Marleen van Greevenbroek

Associate professor

Dr Marleen van Greevenbroek is Medical Biologist (University of Utrecht, 1992) and Epidemiologist (Maastricht University, 2012). She received her PhD degree in 1997 at the University of Utrecht, on a thesis concerning the effects of fatty acids on the production of intestinal triglyceride-rich lipoproteins. In September 1997, she was appointed at the University of Maastricht (Dept. of Internal Medicine), where she was involved in studies on the metabolic and genetic aspects of obesity and cardiometabolic diseases.

Her main area of research is the identification of early events in the development of insulin resistance, type 2 diabetes, and cardiovascular disease. In recent years, her research activities specifically focused on the role of the complement system herein. This research encompasses both cohort studies and experimental work.

 

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2024
    • Olsen, T., Stolt, E., Øvrebø, B., Elshorbagy, A., Tore, E. C., Lee-Ødegård, S., Troensegaard, H., Johannessen, H., Doeland, B., Vo, A. A. D., Dahl, A. F., Svendsen, K., Thoresen, M., Refsum, H., Rising, R., Barvíková, K., van Greevenbroek, M., Kožich, V., Retterstøl, K., & Vinknes, K. J. (2024). Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial. Journal of Translational Medicine, 22(1), Article 40. https://doi.org/10.1186/s12967-023-04833-w
    • den Brok, E. J., Svensson, C. H., Panagiotou, M., van Greevenbroek, M. M. J., Mertens, P. R., Vazeou, A., Mitrakou, A., Makrilakis, K., Franssen, G. H. L. M., van Kuijk, S., Proennecke, S., Mougiakakou, S., Pedersen-Bjergaard, U., de Galan, B. E., & Melissa Consortium (2024). The effect of bolus advisors on glycaemic parameters in adults with diabetes on intensive insulin therapy: A systematic review with meta-analysis. Diabetes Obesity & Metabolism, 26(5), 1950-1961. Advance online publication. https://doi.org/10.1111/dom.15521
    • van Gennip, A. C. E., Gupta, M. D., Houben, A. J. H. M., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Koster, A., Wesselius, A., Eussen, S. J. P. M., Schalkwijk, C. G., de Galan, B. E., Köhler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2024). Retinal microvascular function and incidence and trajectories of clinically relevant depressive symptoms: the Maastricht Study. Psychological Medicine, 1-10. Advance online publication. https://doi.org/10.1017/S0033291724000618
    • Beran, M., van Gennip, A. C. E., Stehouwer, C. D. A., Jansen, J. F. A., Gupta, M. D., Houben, A. J. H. M., Berendschot, T. T. J. M., Webers, C. A. B., Wesselius, A., Schalkwijk, C. G., Backes, W. H., de Jong, J. J. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Köhler, S., Vonk, J. M. J., Geerlings, M. I., Schram, M. T., & van Sloten, T. T. (2024). Microvascular Dysfunction and Whole-Brain White Matter Connectivity: The Maastricht Study. Journal of the American Heart Association, 13(3), Article e9112. https://doi.org/10.1161/JAHA.123.031573
    • van der Heide, F. C. T., Steens, I. L. M., Limmen, B., Mokhtar, S., van Boxtel, M. P. J., Schram, M. T., Köhler, S., Kroon, A. A., van der Kallen, C. J. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., Koster, A., van Sloten, T. T., Jansen, J. F. A., Backes, W. H., & Stehouwer, C. D. A. (2024). Thinner inner retinal layers are associated with lower cognitive performance, lower brain volume, and altered white matter network structure-The Maastricht Study. Alzheimer's & Dementia, 20(1), 316-329. https://doi.org/10.1002/alz.13442
    • Meisters, R., Albers, J., Sezer, B., de Galan, B. E., Eussen, S. J. P. M., Stehouwer, C. D. A., Schram, M. T., van Greevenbroek, M. M. J., Wesselius, A., Koster, A., & Bosma, H. (2024). Socioeconomic inequalities in health-related functioning among people with type 2 Diabetes: longitudinal analyses in the Maastricht Study. BMC Public Health, 24(1), Article 73. https://doi.org/10.1186/s12889-023-17553-z
  • 2023
    • Ren, Z., Bosma, H., Wesselius, A., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., Koster, A., van Greevenbroek, M. M. J., Dagnelie, P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Traditional lifestyle factors partly mediate the association of socioeconomic position with intrahepatic lipid content: The Maastricht study. JHEP Reports, 5(11), Article 100855. https://doi.org/10.1016/j.jhepr.2023.100855
    • Feng, L., Ye, Z., Mo, C., Wang, J., Liu, S., Gao, S., Ke, H., Canida, T. A., Pan, Y., Greevenbroek, M. M. J. V., Houben, A. J. H. M., Wang, K., Hatch, K. S., Ma, Y., Lei, D. K. Y., Chen, C., Mitchell, B. D., Hong, L. E., Kochunov, P., ... Ma, T. (2023). Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK Biobank. Journal of Hypertension, 41(11), 1811-1820. https://doi.org/10.1097/HJH.0000000000003553
    • Mokhtar, S. B. A., van der Heide, F. C. T., Oyaert, K. A. M., van der Kallen, C. J. H., Berendschot, T. T. J. M., Scarpa, F., Colonna, A., de Galan, B. E., van Greevenbroek, M. M. J., Dagnelie, P. C., Schalkwijk, C. G., Nuijts, R. M. M. A., Schaper, N. C., Kroon, A. A., Schram, M. T., Webers, C. A. B., & Stehouwer, C. D. A. (2023). (Pre)diabetes and a higher level of glycaemic measures are continuously associated with corneal neurodegeneration assessed by corneal confocal microscopy: the Maastricht Study. Diabetologia, 66(11), 2030-2041. https://doi.org/10.1007/s00125-023-05986-5
    • Bellos, I., Marinaki, S., Lagiou, P., Boletis, I. N., Stehouwer, C. D. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., de Galan, B. E., Savelberg, H. H. C. M., Koster, A., Wesselius, A., & Benetou, V. (2023). Association of physical activity with endothelial dysfunction among adults with and without chronic kidney disease: The Maastricht Study. Atherosclerosis, 383(1), Article 117330. https://doi.org/10.1016/j.atherosclerosis.2023.117330
    • Zhang, Y., Guloksuz, S., Stehouwer, C., Greevenbroek, M., Kohler, S., Eussen, S., Bosma, H., Boxtel, M., Schram, M., Linden, D., Rutten, B., & Blokland, G. (2023). The Additive Value Of Brain Lifestyle In The Explanatory Ability Of Polygenic Risk Profiles On Cognitive Performance In Aging Individuals. European Neuropsychopharmacology, 75, S169-S170. https://doi.org/10.1016/j.euroneuro.2023.08.303
    • Albers, J. D., Meertens, R. M., Savelberg, H. H. C. M., Köhler, S., Wesselius, A., Schram, M. T., Stehouwer, C. D. A., de Galan, B. E., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Eussen, S. J. P. M., Bosma, H., Schaper, N. C., & Koster, A. (2023). Both short and long sleep durations are associated with type 2 diabetes, independent from traditional lifestyle risk factors-The Maastricht Study. Sleep Health, 9(5), 733-741. https://doi.org/10.1016/j.sleh.2023.06.009
    • van Dongen, J., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Neale, M. C., BIOS Consortium, van Greevenbroek, M., Stehouwer, C., van der Kallen, C., & Schalkwijk, C. (2023). Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs. Elife, 12, Article e83286. https://doi.org/10.7554/eLife.83286
    • Erdős, B., Van sloun, B., Goossens, G. H., O’donovan, S. D., De galan, B. E., Van greevenbroek, M. M. J., Stehouwer, C. D. A., Schram, M. T., Blaak, E. E., Adriaens, M. E., Van riel, N. A. W., & Arts, I. C. W. (2023). Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study. PLOS ONE, 18(7), Article e0285820. https://doi.org/10.1371/journal.pone.0285820
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2023). Habitual Intake of Dietary Dicarbonyls is Associated with Greater Insulin Sensitivity and Lower Prevalence of Type 2 Diabetes: The Maastricht Study. American Journal of Clinical Nutrition, 118(1), 151-161. https://doi.org/10.1016/j.ajcnut.2023.04.011
    • Jin, S., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2023). Plasma factor D is cross-sectionally associated with low-grade inflammation, endothelial dysfunction and cardiovascular disease: The Maastricht study. Atherosclerosis, 377(1), 60-67. https://doi.org/10.1016/j.atherosclerosis.2023.06.079
    • Tore, E. C., Eussen, S. J. P. M., Bastani, N. E., Dagnelie, P. C., Elshorbagy, A. K., Grootswagers, P., Kozich, V., Olsen, T., Refsum, H., Retterstol, K., Stehouwer, C. D. A., Stolt, E. T. K., Vinknes, K. J., & van Greevenbroek, M. M. J. (2023). The Associations of Habitual Intake of Sulfur Amino Acids, Proteins and Diet Quality with Plasma Sulfur Amino Acid Concentrations: The Maastricht Study. Journal of Nutrition, 153(7), 2027-2040. https://doi.org/10.1016/j.tjnut.2023.05.008
    • Wauben, B., van der Poel, M. W. M., Greevenbroek, M. M. J., van Yperen, N. C., Schram, M. T., van Boxtel, M. P. J., Sastry, M., Simons, S. O., Stehouwer, C. D. A., Dagnelie, P. C., Wesselius, A., Schouten, H. C., & Köhler, S. (2023). Cognitive Functioning in Survivors of Hematopoietic Stem Cell Transplantation Compared With a Matched General Population Sample—The Maastricht Observational Study of Late Effects After Stem Cell trAnsplantation Study. Transplantation and Cellular Therapy, 29(7), 468.e1-468.e8. https://doi.org/10.1016/j.jtct.2023.03.026
    • de Ritter, R., Sep, S. J. S., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Koster, A., Eussen, S. J. P. M., Dagnelie, P. C., van Boxtel, M., Schram, M. T., Kohler, S., Martens, J. A. J., Snobl, L., Vos, R. C., Stehouwer, C. D. A., & Peters, S. A. E. (2023). Sex comparisons in the association of prediabetes and type 2 diabetes with cognitive function, depression, and quality of life: The Maastricht study. Diabetic Medicine, 40(7). https://doi.org/10.1111/dme.15115
    • Chan, J. A., Koster, A., Eussen, S. J. P. M., Pinho, M. G. M., Lakerveld, J., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J., van Greevenbroek, M. M. J., Wesselius, A., & Bosma, H. (2023). The association between the food environment and adherence to healthy diet quality: the Maastricht Study. Public Health Nutrition, 26(9), 1775-1783. Article PII S1368980023001180. https://doi.org/10.1017/S1368980023001180
    • Rinaldi, E., van der Heide, F. C. T., Bonora, E., Trombetta, M., Zusi, C., Kroon, A. A., Schram, M. T., van der Kallen, C. J. H., Wesselius, A., Bonadonna, R., Mari, A., Schalkwijk, C. G., van Greevenbroek, M. M. J., & Stehouwer, C. D. A. (2023). Lower heart rate variability, an index of worse autonomic function, is associated with worse beta cell response to a glycemic load in vivo-The Maastricht Study. Cardiovascular Diabetology, 22(1), Article 105. https://doi.org/10.1186/s12933-023-01837-0
    • Trouwborst, I., Wouters, K., Jocken, J. W., Jardon, K. M., Gijbels, A., Dagnelie, P. C., van Greevenbroek, M. M. J., van der Kallen, C. J., Stehouwer, C. D. A., Schalkwijk, C. G., Richard, N., Bendik, I., Afman, L. A., Blaak, E. E., & Goossens, G. H. (2023). Circulating and adipose tissue immune cells in tissue-specific insulin resistance in humans with overweight and obesity. Obesity, 31(5), 1326-1337. https://doi.org/10.1002/oby.23714
    • de Ritter, R., Sep, S. J. S., van Greevenbroek, M. M. J., Kusters, Y. H. A. M., Vos, R. C., Bots, M. L., Kooi, M. E., Dagnelie, P. C., Eussen, S. J. P. M., Schram, M. T., Koster, A., Brouwers, M. C. G., van der Sangen, N. M. R., Peters, S. A. E., van der Kallen, C. J. H., & Stehouwer, C. D. A. (2023). Sex differences in body composition in people with prediabetes and type 2 diabetes as compared with people with normal glucose metabolism: the Maastricht Study. Diabetologia, 66(5), 861-872. https://doi.org/10.1007/s00125-023-05880-0
    • Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schram, M. T., van Greevenbroek, M. M. J., Wesselius, A., Kooman, J. P., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2023). Accelerometer-derived physical activity and sedentary time and cardiac biomarkers: The Maastricht Study. Frontiers in Cardiovascular Medicine, 10(1), Article 1081713. https://doi.org/10.3389/fcvm.2023.1081713
    • Buziau, A. M., Blokland, G. A. M., Schalkwijk, C. G., Scheijen, J. L. J. M., Simons, P. I. H. G., Eussen, S. J. P. M., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Comment on Lee et al. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies. Diabetes Care 2022;45. Diabetes Care, 46(4), E97-E98. https://doi.org/10.2337/dc22-1930
    • van der Heide, F. C. T., Eussen, S. J. P. M., Houben, A. J. H. M., Henry, R. M. A., Kroon, A. A., van der Kallen, C. J. H., Dagnelie, P. C., van Dongen, M. C. J. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Koster, A., Jansen, J. F. A., Backes, W. H., Beulens, J. W. J., & Stehouwer, C. D. A. (2023). Alcohol consumption and microvascular dysfunction: a J-shaped association: The Maastricht Study. Cardiovascular Diabetology, 22(1), Article 67. https://doi.org/10.1186/s12933-023-01783-x
    • Tore, E. C., Elshorbagy, A. K., Bakers, F. C. H., Brouwers, M. C. G. J., Dagnelie, P. C., Eussen, S. J. P. M., Jansen, J. F. A., Kooi, M. E., Kusters, Y. H. A. M., Meex, S. J. R., Olsen, T., Refsum, H., Retterstøl, K., Schalkwijk, C. G., Stehouwer, C. D. A., Vinknes, K. J., & van Greevenbroek, M. M. J. (2023). Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study. European Journal of Nutrition, 62(2), 891-904. https://doi.org/10.1007/s00394-022-03041-4
    • Buziau, A. M., Law, P. J., Blokland, G., Schalkwijk, C., Scheijen, J., Simons, P., van der Kallen, C., Eussen, S., Dagnelie, P. C., van Greevenbroek, M., Houlston, R. S., Wesselius, A., Went, M., Stehouwer, C., & Brouwers, M. C. (2023). Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study. Gut, 72(3), 604-606. https://doi.org/10.1136/gutjnl-2021-326299
    • van Yperen, N. C., Wauben, B., van der Poel, M. W., Köhler, S., van Greevenbroek, M. M., & Schouten, H. C. (2023). Selection bias in follow-up studies of stem cell transplantation survivors: an experience within the Maastricht Observational study of late effects after Stem cell trAnsplantation (MOSA). Annals of Hematology, 102(3), 641-649. https://doi.org/10.1007/s00277-022-05070-9
    • Dekkers, K. F., Slieker, R. C., Ioan-Facsinay, A., van Iterson, M., Ikram, M. A., van Greevenbroek, M. M. J., Veldink, J. H., Franke, L., Boomsma, D. I., Slagboom, P. E., Jukema, J. W., Heijmans, B. T., & BIOS Consortium (2023). Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response. Nature Communications, 14(1), Article 544. https://doi.org/10.1038/s41467-022-35663-x
    • Zhou, T. L., Reulen, J. P. H., Van Der Staaij, H., Stehouwer, C. D. A., Van Greevenbroek, M., Henry, R. M. A., & Kroon, A. A. (2023). Cardiovagal baroreflex sensitivity, blood pressure and blood pressure variability - the Maastricht study. Journal of Hypertension, 41(2), 254-261. https://doi.org/10.1097/HJH.0000000000003323
    • Zhou, T. L., Schutten, M. T. J., Kroon, A. A., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., van Greevenbroek, M. M. J., de Leeuw, P. W., & Stehouwer, C. D. A. (2023). Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. Journal of the American Heart Association, 12(1), Article e026578. https://doi.org/10.1161/JAHA.122.026578
    • Simons, P. I. H. G., Valkenburg, O., van de Waarenburg, M. P. H., van Greevenbroek, M. M. J., Kooi, M. E., Jansen, J. F. A., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study. Diabetologia, 66(1), 213-222. https://doi.org/10.1007/s00125-022-05790-7
    • van der Heide, F. C. T., Mokhtar, S., Khanna, A., Said, M., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Savelberg, H. H. C. M., Schaper, N. C., Webers, C. A. B., & Stehouwer, C. D. A. (2023). Retinal Functional and Structural Neural Indices: Potential Biomarkers for the Monitoring of Cerebral Neurodegeneration: The Maastricht Study. Journal of Alzheimer's Disease, 93(4), 1471-1483. https://doi.org/10.3233/JAD-230104
  • 2022
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Houben, A. J. H. M., Webers, C. A. B., Schram, M. T., Berendschot, T. T. J. M., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Habitual intake of dietary methylglyoxal is associated with less low-grade inflammation: the Maastricht Study. American Journal of Clinical Nutrition, 116(6), 1715-1728. https://doi.org/10.1093/ajcn/nqac195
    • Gianfredi, V., Schaper, N. C., Odone, A., Signorelli, C., Amerio, A., Eussen, S. J. P. M., Köhler, S., Savelberg, H. H. C. M., Stehouwer, C. D. A., Dagnelie, P. C., Henry, R. M. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schram, M. T., & Koster, A. (2022). Daily patterns of physical activity, sedentary behavior, and prevalent and incident depression-The Maastricht Study. Scandinavian Journal of Medicine & Science in Sports, 32(12), 1768-1780. https://doi.org/10.1111/sms.14235
    • Yu, E. Y.-W., Ren, Z., Mehrkanoon, S., Stehouwer, C. D. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Zeegers, M. P., & Wesselius, A. (2022). Plasma metabolomic profiling of dietary patterns associated with glucose metabolism status: The Maastricht Study. BMC Medicine, 20(1), 450. https://doi.org/10.1186/s12916-022-02653-1
    • Jin, S., Reesink, K. D., Kroon, A. A., de Galan, B., van der Kallen, C. J. H., Wesselius, A., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study. Journal of Hypertension, 40(11), 2161-2170. https://doi.org/10.1097/HJH.0000000000003237
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Koster, A., Dagnelie, P. C., van Greevenbroek, M. M. J., Stehouwer, C. D. A., Verhey, F. R. J., & Köhler, S. (2022). The relation of depression with structural brain abnormalities and cognitive functioning: the Maastricht study. Psychological Medicine, 52(15), 3521–3530. https://doi.org/10.1017/S0033291721000222
    • van der Heide, F. C. T., Foreman, Y. D., Franken, I. W. M., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Schaper, N. C., Brouwers, M. C. G. J., & Stehouwer, C. D. A. (2022). (Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study. Scientific Reports, 12(1), Article 17750. https://doi.org/10.1038/s41598-022-22748-2
    • Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043. https://doi.org/10.1016/j.dld.2022.01.130
    • Wauben, B., van Yperen, N. C., van der Poel, M. W., Köhler, S., van Greevenbroek, M. M., & Schouten, H. C. (2022). Long-term effects after stem cell transplantation identified: design of the MOSA study. Journal of Clinical Epidemiology, 148, 10-16. https://doi.org/10.1016/j.jclinepi.2022.03.012
    • Jin, S., Kusters, Y. H. A. M., Houben, A. J. H. M., Plat, J., Joris, P. J., Mensink, R. P., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). A randomized diet-induced weight-loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction. Obesity, 30(7), 1401-1410. https://doi.org/10.1002/oby.23467
    • Buziau, A. M., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., van Dongen, M. C. J. M., Schaper, N. C., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Bekers, O., Meex, S. J. R., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes Care, 45(5), 1116-1123. https://doi.org/10.2337/dc21-2123
    • Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schaper, N. C., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2022). Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation-relevance for (pre)diabetes: The Maastricht Study. Diabetologia, 65(5), 777-789. https://doi.org/10.1007/s00125-022-05651-3
    • Hop, P. J., Zwamborn, R. A. J., Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H. J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al Khleifat, A., Iacoangeli, A., Ticozzi, N., Ratti, A., Cooper-Knock, J., ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14(633), Article eabj0264. https://doi.org/10.1126/scitranslmed.abj0264
    • Linkens, A. M. A., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M., Henry, R. M. A., de Galan, B., Stehouwer, C. D. A., Eussen, S. J. M. P., & Schalkwijk, C. G. (2022). Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study. American Journal of Clinical Nutrition, 115(2), 444-455. https://doi.org/10.1093/ajcn/nqab302
    • Jonkman, T. H., Dekkers, K. F., Slieker, R. C., Grant, C. D., Ikram, M. A., van Greevenbroek, M. M. J., Franke, L., Veldink, J. H., Boomsma, D. I., Slagboom, P. E., B. I. O. S. Consortium, & Heijmans, B. T. (2022). Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression. Genome Biology, 23(1), Article 24. https://doi.org/10.1186/s13059-021-02585-8
    • Maasen, K., Eussen, S. J. P. M., Scheijen, J. L. J. M., van der Kallen, C. J. H., Dagnelie, P. C., Opperhuizen, A., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study. American Journal of Clinical Nutrition, 115(1), 34-44. https://doi.org/10.1093/ajcn/nqab329
  • 2021
    • Kalafati, M., Kutmon, M., Evelo, C. T., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Blaak, E. E., van Greevenbroek, M. M. J., Adriaens, M., & BIOS Consortium (2021). An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals-the CODAM study. Genes and nutrition, 16(1), Article 22. https://doi.org/10.1186/s12263-021-00702-7