Jos Maessen

Professor

Prof. Jos Maessen joined a young Maastricht University community in 1978 and stayed there after graduation in Medicine, obtaining his PhD, and being trained as a cardiothoracic surgeon, to become professor and chief of the Department of Cardiothoracic surgery as well as Principal Investigator in CARIM in 2005. From a rather non-academic clinical department, his group turned into an important clinical partner for basic scientists within CARIM initiating and supporting many translational research projects. Apart from delivering the best possible care his team is convinced that this approach is the best and shortest way to innovate the cardiac surgical profession. Crossing borders leads to new opportunities. Surgeons and electrophysiologists developed hybrid treatment modalities for AF treatment with better results and new research opportunities. Similarly, in reconstructive surgery of the aorta and mitral valve, combining treatment with virtual reality, modeling and experimental imaging, outcome improved and the results raised new hypotheses for basis research.

Department of Cardiothoracic Surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.C2.023
T: +31(0)43 387 11 25

  • 2024
    • Sardari Nia, P., Ganushchak, Y., & Maessen, J. (2024). Proposal of statistical twin as transition to full digital twin technology for cardiovascular interventions. Interdisciplinary CardioVascular and Thoracic Surgery. Advance online publication. https://doi.org/10.1093/icvts/ivae032
    • Jung, Y., van Kuijk, S. M. J., Gietema, H., Maessen, J. G., & Sardari Nia, P. (2024). Prediction of poor exposure in endoscopic mitral valve surgery using computed tomography. European Journal of Cardio-Thoracic Surgery, 65(3), Article ezae070. https://doi.org/10.1093/ejcts/ezae070
    • Checheili Sobbi, S., Jung, Y., Fillet, M., Bakhtiary, F., Maessen, J. G., & Sardari Nia, P. (2024). Simulation-based training for endoscopic mitral valve repair: the impact on basic surgical skills for placement of sutures at mitral valve annulus during 2-h training workshop. Interdisciplinary CardioVascular and Thoracic Surgery, 38(2), Article ivae003. https://doi.org/10.1093/icvts/ivae003
    • Heuts, S., van de Koolwijk, A. F., Gabrio, A., Ubben, J. F. H., van der Horst, I. C. C., Delnoij, T. S. R., Suverein, M. M., Maessen, J. G., Lorusso, R., & van de Poll, M. C. G. (2024). Extracorporeal life support in cardiac arrest: a post hoc Bayesian re-analysis of the INCEPTION trial. European Heart Journal: Acute Cardiovascular Care, 13(2), 191-200. Article zuad130. https://doi.org/10.1093/ehjacc/zuad130
    • Ubben, J. F. H., Suverein, M. M., Delnoij, T. S. R., Heuts, S., Winkens, B., Gabrio, A., van der Horst, I. C. C., Maessen, J. G., Lorusso, R., van de Poll, M. C. G., & INCEPTION-investigators (2024). Early extracorporeal CPR for refractory out-of-hospital cardiac arrest - A pre-planned per-protocol analysis of the INCEPTION-trial. Resuscitation, 194, Article 110033. https://doi.org/10.1016/j.resuscitation.2023.110033
  • 2023
    • Suverein, M. M., Maessen, J. G., & van de Poll, M. C. G. (2023). Extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest - current status. Current opinion in critical care, 29(6), 633-639. https://doi.org/10.1097/MCC.0000000000001102
    • Heuts, S., Kawczynski, M., Sardari Nia, P., Maessen, J. G., Biondi-Zoccai, G., & Gabrio, A. (2023). Bayesian interpretation of non-inferiority in transcatheter versus surgical aortic valve replacement trials: a systematic review and meta-analysis. Interdisciplinary CardioVascular and Thoracic Surgery, 37(5), Article ivad185. https://doi.org/10.1093/icvts/ivad185
    • Heuts, S., Gabrio, A., Veenstra, L., Maesen, B., Kats, S., Maessen, J. G., Walton, A. S., Nanayakkara, S., Lansky, A. J., van 't Hof, A. W. J., & Vriesendorp, P. A. (2023). Stroke reduction by cerebral embolic protection devices in transcatheter aortic valve implantation: a systematic review and Bayesian meta-analysis. Heart. Advance online publication. https://doi.org/10.1136/heartjnl-2023-323359
    • Winters, J., Isaacs, A., Zeemering, S., Kawczynski, M., Maesen, B., Maessen, J., Bidar, E., Boukens, B., Hermans, B., van Hunnik, A., Casadei, B., Fabritz, L., Chua, W., Sommerfeld, L., Guasch, E., Mont, L., Batlle, M., Hatem, S., Kirchhof, P., ... Schotten, U. (2023). Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium. Journal of the American Heart Association, 12(22), Article e031220. https://doi.org/10.1161/JAHA.123.031220
    • Kawczynski, M. J., van Kuijk, S. M. J., Olsthoorn, J. R., Maessen, J. G., Kats, S., Bidar, E., & Heuts, S. (2023). Type A aortic dissection: optimal annual case volume for surgery. European Heart Journal, 44(41), 4357-4372. Article ehad551. https://doi.org/10.1093/eurheartj/ehad551
    • Heuts, S., Ceulemans, A., Kuiper, G. J. A. J. M., Schreiber, J. U., van Varik, B. J., Olie, R. H., Ten Cate, H., Maessen, J. G., Milojevic, M., & Maesen, B. (2023). Optimal management of cardiac surgery patients using direct oral anticoagulants: recommendations for clinical practice. European Journal of Cardio-Thoracic Surgery, 64(4), Article ezad340. https://doi.org/10.1093/ejcts/ezad340
    • Coorens, N. A., Daemen, J. H. T., Slump, C. H., Janssen, N., Jansen, Y., Maessen, J. G., Vissers, Y. L. J., Hulsewé, K. W. E., & de Loos, E. R. (2023). Predicting Aesthetic Outcome of the Nuss Procedure in Patients with Pectus Excavatum. Seminars in Thoracic and Cardiovascular Surgery, 35(3), 627-637. https://doi.org/10.1053/j.semtcvs.2022.06.007
    • Scheenstra, B., Bongers, B. C., Broeders, B., Imkamp, M., Van Susante, L., Kietselaer, B., Maessen, J., Van 't Hof, A., & Sardari Nia, P. (2023). Reasons and predictors of non-participation in a personalized digital prehabilitation care trial for patients undergoing elective cardiothoracic surgery. Interdisciplinary CardioVascular and Thoracic Surgery, 37(2), Article ivad123. https://doi.org/10.1093/icvts/ivad123
    • Imran Hamid, U., Modine, T., Maessen, J., van 't Hof, A., Sondergaard, L., Bleiziffer, S., Lancellotti, P., Siepe, M., & Sardari Nia, P. (2023). Structure of multidisciplinary heart teams, a survey based heart team study. Interdisciplinary CardioVascular and Thoracic Surgery, 37(2), Article ivad134. https://doi.org/10.1093/icvts/ivad134
    • Ganizada, B. H., Reesink, K. D., Parikh, S., Ramaekers, M. J. F. G., Akbulut, A. C., Saraber, P. J. M. H., Debeij, G. P., Jaminon, A. M., Natour, E., Lorusso, R., Wildberger, J. E., Mees, B., Schurink, G. W., Jacobs, M. J., Cleutjens, J., Krapels, I., Gombert, A., Maessen, J. G., Accord, R., ... MUMC TAA Student Team (2023). The Maastricht Acquisition Platform for Studying Mechanisms of Cell-Matrix Crosstalk (MAPEX): An Interdisciplinary and Systems Approach towards Understanding Thoracic Aortic Disease. Biomedicines, 11(8), Article 2095. https://doi.org/10.3390/biomedicines11082095
    • Ubben, J. F. H., Heuts, S., Delnoij, T. S. R., Suverein, M. M., van de Koolwijk, A. F., van der Horst, I. C. C., Maessen, J. G., Bartos, J., Kavalkova, P., Rob, D., Yannopoulos, D., Belohlávek, J., Lorusso, R., & van de Poll, M. C. G. (2023). ECPR for refractory OHCA - lessons from 3 randomized controlled trials. The trialists´view. European Heart Journal: Acute Cardiovascular Care, 12(8), 540-547. Article zuad071. https://doi.org/10.1093/ehjacc/zuad071
    • van der Heijden, C. A. J., Weberndörfer, V., Vroomen, M., Luermans, J. G., Chaldoupi, S. M., Bidar, E., Vernooy, K., Maessen, J. G., Pison, L., van Kuijk, S. M. J., La Meir, M., Crijns, H. J. G. M., & Maesen, B. (2023). Hybrid Ablation Versus Repeated Catheter Ablation in Persistent Atrial Fibrillation: A Randomized Controlled Trial. JACC: Clinical Electrophysiology, 9(7), 1013-1023. https://doi.org/10.1016/j.jacep.2022.12.011
    • van der Heijden, C. A. J., Weberndorfer, V., Vroomen, M., Luermans, J. G., Chaldoupi, S.-M., Bidar, E., Vernooy, K., Maessen, J. G., Pison, L., van Kuijk, S. M. J., La Meir, M., Crijns, H. J. G. M., & Maesen, B. (2023). REPLY: Hybrid Ablation for Persistent Atrial Fibrillation: The Approach Matters. JACC: Clinical Electrophysiology, 9(7), 1195-1195. https://doi.org/10.1016/j.jacep.2023.03.018
    • Willers, A., Mariani, S., Maessen, J. M., Lorusso, R., & Swol, J. (2023). Extracorporeal life support in thoracic emergencies-a narrative review of current evidence. Journal of Thoracic Disease, 15(7), 4076-4089. https://doi.org/10.21037/jtd-22-1307
    • Kurniawati, E. R., Weerwind, P. W., & Maessen, J. G. (2023). Understanding lactate and its clearance during extracorporeal membrane oxygenation for supporting refractory cardiogenic shock patients. BMC Cardiovascular disorders, 23(1), Article 305. https://doi.org/10.1186/s12872-023-03221-y
    • Janssen, N., Daemen, J. H. T., Michels, I. L., Franssen, A. J. P. M., Maessen, J. G., Hulsewe, K. W. E., Vissers, Y. L. J., & de Loos, E. R. (2023). Preoperative imaging of clinically relevant intrathoracic abnormalities in pectus excavatum patients. Quantitative Imaging in Medicine and Surgery, 13(6), 3489-3495. https://doi.org/10.21037/qims-22-1366
    • Marcuse, F., Hoeijmakers, J. G. J., Hochstenbag, M., Hamid, M. A., Keijzers, M., Mane-Damas, M., Martinez-Martinez, P., Verschuuren, J., Kuks, J., Beekman, R., van der Kooi, A. J., van Doorn, P., van Es, M., Maessen, J. J. G., & De Baets, M. H. V. (2023). Outcomes after robotic thymectomy in nonthymomatous versus thymomatous patients with acetylcholine-receptor-antibody-associated myasthenia gravis. Neuromuscular Disorders, 33(5), 417-424. https://doi.org/10.1016/j.nmd.2023.03.005
    • Mariani, S., van Bussel, B. C. T., Ravaux, J. M., Roefs, M. M., De Piero, M. E., Di Mauro, M., Willers, A., Segers, P., Delnoij, T., van der Horst, I. C. C., Maessen, J., Lorusso, R., & Netherlands Heart Registration Cardiothoracic Surgery Registration Committee (2023). Variables associated with in-hospital and postdischarge outcomes after postcardiotomy extracorporeal membrane oxygenation: Netherlands Heart Registration Cohort. Journal of Thoracic and Cardiovascular Surgery, 165(3), 1127-1137.e14. https://doi.org/10.1016/j.jtcvs.2022.08.024
    • Parise, O., Parise, G., Vaidyanathan, A., Occhipinti, M., Gharaviri, A., Tetta, C., Bidar, E., Maesen, B., Maessen, J. G., La Meir, M., & Gelsomino, S. (2023). Machine Learning to Identify Patients at Risk of Developing New-Onset Atrial Fibrillation after Coronary Artery Bypass. Journal of Cardiovascular Development and Disease, 10(2), Article 82. https://doi.org/10.3390/jcdd10020082
    • Suverein, M. M., Delnoij, T. S. R., Lorusso, R., Brandon Bravo Bruinsma, G. J., Otterspoor, L., Elzo Kraemer, C. V., Vlaar, A. P. J., Van Der Heijden, J. J., Scholten, E., Den Uil, C., Jansen, T., Van Den Bogaard, B., Kuijpers, M., Lam, K. Y., Montero Cabezas, J. M., Driessen, A. H. G., Rittersma, S. Z. H., Heijnen, B. G., Dos Reis Miranda, D., ... Van De Poll, M. C. G. (2023). Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest. New England Journal of Medicine, 388(4), 299-309. https://doi.org/10.1056/NEJMoa2204511
    • Heuts, S., Gollmann-Tepeköylü, C., Denessen, E. J. S., Olsthoorn, J. R., Romeo, J. L. R., Maessen, J. G., van 't Hof, A. W. J., Bekers, O., Hammarsten, O., Pölzl, L., Holfeld, J., Bonaros, N., van der Horst, I. C. C., Davidson, S. M., Thielmann, M., & Mingels, A. M. A. (2023). Cardiac troponin release following coronary artery bypass grafting: mechanisms and clinical implications. European Heart Journal, 44(2), 100-112. https://doi.org/10.1093/eurheartj/ehac604
    • Daemen, J. H. T., Heuts, S., Rezazadah Ardabili, A., Maessen, J. G., Hulsewé, K. W. E., Vissers, Y. L. J., & de Loos, E. R. (2023). Development of Prediction Models for Cardiac Compression in Pectus Excavatum Based on Three-Dimensional Surface Images. Seminars in Thoracic and Cardiovascular Surgery, 35(1), 202-212. https://doi.org/10.1053/j.semtcvs.2021.11.006
  • 2022
    • Denessen, E. J., Heuts, S., Daemen, J. H., van Doorn, W. P., Vroemen, W. H., Sels, J.-W., Segers, P., Van't Hof, A. W., Maessen, J. G., Bekers, O., Van Der Horst, I. C., & Mingels, A. M. (2022). High-Sensitivity Cardiac Troponin I and T Kinetics Differ following Coronary Bypass Surgery: A Systematic Review and Meta-Analysis. Clinical Chemistry, 68(12), 1564-1575. Article hvac152. https://doi.org/10.1093/clinchem/hvac152
    • Zeemering, S., Isaacs, A., Winters, J., Maesen, B., Bidar, E., Dimopoulou, C., Guasch, E., Batlle, M., Haase, D., Hatem, S. N., Kara, M., Kääb, S., Mont, L., Sinner, M. F., Wakili, R., Maessen, J., Crijns, H. J. G. M., Fabritz, L., Kirchhof, P., ... Schotten, U. (2022). Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Heart Rhythm, 19(12), 2115-2124. https://doi.org/10.1016/j.hrthm.2022.08.019
    • Olsthoorn, J. R., Heuts, S., Houterman, S., Roefs, M., Maessen, J. G., Nia, P. S., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Does concomitant tricuspid valve surgery increase the risks of minimally invasive mitral valve surgery? A multicentre comparison based on data from The Netherlands Heart Registration. Journal of Cardiac Surgery, 37(12), 4362–4370. https://doi.org/10.1111/jocs.17004
    • van der Heijden, C. A. J., Weberndörfer, V., Luermans, J. G. L. M., Chaldoupi, M., van Kuijk, S. M. J., Vroomen, M., Bidar, E., Maessen, J. G., Pison, L., La Meir, M., & Maesen, B. (2022). Hybrid ablation of atrial fibrillation: A unilateral left-sided thoracoscopic approach. Journal of Cardiac Surgery, 37(12), 4630-4638. https://doi.org/10.1111/jocs.17144
    • Daemen, J. H. T., Coorens, N. A., Hulsewé, K. W. E., Maal, T. J. J., Maessen, J. G., Vissers, Y. L. J., & de Loos, E. R. (2022). Three-dimensional Surface Imaging for Clinical Decision Making in Pectus Excavatum. Seminars in Thoracic and Cardiovascular Surgery, 34(4), 1364-1373. https://doi.org/10.1053/j.semtcvs.2021.08.002
    • Yilmaz, A., Van Genechten, S., Claessens, J., Packlé, L., Maessen, J., & Kaya, A. (2022). A totally endoscopic approach for aortic valve surgery. European Journal of Cardio-Thoracic Surgery, 62(6), Article ezac467. https://doi.org/10.1093/ejcts/ezac467
    • van der Heijden, C. A. J., Segers, P., Masud, A., Weberndörfer, V., Chaldoupi, S.-M., Luermans, J. G. L. M., Bijvoet, G. P., Kietselaer, B. L. J. H., van Kuijk, S. M. J., Barenbrug, P. J. C., Maessen, J. G., Bidar, E., & Maesen, B. (2022). Unilateral Left-sided Thoracoscopic Ablation of Atrial Fibrillation Concomitant to Minimally Invasive Bypass Grafting of the Left Anterior Descending Artery. European Journal of Cardio-Thoracic Surgery, 62(5), Article ezac409. https://doi.org/10.1093/ejcts/ezac409
    • Ganizada, B., Heuts, S., Willems, C., Cortenraad, I., Tunnissen, W., Maessen, J. G., Bidar, E., & Natour, E. (2022). Aortic root replacement in severe left ventricular dysfunction: The added value of beating-heart surgery. Journal of Cardiac Surgery, 37(11), 3984-3987. https://doi.org/10.1111/jocs.16879
    • Marcuse, F., Hochstenbag, M., De Baets, M. H. V., Bootsma, G., Maat, A. P. W. M., Hoeijmakers, J. G. J., Keijzers, M., Abdul Hamid, M., De Ruysscher, D., & Maessen, J. G. (2022). Robotic Thymectomy for Thymomas: A Retrospective Follow-up Study in the Netherlands. Annals of Thoracic Surgery, 114(5), 1886-1894. https://doi.org/10.1016/j.athoracsur.2021.09.056
    • Moula, A. I., Romeo, J. L. R., Parise, G., Parise, O., Maessen, J. G., Natour, E., Bidar, E., & Gelsomino, S. (2022). The evolution of arch surgery: Frozen elephant trunk or conventional elephant trunk?Frontiers in Cardiovascular Medicine, 9, Article 1029262. https://doi.org/10.3389/fcvm.2022.999314
    • Scheenstra, B., Bruninx, A., van Daalen, F., Stahl, N., Latuapon, E., Imkamp, M., Ippel, L., Duijsings-Mahangi, S., Smits, D., Townend, D., Bermejo, I., Dekker, A., Hochstenbach, L., Spreeuwenberg, M., Maessen, J., van 't Hof, A., & Kietselaer, B. (2022). Digital Health Solutions to Reduce the Burden of Atherosclerotic Cardiovascular Disease Proposed by the CARRIER Consortium. JMIR Cardio, 6(2), Article e37437. https://doi.org/10.2196/37437
    • Olsthoorn, J. R., Heuts, S., Houterman, S., Maessen, J. G., Nia, P. S., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Minimally invasive approach compared to resternotomy for mitral valve surgery in patients with prior cardiac surgery: retrospective multicentre study based on the Netherlands Heart Registration. European Journal of Cardio-Thoracic Surgery, 62(5), Article ezac420. https://doi.org/10.1093/ejcts/ezac420
    • Kawczynski, M. J., Van De Walle, S., Maesen, B., Isaacs, A., Zeemering, S., Hermans, B., Vernooy, K., Maessen, J. G., Schotten, U., & Bidar, E. (2022). Preoperative P-wave parameters and risk of atrial fibrillation after cardiac surgery: a meta-analysis of 20,201 patients. Interactive Cardiovascular and Thoracic Surgery, 35(4), Article ivac220. https://doi.org/10.1093/icvts/ivac220
    • Ganushchak, Y. M., Kurniawati, E. R., van der Horst, I. C. C., van Kuijk, S. M. J., Weerwind, P. W., Lorusso, R., & Maessen, J. G. (2022). Patterns of oxygen debt repayment in cardiogenic shock patients sustained with extracorporeal life support: A retrospective study. Journal of Critical Care, 71, Article 154044. https://doi.org/10.1016/j.jcrc.2022.154044
    • Kurniawati, E. R., Teerenstra, S., Vranken, N. P. A., Sharma, A. S., Maessen, J. G., & Weerwind, P. W. (2022). Oxygen debt repayment in the early phase of veno-arterial extracorporeal membrane oxygenation: a cluster analysis. BMC Cardiovascular disorders, 22(1), Article 363. https://doi.org/10.1186/s12872-022-02794-4
    • Maesen, B., Verheule, S., Zeemering, S., La Meir, M., Nijs, J., Lumeij, S., Lau, D. H., Granier, M., Crijns, H. J., Maessen, J. G., Dhein, S., & Schotten, U. (2022). Endomysial fibrosis, rather than overall connective tissue content, is the main determinant of conduction disturbances in human atrial fibrillation. EP Europace, 24(6), 1015-1024. https://doi.org/10.1093/europace/euac026
    • Heuts, S., Kawczynski, M. J., Maessen, J. G., & Bidar, E. (2022). Does early surgery result in improved long-term survival compared to watchful waiting in patients with asymptomatic severe aortic regurgitation with preserved ejection fraction?Interactive Cardiovascular and Thoracic Surgery, 35(2). https://doi.org/10.1093/icvts/ivac080
    • Kurniawati, E. R., van Kuijk, S. M. J., Vranken, N. P. A., Maessen, J. G., & Weerwind, P. W. (2022). Efficacy of Veno-Arterial Extracorporeal Life Support in Adult Patients with Refractory Cardiogenic Shock. Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 16, Article 11795484221113988. https://doi.org/10.1177/11795484221113988
    • Mariani, S., De Piero, M. E., Ravaux, J. M., Saelmans, A., Kawczynski, M. J., van Bussel, B. C. T., Di Mauro, M., Willers, A., Swol, J., Kowalewski, M., Li, T., Delnoij, T. S. R., van der Horst, I. C. C., Maessen, J., & Lorusso, R. (2022). Temporary mechanical circulatory support for COVID-19 patients: A systematic review of literature. Artificial Organs, 46(7), 1249-1267. https://doi.org/10.1111/aor.14261
    • Salden, F. C. W. M., Huntjens, P. R., Schreurs, R., Willemen, E., Kuiper, M., Wouters, P., Maessen, J. G., Bordachar, P., Delhaas, T., Luermans, J., Meine, M., Allaart, C. P., van Stipdonk, A. M. W., Prinzen, F. W., Lumens, J., & Vernooy, K. (2022). Pacing therapy for atrioventricular dromotropathy: a combined computational-experimental-clinical study. EP Europace, 24(5), 784-795. https://doi.org/10.1093/europace/euab248
    • Olsthoorn, J. R., Heuts, S., Houterman, S., Maessen, J. G., & Sardari Nia, P. (2022). Effect of minimally invasive mitral valve surgery compared to sternotomy on short- and long-term outcomes: a retrospective multicentre interventional cohort study based on Netherlands Heart Registration. European Journal of Cardio-Thoracic Surgery, 61(5), 1099-1106. https://doi.org/10.1093/ejcts/ezab507
    • Massimi, G., Matteucci, M., Kowalewski, M., Ronco, D., Chiarini, G., De Piero, M. E., Lo Coco, V., Maessen, J. G., Beghi, C., & Lorusso, R. (2022). Operative strategies for acute mitral regurgitation as a mechanical complication of myocardial infarction. Annals of Cardiothoracic Surgery, 11(3), 328-336. https://doi.org/10.21037/acs-2022-ami-0016