Coen Stehouwer

Professor

Prof. Coen Stehouwer (born Rotterdam, 1960) obtained an MD at the Erasmus University in Rotterdam (1985; cum laude). He was registered as internist in 1990 and obtained a PhD in 1992 (Vrije Universiteit Medical Centre, Amsterdam). He received postgraduate training in epidemiology and molecular biology. He was appointed professor of medicine and vice-chair of the Department of Medicine in 2000 at the Vrije Universiteit in Amsterdam). In 2004, he accepted a position as professor of medicine and chair of the Department of Medicine at the University of Maastricht. Coen Stehouwer currently is Professor of Internal Medicine and Chair of the Department of Internal Medicine at Maastricht University in the Netherlands.

He is an internationally recognised clinician-scientist in the field of microcirculatory as well as large artery research, notably in the context of cardiovascular complications of diabetes and the metabolic syndrome. Since 1990, the work of Professor Stehouwer and his group has led to 77 completed PhD theses, and more than 800 peer-reviewed papers in international journals.

His work is well-recognised, as shown by a Hirsh index of 109 (Web of Science); >52,000 citations; several awards, such as the Dr F. Gerritzen Award for excellent diabetes research (Dutch Diabetes Research Foundation, 1993); the Castelli-Pedroli Award for excellent research into the complications of diabetes (European Association for the Study of Diabetes, 2005); the Dutch Society of Vascular Medicine Career Award (2007); the Ruitenga Van Swieten honorary professorship of the University of Amsterdam (2009); and the Donald McDonald Award of Artery Society (2017); as well as many invited lectures at (inter)national meetings, such as those of the European Society for Microcirculation, the World Congress for Microcirculation, the European Society for the Study of Diabetes, the American Diabetes Association, the European Society for Cardiology, and the American Heart Association.

His research programme focuses on the elucidation of how metabolic changes in (pre)diabetes and the metabolic syndrome cause micro- and macrovascular disease. A key element of the programme is to combine epidemiology, clinical physiology and experimental approaches, in the conviction that these approaches should complement and mutually inspire each other. He is one of the principal investigators of the well-known Hoorn Study (since 1992). He also obtained national and European funding (16 M€) for, and is the initiator and Scientific Director of the Maastricht Study (started 2010), which combines very detailed phenotyping (with a focus on microcirculatory, large artery and cardiac function and structure) with an ‘omics’ approach in 7000 individuals without and 2000 with type 2 diabetes to elucidate how diabetes leads not only to classic complications but also to so-called emerging complications such as cognitive dysfunction, mood disorders, liver disease, musculoskeletal disease, pulmonary disease, sleep-disordered breathing, and infectious diseases.

Department of Internal Medicine
P. Debyelaan 25, 6229 HX Maastricht
PO Box 616, 6200 MD Maastricht
T:+31(0)43 387 70 06

  • 2018
    • de Waard, E. A. C., de Jong, J. J. A., Koster, A., Savelberg, H. H. C. M., van Geel, T. A., Houben, A. J. H. M., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Berendschot, T. T. J. M., Schouten, J. S. A. G., Geusens, P. P. M. M., & van den Bergh, J. P. W. (2018). The association between diabetes status, HbA1c, diabetes duration, microvascular disease, and bone quality of the distal radius and tibia as measured with high-resolution peripheral quantitative computed tomography: The Maastricht Study. Osteoporosis International, 29(12), 2725-2738. https://doi.org/10.1007/s00198-018-4678-3
    • van der Velde, J. H. P. M., Schaper, N. C., Stehouwer, C. D. A., van der Kallen, C. J. H., Sep, S. J. S., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., Eussen, S. J. P. M., van Dongen, M. C. J. M., Savelberg, H. H. C. M., & Koster, A. (2018). Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study. Diabetologia, 61(12), 2561-2569. https://doi.org/10.1007/s00125-018-4719-7
    • Gala, T. D. L. H., Herder, C., Rutters, F., Carstensen-Kirberg, M., Huth, C., Stehouwer, C. D. A., Nijpels, G., Schalkwijk, C., Flyvbjerg, A., Franks, P. W., Dekker, J., Meisinger, C., Koenig, W., Roden, M., Rathmann, W., Peters, A., Thorand, B., & IMI DIRECT Consortium (2018). Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study. Diabetes-metabolism Research and Reviews, 34(8), [3063]. https://doi.org/10.1002/dmrr.3063
    • Bosma, H., Qi, Y., van Boxtel, M., Kohler, S., Schaper, N., Schram, M., Stehouwer, C., & Koster, A. (2018). Disentangling the higher risks of type 2 diabetes in lower educated people.European Journal of Public Health, 28, 50-51.
    • Liesenborghs, I., De Clerck, E. E. B., Berendschot, T. T. J. M., Goezinne, F., Schram, M. T., Henry, R. M. A., Stehouwer, C. D. A., Webers, C. A. B., & Schouten, J. S. A. G. (2018). Prevalence of optical coherence tomography detected vitreomacular interface disorders: The Maastricht Study. Acta Ophthalmologica, 96(7), 729-736. https://doi.org/10.1111/aos.13671
    • Simons, P. I. H. G., Simons, N., Stehouwer, C. D. A., Schalkwijk, C. G., Schaper, N. C., & Brouwers, M. C. G. J. (2018). Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis. PLOS ONE, 13(10), [0206174]. https://doi.org/10.1371/journal.pone.0206174
    • Bijnen, M., Beelen, N., Wetzels, S., van De Gaar, J., Vroomen, M., Wijnands, E., Scheijen, J. L., van de Waarenburg, M. P. H., Gijbels, M. J., Cleutjens, J. P., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2018). RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr(-/-) mice. Scientific Reports, 8, [15256]. https://doi.org/10.1038/s41598-018-33661-y
    • Zhou, T. L., Henry, R. M. A., Stehouwer, C. D. A., van Sloten, T. T., Reesink, K. D., & Kroon, A. A. (2018). Blood Pressure Variability, Arterial Stiffness, and Arterial Remodeling: The Maastricht Study. Hypertension, 72(4), 1002-1010. https://doi.org/10.1161/HYPERTENSIONAHA.118.11325
    • CODAM study, Maastricht Study, & CODAM study (2018). Abdominal subcutaneous adipose tissue gene expression in relation to tissue-specific insulin resistance in human obesity. Diabetologia, 61, S110-S110.
    • Ozcan, B., Rutters, F., Snoek, F. J., Roosendaal, M., Sijbrands, E. J., Elders, P. J. M., Holleman, F., Pijl, H., Tack, C. J., Abbink, E. J., de Valk, H. W., Wolffenbuttel, B. H. R., Stehouwer, C. D. A., Schaper, N. C., Dekker, J. M., Schram, M. T., & Diabet Peart Parelsnoer Initiative (2018). High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort. Diabetes Care, 41(9), 1854-1861. https://doi.org/10.2337/dc17-2181
    • Stehouwer, C. D. A. (2018). Microvascular Dysfunction and Hyperglycemia: A Vicious Cycle With Widespread Consequences. Diabetes, 67(9), 1729-1741. https://doi.org/10.2337/dbi17-0044
    • Martens, R. J. H., & Stehouwer, C. D. A. (2018). A possible role of decreased human serum albumin in the endothelial dysfunction caused by albuminuria Reply. Journal of Hypertension, 36(9), 1948-1949. https://doi.org/10.1097/HJH.0000000000001832
    • Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Roodt, J. O. H., Henry, R. M. A., Reesink, K. D., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2018). Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study. Atherosclerosis, 276, 15-22. https://doi.org/10.1016/j.atherosclerosis.2018.07.003
    • de Waard, E. A. C., Sarodnik, C., Pennings, A., de Jong, J. J. A., Savelberg, H. H. C. M., van Geel, T. A., van der Kallen, C. J., Stehouwer, C. D. A., Schram, M. T., Schaper, N., Dagnelie, P. C., Geusens, P. P. M. M., Koster, A., van Rietbergen, B., & van den Bergh, J. P. W. (2018). Reliability of HR-pQCT Derived Cortical Bone Structural Parameters When Using Uncorrected Instead of Corrected Automatically Generated Endocortical Contours in a Cross-Sectional Study: The Maastricht Study. Calcified Tissue International, 103(3), 252-265. https://doi.org/10.1007/s00223-018-0416-2
    • Hanssen, N. M. J., Westerink, J., Scheijen, J. L. J. M., van der Graaf, Y., Stehouwer, C. D. A., Schalkwijk, C. G., & SMART Study Grp (2018). Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes. Diabetes Care, 41(8), 1689-1695. https://doi.org/10.2337/dc18-0159
    • Out, M., Top, W. M. C., Lehert, P., Schalkwijk, C. A., Stehouwer, C. D. A., & Kooy, A. (2018). Long-term treatment with metformin in type 2 diabetes and vitamin D levels: A post-hoc analysis of a randomized placebo-controlled trial. Diabetes Obesity & Metabolism, 20(8), 1951-1956. https://doi.org/10.1111/dom.13327
    • Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., van der Kallen, C. J. H., Koster, A., Henry, R. M. A., Stehouwer, C. D. A., Savelkoul, P. H. M., Schaper, N. C., & Schram, M. T. (2018). Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study. Diabetes Care, 41(8), 1654-1662. https://doi.org/10.2337/dc17-2144
    • Veugen, M. G. J., Henry, R. M. A., Brunner-La Rocca, H-P., Dagnelie, P. C., Schram, M. T., van Agtmaal, M. J. M., van der Kallen, C. J. H., Sep, S. J. S., van Boxtel, M. P. J., Bekers, O., Meex, S. J. R., Jansen, J. F. A., Kroon, A. A., & Stehouwer, C. D. A. (2018). Cross-sectional associations between cardiac biomarkers, cognitive performance, and structural brain changes are modified by age: The Maastricht Study. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1948-1958. https://doi.org/10.1161/ATVBAHA.118.311082
    • Rensma, S. P., van Sloten, T. T., Launer, L. J., & Stehouwer, C. D. A. (2018). Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 90, 164-173. https://doi.org/10.1016/j.neubiorev.2018.04.003
    • Sedaghat, S., van Sloten, T. T., Laurent, S., London, G. M., Pannier, B., Kavousi, M., Mattace-Raso, F., Franco, O. H., Boutouyrie, P., Ikram, M. A., & Stehouwer, C. D. A. (2018). Common Carotid Artery Diameter and Risk of Cardiovascular Events and Mortality: Pooled Analyses of Four Cohort Studies. Hypertension, 72(1), 85-92. https://doi.org/10.1161/HYPERTENSIONAHA.118.11253
    • Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2018). Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice. Gut, 67(7), 1317-1327. https://doi.org/10.1136/gutjnl-2016-313654
    • Out, M., Becker, M. L., van Schaik, R. H., Lehert, P., Stehouwer, C. D., & Kooy, A. (2018). A gene variant near ATM affects the response to metformin and metformin plasma levels: a post hoc analysis of an RCT. Pharmacogenomics, 19(8), 715-726. https://doi.org/10.2217/pgs-2018-0010
    • Nielen, J. T. H., Emans, P. J., van den Bemt, B., Dagnelie, P. C., Schram, M. T., Stehouwer, C. D. A., Schaper, N. C., Denissen, K. F. M., de Vries, F., & Boonen, A. (2018). Association of type 2 diabetes mellitus with self-reported knee pain and clinical knee osteoarthritis: The Maastricht Study. Diabetes & Metabolism, 44(3), 296-299. https://doi.org/10.1016/j.diabet.2018.01.013
    • Scheijen, J. L. J. M., Hanssen, N. M. J., van Greevenbroek, M. M., van der Kallen, C. J., Feskens, E. J. M., Stehouwer, C. D. A., & Schalkwijk, C. G. (2018). Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study. Clinical Nutrition, 37(3), 919-925. https://doi.org/10.1016/j.clnu.2017.03.019
    • van Bussel, B. C. T., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Feskens, E. J. M., & Stehouwer, C. D. A. (2018). Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study. European Journal of Nutrition, 57(4), 1409-1419. https://doi.org/10.1007/s00394-017-1420-4
    • Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Classical Pathway of Complement Activation: Longitudinal Associations of C1q and C1-INH With Cardiovascular Outcomes: The CODAM Study (Cohort on Diabetes and Atherosclerosis Maastricht)Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1242-1244. https://doi.org/10.1161/ATVBAHA.118.310806
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Longitudinal associations of the alternative and terminal pathways of complement activation with adiposity: The CODAM study. Obesity Research & Clinical Practice, 12(3), 286-292. https://doi.org/10.1016/j.orcp.2017.11.002
    • Martens, R. J. H., Houben, A. J. H. M., Kooman, J. P., Berendschot, T. T. J. M., Dagnelie, P. C., van der Kallen, C. J. H., Kroon, A. A., Leunissen, K. M. L., van der Sande, F. M., Schaper, N. C., Schouten, J. S. A. G., Schram, M. T., Sep, S. J. S., Sörensen, B. M., Henry, R. M. A., & Stehouwer, C. D. A. (2018). Microvascular endothelial dysfunction is associated with albuminuria: the Maastricht Study. Journal of Hypertension, 36(5), 1178-1187. https://doi.org/10.1097/HJH.0000000000001674
    • Lorenz, M. W., Gao, L., Ziegelbauer, K., Norata, G. D., Empana, J. P., Schmidtmann, I., Lin, H-J., McLachlan, S., Bokemark, L., Ronkainen, K., Amato, M., Schminke, U., Srinivasan, S. R., Lind, L., Okazaki, S., Stehouwer, C. D. A., Willeit, P., Polak, J. F., Steinmetz, H., ... PROG-IMT Study Grp (2018). Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk: Results from the PROGIMT collaboration . PLOS ONE, 13(4), [e0191172]. https://doi.org/10.1371/journal.pone.0191172
    • Martens, R. J. H., van der Berg, J. D., Stehouwer, C. D. A., Henry, R. M. A., Bosma, H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Schram, M. T., Sep, S. J. S., van der Kellen, C. J. H., Schaper, N. C., Savelberg, H. H. C. M., van der Sande, F. M., Kroon, A. A., Kooman, J. P., & Koster, A. (2018). Amount and pattern of physical activity and sedentary behavior are associated with kidney function and kidney damage: The Maastricht Study. PLOS ONE, 13(4), [0195306]. https://doi.org/10.1371/journal.pone.0195306
    • Rutters, F., Nijpels, G., Elders, P., Stehouwer, C. D. A., van der Heijden, A. A., Groeneveld, L., 'T Hart, L. M., Dekker, J. M., & Beulens, J. W. J. (2018). Cohort Profile: The Hoorn Studies. International Journal of Epidemiology, 47(2), 396–396j. https://doi.org/10.1093/ije/dyx227
    • Scheepers, L. E. J. M., van Onna, M., Stehouwer, C. D. A., Singh, J. A., Arts, I. C. W., & Boonen, A. (2018). Medication adherence among patients with gout: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism, 47(5), 689-702. https://doi.org/10.1016/j.semarthrit.2017.09.007
    • Pulakka, A., Stenholm, S., Bosma, H., Schaper, N. C., Savelberg, H. H. C. M., Stehouwer, C. D. A., van der Kallen, C. J. H., Dagnelie, P. C., Sep, S. J. S., & Koster, A. (2018). Association Between Employment Status and Objectively Measured Physical Activity and Sedentary BehaviorThe Maastricht Study. Journal of Occupational and Environmental Medicine, 60(4), 309-315. https://doi.org/10.1097/JOM.0000000000001254
    • van Dalem, J., Brouwers, M. C. G. J., Stehouwer, C. D. A., Krings, A., Klungel, O. H., Driessen, J. H. M., de Vries, F., & Burden, A. M. (2018). Risk of a first-ever acute myocardial infarction and all-cause mortality with sulphonylurea treatment: A population-based cohort study. Diabetes Obesity & Metabolism, 20(4), 1056-1060. https://doi.org/10.1111/dom.13168
    • Verboven, K., Wouters, K., Gaens, K., Hansen, D., Bijnen, M., Wetzels, S., Stehouwer, C. D., Goossens, G. H., Schalkwijk, C. G., Blaak, E. E., & Jocken, J. W. (2018). Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans. Scientific Reports, 8, [4677]. https://doi.org/10.1038/s41598-018-22962-x
    • Onete, V., Henry, R. M., Sep, S. J. S., Koster, A., van der Kallen, C. J., Dagnelie, P. C., Schaper, N., Kohler, S., Reesink, K., Stehouwer, C. D. A., & Schram, M. T. (2018). Arterial stiffness is associated with depression in middle-aged men - the Maastricht Study. Journal of Psychiatry & Neuroscience, 43(2), 111-119. https://doi.org/10.1503/jpn.160246
    • Peeters, S. A., Engelen, L., Buijs, J., Theilade, S., Rossing, P., Schalkwijk, C. G., & Stehouwer, C. D. A. (2018). Associations between advanced glycation endproducts and matrix metalloproteinases and its inhibitor in individuals with type 1 diabetes. Journal of Diabetes and Its Complications, 32(3), 325-329. https://doi.org/10.1016/j.jdiacomp.2017.12.011
    • Top, W., Stehouwer, C., Lehert, P., & Kooy, A. (2018). Metformin and -cell function in insulin-treated patients with type 2 diabetes: A randomized placebo-controlled 4.3-year trial. Diabetes Obesity & Metabolism, 20(3), 730-733. https://doi.org/10.1111/dom.13123
    • Stehouwer, C. D. A. (2018). The metabolic-microvascular dysregulation syndrome. Artery Research, 21, 78-83. https://doi.org/10.1016/j.artres.2017.12.005
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Goezinne, F., Dagnelie, P. C., Schaper, N. C., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2018). Macular thinning in prediabetes or type 2 diabetes without diabetic retinopathy: the Maastricht Study. Acta Ophthalmologica, 96(2), 174-182. https://doi.org/10.1111/aos.13570
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Goezinne, F., Liesenborghs, I., Dagnelie, P. C., Schaper, N. C., Kroon, A. A., Henry, R. M. A., Reesink, K. D., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2018). Vascular risk factors for optical coherence tomography-detected cystoid macular edema: the Maastricht study. Acta Ophthalmologica, 96, 25-25.
    • Out, M., Kooy, A., Lehert, P., Schalkwijk, C. A., & Stehouwer, C. D. A. (2018). Long-term treatment with metformin in type 2 diabetes and methylmalonic acid: Post hoc analysis of a randomized controlled 4.3 year trial. Journal of Diabetes and Its Complications, 32(2), 171-178. https://doi.org/10.1016/j.jdiacomp.2017.11.001
    • Schutten, M. T. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Schalkwijk, C. G., Joris, P. J., Plat, J., Mensink, R. P., de Leeuw, P. W., & Stehouwer, C. D. A. (2018). Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men. Journal of Clinical Endocrinology & Metabolism, 103(2), 759-767. https://doi.org/10.1210/jc.2017-01541
    • Zhou, T. L., Reesink, K., Schram, M., Koster, A., Schaper, N., Dagnelie, P., van der Kallen, C., Sep, S., Stehouwer, C., & Henry, R. (2018). Blood pressure variability in individuals with and without (pre)diabetes: the Maastricht Study. Journal of Hypertension, 36(2), 259-267. https://doi.org/10.1097/HJH.0000000000001543
    • Yousefi, S., Abbassi-Daloii, T., Kraaijenbrink, T., Vermaat, M., Mei, H., van't Hof, P., van Iterson, M., Zhernakova, D. V., Claringbould, A., Franke, L., 't Hart, L. M., Slieker, R. C., van der Heijden, A., de Knijff, P., 't Hoen, P. A. C., BIOS Consortium, Jansen, R., van Meurs, J., Heijmans, B. T., ... Franke, L. (2018). A SNP panel for identification of DNA and RNA specimens. BMC Genomics, 19(90), [90]. https://doi.org/10.1186/s12864-018-4482-7
    • Martens, R. J. H., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Kroon, A. A., Leunissen, K. M. L., van der Sande, F. M., Schaper, N. C., Sep, S. J. S., Kohler, S., Schram, M. T., & Henry, R. M. A. (2018). Albuminuria is associated with a higher prevalence of depression in a population-based cohort study: the Maastricht Study. Nephrology Dialysis Transplantation, 33(1), 128-138. https://doi.org/10.1093/ndt/gfw377
    • Geijselaers, S. L. C., Aalten, P., Ramakers, I. H. G. B., De Deyn, P. P., Heijboer, A. C., Koek, H. L., OldeRikkert, M. G. M., Papma, J. M., Reesink, F. E., Smits, L. L., Stehouwer, C. D. A., Teunissen, C. E., Verhey, F. R. J., van der Flier, W. M., Biessels, G. J., & Inst Neurodegenerative Dis Study G (2018). Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease. Journal of Alzheimer's Disease, 61(1), 309-320. https://doi.org/10.3233/JAD-170522
    • Ferreira, I., Hovind, P., Schalkwijk, C. G., Parving, H-H., Stehouwer, C. D. A., & Rossing, P. (2018). Biomarkers of inflammation and endothelial dysfunction as predictors of pulse pressure and incident hypertension in type 1 diabetes: a 20 year life-course study in an inception cohort. Diabetologia, 61(1), 231-241. https://doi.org/10.1007/s00125-017-4470-5
    • Wanders, A. J., Alssema, M., De Hoon, S. E. M., Feskens, E. J. M., van Woudenbergh, G. J., van der Kallen, C. J., Zock, P. L., Refsum, H., Drevon, C. A., Elshorbagy, A., Schalkwijk, C. G., Stehouwer, C. D. A., Dekker, J. M., & van Greevenbroek, M. M. J. (2018). Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies. Annals of Nutrition and Metabolism, 72(2), 117-125. https://doi.org/10.1159/000486244
    • Out, M., Miedema, I., Jager-Wittenaar, H., van der Schans, C., Krijnen, W., Lehert, P., Stehouwer, C., & Kooy, A. (2018). Metformin-associated prevention of weight gain in insulin-treated type 2 diabetic patients cannot be explained by decreased energy intake: A post hoc analysis of a randomized placebo-controlled 4.3-year trial. Diabetes Obesity & Metabolism, 20(1), 219-223. https://doi.org/10.1111/dom.13054