Jos Maessen

Professor

Prof. Jos Maessen joined a young Maastricht University community in 1978 and stayed there after graduation in Medicine, obtaining his PhD, and being trained as a cardiothoracic surgeon, to become professor and chief of the Department of Cardiothoracic surgery as well as Principal Investigator in CARIM in 2005. From a rather non-academic clinical department, his group turned into an important clinical partner for basic scientists within CARIM initiating and supporting many translational research projects. Apart from delivering the best possible care his team is convinced that this approach is the best and shortest way to innovate the cardiac surgical profession. Crossing borders leads to new opportunities. Surgeons and electrophysiologists developed hybrid treatment modalities for AF treatment with better results and new research opportunities. Similarly, in reconstructive surgery of the aorta and mitral valve, combining treatment with virtual reality, modeling and experimental imaging, outcome improved and the results raised new hypotheses for basis research.

Department of Cardiothoracic Surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.C2.023
T: +31(0)43 387 11 25

  • 2014
    • Hazebroek, M. R., van Paassen, P., Weerwind, P. W., Cooper, L. T. . J., Uriel, N., Caliskan, K., de Vries, B., Maessen, J. G., Autschbach, R., Heymans, S., & Donker, D. W. (2014). A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. International Journal of Cardiology, 170(3), E74-E75. https://doi.org/10.1016/j.ijcard.2013.11.028
    • Pison, L., Gelsomino, S., Luca, F., Parise, O., Maessen, J. G., Crijns, H. J. G. M., & La Meir, M. (2014). Effectiveness and safety of simultaneous hybrid thoracoscopic and endocardial catheter ablation of lone atrial fibrillation. Annals of Cardiothoracic Surgery, 3(1), 38-44. https://doi.org/10.3978/j.issn.2225-319X.2013.12.10
    • Simons, A. P., Lindelauf, A. A. M. A., Ganushchak, Y. M., Maessen, J. G., & Weerwind, P. W. (2014). Efficacy and safety of strategies to preserve stable extracorporeal life support flow during simulated hypovolemia. Perfusion, 29(1), 18-24. https://doi.org/10.1177/0267659113502833
    • van Middendorp, L. B., Strik, M., Houthuizen, P., Kuiper, M., Maessen, J. G., Auricchio, A., & Prinzen, F. W. (2014). Electrophysiological and Hemodynamic Effects of Vernakalant and Flecainide During Cardiac Resynchronization in Dyssynchronous Canine Hearts. Journal of Cardiovascular Pharmacology, 63(1), 25-32. https://doi.org/10.1097/FJC.0000000000000020
    • Gelsomino, S., Luca, F., Rao, C. M., Parise, O., Pison, L., Wellens, F., Maessen, J., & La Meir, M. (2014). Improvement of left atrial function and left atrial reverse remodeling after surgical treatment of atrial fibrillation. Annals of Cardiothoracic Surgery, 3(1), 70-4. https://doi.org/10.3978/j.issn.2225-319X.2013.12.03
    • Kumar, N., Timmermans, C., Das, M., Dassen, W., Philippens, S., Maessen, J., & Crijns, H. (2014). Hemoptysis after cryoablation for atrial fibrillation: truth or just a myth?Chest, 146(5). https://doi.org/10.1378/chest.14-1600
    • Nijs, J., Gelsomino, S., Luca, F., Parise, O., Maessen, J., & La Meir, M. (2014). Unreliability of aortic size index to predict risk of aortic dissection in a patient with Turner syndrome. World Journal of Cardiology , 6(5). https://doi.org/10.4330/wjc.v6.i5.349
  • 2013
    • Verberkmoes, N. J., Mokhles, M. M., Bramer, S., van Straten, A. H. M., ter Woorst, J. F., Maessen, J. G., & Berreklouw, E. (2013). Long-Term Clinical Outcome of the Symmetry Aortic Connector System in Off-Pump Coronary Artery Bypass Grafting. Thoracic and Cardiovascular Surgeon, 61(8), 669-675. https://doi.org/10.1055/s-0032-1311539
    • Nuis, R.-J., Sinning, J.-M., Rodes-Cabau, J., Gotzmann, M., van Garsse, L., Kefer, J., Bosmans, J., Yong, G., Dager, A. E., Revilla-Orodea, A., Urena, M., Nickenig, G., Werner, N., Maessen, J., Astarci, P., Perez, S., Benitez, L. M., Amat-Santos, I. J., Lopez, J., ... de Jaegere, P. P. (2013). Prevalence, Factors Associated With, and Prognostic Effects of Preoperative Anemia on Short- and Long-Term Mortality in Patients Undergoing Transcatheter Aortic Valve Implantation. Circulation-Cardiovascular Interventions, 6(6), 625-634. https://doi.org/10.1161/CIRCINTERVENTIONS.113.000409
    • Gelsomino, S., Luca, F., Parise, O., Lorusso, R., Rao, C. M., Vizzardi, E., Gensini, G. F., & Maessen, J. G. (2013). Longitudinal strain predicts left ventricular mass regression after aortic valve replacement for severe aortic stenosis and preserved left ventricular function. Heart and Vessels, 28(6), 775-784. https://doi.org/10.1007/s00380-012-0308-8
    • Weerwind, P. W., van der Veen, F., Gelsomino, S., Nagaraj, N. G., Parise, O., Lorusso, R., Gensini, G. F., & Maessen, J. G. (2013). Cytokine removal on extracorporeal life support for treatment of acute endotoxemia: A randomized controlled animal study. International Journal of Cardiology, 168(5), 4699-4704. https://doi.org/10.1016/j.ijcard.2013.07.175
    • Maesen, B., Zeemering, S., Afonso, C., Eckstein, J., Burton, R. A. B., van Hunnik, A., Stuckey, D. J., Tyler, D., Maessen, J., Grau, V., Verheule, S., Kohl, P., & Schotten, U. (2013). Rearrangement of Atrial Bundle Architecture and Consequent Changes in Anisotropy of Conduction Constitute the 3-Dimensional Substrate for Atrial Fibrillation. Circulation-Arrhythmia and Electrophysiology, 6(5), 967-975. https://doi.org/10.1161/CIRCEP.113.000050
    • van Garsse, L., Gelsomino, S., Luca, F., Parise, O., Lorusso, R., Cheriex, E., Caciolli, S., Vizzardi, E., Rao, C. M., Carella, R., Gensini, G. F., & Maessen, J. (2013). Left ventricular dyssynchrony is associated with recurrence of ischemic mitral regurgitation after restrictive annuloplasty. International Journal of Cardiology, 168(1), 176-184. https://doi.org/10.1016/j.ijcard.2012.09.098
    • La Meir, M., Gelsomino, S., Luca, F., Pison, L., Parise, O., Colella, A., Gensini, G. F., Crijns, H., Wellens, F., & Maessen, J. G. (2013). Minimally invasive surgical treatment of lone atrial fibrillation: Early results of hybrid versus standard minimally invasive approach employing radiofrequency sources. International Journal of Cardiology, 167(4), 1469-1475. https://doi.org/10.1016/j.ijcard.2012.04.044
    • Bramer, S., ter Woorst, F. J., van Geldorp, M. W. A., van den Broek, K. C., Maessen, J. G., Berreklouw, E., & van Straten, A. H. (2013). Does new-onset postoperative atrial fibrillation after coronary artery bypass grafting affect postoperative quality of life?Journal of Thoracic and Cardiovascular Surgery, 146(1), 114-118. https://doi.org/10.1016/j.jtcvs.2012.06.045
    • La Meir, M., Gelsomino, S., Luca, F., Pison, L., Rao, C. M., Wellens, F., & Maessen, J. G. (2013). Improvement of left atrial function and left atrial reverse remodeling after minimally invasive radiofrequency ablation evaluated by 2-dimensional speckle tracking echocardiography. Journal of Thoracic and Cardiovascular Surgery, 146(1), 72-77. https://doi.org/10.1016/j.jtcvs.2012.05.068
    • Bosch, Y., Al Dieri, R., Ten Cate, H., Nelemans, P., Bloemen, S., Hemker, C., Weerwind, P., Maessen, J., & Mochtar, B. (2013). Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article. Journal of Cardiothoracic Surgery, 8. https://doi.org/10.1186/1749-8090-8-154
    • Verberkmoes, N. J., Mokhles, M. M., Bramer, S., Van Straten, A. H. M., Ter Woorst, J. F., Maessen, J. G., & Berreklouw, E. (2013). Clinical outcome of the PAS-Port (R) proximal anastomosis system in off-pump coronary artery bypass grafting in 201 patients. Journal of Cardiovascular Surgery, 54(3), 389-395.
    • Gelsomino, S., Luca, F., Nediani, C., Orlandini, S. Z., Bani, D., Rubino, A. S., Renzulli, A., Lorusso, R., Consolo, A., Lo Cascio, A., Maessen, J., & Gensini, G. F. (2013). Early Hemodynamic and Biochemical Changes in Overloaded Swine Ventricle. Texas Heart Institute Journal, 40(3), 235-245.
    • van Garsse, L., Gelsomino, S., Luca, F., Parise, O., Cheriex, E., Rao, C. M., Gensini, G. F., & Maessen, J. G. (2013). Left atrial strain and strain rate before and following restrictive annuloplasty for ischaemic mitral regurgitation evaluated by two-dimensional speckle tracking echocardiography. European Heart Journal Cardiovascular Imaging, 14(6), 534-543. https://doi.org/10.1093/ehjci/jes206
    • Gelsomino, S., Corradi, D., Lorusso, R., Parise, O., Callegari, S., Macchi, E., Maessen, J., & La Meir, M. (2013). Anatomical basis of minimally invasive epicardial ablation of atrial fibrillation. European Journal of Cardio-Thoracic Surgery, 43(4), 673-682. https://doi.org/10.1093/ejcts/ezs550
    • Gelsomino, S., van Garsse, L., Luca, F., Parise, O., Cheriex, E., Rao, C. M., Gensini, G. F., & Maessen, J. (2013). Left Ventricular Strain in Chronic Ischemic Mitral Regurgitation in Relation to Mitral Tethering Pattern. Journal of the American Society of Echocardiography, 26(4), 370-380.e11. https://doi.org/10.1016/j.echo.2013.01.011
    • Simons, A. P., Ganushchak, Y. M., Teerenstra, S., Bergmans, D. C., Maessen, J. G., & Weerwind, P. W. (2013). Hypovolemia in Extracorporeal Life Support Can Lead to Arterial Gaseous Microemboli. Artificial Organs, 37(3), 276-282. https://doi.org/10.1111/j.1525-1594.2012.01560.x
    • La Meir, M., Gelsomino, S., Luca, F., Pison, L., Colella, A., Lorusso, R., Crudeli, E., Gensini, G. F., Crijns, H. G., & Maessen, J. (2013). Minimal invasive surgery for atrial fibrillation: an updated review. EP Europace, 15(2), 170-182. https://doi.org/10.1093/europace/eus216
  • 2012
    • van Garsse, L., Gelsomino, S., Parise, O., Luca, F., Cheriex, E., Lorusso, R., Vizzardi, E., Rao, C. M., Gensini, G. F., & Maessen, J. (2012). Systolic Papillary Muscle Dyssynchrony Predicts Recurrence of Mitral Regurgitation in Patients with Ischemic Cardiomyopathy (ICM) Undergoing Mitral Valve Repair. Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 29(10), 1191-1200. https://doi.org/10.1111/j.1540-8175.2012.01789.x
    • van Garsse, L., Gelsomino, S., Cheriex, E., Luca, F., Rao, C. M., Parise, O., Gensini, G. F., & Maessen, J. (2012). Tethering Symmetry Reflects Advanced Left Ventricular Mechanical Dyssynchrony in Patients With Ischemic Mitral Regurgitation Undergoing Restrictive Mitral Valve Repair. Annals of Thoracic Surgery, 94(5), 1418-1428. https://doi.org/10.1016/j.athoracsur.2012.05.099
    • Nuis, R.-J., Rodes-Cabau, J., Sinning, J.-M., van Garsse, L., Kefer, J., Bosmans, J., Dager, A. E., van Mieghem, N. M., Urena, M., Nickenig, G., Werner, N., Maessen, J., Astarci, P., Perez, S., Benitez, L. M., Dumont, E., van Domburg, R. T., & de Jaegere, P. (2012). Blood Transfusion and the Risk of Acute Kidney Injury After Transcatheter Aortic Valve Implantation. Circulation-Cardiovascular Interventions, 5(5), 680-688. https://doi.org/10.1161/CIRCINTERVENTIONS.112.971291
    • Houthuizen, P., Van Garsse, L. A. F. M., Poels, T. T., de Jaegere, P., van der Boon, R. M. A., Swinkels, B. M., ten Berg, J. M., van der Kley, F., Schalij, M. J., Baan, J. J., Cocchieri, R., Brueren, G. R. G., van Straten, A. H. M., den Heijer, P., Bentala, M., van Ommen, V., Kluin, J., Stella, P. R., Prins, M. H., ... Prinzen, F. W. (2012). Left Bundle-Branch Block Induced by Transcatheter Aortic Valve Implantation Increases Risk of Death. Circulation, 126(6), 720-728. https://doi.org/10.1161/CIRCULATIONAHA.112.101055
    • Bosch, Y. P. J., Weerwind, P. W., Nelemans, P. J., Maessen, J. G., & Mochtar, B. (2012). An Evaluation of Factors Affecting Activated Coagulation Time. Journal of Cardiothoracic and Vascular Anesthesia, 26(4), 563-568. https://doi.org/10.1053/j.jvca.2012.03.011
    • La Meir, M., Gelsomino, S., Lorusso, R., Luca, F., Pison, L., Parise, O., Wellens, F., Gensini, G. F., & Maessen, J. (2012). The hybrid approach for the surgical treatment of lone atrial fibrillation: One-year results employing a monopolar radiofrequency source. Journal of Cardiothoracic Surgery, 7, 71. https://doi.org/10.1186/1749-8090-7-71
    • Pison, L., La Meir, M., van Opstal, J., Blaauw, Y., Maessen, J., & Crijns, H. J. (2012). Hybrid Thoracoscopic Surgical and Transvenous Catheter Ablation of Atrial Fibrillation. Journal of the American College of Cardiology, 60(1), 54-61. https://doi.org/10.1016/j.jacc.2011.12.055
    • Gelsomino, S., La Meir, M., Luca, F., Lorusso, R., Crudeli, E., Vasquez, L., Gensini, G. F., & Maessen, J. (2012). Treatment of lone atrial fibrillation: a look at the past, a view of the present and a glance at the future. European Journal of Cardio-Thoracic Surgery, 41(6), 1284-1294. https://doi.org/10.1093/ejcts/ezr222
    • Gelsomino, S., Maessen, J. G., van der Veen, F., Livi, U., Renzulli, A., Luca, F., Carella, R., Crudeli, E., Rubino, A., Rostagno, C., Russo, C., Borghetti, V., Beghi, C., De Bonis, M., Gensini, G. F., & Lorusso, R. (2012). Emergency Surgery for Native Mitral Valve Endocarditis: The Impact of Septic and Cardiogenic Shock. Annals of Thoracic Surgery, 93(5), 1469-1476. https://doi.org/10.1016/j.athoracsur.2011.11.025
    • Korver, E. P. J., Ganushchak, Y. M., Simons, A. P., Donker, D. W., Maessen, J. G., & Weerwind, P. W. (2012). Quantification of recirculation as an adjuvant to transthoracic echocardiography for optimization of dual-lumen extracorporeal life support. Intensive Care Medicine, 38(5), 906-909. https://doi.org/10.1007/s00134-012-2534-z
    • van Garsse, L., Gelsomino, S., Luca, F., Lorusso, R., Rao, C. M., Stefano, P., & Maessen, J. (2012). Importance of anterior leaflet tethering in predicting recurrence of ischemic mitral regurgitation after restrictive annuloplasty. Journal of Thoracic and Cardiovascular Surgery, 143(4), S54-S59. https://doi.org/10.1016/j.jtcvs.2011.09.061
    • Maesen, B., Nijs, J., Maessen, J., Allessie, M., & Schotten, U. (2012). Post-operative atrial fibrillation: a maze of mechanisms. EP Europace, 14(2), 159-174. https://doi.org/10.1093/europace/eur208
    • Lorusso, R., Gelsomino, S., Luca, F., De Cicco, G., Bille, G., Carella, R., Villa, E., Troise, G., Vigano, M., Banfi, C., Gazzaruso, C., Gagliardotto, P., Menicanti, L., Formica, F., Paolini, G., Benussi, S., Alfieri, O., Pastore, M., Ferrarese, S., ... Giustina, A. (2012). Type 2 Diabetes Mellitus Is Associated With Faster Degeneration of Bioprosthetic Valve Results From a Propensity Score-Matched Italian Multicenter Study. Circulation, 125(4), 604-614. https://doi.org/10.1161/CIRCULATIONAHA.111.025064
  • 2011
    • Gelsomino, S., van Garsse, L., Luca, F., Lorusso, R., Cheriex, E., Rao, C. M., Caciolli, S., Vizzardi, E., Crudeli, E., Stefano, P., Gensini, G. F., & Maessen, J. (2011). Impact of Preoperative Anterior Leaflet Tethering on the Recurrence of Ischemic Mitral Regurgitation and the Lack of Left Ventricular Reverse Remodeling after Restrictive Annuloplasty. Journal of the American Society of Echocardiography, 24(12), 1365-1375. https://doi.org/10.1016/j.echo.2011.09.015
    • Bramer, S., van Straten, A. H. M., Hamad, M. A. S., van den Broek, K. C., Maessen, J. G., & Berreklouw, E. (2011). New-Onset Postoperative Atrial Fibrillation Predicts Late Mortality After Mitral Valve Surgery. Annals of Thoracic Surgery, 92(6), 2091-2096. https://doi.org/10.1016/j.athoracsur.2011.06.079
    • Bramer, S., van Straten, A. H. M., Hamad, M. A. S., Berreklouw, E., van den Broek, K. C., & Maessen, J. G. (2011). Body mass index predicts new-onset atrial fibrillation after cardiac surgery. European Journal of Cardio-Thoracic Surgery, 40(5), 1185-1190. https://doi.org/10.1016/j.ejcts.2011.02.043
    • Gelsomino, S., Lorusso, R., Livi, U., Masullo, G., Luca, F., Maessen, J., & Gensini, G. F. (2011). Cost and cost-effectiveness of cardiac surgery in elderly patients. Journal of Thoracic and Cardiovascular Surgery, 142(5), 1062-1073. https://doi.org/10.1016/j.jtcvs.2011.02.013
    • Van Garsse, L. A. F. M., Gelsomino, S., van Ommen, V., Luca, F., & Maessen, J. (2011). Emergency Transthoracic Transapical Mitral Valve-in-Valve Implantation. Journal of Interventional Cardiology, 24(5), 474-476. https://doi.org/10.1111/j.1540-8183.2011.00637.x
    • Boulaksil, M., Jungschleger, J. G., Antoons, G., Houtman, M. J. C., de Boer, T. P., Wilders, R., Beekman, J. D. M., Maessen, J. G., van der Hulst, F. F., van der Heyden, M. A. G., van Veen, T. A. B., van Rijen, H. V. M., de Bakker, J. M. T., & Vos, M. (2011). Drug-Induced Torsade de Pointes Arrhythmias in the Chronic AV Block Dog Are Perpetuated by Focal Activity. Circulation-Arrhythmia and Electrophysiology, 4(4), 566-U275. https://doi.org/10.1161/CIRCEP.110.958991
    • Hamers, L. A. C., Linssen, C. F. M., Lance, M. D., Maessen, J. G., Weerwind, P., Winkens, B., Bergmans, D. C. J. J., & van Mook, W. N. K. A. (2011). Positive cultures from cardiopulmonary bypass: prevalence and relevance regarding postoperative infection. European Journal of Cardio-Thoracic Surgery, 40(2), 372-378. https://doi.org/10.1016/j.ejcts.2010.11.063
    • Severdija, E. E., Heijmans, J. H., Theunissen, M., Maessen, J. G., Roekaerts, P. H., & Weerwind, P. W. (2011). Retrograde autologous priming reduces transfusion requirements in coronary artery bypass surgery. Perfusion, 26(4), 315-321. https://doi.org/10.1177/0267659111408379
    • La Meir, M., Gelsomino, S., Luca, F., Pison, L., Chambille, P., Parise, O., Crijns, H. J., & Maessen, J. G. (2011). Time-Related Prevalence of Postoperative Atrial Fibrillation After Stand-Alone Minimally Invasive Radiofrequency Ablation. Journal of Cardiac Surgery, 26(4), 453-459. https://doi.org/10.1111/j.1540-8191.2011.01272.x
    • Bolderman, R. W., Hermans, J. J. R., Rademakers, L. M., de Jong, M. M. J., de Bruin, J. P., Dias, A. A., van der Veen, F. H., & Maessen, J. G. (2011). Epicardial application of an amiodarone-releasing hydrogel to suppress atrial tachyarrhythmias. International Journal of Cardiology, 149(3), 341-346. https://doi.org/10.1016/j.ijcard.2010.02.014
    • van Breugel, N. H., Bidar, E., Essers, B. A., Nieman, F. H., Accord, R. E., Severens, J. L., Vrakking, R., & Maessen, J. G. (2011). Cost-effectiveness of ablation surgery in patients with atrial fibrillation undergoing cardiac surgery. Interactive Cardiovascular and Thoracic Surgery, 12(3), 394-398. https://doi.org/10.1510/icvts.2010.249482
    • Folkeringa, J. R., Tieleman, R. G., Maessen, J. G., Prins, M. H., Nieuwlaat, R., & Crijns, H. J. G. M. (2011). Statins Do Not Reduce Atrial Fibrillation After Cardiac Valvular Surgery: A Single Centre Observational Study. Netherlands Heart Journal, 19(1), 17-23. https://doi.org/10.1007/s12471-010-0055-3
    • Ganushchak, Y. M., Reesink, K. D., Weerwind, P. W., & Maessen, J. G. (2011). The effect of oxygenator mechanical characteristics on energy transfer during clinical cardiopulmonary bypass. Perfusion, 26(1), 39-44. https://doi.org/10.1177/0267659110385606