PhD candidate to develop and work on an experimental animal model of multi-morbidity focusing on disease interaction, disease progression and mental health including non-invasive multi-modal imaging.

26-07-2020

PhD Position

The PhD student will develop and work on an experimental animal model of multi-morbidity focusing on disease interaction, disease progression and mental health including non-invasive multi-modal imaging. The aim of the project is to develop and use a novel experimental animal model to study simultaneously cancer, atherosclerosis, vascular calcification and mental health in one animal.

The work will combine basic and translational science as well as imaging by using experimental animals to introduce a novel multi-morbid disease model. This model will be used to characterize disease-impact in depth and apply state-of-the-art imaging modalities. The candidate should have strong affinity with experimental animal research. Additionally, a background in molecular imaging (i.e. PET/ SPECT, MRI, CT) is a perquisite. Moreover, the candidate needs to have excellent communication skills as the PhD position is centered around the faculty of Health, Medicine and life sciences (FHML) and the schools of Cardiovascular disease (CARIM), school of Mental and Neurosciences (MHENS) and the institute of cancer research (MAASTRO).

We offer a position in one of the youngest and leading Universities in the field of vascular disease, cancer biology and neuroscience with an excellent network of international collaborators and longstanding experience in translational science.

The candidate should have a biomedical or molecular biology background and interest in complex pathophysiology of diseases of the cardiovascular system, cancer biology and the influence thereof on mental health. We are looking for a highly motivated person that is dedicated to work full time in the arena of experimental research and have the potential to work both independently and within a translational team. The daily work is laboratory-based and includes a number of in vivo and in vitro molecular techniques used in modern laboratories. Willingness to work with experimental animals is key and the required documents to work with experimental animals (Felasa B/C, Art 9) will be assessed as highly meritorious. Additional experience in bioinformatics analyses and tissue processing will be judged positive. 

The appointed person will be expected to plan, perform, analyze and interpret experimental results independently and within the Team, present at congresses, and participate in local and external collaboration networks. Willingness to work flexibly in order to achieve project demands and targets as agreed within a Team is necessary. Being able to organize and prioritize work, as well as organizing research within the project timetable is essential. Maintaining accurate and up to date records is necessary. Fluency in English is a requirement, knowledge of Dutch is not necessary but will be considered advantageous. Good social and analytical skills are essential.