Menu

Latest news & events

Professorship Julie Staals

Professorship Julie Staals

22 April 2024

Dr Julie Staals (Dept. of Neurology) has been appointed as professor 'Neurovascular disease' as of 1 April 2024.

Read more
ERC Advanced Grant awarded to Prof. Andy Baker

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Prof. Andy Baker (Dept of Pathology) has been awarded a European Research Council (ERC) Advanced Grant of €2,5M for his research project PolymiRize: Poly-miRNA targeting to prevent and reverse complex tissue remodelling after acute cardiovascular events'.

Read more
More newsMore events
Carim Maastricht
Carim Maastricht

Philippe Vangrieken

Post doc

Dr Philippe Vangrieken is a European Registered Toxicologist with a specialized focus on bioactive compound toxicity and vascular biology. He has studied Biomedical Sciences at Maastricht University. In 2016, he started his PhD research at the Department of Pharmacology & Toxicology and Gynecology at Maastricht UMC+. His PhD project titled 'Vascular complications in preeclampsia' was granted by the School of Nutrition and Translational Research in Metabolism (NUTRIM). Throughout his PhD, his research was centered on unraveling the intricate interplay of preeclampsia and its associated stressors, namely hypoxia and oxidative stress, within the placenta, and their impact on the development of vascular complications.

In 2020, he started a postdoctoral position at the laboratory of Prof. Casper Schalkwijk within the Department of Internal Medicine. Their lab has risen as a global leader in glycation research, equipped with state-of-the-art facilities dedicated to this domain. In 2021, he received a 3-year personal Junior Fellowship from the Dutch Diabetes Foundation where he studied the involvement of methylglyoxal and non-enzymatic glycation in the development of vascular complications in diabetes. His project was acknowledged by the Nederlandse Vereniging voor Diabetes Onderzoek (NVDO) with the Terpstra Award in 2022 and was also selected for additional funding from the Belgian Foundation Frans Janssen in 2023. His research bridges the gap between highly technical measurements, animal research, and cohort studies.

Philippe vangrieken min

Department of Internal Medicine
Universiteitssingel 60, 6229 ER Maastricht
P.O. Box 616, 6200 MD Maastricht
Room number: H5.334b
T: +31(0)43 388 10 88

  • 2024
    • Mircheva, A., Vangrieken, P., Al-Nasiry, S., van Schooten, F.-J., Godschalk, R. W. L., & Langie, S. A. S. (2024). Optimizing the Comet Assay-Based In Vitro DNA Repair Assay for Placental Tissue: A Pilot Study with Pre-Eclamptic Patients. International Journal of Molecular Sciences, 25(1), Article 187. https://doi.org/10.3390/ijms25010187
  • 2023
    • Bednarska, K., Fecka, I., Scheijen, J. L. J. M., Ahles, S., Vangrieken, P., & Schalkwijk, C. G. (2023). A Citrus and Pomegranate Complex Reduces Methylglyoxal in Healthy Elderly Subjects: Secondary Analysis of a Double-Blind Randomized Cross-Over Clinical Trial. International Journal of Molecular Sciences, 24(17), Article 13168. https://doi.org/10.3390/ijms241713168
  • 2021
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Placental Mitochondrial Abnormalities in Preeclampsia. Reproductive Sciences, 28(8), 2186-2199. https://doi.org/10.1007/s43032-021-00464-y
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Kaminski, I., Geomini, I., Lemmens, T., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLOS ONE, 16(1), Article 0245155. https://doi.org/10.1371/journal.pone.0245155
  • 2020
    • Vangrieken, P., Remels, A. H., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J., & Schiffers, P. M. H. (2020). Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity. Hypertension Research, 43(12), 1361-1374. https://doi.org/10.1038/s41440-020-0528-8
    • Vangrieken, P., Vanterpool, S. F., van Schooten, F. J., Al-Nasiry, S., Andriessen, P., Degreef, E., Alfer, J., Kramer, B. W., & von Rango, U. (2020). Histological villous maturation in placentas of complicated pregnancies. Histology and Histopathology, 35(8), 849-862. https://doi.org/10.14670/HH-18-205
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.
  • 2018
    • Vangrieken, P., Al-Nasiry, S., Janssen, G. M. J., Weseler, A. R., Spaanderman, M. E., Bast, A., & Schiffers, P. M. H. (2018). The direct and sustained consequences of severe placental hypoxia on vascular contractility. PLOS ONE, 13(8), Article e0202648. https://doi.org/10.1371/journal.pone.0202648
    • Zhang, M., Schiffers, P., Janssen, G., Vrolijk, M., Vangrieken, P., & Haenen, G. R. M. M. (2018). The cardiovascular side effects of Ma Huang due to its use in isolation in the Western world. European Journal of Integrative Medicine, 18, 18-22. https://doi.org/10.1016/j.eujim.2018.01.007
  • 2017
    • Sthijns, M. M. J. P. E., Schiffers, P. M., Janssen, G. M., Lemmens, K. J. A., Ides, B., Vangrieken, P., Bouwman, F. G., Mariman, E. C., Pader, I., Arner, E. S. J., Johansson, K., Bast, A., & Haenen, G. R. M. M. (2017). Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress. Biochimica et Biophysica Acta-general Subjects, 1861(5), 1177-1189. https://doi.org/10.1016/j.bbagen.2017.03.004
Overview