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Professorship Julie Staals

Professorship Julie Staals

22 April 2024

Dr Julie Staals (Dept. of Neurology) has been appointed as professor 'Neurovascular disease' as of 1 April 2024.

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ERC Advanced Grant awarded to Prof. Andy Baker

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Prof. Andy Baker (Dept of Pathology) has been awarded a European Research Council (ERC) Advanced Grant of €2,5M for his research project PolymiRize: Poly-miRNA targeting to prevent and reverse complex tissue remodelling after acute cardiovascular events'.

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Carim Maastricht
Carim Maastricht

Amée Buziau

Post doc

Dr Amée Buziau obtained her master’s degree Nutrition and Health at Wageningen University & Research. During her studies, she conducted her bachelor internship at the Human Nutrition Unit at The University of Auckland (New Zealand) and her master internship at the School of Public Health at the University of Queensland (Australia). In 2018, she started her PhD research at CARIM under supervision of Prof. Martijn Brouwers, Prof. Coen Stehouwer, and Prof. Casper Schalkwijk. During her PhD-trajectory, she focused on the role of fructose in the pathogenesis of intrahepatic lipid accumulation, for which she employed multiple research methodologies, including genetic epidemiology (Mendelian randomization), nutritional epidemiology, experiments with humans, and mice experiments.

 

In 2023, Amée was awarded the CARIM Postdoctoral Talent Fellowship to fund the first year of her postdoctoral research. This postdoctoral research was performed at the Stem Cell Institute Leuven (Belgium) in the group of Prof. Catherine Verfaillie. Her postdoctoral research focused on generating human induced pluripotent stem cells (hiPSC) and subsequently differentiating these hiPSC into hepatocytes, to further study the mechanisms of fructose-mediated intrahepatic lipid accumulation in vitro. Subsequently, she was granted a 3-year personal Junior Fellowship from the Dutch Diabetes Foundation to study the role of the pentose-phosphate pathway in the pathogenesis of fructose-mediated intrahepatic lipid accumulation by using hiPSC-derived hepatocytes, large epidemiological studies, and genetic epidemiology (Mendelian randomization).

Ame buziau

Department ofInternal Medicine
Universiteitssingl 60, 6229 ER Maastricht 
PO Box 616, 6200 MD Maastricht

  • 2024
    • Chen, H., Buziau, A. M., Renteria, M. E., Simons, P. I. H. G., & Brouwers, M. C. G. J. (2024). Fructose intake from sugar-sweetened beverages is associated with a greater risk of hyperandrogenism in women: UK Biobank cohort study. European Journal of Endocrinology, 190(1), 104-112. https://doi.org/10.1093/ejendo/lvae006
  • 2023
    • Buziau, A. M., Scheijen, J. L. J. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2023). Effects of fructose added to an oral glucose tolerance test on plasma glucose excursions in healthy adults. Metabolism open, 18(1), Article 100245. https://doi.org/10.1016/j.metop.2023.100245
    • Buziau, A. M., Blokland, G. A. M., Schalkwijk, C. G., Scheijen, J. L. J. M., Simons, P. I. H. G., Eussen, S. J. P. M., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Comment on Lee et al. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies. Diabetes Care 2022;45. Diabetes Care, 46(4), E97-E98. https://doi.org/10.2337/dc22-1930
    • Buziau, A. M., Law, P. J., Blokland, G., Schalkwijk, C., Scheijen, J., Simons, P., van der Kallen, C., Eussen, S., Dagnelie, P. C., van Greevenbroek, M., Houlston, R. S., Wesselius, A., Went, M., Stehouwer, C., & Brouwers, M. C. (2023). Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study. Gut, 72(3), 604-606. https://doi.org/10.1136/gutjnl-2021-326299
  • 2022
    • Buziau, A. M., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., van Dongen, M. C. J. M., Schaper, N. C., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Bekers, O., Meex, S. J. R., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes Care, 45(5), 1116-1123. https://doi.org/10.2337/dc21-2123
  • 2020
    • Buziau, A. M., Scheijen, J. L. J. M., Stehouwer, C. D. A., Simons, N., Brouwers, M. C. G. J., & Schalkwijk, C. G. (2020). Development and validation of a UPLC-MS/MS method to quantify fructose in serum and urine. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1155, Article 122299. https://doi.org/10.1016/j.jchromb.2020.122299
    • Buziau, A. M., Schalkwijk, C. G., Stehouwer, C. D. A., Tolan, D. R., & Brouwers, M. C. G. J. (2020). Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease. Cellular and Molecular Life Sciences, 77(9), 1709-1719. https://doi.org/10.1007/s00018-019-03348-2
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