Joachim Wildberger

Professor

Joachim Wildberger is full Professor of Radiology and Chairman of the Department of Radiology and Nuclear Medicine at Maastricht UMC+. In addition, he serves as Director of the Division of Clinical Imaging and Diagnostic Laboratories at Maastrcith UMC+.

Graduated at the Rhenian-Westphalian Technical University (RWTH) in Aachen, Germany, he received his medical degree in 1994. After internships in Cardiology and Diagnostic Radiology (Mönchengladbach/ Leipzig), he started his residency in Diagnostic Radiology at the University Hospital Aachen. He was board certified for Diagnostic Radiology in December 1998, and became a fellow/staff member at this department thereafter. He received his PhD in Radiology in 2002, was appointed as vice-chairman of the department in 2006 and received a professorship at the RWTH Aachen in 2007. In July 2007 he became Head of Department, Diagnostic Radiology, HELIOS Klinikum Berlin-Buch, Charité Berlin, Campus Buch, Germany, before moving to his present position.

His per personal research topics are technical developments and functional imaging in computed tomography, contrast media research, cardiac imaging as well as image-guided interventions.

As PI for Imaging within CARIM he focusses on translational research, integrating different imaging modalities into the cardiovascular diagnostic chain, and favours multidisciplinary approaches to improve patient care.

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 4.G2.013
T: +31(0)43 387 49 12

  • 2017
    • Nijssen, E. C., Nelemans, P. J., Rennenberg, R. J., van Ommen, V., Wildberger, J. E., & CIN Grp MUMC (2017). Hydration and contrast-induced kidney injury: Author's reply. Lancet, 390(10093), 454-455. https://doi.org/10.1016/S0140-6736(17)31809-3
    • Bucerius, J., Barthel, H., Tiepolt, S., Werner, P., Sluimer, J. C., Wildberger, J. E., Patt, M., Hesse, S., Gertz, H.-J., Biessen, E. A. L., Mottaghy, F. M., & Sabri, O. (2017). Feasibility of in vivo (18)F-florbetaben PET/MR imaging of human carotid amyloid-beta. European Journal of Nuclear Medicine and Molecular Imaging, 44(7), 1119-1128. https://doi.org/10.1007/s00259-017-3651-2
    • Nijssen, E. C., Nelemans, P. J., Rennenberg, R. J., Essers, B. A., Janssen, M. M., Vermeeren, M. A., van Ommen, V., & Wildberger, J. E. (2017). Intravenous hydration according to current guidelines in the prevention of contrast induced nephropathy-the AMACING trial. Journal of Thoracic Disease, 9(7), E656-E657. https://doi.org/10.21037/jtd.2017.06.80
    • van Hoof, R. H. M., Hermeling, E., Sluimer, J. C., Salzmann, J., Hoeks, A. P. G., Roussel, J., Daemen, M. J. A. P., Struijker-Boudier, H., Wildberger, J. E., Heeneman, S., & Kooi, M. E. (2017). Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits. PLOS ONE, 12(6), Article 0179024. https://doi.org/10.1371/journal.pone.0179024
    • Altintas, S., Dinh, T., Marcks, N. G. H. M., Kok, M., Aerts, A. J. J., Weijs, B., Blaauw, Y., Wildberger, J. E., Das, M., Kietselaer, B. L. J. H., & Crijns, H. J. G. M. (2017). Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope. Netherlands Heart Journal, 25(6), 376-387. https://doi.org/10.1007/s12471-017-0970-7
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J., Steinbusch, H. W. M., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. JFA. (2017). Cerebral pathology and cognition in diabetes: the merits of multiparametric neuroimaging. Frontiers in Neuroscience, 11, Article 188. https://doi.org/10.3389/fnins.2017.00188
    • Nijssen, E. C., Rennenberg, R. J., Nelemans, P. J., Essers, B. A., Janssen, M. M., Vermeeren, M. A., van Ommen, V., & Wildberger, J. E. (2017). Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet, 389(10076), 1312-1322. https://doi.org/10.1016/S0140-6736(17)30057-0
    • Mihl, C., Maas, M., Turek, J., Seehofnerova, A., Leijenaar, R. T. H., Kok, M., Lobbes, M. B. I., Wildberger, J. E., & Das, M. (2017). Contrast Media Administration in Coronary Computed Tomography Angiography - A Systematic Review. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren, 189(4), 312-325. https://doi.org/10.1055/s-0042-121609
    • Sailer, A. M., Paulis, L., Vergoossen, L., Kovac, A. O., Wijnhoven, G., Schurink, G. W. H., Mees, B., Das, M., Wildberger, J. E., de Haan, M. W., & Jeukens, C. R. L. P. N. (2017). Real-Time Patient and Staff Radiation Dose Monitoring in IR Practice. Cardiovascular and Interventional Radiology, 40(3), 421-429. https://doi.org/10.1007/s00270-016-1526-8
    • van Bussel, F. C. G., Backes, W. H., van Veenendaal, T. M., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Sep, S. J. S., Dagnelie, P. C., Schaper, N., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. F. A. (2017). Erratum: Functional Brain Networks Are Altered in Type 2 Diabetes and Prediabetes: Signs for Compensation of Cognitive Decrements? The Maastricht Study (vol 65, pg 2404, 2016). Diabetes, 66(2), 560. https://doi.org/10.2337/db17-er02a
    • Lindeboom, L., Bruls, Y. M. H., van Ewijk, P. A., Hesselink, M. K. C., Wildberger, J. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2017). Longitudinal relaxation time editing for acetylcarnitine detection with H-MRS. Magnetic Resonance in Medicine, 77(2), 505–510. https://doi.org/10.1002/mrm.26149
    • Houben, I. P. L., van Berlo, C. J. L. Y., Bekers, O., Nijssen, E. C., Lobbes, M. B. I., & Wildberger, J. E. (2017). Assessing the Risk of Contrast-Induced Nephropathy Using a Finger Stick Analysis in Recalls from Breast Screening: The CINFIBS Explorative Study. Contrast Media & Molecular Imaging, Article 5670384. https://doi.org/10.1155/2017/5670384
    • van Hoof, R. H. M., Schreuder, F. H. B. M., Nelemans, P., Truijman, M. T. B., van Orshoven, N. P., Schreuder, T. H., Mess, W. H., Heeneman, S., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2017). Ischemic Stroke Patients Demonstrate Increased Carotid Plaque Microvasculature Compared to (Ocular) Transient Ischemic Attack Patients. Cerebrovascular Diseases, 44(5-6), 297-303. https://doi.org/10.1159/000481146
  • 2016
    • Jansen, J., van Bussel, F. C. G., van de Haar, H. J., van Osch, M. J. P., Hofman, P. A. M., van Boxtel, M. P. J., van Oostenbrugge, R. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Backes, W. H. (2016). Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus. Scientific Reports, 6(1), Article 10. https://doi.org/10.1038/s41598-016-0003-6
    • Lalji, U. C., Houben, I. P. L., Prevos, R., Gommers, S., van Goethem, M., Vanwetswinkel, S., Pijnappel, R., Steeman, R., Frotscher, C., Mok, W., Nelemans, P., Smidt, M. L., Beets-Tan, R. G., Wildberger, J. E., & Lobbes, M. B. I. (2016). Contrast-enhanced spectral mammography in recalls from the Dutch breast cancer screening program: validation of results in a large multireader, multicase study. European Radiology, 26(12), 4371-4379. https://doi.org/10.1007/s00330-016-4336-0
    • Kok, M., Mihl, C., Hendriks, B. M. F., Altintas, S., Eijsvoogel, N. G., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Patient Comfort During Contrast Media Injection in Coronary Computed Tomographic Angiography Using Varying Contrast Media Concentrations and Flow Rates Results From the EICAR Trial. Investigative Radiology, 51(12), 810-815. https://doi.org/10.1097/RLI.0000000000000284
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., Puts, N. A. J., Edden, R. A. E., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. (2016). Increased GABA concentrations in type 2 diabetes mellitus are related to lower cognitive functioning. Medicine, 95(36), Article e4803. https://doi.org/10.1097/MD.0000000000004803
    • Lindeboom, L., de Graaf, R. A., Nabuurs, C. I., van Ewijk, E., Hesselink, M. K. C., Wildberger, J. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2016). Quantum coherence spectroscopy to measure dietary fat retention in the liver. JCI INSIGHT, 1(13), Article e84671. https://doi.org/10.1172/jci.insight.84671
    • van Bussel, F. C. G., Backes, W. H., van Veenendaal, T. M., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Sep, S. J. S., Dagnelie, P. C., Schaper, N., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. (2016). Functional brain networks are altered in type 2 diabetes and pre-diabetes signs for compensation of cognitive decrements? - The Maastricht Study: signs for compensation of cognitive decrements? - The Maastricht Study. Diabetes, 65(8), 2404-2413. https://doi.org/10.2337/db16-0128
    • Kok, M., Turek, J., Mihl, C., Reinartz, S. D., Gohmann, R. F., Nijssen, E. C., Kats, S., van Ommen, V. G. V. A., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Low contrast media volume in pre-TAVI CT examinations. European Radiology, 26(8), 2426-2435. https://doi.org/10.1007/s00330-015-4080-x
    • Smulders, M. W., Kietselaer, B. L. J. H., Schalla, S., Bucerius, J., Jaarsma, C., van Dieijen-Visser, M. P., Mingels, A. M. A., Brunner-La Rocca, H., Post, M., Das, M., Crijns, H. J. G. M., Wildberger, J. E., & Bekkers, B. (2016). Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging?American Heart Journal, 177, 102-111. https://doi.org/10.1016/j.ahj.2016.03.025
    • Das, M., & Wildberger, J. E. (2016). Diagnostik der akuten Lungenembolie. Der Radiologe, 56(6), 543-554. https://doi.org/10.1007/s00117-016-0100-3
    • van Hoof, R. H. M., Heeneman, S., Wildberger, J. E., & Kooi, E. (2016). Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature. Current Atherosclerosis Reports, 18(6), Article 33. https://doi.org/10.1007/s11883-016-0583-4
    • Kok, M., Mihl, C., Hendriks, B. M. F., Altintas, S., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Optimizing contrast media application in coronary CT angiography at lower tube voltage: Evaluation in a circulation phantom and sixty patients. European Journal of Radiology, 85(6), 1068-1074. https://doi.org/10.1016/j.ejrad.2016.03.022
    • Cardinaels, E. P. M., Altintas, S., Versteylen, M. O., Joosen, I. A., Jellema, L.-J. C., Wildberger, J. E., Das, M., Crijns, H. J., Bekers, O., van Dieijen-Visser, M. P., Kietselaer, B. L., & Mingels, A. M. A. (2016). High-Sensitivity Cardiac Troponin Concentrations in Patients with Chest Discomfort: Is It the Heart or the Kidneys As Well?PLOS ONE, 11(4), Article e0153300. https://doi.org/10.1371/journal.pone.0153300
    • Kemerink, G. J., van Engelshoven, J., Simon, K. J., Kutterer, G., & Wildberger, J. E. (2016). Early X-ray workers: an effort to assess their numbers, risk, and most common (skin) affliction. Insights into Imaging, 7(2), 275-282. https://doi.org/10.1007/s13244-015-0457-2
    • Mihl, C., Kok, M., Altintas, S., Kietselaer, B. L. J. H., Turek, J., Wildberger, J. E., & Das, M. (2016). Evaluation of individually body weight adapted contrast media injection in coronary CT-angiography. European Journal of Radiology, 85(4), 830-836. https://doi.org/10.1016/j.ejrad.2015.12.031
    • Kok, M., de Haan, M., Mihl, C., Eijsvoogel, N. G., Hendriks, B. M. F., Sailer, A. M., Derks, K., Schnerr, R. S., Schurink, G., Wildberger, J. E., & Das, M. (2016). Individualized CT Angiography Protocols for the Evaluation of the Aorta: A Feasibility Study. Journal of Vascular and Interventional Radiology, 27(4), 531-538. https://doi.org/10.1016/j.jvir.2016.01.009
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. F. A. (2016). Altered Hippocampal White Matter Connectivity in Type 2 Diabetes Mellitus and Memory Decrements. Journal of Neuroendocrinology, 28(3), Article 12366. https://doi.org/10.1111/jne.12366
    • van Elmpt, W., Zegers, K., Reymen, B., Even, A. J. G., Dingemans, A.-M. C., Öllers, M., Wildberger, J. E., Mottaghy, F. M., Das, M., Troost, E. G. C., & Lambin, P. (2016). Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion. European Journal of Nuclear Medicine and Molecular Imaging, 43(2), 240-248. https://doi.org/10.1007/s00259-015-3169-4
    • Landry, G., Gaudreault, M., van Elmpt, W., Wildberger, J. E., & Verhaegen, F. (2016). Improved dose calculation accuracy for low energy brachytherapy by optimizing dual energy CT imaging protocols for noise reduction using sinogram affirmed iterative reconstruction. Zeitschrift für Medizinische Physik, 26(1), 75-87. https://doi.org/10.1016/j.zemedi.2015.09.001
    • Hendriks, B. M. F., Kok, M., Mihl, C., Bekkers, B., Wildberger, J. E., & Das, M. (2016). Individually tailored contrast enhancement in CT pulmonary angiography. British Journal of Radiology, 89(1061), Article 20150850. https://doi.org/10.1259/bjr.20150850
    • Altintas, S., Cardinaels, E., Versteylen, M. O., Joosen, I. A., Seifert, H., Wildberger, J. E., Crijns, H. J., Nelemans, P. J., van Dieijen - Visser, M. P., Mingels, A. M. A., Das, M., & Kietselaer, B. L. (2016). Unstable coronary plaque characteristics are associated with high sensitivity cardiac troponin T and N-terminal Pro-Brain Natriuretic Peptide. Journal of Cardiovascular Computed Tomography, 10(1), 82-88. https://doi.org/10.1016/j.jcct.2015.10.001
  • 2015
    • Kok, M., Mihl, C., Seehofnerova, A., Turek, J., Jost, G., Pietsch, H., Haberland, U., Wildberger, J. E., & Das, M. (2015). Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate. American Journal of Roentgenology, 205(6), 1332-1338. https://doi.org/10.2214/AJR.14.13957
    • Sailer, A. M., van Zwam, W. H., Wildberger, J. E., & Grutters, J. P. C. (2015). Cost-effectiveness modelling in diagnostic imaging: a stepwise approach. European Radiology, 25(12), 3629-3637. https://doi.org/10.1007/s00330-015-3770-8
    • Lalji, U. C., Wildberger, J. E., Hausen, A. Z., Bendek, M., Dingemans, A.-M. C., Hochstenbag, M., & Das, M. (2015). CT-Guided Percutaneous Transthoracic Needle Biopsies Using 10G Large-Core Needles: Initial Experience. Cardiovascular and Interventional Radiology, 38(6), 1603-1610. https://doi.org/10.1007/s00270-015-1098-z
    • Mihl, C., Kok, M., Wildberger, J. E., Altintas, S., Labus, D., Nijssen, E. C., Hendriks, B. M. F., Kietselaer, B. L. J. H., & Das, M. (2015). Coronary CT angiography using low concentrated contrast media injected with high flow rates: Feasible in clinical practice. European Journal of Radiology, 84(11), 2155-2160. https://doi.org/10.1016/j.ejrad.2015.06.031
    • Hansen, D. C., Seco, J., Sorensen, T. S., Petersen, J. B. B., Wildberger, J. E., Verhaegen, F., & Landry, G. (2015). A simulation study on proton computed tomography ( CT) stopping power accuracy using dual energy CT scans as benchmark. Acta Oncologica, 54(9), 1638-1642. https://doi.org/10.3109/0284186X.2015.1061212
    • Lalji, U. C., Jeukens, C. R. L. P. N., Houben, I., Nelemans, P. J., van Engen, R. E., van Wylick, E., Beets-Tan, R. G. H., Wildberger, J. E., Paulis, L. E., & Lobbes, M. B. I. (2015). Evaluation of low-energy contrast-enhanced spectral mammography images by comparing them to full-field digital mammography using EUREF image quality criteria. European Radiology, 25(10), 2813-2820. https://doi.org/10.1007/s00330-015-3695-2
    • Paulis, L. E., Lobbes, M. B. I., Lalji, U. C., Gelissen, N., Bouwman, R. W., Wildberger, J. E., & Jeukens, C. R. L. P. N. (2015). Radiation Exposure of Digital Breast Tomosynthesis Using an Antiscatter Grid Compared With Full-Field Digital Mammography. Investigative Radiology, 50(10), 679-685. https://doi.org/10.1097/RLI.0000000000000168
    • Lell, M. M., Wildberger, J. E., Alkadhi, H., Damilakis, J., & Kachelriess, M. (2015). Evolution in Computed Tomography The Battle for Speed and Dose. Investigative Radiology, 50(9), 629-644. https://doi.org/10.1097/RLI.0000000000000172
    • Kim, H., Park, C. M., Goo, J. M., Wildberger, J. E., & Kauczor, H.-U. (2015). Quantitative Computed Tomography Imaging Biomarkers in the Diagnosis and Management of Lung Cancer. Investigative Radiology, 50(9), 571-583. https://doi.org/10.1097/RLI.0000000000000152
    • PROVIDI Study Grp, & Wildberger, J. (2015). Incidental findings on chest CT imaging are associated with increased COPD exacerbations and mortality. Thorax, 70(8), 725-731. https://doi.org/10.1136/thoraxjnl-2014-206160
    • Sailer, A. M., Schurink, G. W. H., Bol, M. E., de Haan, M. W., van Zwam, W. H., Wildberger, J. E., & Jeukens, C. R. L. P. N. (2015). Occupational Radiation Exposure During Endovascular Aortic Repair. Cardiovascular and Interventional Radiology, 38(4), 827-832. https://doi.org/10.1007/s00270-014-1025-8
    • van Hoof, R. H. M., Hermeling, E., Truijman, M. T. B., van Oostenbrugge, R. J., Daemen, J. W. H., van der Geest, R. J., van Orshoven, N. P., Schreuder, A. H., Backes, W. H., Daemen, M. J. A. P., Wildberger, J. E., & Kooi, M. E. (2015). Phase-based vascular input function: Improved quantitative DCE-MRI of atherosclerotic plaques. Medical Physics, 42(8), 4619-4628. https://doi.org/10.1118/1.4924949
    • Mihl, C., Kok, M., Wildberger, J. E., Turek, J., Muehlenbruch, G., & Das, M. (2015). Computed Tomography Angiography With High Flow Rates An In Vitro and In Vivo Feasibility Study. Investigative Radiology, 50(7), 464-469. https://doi.org/10.1097/RLI.0000000000000153
    • Jurencak, T., Turek, J., Kietselaer, B., Mihl, C., Kok, M., van Ommen, V. G. V. A., van Garsse, L. A. F. M., Nijssen, E. C., Wildberger, J. E., & Das, M. (2015). MDCT evaluation of aortic root and aortic valve prior to TAVI. What is the optimal imaging time point in the cardiac cycle?European Radiology, 25(7), 1975-1983. https://doi.org/10.1007/s00330-015-3607-5
    • Kok, M., Kietselaer, B. L. J. H., Mihl, C., Altintas, S., Nijssen, E. C., Wildberger, J. E., & Das, M. (2015). Contrast Enhancement of the Right Ventricle during Coronary CT Angiography - Is It Necessary?PLOS ONE, 10(6), Article e0128625. https://doi.org/10.1371/journal.pone.0128625
    • Providi Study Group, & Wildberger, J. (2015). Cardiovascular disease prediction: do pulmonary disease-related chest CT features have added value?European Radiology, 25(6), 1646-1654. https://doi.org/10.1007/s00330-014-3495-0
    • van Bussel, F. C., Backes, W. H., Hofman, P. A., van Oostenbrugge, R. J., Kessels, A. G., van Boxtel, M. P., Schram, M. T., Stehouwer, C. D., Wildberger, J. E., & Jansen, J. F. (2015). On the Interplay of Microvasculature, Parenchyma, and Memory in Type 2 Diabetes. Diabetes Care, 38(5), 876-882. https://doi.org/10.2337/dc14-2043