukema, J. W., Pinet, F., Rossignol, P., Thum, T., Vodovar, N., de Boer, R. A., ... Heymans, S. (2021). Identification of sex-specific biomarkers predicting new-onset heart failure. Esc heart failure, 8(5), 3512-3520. https://doi.org/10.1002/ehf2.13476
    • McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Bohm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J. G. F., Coats, A. J. S., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., ... ESC Scientific Document Group (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 42(36), 3599-3726. https://doi.org/10.1093/eurheartj/ehab368
    • Verdonschot, J. A. J., Ferreira, J. P., Pellicori, P., Brunner-La Rocca, H. P., Clark, A. L., Cosmi, F., Cuthbert, J., Girerd, N., Mariottoni, B., Petutschnigg, J., Rossignol, P., Cleland, J. G. F., Zannad, F., Heymans, S. R. B., & HOMAGE “Heart Omics in AGEing” consortium (2021). Proteomic mechanistic profile of patients with diabetes at risk of developing heart failure: insights from the HOMAGE trial. Cardiovascular Diabetology, 20(1), Article 163. https://doi.org/10.1186/s12933-021-01357-9
    • Russcher, A., Verdonschot, J., Molenaar-de Backer, M. W. A., Heymans, S. R. B., Kroes, A. C. M., & Zaaijer, H. L. (2021). Parvovirus B19 DNA detectable in hearts of patients with dilated cardiomyopathy, but absent or inactive in blood. Esc heart failure, 8(4), 2723-2730. https://doi.org/10.1002/ehf2.13341
    • Breuls, N., Giarratana, N., Yedigaryan, L., Garrido, G. M., Carai, P., Heymans, S., Ranga, A., Deroose, C., & Sampaolesi, M. (2021). Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner. Cell Death & Disease, 12(7), Article 677. https://doi.org/10.1038/s41419-021-03936-w
    • Tayal, U., Ware, J. S., Lakdawala, N. K., Heymans, S., & Prasad, S. K. (2021). Understanding the genetics of adult-onset dilated cardiomyopathy: what a clinician needs to know. European Heart Journal, 42(24), 2384-2396. https://doi.org/10.1093/eurheartj/ehab286
    • Favere, K., Bosman, M., Klingel, K., Heymans, S., Van Linthout, S., Delputte, P. L., De Sutter, J., Heidbuchel, H., & Guns, P. J. (2021). Toll-Like Receptors: Are They Taking a Toll on the Heart in Viral Myocarditis?Viruses, 13(6), Article 1003. https://doi.org/10.3390/v13061003
    • Raafs, A. G., Verdonschot, J. A. J., Henkens, M. T. H. M., Adriaans, B. P., Wang, P., Derks, K., Abdul Hamid, M. A., Knackstedt, C., van Empel, V. P. M., Diez, J., Brunner-La Rocca, H.-P., Brunner, H. G., Gonzalez, A., Bekkers, S. C. A. M., Heymans, S. R. B., & Hazebroek, M. R. (2021). The combination of carboxy-terminal propeptide of procollagen type I blood levels and late gadolinium enhancement at cardiac magnetic resonance provides additional prognostic information in idiopathic dilated cardiomyopathy - A multilevel assessment of myocardial fibrosis in dilated cardiomyopathy. European journal of heart failure, 23(6), 933-944. https://doi.org/10.1002/ejhf.2201
    • Roblain, Q., Louis, T., Yip, C., Baudin, L., Struman, I., Caolo, V., Lambert, V., Lecomte, J., Noel, A., & Heymans, S. (2021). Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization. Aging, 13(9), 12359-12377. https://doi.org/10.18632/aging.203035
    • Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Zhang, Z., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., Thijs, L., Staessen, J. A., & van Ballegooijen, A. J. (2021). Sex differences in the longitudinal relationship of low-grade inflammation and echocardiographic measures in the Hoorn and FLEMENGHO Study. PLOS ONE, 16(5), Article e0251148. https://doi.org/10.1371/journal.pone.0251148
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