• 2018
    • Ho, P.-Y., Li, H., Pavlov, T. S., Tuerk, R. D., Tabares, D., Brunisholz, R., Neumann, D., Staruschenko, A., & Hallows, K. R. (2018). β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells. Journal of Biological Chemistry, 293(29), 11612-11624. https://doi.org/10.1074/jbc.RA118.003082
    • Mulder, M. J. H. L., Jansen, I. G. H., Goldhoorn, R.-J. B., Venema, E., Chalos, V., Compagne, K. C. J., Roozenbeek, B., Lingsma, H. F., Schonewille, W. J., van den Wijngaard, I. R., Boiten, J., Vos, J. A., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Registry Investigators (2018). Time to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results. Circulation, 138(3), 232-240. https://doi.org/10.1161/CIRCULATIONAHA.117.032600
    • Autar, A. S. A., Hund, H. M., Ramlal, S. A., Hansen, D., Nijeholt, G. J. L. A., Emmer, B. J., de Maat, M. P. M., Dippel, D. W. J., van der Lugt, A., van Es, A. C. G. M., van Beusekom, H. M. M., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Staals, J., Postma - Jacobi, L., van Oostenbrugge, R. J., & van Zwam, W. (2018). High-Resolution Imaging of Interaction Between Thrombus and Stent-Retriever in Patients With Acute Ischemic Stroke. Journal of the American Heart Association, 7(13), Article 008563. https://doi.org/10.1161/JAHA.118.008563
    • van der Vorst, E. P. C., Weber, C., & Donners, M. M. P. C. (2018). A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches. Thrombosis and Haemostasis, 118(7), 1167-1175. https://doi.org/10.1055/s-0038-1660479
    • Loos, C. M. J., Staals, J., & Wardlaw, J. M. (2018). Response by Loos et al to Letter Regarding Article, "Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging". Stroke, 49(7), E269-E269. https://doi.org/10.1161/STROKEAHA.118.021876
    • Loos, C. M. J., McHutchison, C., Cvoro, V., Makin, S. D. J., Staals, J., Chappell, F., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke. International journal of stroke, 13(5), 518-524. https://doi.org/10.1177/1747493017730780
    • Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2018). Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice. Gut, 67(7), 1317-1327. https://doi.org/10.1136/gutjnl-2016-313654
    • Horehledova, B., Mihl, C., Schwemmer, C., Hendriks, B. M. F., Eijsvoogel, N. G., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2018). Aortic root evaluation prior to transcatheter aortic valve implantation-Correlation of manual and semi-automatic measurements. PLOS ONE, 13(6), Article e0199732. https://doi.org/10.1371/journal.pone.0199732
    • Eersels, K., Diliën, H., Lowdon, J., Steen Redeker, E., Rogosic, R., Heidt, B., Peeters, M., Cornelis, P., Lux, P., Reutelingsperger, C., Schurgers, L., Cleij, T., & van Grinsven, B. (2018). A Novel Biomimetic Tool for Assessing Vitamin K Status Based on Molecularly Imprinted Polymers. Nutrients, 10(6), Article 751. https://doi.org/10.3390/nu10060751
    • Haeren, R. H. L., Rijkers, K., Schijns, O. E. M. G., Dings, J., Hoogland, G., van Zandvoort, M. A. M. J., Vink, H., & van Overbeeke, J. J. (2018). In vivo assessment of the human cerebral microcirculation and its glycocalyx: A technical report. Journal of Neuroscience Methods, 303, 114-125. https://doi.org/10.1016/j.jneumeth.2018.03.009
    • Makin, S. D. J., Doubal, F. N., Shuler, K., Chappell, F. M., Staals, J., Dennis, M. S., & Wardlaw, J. M. (2018). The impact of early-life intelligence quotient on post stroke cognitive impairment. European Stroke Journal, 3(2), 145-156. https://doi.org/10.1177/2396987317750517
    • Boers, A. M. M., Sales Barros, R., Jansen, I. G. H., Berkhemer, O. A., Beenen, L. F. M., Menon, B. K., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Slump, C. H., Majoie, C. B. L. M., & Marquering, H. A. (2018). Value of Quantitative Collateral Scoring on CT Angiography in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 39(6), 1074-1082. https://doi.org/10.3174/ajnr.A5623
    • Dudink, E. A. M. P., Peeters, F. E. C. M., Altintas, S., Heckman, L. I. B., Haest, R. J., Kragten, H., Kietselaer, B. L. J. H., Wildberger, J., Luermans, J. G. L. M., Weijs, B., & Crijns, H. J. G. M. (2018). Agatston score of the descending aorta is independently associated with coronary events in a low-risk population. Open Heart, 5(2), Article 000893. https://doi.org/10.1136/openhrt-2018-000893
    • Chennupati, R., Meens, M. J., Janssen, B. J., van Dijk, P., Hakvoort, T. B. M., Lamers, W. H., De Mey, J. G. R., & Koehler, S. E. (2018). Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice. Physiological Reports, 6(11), Article 13717. https://doi.org/10.14814/phy2.13717
    • Schut, S., Driessen, E., van Tartwijk, J., van der Vleuten, C., & Heeneman, S. (2018). Stakes in the eye of the beholder: an international study of learners' perceptions within programmatic assessment. Medical Education, 52(6), 654-663. https://doi.org/10.1111/medu.13532
    • Bindels, E., Verberg, C., Scherpbier, A., Heeneman, S., & Lombarts, K. (2018). Reflection revisited: how physicians conceptualize and experience reflection in professional practice – a qualitative study. BMC Medical Education, 18(1), Article 105. https://doi.org/10.1186/s12909-018-1218-y
    • Kappelhof, M., Marquering, H. A., Berkhemer, O. A., Borst, J., van der Lugt, A., van Zwam, W. H., Vos, J. A., Nijeholt, G. L. A., Majoie, C. B. L. M., & Emmer, B. J. (2018). Accuracy of CT Angiography for Differentiating Pseudo-Occlusion from True Occlusion or High-Grade Stenosis of the Extracranial ICA in Acute Ischemic Stroke: A Retrospective MR CLEAN Substudy. American Journal of Neuroradiology, 39(5), 892-898. https://doi.org/10.3174/ajnr.A5601
    • Geraets, I. M. E., Chanda, D., van Tienen, F. H. J., van den Wijngaard, A., Kamps, R., Neumann, D., Liu, Y., Glatz, J. F. C., Luiken, J. J. F. P., & Nabben, M. (2018). Human embryonic stem cell-derived cardiomyocytes as an in vitro model to study cardiac insulin resistance. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1864(5), 1960-1967. https://doi.org/10.1016/j.bbadis.2017.12.025
    • Boere, H., Eijsvoogel, N. G., Sailer, A. M., Wildberger, J. E., de Haan, M. W., Das, M., & Jeukens, C. R. L. P. N. (2018). Implementation of Size-Dependent Local Diagnostic Reference Levels for CT Angiography. American Journal of Roentgenology, 210(5), W226-W233. https://doi.org/10.2214/AJR.17.18566
    • Loos, C. M. J., Makin, S. D. J., Staals, J., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging. Stroke, 49(5), 1183–1188. https://doi.org/10.1161/STROKEAHA.117.020495
    • Hendriks, B. M. F., Eijsvoogel, N. G., Kok, M., Martens, B., Wildberger, J. E., & Das, M. (2018). Optimizing Pulmonary Embolism Computed Tomography in the Age of Individualized Medicine A Prospective Clinical Study. Investigative Radiology, 53(5), 306-312. https://doi.org/10.1097/RLI.0000000000000443
    • Steinbuch, J., Schreuder, F. H. B. M., Reesink, K. D., Hoeks, A. P. G., & Mess, W. H. (2018). ORTHOGONAL B-MODE EVALUATION OF COMMON CAROTID ARTERY PLAQUES REVEALS THE ABSENCE OF OUTWARD REMODELING. Ultrasound in Medicine and Biology, 44(5), 986-994. https://doi.org/10.1016/j.ultrasmedbio.2017.12.013
    • Bisha, M., Dao, T.-V., Gholamreza-Fahimi, E., Vogt, M., van Zandvoort, M., Weber, S., Bas, M., Khosravani, F., Kojda, G., & Suvorava, T. (2018). The role of bradykinin receptor type 2 in spontaneous extravasation in mice skin: implications for non-allergic angio-oedema. British Journal of Pharmacology, 175(10), 1607-1620. https://doi.org/10.1111/bph.14166
    • Sedding, D. G., Boyle, E. C., Demandt, J. A. F., Sluimer, J. C., Dutzmann, J., Haverich, A., & Bauersachs, J. (2018). Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease. Frontiers in Immunology, 9(APR), Article 706. https://doi.org/10.3389/fimmu.2018.00706
    • Kimberly, W. T., Dutra, B. G., Boers, A. M. M., Alves, H. C. B. R., Berkhemer, O. A., van den Berg, L., Sheth, K. N., Roos, Y. B. W. E. M., van der Lugt, A., Beenen, L. F. M., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Marquering, H., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). Association of Reperfusion With Brain Edema in Patients With Acute Ischemic Stroke A Secondary Analysis of the MR CLEAN Trial. JAMA Neurology, 75(4), 453-461. https://doi.org/10.1001/jamaneurol.2017.5162
    • Peeters, F. E. C. M., van Mourik, M. J. W., Meex, S. J. R., Bucerius, J., Schalla, S. M., Gerretsen, S. C., Mihl, C., Dweck, M. R., Schurgers, L. J., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using F-18-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients, 10(4), Article 386. https://doi.org/10.3390/nu10040386
    • Dijkland, S. A., Voormolen, D. C., Venema, E., Roozenbeek, B., Polinder, S., Haagsma, J. A., Nieboer, D., Chalos, V., Yoo, A. J., Schreuders, J., van der Lugt, A., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Zwam, W. H., van Oostenbrugge, R. J., Steyerberg, E. W., Dippel, D. W. J., Lingsma, H. F., & MR CLEAN Investigators (2018). Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials A Simulation Study. Stroke, 49(4), 965-971. https://doi.org/10.1161/STROKEAHA.117.020194
    • Leunissen, T., van Vriesland, D., den Ruijter, H., Moll, F., Mess, W., & de Borst, G. J. (2018). Validation of the Automated Electronic Microemboli Detection System in Patients Undergoing Carotid Endarterectomy. Ultraschall in der Medizin (Stuttgart, Germany : 1980), 39(2), 198-205. https://doi.org/10.1055/s-0043-106737
    • Jansen, I. G. H., Mulder, M. J. H. L., Goldhoorn, R.-J. B., Emmer, B. J., van Es, A. C. G. M., Roozenbeek, B., Schonewille, W. J., van den Berg, R., Coutinho, J. M., Staals, J., Postma, A. A., Lycklama, G. J., Hofmeijer, J., Martens, J. M., den Hertog, H. M., Sturm, F. J. C., van der Worp, H. B., Lo, R. H., Heijboer, R. J. J., ... MR CLEAN Registry Investigators (2018). Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry). BMJ, 360, Article 949. https://doi.org/10.1136/bmj.k949
    • Verdonschot, J. A. J., Hazebroek, M. R., Derks, K. W. J., Aizpurua, A. B., Merken, J. J., Wang, P., Bierau, J., van den Wijngaard, A., Schalla, S. M., Hamid, M. A. A., van Bilsen, M., van Empel, V. P. M., Knackstedt, C., Brunner-La Rocca, H.-P., Brunner, H. G., Krapels, I. P. C., & Heymans, S. R. B. (2018). Titin cardiomyopathy leads to altered mitochondrial energetics, increased fibrosis and long-termlife-threatening arrhythmias. European Heart Journal, 39(10), 864-873. https://doi.org/10.1093/eurheartj/ehx808
    • Douven, E., Kohler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. R. J., & Aalten, P. (2018). Baseline Vascular Cognitive Impairment Predicts the Course of Apathetic Symptoms After Stroke: The CASPER Study. American Journal of Geriatric Psychiatry, 26(3), 291-300. https://doi.org/10.1016/j.jagp.2017.09.022
    • Wetzels, S., Bijnen, M., Wijnands, E., Biessen, E. A. L., Schalkwijk, C. G., & Wouters, K. (2018). Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry. Journal of visualized experiment, (133), Article e57319 . https://doi.org/10.3791/57319
    • Maracle, C. X., Agca, R., Helder, B., Meeuwsen, J. A. L., Niessen, H. W. M., Biessen, E. A. L., de Winther, M. P. J., de Jager, S. C. A., Nurmohamed, M. T., & Tas, S. W. (2018). Noncanonical NF-kappa B signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction. Atherosclerosis, 270, 33-41. https://doi.org/10.1016/j.atherosclerosis.2018.01.032
    • Gombert, A., Grommes, J., Hilkman, D., Kotelis, D., Mess, W. H., & Jacobs, M. J. (2018). Recovery of lost motor evoked potentials in open thoracoabdominal aortic aneurysm repair using intercostal artery bypass. Journal of Vascular Surgery Cases and Innovative Techniques, 4(1), 54-57. https://doi.org/10.1016/j.jvscit.2017.12.004
    • Thomassen, S., Mastenbroek, T. G., Swieringa, F., Winckers, K., Feijge, M. A. H., Schrijver, R., Cosemans, J. M. E. M., Maroney, S. A., Mast, A. E., Hackeng, T. M., & Heemskerk, J. W. M. (2018). Suppressive Role of Tissue Factor Pathway Inhibitor-alpha in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength. Thrombosis and Haemostasis, 118(3), 502-513. https://doi.org/10.1055/s-0038-1627453
    • Houben, R., Schreuder, F. H. B. M., Bekelaar, K. J., Claessens, D., van Oostenbrugge, R. J., & Staals, J. (2018). Predicting Prognosis of Intracerebral Hemorrhage (ICH): Performance of ICH Score Is Not Improved by Adding Oral Anticoagulant Use. Frontiers in Neurology, 9(FEB), Article 100. https://doi.org/10.3389/fneur.2018.00100
    • Nagy, M., Mastenbroek, T. G., Mattheij, N. J. A., de Witt, S., Clemetson, K. J., Kirschner, J., Schulz, A. S., Vraetz, T., Speckmann, C., Braun, A., Cosemans, J. M. E. M., Zieger, B., & Heemskerk, J. W. M. (2018). Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies. Haematologica-the Hematology Journal, 103(3), 540-549. https://doi.org/10.3324/haematol.2017.176974
    • Jansen, I. G. H., van Vuuren, A. B., van Zwam, W. H., van den Wijngaard, I. R., Berkhemer, O. A., Lingsma, H. F., Slump, C. H., van Oostenbrugge, R. J., Treurniet, K. M., Dippel, D. W. J., van Walderveen, M. A. A., van der Lugt, A., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., van den Berg, R., & MR CLEAN Trial Investigators (2018). Absence of Cortical Vein Opacification Is Associated with Lack of Intra-arterial Therapy Benefit in Stroke. Radiology, 286(2), 643-650. https://doi.org/10.1148/radiol.2017162445
    • van Nijnatten, T. J. A., Goorts, B., Voo, S., de Boer, M., Kooreman, L. F. S., Heuts, E. M., Wildberger, J. E., Mottaghy, F. M., Lobbes, M. B. I., & Smidt, M. L. (2018). Added value of dedicated axillary hybrid 18F-FDG PET/MRI for improved axillary nodal staging in clinically node-positive breast cancer patients: a feasibility study. European Journal of Nuclear Medicine and Molecular Imaging, 45(2), 179-186. https://doi.org/10.1007/s00259-017-3823-0
    • Treurniet, K. M., Berkhemer, O. A., Immink, R. V., Lingsma, H. F., Ward-van der Stam, V. M. C., Hollmann, M. W., Vuyk, J., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Dippel, D. W. J., Coutinho, J. M., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). A decrease in blood pressure is associated with unfavorable outcome in patients undergoing thrombectomy under general anesthesia. Journal of Neurointerventional Surgery, 10(2), 107-111. https://doi.org/10.1136/neurintsurg-2017-012988
    • Alves, H. C., Treurniet, K. M., Dutra, B. G., Jansen, I. G. H., Boers, A. M. M., Santos, E. M. M., Berkhemer, O. A., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Roos, Y. B. W. E. M., Yoo, A. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2018). Associations Between Collateral Status and Thrombus Characteristics and Their Impact in Anterior Circulation Stroke. Stroke, 49(2), 391-396. https://doi.org/10.1161/STROKEAHA.117.019509
    • Cosemans, J. M. E. M. (2018). At the MERcy of platelet primers. Journal of Thrombosis and Haemostasis, 16(2), 349-351. https://doi.org/10.1111/jth.13915
    • Saba, L., Yuan, C., Hatsukami, T. S., Balu, N., Qiao, Y., DeMarco, J. K., Saam, T., Moody, A. R., Li, D., Matouk, C. C., Johnson, M. H., Jager, H. R., Mossa-Basha, M., Kooi, M. E., Fan, Z., Saloner, D., Wintermark, M., Mikulis, D. J., Wasserman, B. A., & Vessel Wall Imaging Study (2018). Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology. American Journal of Neuroradiology, 39(2), E9-E31. https://doi.org/10.3174/ajnr.A5488
    • Henskens, Y. M. C., Gulpen, A. J. W., van Oerle, R., Wetzels, R., Verhezen, P., Spronk, H., Schalla, S., Crijns, H. J., ten Cate, H., & ten Cate-Hoek, A. (2018). Detecting clinically relevant rivaroxaban or dabigatran levels by routine coagulation tests or thromboelastography in a cohort of patients with atrial fibrillation. Thrombosis Journal, 16(1), Article 3. https://doi.org/10.1186/s12959-017-0160-2
    • van Nijnatten, T. J. A., Schipper, R. J., Lobbes, M. B. I., van Roozendaal, L. M., Voo, S., Moossdorff, M., Paiman, M. .-L., de Vries, B., Keymeulen, K. B. M. I., Wildberger, J. E., Smidt, M. L., & Beets-Tan, R. G. H. (2018). Diagnostic performance of gadofosveset-enhanced axillary MRI for nodal (re)staging in breast cancer patients: results of a validation study. Clinical Radiology, 73(2), 168-175. https://doi.org/10.1016/j.crad.2017.09.005
    • Uiterwijk, R., Staals, J., Huijts, M., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2018). Framingham Stroke Risk Profile is related to cerebral small vessel disease progression and lower cognitive performance in patients with hypertension. Journal of Clinical Hypertension, 20(2), 240-245. https://doi.org/10.1111/jch.13175
    • Wong, S. M., Backes, W. H., Zhang, C. E., Staals, J., van Oostenbrugge, R. J., Jeukens, C. R. L. P. N., & Jansen, J. F. A. (2018). On the Reproducibility of Inversion Recovery Intravoxel Incoherent Motion Imaging in Cerebrovascular Disease. American Journal of Neuroradiology, 39(2), 226-231. https://doi.org/10.3174/ajnr.A5474
    • Heusinkveld, M. H. G., Quicken, S., Holtackers, R. J., Huberts, W., Reesink, K. D., Delhaas, T., & Spronck, B. (2018). Uncertainty quantification and sensitivity analysis of an arterial wall mechanics model for evaluation of vascular drug therapies. Biomechanics and modeling in mechanobiology, 17(1), 55-69. https://doi.org/10.1007/s10237-017-0944-0
    • Pacifico, J. L., van der Vleuten, C. P. M., Muijtjens, A. M. M., Sana, E. A., & Heeneman, S. (2018). Cross-validation of a learning climate instrument in a non-western postgraduate clinical environment. BMC Medical Education, 18(1), Article 22. https://doi.org/10.1186/s12909-018-1127-0
    • van der Vorst, E. P. C., de Jong, R. J., & Donners, M. M. P. C. (2018). Message in a Microbottle: Modulation of Vascular Inflammation and Atherosclerosis by Extracellular Vesicles. Frontiers in Cardiovascular Medicine, 5, Article 2. https://doi.org/10.3389/fcvm.2018.00002