• 2016
    • Daeichin, V., Kooiman, K., Skachkov, I., Bosch, J. G., Theelen, T. L., Steiger, K., Needles, A., Janssen, B. J., Daemen, M. J. A. P., van der Steen, A. F. W., de Jong, N., & Sluimer, J. C. (2016). QUANTIFICATION OF ENDOTHELIAL alpha(V)beta(3) EXPRESSION WITH HIGH-FREQUENCY ULTRASOUND AND TARGETED MICROBUBBLES: IN VITRO AND IN VIVO STUDIES. Ultrasound in Medicine and Biology, 42(9), 2283-2293. https://doi.org/10.1016/j.ultrasmedbio.2016.05.005
    • Al-Ali, F., Berkhemer, O. A., Yousman, W. P., Elias, J. J., Bender, E. N., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Dillon, W. P., & Majoie, C. B. L. M. (2016). The Capillary Index Score as a Marker of Viable Cerebral Tissue: Proof of Concept-The Capillary Index Score in the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Trial. Stroke, 47(9), 2286-2291. https://doi.org/10.1161/STROKEAHA.116.013513
    • Gamrekelashvili, J., Giagnorio, R., Jussofie, J., Soehnlein, O., Duchene, J., Briseno, C. G., Ramasamy, S. K., Krishnasamy, K., Limbourg, A., Kapanadze, T., Ishifune, C., Hinkel, R., Radtke, F., Strobl, L. J., Zimber-Strobl, U., Napp, L. C., Bauersachs, J., Haller, H., Yasutomo, K., ... Limbourg, F. P. (2016). Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nature Communications, 7, Article 12597. https://doi.org/10.1038/ncomms12597
    • Lindeboom, L., de Graaf, R. A., Nabuurs, C. I., van Ewijk, E., Hesselink, M. K. C., Wildberger, J. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2016). Quantum coherence spectroscopy to measure dietary fat retention in the liver. JCI INSIGHT, 1(13), Article e84671. https://doi.org/10.1172/jci.insight.84671
    • Berkhemer, O. A., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Yoo, A. J., Lingsma, H. F., Schonewille, W. J., van den Berg, R., Wermer, M. J. H., Boiten, J., Nijeholt, G. J. L., Nederkoorn, P. J., Hollmann, M. W., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., & Roos, Y. B. W. E. M. (2016). The effect of anesthetic management during intra-arterial therapy for acute stroke in MR CLEAN. Neurology, 87(7), 656-664. https://doi.org/10.1212/WNL.0000000000002976
    • Zhu, X., Dahlmans, V., Thali, R., Preisinger, C., Viollet, B., Voncken, J. W., & Neumann, D. (2016). AMP-activated Protein Kinase Up-regulates Mitogen-activated Protein (MAP) Kinase-interacting Serine/Threonine Kinase 1a-dependent Phosphorylation of Eukaryotic Translation Initiation Factor 4E. Journal of Biological Chemistry, 291(33), 17020-17027. https://doi.org/10.1074/jbc.C116.740498
    • van Overbeek, E. C., Staals, J., & van Oostenbrugge, R. J. (2016). Decreased kidney function relates to progression of cerebral microbleeds in lacunar stroke patients. International journal of stroke, 11(6), 695-700. https://doi.org/10.1177/1747493016641966
    • van Bussel, F. C. G., Backes, W. H., van Veenendaal, T. M., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Sep, S. J. S., Dagnelie, P. C., Schaper, N., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. (2016). Functional brain networks are altered in type 2 diabetes and pre-diabetes signs for compensation of cognitive decrements? - The Maastricht Study: signs for compensation of cognitive decrements? - The Maastricht Study. Diabetes, 65(8), 2404-2413. https://doi.org/10.2337/db16-0128
    • Holtackers, R. J., Spronck, B., Heusinkveld, M. H. G., Crombag, G., op het Roodt, J., Delhaas, T., Kooi, E., Reesink, K. D., & Hermeling, E. (2016). Head orientation should be considered in ultrasound studies on carotid artery distensibility. Journal of Hypertension, 34(8), 1551-1555. https://doi.org/10.1097/HJH.0000000000000985
    • Kok, M., Turek, J., Mihl, C., Reinartz, S. D., Gohmann, R. F., Nijssen, E. C., Kats, S., van Ommen, V. G. V. A., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Low contrast media volume in pre-TAVI CT examinations. European Radiology, 26(8), 2426-2435. https://doi.org/10.1007/s00330-015-4080-x
    • De Guio, F., Jouvent, E., Biessels, G. J., Black, S. E., Brayne, C., Chen, C., Cordonnier, C., De Leeuw, F.-E., Dichgans, M., Doubal, F., Duering, M., Dufouil, C., Duzel, E., Fazekas, F., Hachinski, V., Ikram, M. A., Linn, J., Matthews, P. M., Mazoyer, B., ... Chabriat, H. (2016). Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 36(8), 1319-1337. https://doi.org/10.1177/0271678X16647396
    • Schloss, M. J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O., & Steffens, S. (2016). The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Molecular Medicine, 8(8), 937-948. https://doi.org/10.15252/emmm.201506083
    • Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., & Dippel, D. W. J. (2016). Treatment in patients who are not eligible for intravenous alteplase: MR CLEAN subgroup analysis. International journal of stroke, 11(6), 637-645. https://doi.org/10.1177/1747493016641969
    • Klinkenberg, L. J. J., Luyten, P., van der Linden, N., Urgel, K., Snijders, D. P. C., Knackstedt, C., Dennert, R., Kietselaer, B. L. J. H., Mingels, A., Cardinaels, E. P. M., Peeters, F. E. C. M., van Suijlen, J. D. E., ten Kate, J., Marsch, E., Theelen, T. L., Sluimer, J. C., Wouters, K., Bekers, O., Bekkers, B., ... Meex, S. J. R. (2016). Cardiac Troponin T and I Release After a 30-km Run. American Journal of Cardiology, 118(2), 281-287. https://doi.org/10.1016/j.amjcard.2016.04.030
    • Smulders, M. W., Kietselaer, B. L. J. H., Schalla, S., Bucerius, J., Jaarsma, C., van Dieijen-Visser, M. P., Mingels, A. M. A., Brunner-La Rocca, H., Post, M., Das, M., Crijns, H. J. G. M., Wildberger, J. E., & Bekkers, B. (2016). Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging?American Heart Journal, 177, 102-111. https://doi.org/10.1016/j.ahj.2016.03.025
    • Wilde, B., Mertens, A., Arends, S. J., Rouhl, R. P., Bijleveld, R., Huitema, J., Timmermans, S. A., Damoiseaux, J., Witzke, O., Duijvestijn, A. M., van Paassen, P., van Oostenbrugge, R. J., & Tervaert, J. W. C. (2016). Endothelial progenitor cells are differentially impaired in ANCA-associated vasculitis compared to healthy controls. Arthritis Research & Therapy, 18, Article 147. https://doi.org/10.1186/s13075-016-1044-8
    • Skarpengland, T., Holm, S., Scheffler, K., Gregersen, I., Dahl, T. B., Suganthan, R., Segers, F. M., Ostlie, I., Otten, J. J. T., Luna, L., Ketelhuth, D. F. J., Lundberg, A. M., Neurauter, C. G., Hildrestrand, G., Skjelland, M., Bjorndal, B., Svardal, A. M., Iversen, P. O., Hedin, U., ... Aukrust, P. (2016). Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Scientific Reports, 6, Article 28337. https://doi.org/10.1038/srep28337
    • Das, M., & Wildberger, J. E. (2016). Diagnostik der akuten Lungenembolie. Der Radiologe, 56(6), 543-554. https://doi.org/10.1007/s00117-016-0100-3
    • van Hoof, R. H. M., Heeneman, S., Wildberger, J. E., & Kooi, E. (2016). Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature. Current Atherosclerosis Reports, 18(6), Article 33. https://doi.org/10.1007/s11883-016-0583-4
    • Yoo, A. J., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Beumer, D., Lingsma, H. F., Schonewille, W. J., Sprengers, M. E. S., van den Berg, R., van Walderveen, M. A. A., Beenen, L. F. M., Wermer, M. J. H., Nijeholt, G. J. L. A., Boiten, J., Jenniskens, S. F. M., Bot, J. C. J., Boers, A. M. M., Marquering, H. A., Roos, Y. B. W. E. M., ... Majoie, C. B. L. M. (2016). Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN). Lancet Neurology, 15(7), 685-694. https://doi.org/10.1016/S1474-4422(16)00124-1
    • Nabben, M., & Neumann, D. (2016). GSK-3 Inhibitors: Anti-Diabetic Treatment Associated with Cardiac Risk?Cardiovascular Drugs and Therapy, 30(3), 233-235. https://doi.org/10.1007/s10557-016-6669-y
    • Kok, M., Mihl, C., Hendriks, B. M. F., Altintas, S., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Optimizing contrast media application in coronary CT angiography at lower tube voltage: Evaluation in a circulation phantom and sixty patients. European Journal of Radiology, 85(6), 1068-1074. https://doi.org/10.1016/j.ejrad.2016.03.022
    • Post, M. C., Van Dijk, A. P., Hoendermis, E. S., Bogaard, H. J., Van Empel, V., & Boomars, K. A. (2016). PulmoCor: national registry for pulmonary hypertension. Netherlands Heart Journal, 24(6), 425-426. https://doi.org/10.1007/s12471-016-0830-x
    • Klooster, D. C. W., de Louw, A. J. A., Aldenkamp, A. P., Besseling, R. M. H., Mestrom, R. M. C., Carrette, S., Zinger, S., Bergmans, J. W. M., Mess, W. H., Vonck, K., Carrette, E., Breuer, L. E. M., Bernas, A., Tijhuis, A. G., & Boon, P. (2016). Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols. Neuroscience and Biobehavioral Reviews, 65, 113-141. https://doi.org/10.1016/j.neubiorev.2016.02.016
    • Crijnen, Y. S., Nouwens, F., de Lau, L. M. L., Visch-Brink, E. G., van de Sandt-Koenderman, M. W. M. E., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., & Dippel, D. W. J. (2016). Early effect of intra-arterial treatment in ischemic stroke on aphasia recovery in MR CLEAN. Neurology, 86(22), 2049-2055. https://doi.org/10.1212/WNL.0000000000002724
    • Simsekyilmaz, S., Liehn, E. A., Weinandy, S., Schreiber, F., Megens, R. T. A., Theelen, W., Smeets, R., Jockenhoevel, S., Gries, T., Moeller, M., Klee, D., Weber, C., & Zernecke, A. (2016). Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice. PLOS ONE, 11(5), Article e0155829. https://doi.org/10.1371/journal.pone.0155829
    • Bouwmans, A. E. P., Weber, W. E. J., Leentjens, A. F. G., & Mess, W. H. (2016). Transcranial sonography findings related to depression in parkinsonian disorders: cross-sectional study in 126 patients. PEERJ, 4, Article e2037. https://doi.org/10.7717/peerj.2037
    • Beumer, D., Rozeman, A. D., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Algra, A., Boiten, J., Schonewille, W., van Oostenbrugge, R. J., Dippel, D. W. J., & van Zwam, W. H. (2016). The effect of age on outcome after intraarterial treatment in acute ischemic stroke: a MR CLEAN pretrial study. BMC Neurology, 16, Article 68. https://doi.org/10.1186/s12883-016-0592-5
    • Wichapong, K., Alard, J. .-E., Ortega-Gomez, A., Weber, C., Hackeng, T. M., Soehnlein, O., & Nicolaes, G. A. F. (2016). Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1). Journal of Medicinal Chemistry, 59(9), 4289-4301. https://doi.org/10.1021/acs.jmedchem.5b01952
    • Douven, E., Schievink, S. H. J., Verhey, F. R. J., van Oostenbrugge, R. J., Aalten, P., Staals, J., & Köhler, S. (2016). The Cognition and Affect after Stroke - a Prospective Evaluation of Risks (CASPER) study: rationale and design. BMC Neurology, 16, Article 65. https://doi.org/10.1186/s12883-016-0588-1
    • Koppen, H., Palm-Meinders, I. H., Mess, W. H., Keunen, R. W., Terwindt, G. M., Launer, L. J., van Buchem, M. A., Kruit, M. C., & Ferrari, M. D. (2016). Systemic right-to-left shunts, ischemic brain lesions, and persistent migraine activity. Neurology, 86(18), 1668-1675. https://doi.org/10.1212/WNL.0000000000002538
    • Haasdijk, R. A., Den Dekker, W. K., Cheng, C., Tempel, D., Szulcek, R., Bos, F. L., Hermkens, D. M. A., Chrifi, I., Brandt, M. M., Van Dijk, C., Xu, Y. J., Van De Kamp, E. H. M., Blonden, L. A. J., Van Bezu, J., Sluimer, J. C., Biessen, E. A. L., Amerongen, G. P. V. N., & Duckers, H. J. (2016). THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE(-/-) mice. Cardiovascular Research, 110(1), 129-139. https://doi.org/10.1093/cvr/cvw015
    • Yan, I., Schwarz, J., Luecke, K., Schumacher, N., Schumacher, V., Schmidt, S., Rabe, B., Saftig, P., Donners, M., Rose-John, S., Mittruecker, H.-W., & Chalaris, A. (2016). ADAM17 controls IL-6 signaling by cleavage of the murine IL-6R alpha from the cell surface of leukocytes during inflammatory responses. Journal of Leukocyte Biology, 99(5), 749-760. https://doi.org/10.1189/jlb.3A0515-207R
    • Vainer, J., Habets, J. H. M., Schalla, S., Lousberg, A. H. P., de Pont, C. D. J. M., Vöö, S., Brans, B. T., Hoorntje, J. C. A., & Waltenberger, J. (2016). Cardiac shockwave therapy in patients with chronic refractory angina pectoris. Netherlands Heart Journal, 24(5), 343-349. https://doi.org/10.1007/s12471-016-0821-y
    • Breuer, L. E. M., Boon, P., Bergmans, J. W. M., Mess, W. H., Besseling, R. M. H., de Louw, A., Tijhuis, A. G., Zinger, S., Bernas, A., Klooster, D. C. W., & Aldenkamp, A. P. (2016). Cognitive deterioration in adult epilepsy: Does accelerated cognitive ageing exist?Neuroscience and Biobehavioral Reviews, 64, 1-11. https://doi.org/10.1016/j.neubiorev.2016.02.004
    • Gemmink, A., Bosma, M., Kuijpers, H. J. H., Hoeks, J., Schaart, G., van Zandvoort, M., Schrauwen, P., & Hesselink, M. K. C. (2016). Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia, 59(5), 1040–1048. https://doi.org/10.1007/s00125-016-3865-z
    • Vöö, S., Kwee, R. M., Sluimer, J. C., Schreuder, F. H. B. M., Wierts, R., Bauwens, M., Heeneman, S., Cleutjens, J. P. M., van Oostenbrugge, R. J., Daemen, J.-W. H., Daemen, M. J. A. P., Mottaghy, F. M., & Kooi, E. (2016). Imaging Intraplaque Inflammation in Carotid Atherosclerosis With F-18-Fluorocholine Positron Emission Tomography-Computed Tomography Prospective Study on Vulnerable Atheroma With Immunohistochemical Validation. Circulation-Cardiovascular Imaging, 9(5), Article e004467. https://doi.org/10.1161/CIRCIMAGING.115.004467
    • Weber, C., Doering, Y., & Noels, H. (2016). Potential cell-specific functions of CXCR4 in atherosclerosis. Hämostaseologie, 36(2), 97-102. https://doi.org/10.5482/HAMO-14-10-0054
    • Goyal, M., Menon, B. K., van Zwam, W. H., Dippel, D. W. J., Mitchell, P. J., Demchuk, A. M., Davalos, A., Majoie, C. B. L. M., van der Lugt, A., de Miquel, M. A., Donnan, G. R. A., Roos, Y. B. W. E. M., Bonafe, A., Jahan, R., Diener, H.-C., van den Berg, L. A., Levy, E. I., Berkhemer, O. A., Pereira, V. M., ... Jovin, T. G. (2016). Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet, 387(10029), 1723-1731. https://doi.org/10.1016/S0140-6736(16)00163-X
    • Cardinaels, E. P. M., Altintas, S., Versteylen, M. O., Joosen, I. A., Jellema, L.-J. C., Wildberger, J. E., Das, M., Crijns, H. J., Bekers, O., van Dieijen-Visser, M. P., Kietselaer, B. L., & Mingels, A. M. A. (2016). High-Sensitivity Cardiac Troponin Concentrations in Patients with Chest Discomfort: Is It the Heart or the Kidneys As Well?PLOS ONE, 11(4), Article e0153300. https://doi.org/10.1371/journal.pone.0153300
    • Miglianico, M., Nicolaes, G. A. F., & Neumann, D. (2016). Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design. Journal of Medicinal Chemistry, 59(7), 2879-2893. https://doi.org/10.1021/acs.jmedchem.5b01201
    • Oligschläger, Y., Miglianico, M., Dahlmans, V. E., Rubio-Villena, C., Chanda, D., Adelaida Garcia-Gimeno, M., Coumans, W. A., Liu, Y., Voncken, J. W., Luiken, J. J. F. P., Glatz, J. F. C., Sanz, P., & Neumann, D. (2016). The interaction between AMPK beta 2 and the PP1-targeting subunit R6 is dynamically regulated by intracellular glycogen content. Biochemical Journal, 473(7), 937-947. https://doi.org/10.1042/BJ20151035
    • Spronck, B., Megens, R. T. A., Reesink, K. D., & Delhaas, T. (2016). A method for three-dimensional quantification of vascular smooth muscle orientation: application in viable murine carotid arteries. Biomechanics and modeling in mechanobiology, 15(2), 419-432. https://doi.org/10.1007/s10237-015-0699-4
    • Frusch, K. J. M., Houben, R., Schreuder, F. H. B. M., Postma - Jacobi, L., & Staals, J. (2016). Association between eye position on brain scan and hospital mortality in acute intracerebral hemorrhage. European Journal of Neurology, 23(4), 831-835. https://doi.org/10.1111/ene.12951
    • Maessen, D. E., Brouwers, O., Gaens, K. H., Wouters, K., Cleutjens, J. P., Janssen, B. J., Miyata, T., Stehouwer, C. D., & Schalkwijk, C. G. (2016). Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. Diabetes, 65(4), 956-966. https://doi.org/10.2337/db15-1390
    • Kemerink, G. J., van Engelshoven, J., Simon, K. J., Kutterer, G., & Wildberger, J. E. (2016). Early X-ray workers: an effort to assess their numbers, risk, and most common (skin) affliction. Insights into Imaging, 7(2), 275-282. https://doi.org/10.1007/s13244-015-0457-2
    • Uiterwijk, R., Huijts, M., Staals, J., Rouhl, R. P. W., De Leeuw, P. W., Kroon, A. A., & Van Oostenbrugge, R. J. (2016). Endothelial Activation Is Associated With Cognitive Performance in Patients With Hypertension. American Journal of Hypertension, 29(4), 464-469. https://doi.org/10.1093/ajh/hpv122
    • Mihl, C., Kok, M., Altintas, S., Kietselaer, B. L. J. H., Turek, J., Wildberger, J. E., & Das, M. (2016). Evaluation of individually body weight adapted contrast media injection in coronary CT-angiography. European Journal of Radiology, 85(4), 830-836. https://doi.org/10.1016/j.ejrad.2015.12.031
    • Kok, M., de Haan, M., Mihl, C., Eijsvoogel, N. G., Hendriks, B. M. F., Sailer, A. M., Derks, K., Schnerr, R. S., Schurink, G., Wildberger, J. E., & Das, M. (2016). Individualized CT Angiography Protocols for the Evaluation of the Aorta: A Feasibility Study. Journal of Vascular and Interventional Radiology, 27(4), 531-538. https://doi.org/10.1016/j.jvir.2016.01.009
    • Mahl, C., Egea, V., Megens, R. T. A., Pitsch, T., Santovito, D., Weber, C., & Ries, C. (2016). RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/beta-catenin signaling in human mesenchymal stem cells. Cellular and Molecular Life Sciences, 73(7), 1489-1501. https://doi.org/10.1007/s00018-015-2054-4