Theses 2016

Strijkers R
Supervisors: Prof. C.H.A. Wittens, Prof. H. ten Cate | Co-supervisor: Dr A.J. ten Cate-Hoek
Title: Safety and Feasibility of Ultrasound Accelerated Catheter Directed Thrombolysis and the Postthrombotic Syndrome
13 January 2016
Roest A
Faculty of Health, Medicine and Life Sciences
Supervisor: Prof. C.D.A. Stehouwer | Co-supervisor: Dr P.M. Stassen
Title: Emergency Care in Sepsis Patients
13 January 2016
Nuzzo F
Supervisor: Prof. T. Hackeng | Co-supervisor: Dr E. Castoldi
Title: Coagulation factur V deficiency: From molecular diagnosis to molecular therapy
14 January 2016
Ševerdija E
Supervisor: Prof. J.G. Maessen | Co-supervisor: Dr P.W. Weerwind, Dr J.H. Heijmans
Title: Cerebral circulation and metabolic properties in patients undergoing normothermic cardiopulmonary bypass
28 January 2016
Mattheij N
Supervisor: Prof. J.W.M. Heemskerk  | Co-supervisor: Dr J.M.E.M. Cosemans
Title: Molecular mechanisms underlying the platelet Procoagulant response: back to basics
29 January 2016
Klarenbeek P
Supervisor: Prof. R.J. van Oostenbrugge | Co-supervisor: Dr J. Staals
Title: Blood pressure and cerebral small vessel disease
29 January 2016
IJzerman R
Supervisor: Prof. N.C. Schaper | Co-Supervisors: Dr H.H.C.M. Savelberg, Dr K. Meijer
Title: Muscle strength, mobility and quality of life in patients with diabetic polyneuropathy; the influence of a functional strength and gait training
5 February 2016
Bouman A
Supervisor: Prof. H. ten Cate | Co-Supervisors: Dr A.J. ten Cate-Hoek, Dr M.A. Joore 
Title: Post thrombotic syndrome, exploring aspects of pathophysiology and personalized management
18 February 2016
Truijman M
Supervisors: Prof. W.H. Mess, Prof. J.E. Wildberger | Co-Supervisor: Dr M.E. Kooi
Title: Plaque vulnerability in stroke patients: a multimodality imaging approach
19 February 2016
Rienks M
Supervisor: Prof. S. Heymans | Co-Supervisor: Dr A.P. Papageorgiou 
Title: Secreted Glycoproteins and Proteoglycans Orchestrate Inflammation in Cardiac Disease
26 February 2016
Klinkenberg L
Supervisor: Prof. M.P. van Dieijen-Visser, Prof. L. v. Loon | Co-supervisor: Dr S.J.R. Meex
Title: High-sensitivity cardiac troponins in health and disease
4 March 2016
Kaufmann B
Supervisor: Prof. H. Brunner-La Rocca | Co-supervisor: Dr V.P.M. van Empel
Title: Echocardiography – modern evaluation of cardiac structure and function
11 March 2016
Knackstedt C
Supervisor: Prof. H. Brunner-La Rocca | Co-supervisor: Dr V.P.M. van Empel
Title: Improvement of Technical Options Regarding Imaging and Therapy of Heart Failure
11 March 2016
Swieringa F
Supervisor: Prof. J.W.M. Heemskerk | Co-supervisor: Dr P.E.J. van der Meijden
Title: Platelets and Coagulation; Partners in haemostasis
31 March 2016
Hertle E
Supervisor: Prof. C.D.A. Stehouwer | Co-supervisors: Dr M.M.J. van Greevenbroek, Prof. I.C.W. Arts
Title: The complement system and cardiovascular disease: The codam study
1 April 2016
Vaes R
Supervisor: Prof. J.A.W. Teijink | Co-supervisors: Dr M.R.N. Scheltinga, Dr J.H. Tordoir
Title: Long term complications following elbow-based autogenous haemodialysis access: studies on high flow and hand ischemia
20 April 2016
Gharaviri A
Supervisor: Prof. U. Schotten | Co-supervisor: Dr S. Verheule
Title: Computer models of endo-epicardial dissociation of electrical activity and transmural conduction
29 April 2016
Hermans K
Supervisors: Prof. H. Struijker Boudier, Prof. P. Timmerman | Co-supervisor: Dr W. Blankesteijn
Title: Wnt/Frizzled Signaling in Myocardial Infarction; Characterization and Interventions with Peptide Fragments of Wnt
11 May 2016
Loeffen R
Supervisor: Prof. H. ten Cate | Co-supervisor: Dr H. Spronk
Title: Hypercoagulability in cardiovascular disease
13 May 2016
Marsch E
Supervisors: Prof. M. Daemen, Prof. E. Biessen | Co-supervisor: Dr J. Sluimer
Title: Hypoxia in Experimental Atherosclerosis - Linking Cellular Oxygen Sensors and Cholesterol Metabolism
18 May 2016
Theelen Th
Supervisors: Prof. M. Daemen, Prof. E. Biessen | Co-supervisor: Dr J. Sluimer
Title: The Role of Hypoxia and Vascular Growth Factors in Experimental Atherosclerosis
20 May 2016
Kremers R
Supervisors: Prof. H. ten Cate, Prof. H. Hemker | Co-supervisors: Dr R. Wagenvoord, Dr H. de Laat
Title: Thrombin dynamics
20 May 2016
Peters T
Supervisor: Prof. S. Heymans | Co-supervisor: Dr B. Schroen
Title: Non-coding RNA species in heart failure; regulators of cardiac hypertrophy, fibrosis and inflammation
1 June 2016
Derks W
Supervisors: Prof. S. Heymans, Prof. E. Lutgens | Co-supervisor: Dr M. van Bilsen
Title: Inflammation as orchestrator of cardiac disease progression
3 June 2016
van Anten M
Supervisors: Prof. J. Lodder, Prof. C. Bruggeman
Title: Chlamydia Pneumophyla and the risk of cerebral ischemia
3 June 2016
Chennupati R
Supervisors: Prof. J.G.R. De Mey, Prof. W.H. Lamers. | Co-supervisor: Dr S.E. Köhler
Title: Role of arginine metabolism in the production of endothelium- derived relaxing factors; effects of aging, hyperglycemia and hyperglycemia and hyperlipidemia
20 June 2016
Legein B
Supervisors: Prof. E. Biessen, Prof. E. Lutgens | Co-supervisor: Dr L. Temmerman
Title: Role of dendritic cell subsets in hyperlipidemia and atherosclerosis
23 June 2016
Berendsen B
Supervisors: Prof. H. Savelberg, Prof. N. Schaper | Co-supervisor: Dr M. Hendriks
Title: Measurement and promotion of physical activity; evaluation of activity monitoirs and a multidisciplinary lifestyle intervention in primary care
24 June 2016
van Twist D
Supervisors: Prof. P. de Leeuw, Prof. A. Kroon | Co-supervisor: Dr A. Houben
Title: The renin-angiotensin system in the hypertensive kidney; clinical studies in patients with essential hypertension, fibromuscular dysplasia, and the atherosclerotic renal artery stenosis
29 June 2016
Vries M
Supervisor: Prof. M.J. Post. | Co-supervisor: Dr D.G.M. Molin
Title: Cytokines in arteriogenesis from a therapeutic perspective
1 July 2016
van der Berg J
Supervisors: Prof. C.D.A. Stehouwer, Prof. H. Bosma. | Co-supervisor: Dr A. Koster
Title: Sedentary behavior and cardio-metabolic health; a study into the hazards of sitting too much
6 July 2016
Magdelijns F
Supervisor: Prof. C.D.A. Stehouwer. | Co-supervisors: Dr P.M. Stassen, Dr E. Pijpers
Title: Health-care-related adverse events leading to (re)hospitalization; how much do we really know?
7 July 2016
Liu Y
Supervisor: Prof. J.F.C. Glatz | Co-supervisors: Dr. J.J.F.P. Luiken, Dr D. Neumann
Title: v-ATPase is a key player in lipid-induced cardiomyopathy
13 September 2016
Mafi Rad M
Supervisors: Prof. H.J.G.M. Crijns, Prof. F.W. Prinzen | Co-supervisor: Dr K. Vernooy
Title: Mapping and prevention of cardiac dyssynchrony; Towards better substrate identification and lead implantation
16 September 2016
Vaidya A
Supervisors: Prof. J.L. Severens, Prof. H. ten Cate, Prof. M.A. Joore
Title: Economic modelling in arterial vascular diseases; Studying the cost-effectiveness of various strategies for screening, diagnosis and treatment
16 September 2016
Cluitmans M
Supervisors: Prof. P. Volders, Prof. R. Peeters, Prof. R. Westra
Title: Noninvasive reconstruction of cardiac electrical activity; Mathematical innovation, in vivo validation and human application
29 September 2016
Geijselaers S
Supervisors: Prof. C.D.A.Stehouwer, Prof. G.J. Biessels | Co-supervisor: Dr S.J.S. Sep
Title: Cognitive Dysfunction: At the crossroads of glucose metabolism and vascular function
5 October 2016
Kleinegris M
Supervisor: Prof. H. ten Cate | Co-supervisors: Dr A.J. ten Cate-Hoek, Dr G.H. Koek, Dr B. de Laat
Title: Coagulation testing in atherosclerosis and liver disease
21 October 2016

Daamen A
Supervisors: Prof. J.M.G.A. Schols, Prof. J.P.H. Hamers, Prof. H.P. Brunner-La Rocca
Title: Heart failure in nursing home residents; Prevalence, Diagnosis and treatment
12 October 2016
Engels E
Supervisor: Prof. F.W. Prinzen | Co-supervisor: Dr K. Vernooy
Title: Something old, something new: vectorcardiographic loop size and response to cardiac resynchronization therapy
19 October 2016
Spronck B
Supervisor: Prof. T. Delhaas. | Co-supervisors: Dr K.D. Reesink, Dr R.T.A. Megens, Munich
Title: Stiff vessels approached in a flexible way: Advancing quantification and interpretation of arterial stiffness
19 October 2016
Zhu X
Supervisor: Prof. J.F.C. Glatz | Co-supervisors: Dr D. Neumann, Dr J.W. Voncken
Title: The AMPK-MNK1 signaling axis
20 October 2016
Deckx S
Supervisor: Prof. S. Heymans | Co-supervisor: Dr A. Papageorgiou
Title: Matrix Glycoproteins and Proteoglycans are Paramount in cardiac disease
21 October 2016
Mastenbroek T
Supervisor: Prof. J.W.M. Heemskerk | Co-supervisor: Dr J.M.E.M. Cosemans
Title: Role of platelets in vascular remodeling: acute and persistent effects
27 October 2016
Burgmaier M
Supervisors: Prof. CP.M. Reutelingsperger, Prof. N. Marx, Aachen | Co-supervisor: Dr L. Schurgers
Title: From bench to bedside: Tools to diagnose and treat atherosclerosis and heart failure
8 November 2016
Lankveld T
Supervisors: Prof. U. Schotten, Prof. H.J.G.M. Crijns | Co-supervisor: Dr S. Zeemering
Title: Use of the electrocardiogram for prediction of arrhythmia outcome in atrial fibrillation
17 November 2016
Mihl C
Supervisor: Prof. J.E. Wildberger | Co-supervisors: Dr M. Das, Dr B.L.J.H. Kietselaer
Title: Decisive modification tools in coronary computed tomographic angiography; from phantom to patient
18 November 2016
Kok M
Supervisor: Prof. J.E. Wildberger | Co-supervisors: Dr M. Das, Dr B.L.J.H. Kietselaer
Title: Individual Optimisation of Contrast Media Application and Radiation Dose in Computed Tomographic Angiography; from Phantom to Patient
18 November 2016
Philippen L
Supervisor: Prof. L.J. De Windt | Co-supervisors: Dr P. Da Costa Martins, Dr E. Dirkx
Title: Non-coding RNAs in eccentric cardiac remodeling and heart failure
23 November 2016
Omarova F
Supervisors: Prof. J. Rosing, Prof. R.M. Bertina, UL | Co-supervisor: Dr E. Castoldi
Title: Primed to act: the effect of fibrinogen ‘Y’ on thrombin functions
24 November 2016
Kurstjens R
Supervisors: Prof. C.H.A. Wittens, Prof. J.E. Wildberger | Co-supervisor: Dr R. de Graaf
Title: Haemodynamics in Deep Venous Obstruction
14 December 2016
Karmann-Sailer A
Supervisors: Prof. G.W.H. Schurink, Prof. M.W. de Haan | Co-supervisor: Dr C. Jeukens
Title: Multimodal image fusion in endovascular complex aortic aneurysm repair
14 December 2016
Supervisor: Prof. T.M. Hackeng | Co-supervisor: Dr R. Koenen
Title: Oximation optimization and applications in cardiovascular research
15 December 2016