Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

 

  • 2024
    • Ceulemans, A., Spronk, H. M. H., Ten Cate, H., van Zwam, W. H., van Oostenbrugge, R. J., & Nagy, M. (2024). Current and potentially novel antithrombotic treatment in acute ischemic stroke. Thrombosis Research, 236, 74-84. https://doi.org/10.1016/j.thromres.2024.02.009
    • Kaesmacher, J., Cavalcante, F., Kappelhof, M., Treurniet, K. M., Rinkel, L., Liu, J., Yan, B., Zi, W., Kimura, K., Eker, O. F., Zhang, Y., Piechowiak, E. I., van Zwam, W., Liu, S., Strbian, D., Uyttenboogaart, M., Dobrocky, T., Miao, Z., Suzuki, K., ... IRIS Collaborators (2024). Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke: A Meta-Analysis. JAMA-Journal of the American Medical Association, 331(9), 764-777. https://doi.org/10.1001/jama.2024.0589
    • Knapen, R. R. M. M., Frol, S., van Kuijk, S. M. J., Oblak, J. P., van der Leij, C., van Oostenbrugge, R. J., & van Zwam, W. H. (2024). Intravenous thrombolysis for ischemic stroke in the posterior circulation: A systematic review and meta-analysis. Journal of Stroke and Cerebrovascular Diseases , 33(5), Article 107641. Advance online publication. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107641
    • Voorter, P. H. M., van Dinther, M., Jansen, W. J., Postma, A. A., Staals, J., Jansen, J. F. A., van Oostenbrugge, R. J., van der Thiel, M. M., & Backes, W. H. (2024). Blood-Brain Barrier Disruption and Perivascular Spaces in Small Vessel Disease and Neurodegenerative Diseases: A Review on MRI Methods and Insights. Journal of Magnetic Resonance Imaging, 59(2), 397-411. Article jmri28989. https://doi.org/10.1002/jmri.28989
    • Knapen, R. R. M. M., Pirson, F. A. V., Langezaal, L. C. M., Brouwer, J., Majoie, C. B. L. M., Emmer, B. J., Vos, J.-A., van Doormaal, P.-J., Yoo, A. J., Bruggeman, A. A. E., Lycklama À Nijeholt, G. J., van der Leij, C., van Oostenbrugge, R. J., van Zwam, W. H., Schonewille, W. J., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Hinsenveld, W., Staals, J., ... Pirson, A.-F. (2024). Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study. Stroke, 55(2), 403-412. https://doi.org/10.1161/STROKEAHA.123.043777
    • Verburgt, E., Hilkens, N. A., Ekker, M. S., Schellekens, M. M. I., Boot, E. M., Immens, M. H. M., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., van Tuijl, J. H., de Laat, K. F., van Norden, A. G. W., Vermeer, S. E., van Zagten, M. S. G., van Oostenbrugge, R. J., ... Verhoeven, J. I. (2024). Short-Term and Long-Term Risk of Recurrent Vascular Event by Cause After Ischemic Stroke in Young Adults. Jama network open, 7(2), Article 240054. https://doi.org/10.1001/jamanetworkopen.2024.0054
    • Pinckaers, F. M. E., Grutters, J. P. C., Huijberts, I., Gabrio, A., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Evers, S. M. A. A. (2024). Cost- and Utility Estimates per Modified Rankin Scale-Score up to 2 Years Post-Stroke: Data to Inform Economic Evaluations from a Societal Perspective. Value in Health. Advance online publication. https://doi.org/10.1016/j.jval.2024.01.001
    • van Voorst, H., Pitkanen, J., van Poppel, L., de Vries, L., Mojtahedi, M., Martou, L., Emmer, B. J., Roos, Y. B. W. E. M., van Oostenbrugge, R., Postma, A. A., Marquering, H. A., Majoie, C. B. L. M., Curtze, S., Melkas, S., Bentley, P., Caan, M. W. A., CONTRAST Consortium Collaborators, & MR CLEAN No IV (2024). Deep learning-based white matter lesion volume on CT is associated with outcome after acute ischemic stroke. European Radiology. Advance online publication. https://doi.org/10.1007/s00330-024-10584-z
    • van Dinther, M. M., Hooghiemstra, A. E., Bron, E., Versteeg, A. E., Leeuwis, A., Kalay, T. E., Moonen, J., Kuipers, S. H., Backes, W., Jansen, J. F. A., van Osch, M. J. P., Biessels, G.-J., Staals, J. J., van Oostenbrugge, R., & Heart-Brain Connection Consortium (2024). Lower cerebral blood flow predicts cognitive decline in patients with vascular cognitive impairment. Alzheimer's & Dementia, 20(1), 136-144. https://doi.org/10.1002/alz.13408
  • 2023
    • Schellekens, M. M. I., Springer, R. C. S., Boot, E. M., Verhoeven, J. I., Ekker, M. S., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., van Tuijl, J. H., de Laat, K. F., van Norden, A. G. W., Vermeer, S. E., van Zagten, M. S. G., Van Oostenbrugge, R. J., Wermer, M. J. H., ... Tuladhar, A. M. (2023). Cognitive trajectory in the first year after first-ever ischaemic stroke in young adults: the ODYSSEY study. Journal of Neurology Neurosurgery and Psychiatry. Advance online publication. https://doi.org/10.1136/jnnp-2023-332104
    • Pinckaers, F. M., Evers, S. M., Olthuis, S. G., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Grutters, J. P. (2023). Cost-effectiveness of endovascular treatment after 6-24?h in ischaemic stroke patients with collateral flow on CT-angiography: A model-based economic evaluation of the MR CLEAN-LATE trial. European Stroke Journal. Advance online publication. https://doi.org/10.1177/23969873231220464
    • Oestreich, L. K., Lo, J. W., Di Biase, M. A., Sachdev, P. S., Mok, A. H., Wright, P., Crawford, J. D., Lam, B., Traykov, L., Köhler, S., Staals, J. E., van Oostenbrugge, R., Chen, C., Desmond, D. W., Yu, K.-H., Lee, M., Klimkowicz-Mrowiec, A., Bordet, R., O'Sullivan, M. J., & Zalesky, A. (2023). Network analysis of neuropsychiatric, cognitive, and functional complications of stroke: implications for novel treatment targets. Psychiatry and Clinical Neurosciences. Advance online publication. https://doi.org/10.1111/pcn.13633
    • Robbe, M. M. Q., Pinckaers, F. M. E., Olthuis, S. G. H., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2023). Procedural Blood Pressure and Intracranial Hemorrhage on Dual-Energy Computed Tomography After Endovascular Stroke Treatment. Cardiovascular and Interventional Radiology. Advance online publication. https://doi.org/10.1007/s00270-023-03619-3
    • Van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H., Marquering, H. A., De Jong, H. W. A. M., Berkhemer, O. A., Van Zwam, W. H., Van Walderveen, M. A. A., Van Den Wijngaard, I. R., Dippel, D. W. J., Yoo, A. J., Campbell, B., Kunz, W. G., Majoie, C. B., Emmer, B. J., ... MR CLEAN Registry Investigators (2023). Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation. Journal of Neurology Neurosurgery and Psychiatry. Advance online publication. https://doi.org/10.1136/jnnp-2023-331862
    • Pinckaers, F. M. E., Robbe, M. M. Q., Olthuis, S. G. H., Boogaarts, H. D., van Zwam, W. H., van Oostenbrugge, R. J., & Postma, A. A. (2023). Prognostic Implications of Intracranial Haemorrhage on Dual-Energy CT Immediately Following Endovascular Treatment for Acute Ischemic Stroke. Journal of Neuroradiology. Advance online publication. https://doi.org/10.1016/j.neurad.2023.11.003
    • Bakker, L., Ramakers, I. H. G. B., J P M Eussen, S., Choe, K., van den Hove, D. L. A., Kenis, G., Rutten, B. P. F., van Oostenbrugge, R. J., Staals, J., Ulvik, A., Ueland, P. M., Verhey, F. R. J., & Köhler, S. (2023). The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study. Journal of the neurological sciences, 454(1), Article 120819. https://doi.org/10.1016/j.jns.2023.120819
    • Barlinn, K., Langezaal, L. C. M., Dippel, D. W. J., Van, W. H., Roessler, M., Roos, Y. B. W. E. M., Emmer, B. J., van Oostenbrugge, R. J., Gerber, J. C., Yoo, A. J., Pontes-Neto, O. M., Mazighi, M., Audebert, H. J., Michel, P., Schonewille, W. J., Puetz, V., & BASICS Study Group (2023). Early Intubation in Endovascular Therapy for Basilar Artery Occlusion: A Post Hoc Analysis of the BASICS Trial. Stroke, 54(11), 2745-2754. https://doi.org/10.1161/STROKEAHA.123.043669
    • Kopczak, A., Stringer, M. S., van den Brink, H., Kerkhofs, D., Blair, G. W., van Dinther, M., Reyes, C. A., Garcia, D. J., Onkenhout, L., Wartolowska, K. A., Thrippleton, M. J., Kampaite, A., Duering, M., Staals, J., Lesnik-Oberstein, S., Muir, K. W., Middeke, M., Norrving, B., Bousser, M. G., ... TREAT-SVDs collaborators (2023). Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial. Lancet Neurology, 22(11), 991-1004. https://doi.org/10.1016/S1474-4422(23)00293-4
    • Kassem, M., Crombag, G. A. J. C., Stegers, J., Liem, M. I., Koornstra, E., Schreuder, F. H. B. M., van Dam-Nolen, D. H. K., Lucci, C., van der Geest, R. J., Daemen, M. J., van der Steen, A. F. W., Hendrikse, J., Mess, W. H., Bos, D., Wildberger, J. E., van Oostenbruggeb, R. J., Nederkoorn, P. J., & Kooi, M. E. (2023). The association between antiplatelet therapy and changes in intraplaque hemorrhage in patients with mild to moderate symptomatic carotid stenosis: a longitudinal MRI study. Cerebrovascular Diseases. Advance online publication. https://doi.org/10.1159/000535274
    • Kassem, M., de Kam, S. S., van Velzen, T. J., van der Geest, R., Wagner, B., Sokolska, M., Pizzini, F. B., Nederkoorn, P. J., Rolf Jäger, H., Brown, M. M., van Oostenbrugge, R. J., Bonati, L. H., & Eline Kooi, M. (2023). Application of mask images of contrast-enhanced MR angiography to detect carotid intraplaque hemorrhage in patients with moderate to severe symptomatic and asymptomatic carotid stenosis. European Journal of Radiology, 168(1), Article 111145. https://doi.org/10.1016/j.ejrad.2023.111145
    • Berends, E., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2023). Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity. Fluids and barriers of the CNS, 20(1), Article 75. https://doi.org/10.1186/s12987-023-00477-6
    • Vos, E. M., Kappelhof, M., den Hartog, S. J., Coutinho, J. M., Emmer, B. J., Roozenbeek, B., van Zwam, W. H., van Oostenbrugge, R. J., van der Worp, H. B., Uyttenboogaart, M., van Es, A. C. G. M., Majoie, C. B. L. M., Dippel, D. W. J., Peeters-Scholte, C. M. P. C. D., van den Wijngaard, I. R., & MR CLEAN Registry Investigators (2023). Endovascular treatment of patients with stroke caused by anterior cerebral artery occlusions. Acta neurologica Belgica. Advance online publication. https://doi.org/10.1007/s13760-023-02395-8
    • Elschot, E. P., Backes, W. H., de Jong, J. J. A., Drenthen, G. S., Wong, S. M., Staals, J., Postma, A. A., Rouhl, R. P. W., van Oostenbrugge, R. J., & Jansen, J. F. A. (2023). Assessment of the clinical feasibility of detecting subtle blood-brain barrier leakage in cerebral small vessel disease using dynamic susceptibility contrast MRI. Magnetic Resonance Imaging, 102(1), 55-61. https://doi.org/10.1016/j.mri.2023.04.004
    • Voorter, P. H. M., Backes, W. H., Gurney-Champion, O. J., Wong, S.-M., Staals, J., van Oostenbrugge, R. J., van Der Thiel, M. M., Jansen, J. F. A., & Drenthen, G. S. (2023). Improving microstructural integrity, interstitial fluid, and blood microcirculation images from multi-b-value diffusion MRI using physics-informed neural networks in cerebrovascular disease. Magnetic Resonance in Medicine, 90(4), 1657 - 1671. https://doi.org/10.1002/mrm.29753
    • van der Steen, W., van der Ende, N. A. M., Luijten, S. P. R., Rinkel, L. A., van Kranendonk, K. R., van Voorst, H., Roosendaal, S. D., Beenen, L. F. M., Coutinho, J. M., Emmer, B. J., van Oostenbrugge, R. J., Majoie, C. B. L. M., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., MR CLEAN-NO IV Investigators, MR CLEAN-MED investigators, & CONTRAST Investigators (2023). Type of intracranial hemorrhage after endovascular stroke treatment: association with functional outcome. Journal of Neurointerventional Surgery, 15(10), 971-976. https://doi.org/10.1136/jnis-2022-019474
    • van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H. F., Beenen, L. F. M., de Jong, H. W. A. M., Berkhemer, O. A., van Zwam, W. H., Roos, Y. B. W. E. M., van Walderveen, M. A. A., van den Wijngaard, I., Dippel, D. W. J., Yoo, A. J., Campbell, B. C. V., Kunz, W. G., Emmer, B. J., ... MR CLEAN Registry Investigators (2023). Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study. European Radiology. Advance online publication. https://doi.org/10.1007/s00330-023-10119-y
    • Huijberts, I., Pinckaers, F. M. E., van Zwam, W. H., Boogaarts, H. D., van Oostenbrugge, R. J., & Postma, A. A. (2023). Cerebral Arterial Air Emboli on Immediate Post-Endovascular Treatment CT are Associated with Poor Short- and Long-Term Clinical Outcomes in Acute Ischemic Stroke Patients. Journal of Neuroradiology, 50(5), 530-536. https://doi.org/10.1016/j.neurad.2023.06.001
    • Exalto, L. G., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H.-J., Best, J. G., Bordet, R., Chen, C. P. L. H., van der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Huenges Wajer, I. M. C., Kim, J., Kappelle, L. J., Kim, B. J., Köhler, S., de Kort, P. L. M., ... Biessels, G. J. (2023). Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke. Stroke, 54(9), 2296-2303. https://doi.org/10.1161/STROKEAHA.123.042507
    • Kassem, M., Nies, K. P. H., Boswijk, E., van der Pol, J., Aizaz, M., Gijbels, M. J. J., Li, D., Bucerius, J., Mess, W. H., Wildberger, J. E., van Oostenbrugge, R. J., Moonen, R. P. M., Fan, Z., & Kooi, M. E. (2023). Quantification of carotid plaque composition with a multi-contrast atherosclerosis characterization (MATCH) MRI sequence. Frontiers in Cardiovascular Medicine, 10, Article 1227495. https://doi.org/10.3389/fcvm.2023.1227495
    • Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5
    • Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445
    • Knapen, R. R. M. M., Bernsen, M. L. E., Langezaal, L. C. M., Olthuis, S. G. H., Michel, P., Hofmeijer, J., Vos, J.-A., van Kuijk, S. M. J., Majoie, C. B., Emmer, B. J., Nijeholt, G. J. L. A., Boiten, J., Puetz, V., Gerber, J., Mazighi, M., Pontes-Neto, O. M., Mont'Alverne, F., Yoo, A. J., van Doormaal, P.-J., ... Schonewille, W. J. (2023). Aspiration Versus Stent Retriever Thrombectomy in Basilar-Artery Occlusion; Results From the BASICS Trial. Stroke: vascular and interventional neurology, 3(4), Article e000768. https://doi.org/10.1161/SVIN.122.000768
    • van den Berg, L. A., Berkhemer, O., Fransen, P. S. S., Beumer, D., Majoie, C. B. L., Dippel, D. W. J., van der Lugt, A. J., van Oostenbrugge, R. H., van Zwam, W. B., Roos, Y., Dijkgraaf, M. G. W., & MR CLEAN Investigators (2023). Budget impact of endovascular treatment for acute ischaemic stroke patients in the Netherlands for 2015-2021. Netherlands Heart Journal, 31(6), 254-259. https://doi.org/10.1007/s12471-023-01788-x
    • Pinckaers, F. M., Mentink, M. M., Boogaarts, H. D., van Zwam, W. H., van Oostenbrugge, R. J., & Postma, A. A. (2023). Early post-endovascular treatment contrast extravasation on dual-energy CT is associated with clinical and radiological stroke outcomes: A 10-year single-centre experience. European Stroke Journal, 8(2), 508-516. https://doi.org/10.1177/23969873231157901
    • van den Kerkhof, M., van der Thiel, M. M., van Oostenbrugge, R. J., Postma, A. A., Kroon, A. A., Backes, W. H., & Jansen, J. F. (2023). Impaired damping of cerebral blood flow velocity pulsatility is associated with the number of perivascular spaces as measured with 7T MRI. Journal of Cerebral Blood Flow and Metabolism, 43(6), 937-946. https://doi.org/10.1177/0271678X231153374
    • Benali, F., Kappelhof, M., Ospel, J., Ganesh, A., McDonough, R. V., Postma, A. A., Goldhoorn, R.-J. B., Majoie, C. B. L. M., van den Wijngaard, I., Lingsma, H. F., Vos, J. A., van Oostenbrugge, R. J., van Zwam, W. H., Goyal, M., & MR CLEAN Registry Investigators (2023). Benefit of successful reperfusion achieved by endovascular thrombectomy for patients with ischemic stroke and moderate pre-stroke disability (mRS 3): results from the MR CLEAN Registry. Journal of Neurointerventional Surgery, 15(5), 433-438. https://doi.org/10.1136/neurintsurg-2022-018853
    • Olthuis, S. G. H., Pirson, F. A. V., Pinckaers, F. M. E., Hinsenveld, W. H., Nieboer, D., Ceulemans, A., Knapen, R. R. M. M., Robbe, M. M. Q., Berkhemer, O. A., van Walderveen, M. A. A., Lycklama À Nijeholt, G. J., Uyttenboogaart, M., Schonewille, W. J., van der Sluijs, P. M., Wolff, L., van Voorst, H., Postma, A. A., Roosendaal, S. D., van der Hoorn, A., ... MR CLEAN-LATE Investigators (2023). Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial. Lancet, 401(10385), 1371-1380. https://doi.org/10.1016/S0140-6736(23)00575-5
    • van den Kerkhof, M., van der Thiel, M. M., Postma, A. A., van Oostenbrugge, R. J., Kroon, A. A., Jansen, J. F. A., & Backes, W. H. (2023). Hypertension Correlates With Stronger Blood Flow Pulsatility in Small Perforating Cerebral Arteries Assessed With 7 Tesla Magnetic Resonance Imaging. Hypertension, 80(4), 802-810. https://doi.org/10.1161/HYPERTENSIONAHA.122.19866
    • Terreros, N. A., Bruggeman, A. A. E., van Voorst, H., Konduri, P. R., Jansen, I. G. H., Kappelhof, M., Tolhuisen, M. L., Boodt, N., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., van der Worp, H. B., Emmer, B. J., Meijer, F. J. A., Roos, Y. B. W. E. M., van Bavel, E., Marquering, H. A., & Majoie, C. B. L. M. (2023). Bifurcation occlusions and endovascular treatment outcome in acute ischemic stroke. Journal of Neurointerventional Surgery, 15(4), 355-362. https://doi.org/10.1136/neurintsurg-2021-018560
    • Olthuis, S. G. H., Hinsenveld, W. H., Pinckaers, F. M. E., Amini, M., Lingsma, H. F., Staals, J., Schreuder, T. H. C. M. L., Schonewille, W. J., Yo, L. S. F., Roos, Y. B. W. E. M., Postma, A. A., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., de Ridder, I. R., & MR CLEAN Registry Investigators (2023). Association between type of intervention center and outcomes after endovascular treatment for acute ischemic stroke: Results from the MR CLEAN Registry. European Stroke Journal, 8(1), 224-230. https://doi.org/10.1177/23969873221145771
    • Bourcier, R., Goyal, M., Muir, K. W., Desal, H., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., Jovin, T. G., Mitchell, P. J., Demchuk, A. M., van Oostenbrugge, R. J., Brown, S. B., Campbell, B., White, P., Hill, M. D., Saver, J. L., Weimar, C., Jahan, R., Guillemin, F., ... HERMES Trialists Collaboration (2023). Risk factors of unexplained early neurological deterioration after treatment for ischemic stroke due to large vessel occlusion: a post hoc analysis of the HERMES study. Journal of Neurointerventional Surgery, 15(3), 221-226. https://doi.org/10.1136/neurintsurg-2021-018214
    • Schellekens, M. M. I., Boot, E. M., Verhoeven, J. I., Ekker, M. S., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., de Kort, P. L. M., de Laat, K. F., van Norden, A., Vermeer, S. E., van Zagten, M. S. G., van Oostenbrugge, R. J., Wermer, M. J., Nederkoorn, P. J., ... Tuladhar, A. M. (2023). Subacute cognitive impairment after first-ever transient ischemic attack or ischemic stroke in young adults: The ODYSSEY study. European Stroke Journal, 8(1), 283-293. https://doi.org/10.1177/23969873221132032
    • Kopczak, A., Stringer, M. S., van den Brink, H., Kerkhofs, D., Blair, G. W., van Dinther, M., Onkenhout, L., Wartolowska, K. A., Thrippleton, M. J., Duering, M., Staals, J., Middeke, M., Andre, E., Norrving, B., Bousser, M. G., Mansmann, U., Rothwell, P. M., Doubal, F. N., van Oostenbrugge, R., ... SVDs@Target Investigators (2023). The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial. European Stroke Journal, 8(1), 387-397. https://doi.org/10.1177/23969873221143570
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