• 2018
    • Suthahar, N., Meijers, W. C., Ho, J. E., Gansevoort, R. T., Voors, A. A., van der Meer, P., Bakker, S. J. L., Heymans, S., van Empel, V., Schroen, B., van der Harst, P., van Veldhuisen, D. J., & de Boer, R. A. (2018). Sex-specific associations of obesity and N-terminal pro-B-type natriuretic peptide levels in the general population. European journal of heart failure, 20(8), 1205-1214. https://doi.org/10.1002/ejhf.1209
    • van Tuijl, J. H., van Raak, E. P. M., van Oostenbrugge, R. J., Aldenkamp, A. P., & Rouhl, R. P. W. (2018). The occurrence of seizures after ischemic stroke does not influence long-term mortality; a 26-year follow-up study. Journal of Neurology, 265(8), 1780-1788. https://doi.org/10.1007/s00415-018-8907-7
    • Ho, P.-Y., Li, H., Pavlov, T. S., Tuerk, R. D., Tabares, D., Brunisholz, R., Neumann, D., Staruschenko, A., & Hallows, K. R. (2018). β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells. Journal of Biological Chemistry, 293(29), 11612-11624. https://doi.org/10.1074/jbc.RA118.003082
    • Mulder, M. J. H. L., Jansen, I. G. H., Goldhoorn, R.-J. B., Venema, E., Chalos, V., Compagne, K. C. J., Roozenbeek, B., Lingsma, H. F., Schonewille, W. J., van den Wijngaard, I. R., Boiten, J., Vos, J. A., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Registry Investigators (2018). Time to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results. Circulation, 138(3), 232-240. https://doi.org/10.1161/CIRCULATIONAHA.117.032600
    • Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8(1), Article 10647. https://doi.org/10.1038/s41598-018-29026-0
    • Domschke, G., Linden, F., Pawig, L., Hafner, A., Akhavanpoor, M., Reymann, J., Doesch, A. O., Erbel, C., Weber, C., Katus, H. A., Noels, H., Erfle, H., Gleissner, C. A., & Runz, H. (2018). Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Scientific Reports, 8(1), Article 10516. https://doi.org/10.1038/s41598-018-28790-3
    • Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G. A. F., Weber, C., Viola, J. R., Hidalgo, A., Scheiermann, C., & Soehnlein, O. (2018). Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism, 28(1), 175-182.e5. https://doi.org/10.1016/j.cmet.2018.05.002
    • Autar, A. S. A., Hund, H. M., Ramlal, S. A., Hansen, D., Nijeholt, G. J. L. A., Emmer, B. J., de Maat, M. P. M., Dippel, D. W. J., van der Lugt, A., van Es, A. C. G. M., van Beusekom, H. M. M., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Staals, J., Postma - Jacobi, L., van Oostenbrugge, R. J., & van Zwam, W. (2018). High-Resolution Imaging of Interaction Between Thrombus and Stent-Retriever in Patients With Acute Ischemic Stroke. Journal of the American Heart Association, 7(13), Article 008563. https://doi.org/10.1161/JAHA.118.008563
    • van der Vorst, E. P. C., Weber, C., & Donners, M. M. P. C. (2018). A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches. Thrombosis and Haemostasis, 118(7), 1167-1175. https://doi.org/10.1055/s-0038-1660479
    • Loos, C. M. J., Staals, J., & Wardlaw, J. M. (2018). Response by Loos et al to Letter Regarding Article, "Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging". Stroke, 49(7), E269-E269. https://doi.org/10.1161/STROKEAHA.118.021876
    • Loos, C. M. J., McHutchison, C., Cvoro, V., Makin, S. D. J., Staals, J., Chappell, F., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke. International journal of stroke, 13(5), 518-524. https://doi.org/10.1177/1747493017730780
    • Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2018). Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice. Gut, 67(7), 1317-1327. https://doi.org/10.1136/gutjnl-2016-313654
    • Horehledova, B., Mihl, C., Schwemmer, C., Hendriks, B. M. F., Eijsvoogel, N. G., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2018). Aortic root evaluation prior to transcatheter aortic valve implantation-Correlation of manual and semi-automatic measurements. PLOS ONE, 13(6), Article e0199732. https://doi.org/10.1371/journal.pone.0199732
    • van der Vorst, E. P. C., & Weber, C. (2018). Metabolomic profiling of atherosclerotic plaques: towards improved cardiovascular risk stratification. European Heart Journal, 39(24), 2311-2313. https://doi.org/10.1093/eurheartj/ehy117
    • Busygina, K., Jamasbi, J., Seiler, T., Deckmyn, H., Weber, C., Brandl, R., Lorenz, R., & Siess, W. (2018). Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans. Blood, 131(24), 2605-2616. https://doi.org/10.1182/blood-2017-09-808808
    • Eersels, K., Diliën, H., Lowdon, J., Steen Redeker, E., Rogosic, R., Heidt, B., Peeters, M., Cornelis, P., Lux, P., Reutelingsperger, C., Schurgers, L., Cleij, T., & van Grinsven, B. (2018). A Novel Biomimetic Tool for Assessing Vitamin K Status Based on Molecularly Imprinted Polymers. Nutrients, 10(6), Article 751. https://doi.org/10.3390/nu10060751
    • Tunon, J., Back, M., Badimon, L., Bochaton-Piallat, M.-L., Cariou, B., Daemen, M. J., Egido, J., Evans, P. C., Francis, S. E., Ketelhuth, D. F. J., Lutgens, E., Matter, C. M., Monaco, C., Steffens, S., Stroes, E., Vindis, C., Weber, C., Hoefer, I. E., & ESC Working Grp Atherosclerosis (2018). Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. European Journal of Preventive Cardiology, 25(9), 948-955. https://doi.org/10.1177/2047487318773384
    • Haeren, R. H. L., Rijkers, K., Schijns, O. E. M. G., Dings, J., Hoogland, G., van Zandvoort, M. A. M. J., Vink, H., & van Overbeeke, J. J. (2018). In vivo assessment of the human cerebral microcirculation and its glycocalyx: A technical report. Journal of Neuroscience Methods, 303, 114-125. https://doi.org/10.1016/j.jneumeth.2018.03.009
    • Makin, S. D. J., Doubal, F. N., Shuler, K., Chappell, F. M., Staals, J., Dennis, M. S., & Wardlaw, J. M. (2018). The impact of early-life intelligence quotient on post stroke cognitive impairment. European Stroke Journal, 3(2), 145-156. https://doi.org/10.1177/2396987317750517
    • Barkhuizen, M., van Dijck, F. J. P., Jellema, R. K., Gussenhoven, R., Engelbertink, I., van Mechele, R., Cleutjens, J. P. M., Seehase, M., Steinbusch, H. W. M., Zimmerman, L. J., Gavilanes, A. W. D., & Kramer, B. W. (2018). The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb. Pediatric Research, 83(6), 1190-1199. https://doi.org/10.1038/pr.2018.42
    • Boers, A. M. M., Sales Barros, R., Jansen, I. G. H., Berkhemer, O. A., Beenen, L. F. M., Menon, B. K., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Slump, C. H., Majoie, C. B. L. M., & Marquering, H. A. (2018). Value of Quantitative Collateral Scoring on CT Angiography in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 39(6), 1074-1082. https://doi.org/10.3174/ajnr.A5623
    • Dudink, E. A. M. P., Peeters, F. E. C. M., Altintas, S., Heckman, L. I. B., Haest, R. J., Kragten, H., Kietselaer, B. L. J. H., Wildberger, J., Luermans, J. G. L. M., Weijs, B., & Crijns, H. J. G. M. (2018). Agatston score of the descending aorta is independently associated with coronary events in a low-risk population. Open Heart, 5(2), Article 000893. https://doi.org/10.1136/openhrt-2018-000893
    • Schut, S., Driessen, E., van Tartwijk, J., van der Vleuten, C., & Heeneman, S. (2018). Stakes in the eye of the beholder: an international study of learners' perceptions within programmatic assessment. Medical Education, 52(6), 654-663. https://doi.org/10.1111/medu.13532
    • Bindels, E., Verberg, C., Scherpbier, A., Heeneman, S., & Lombarts, K. (2018). Reflection revisited: how physicians conceptualize and experience reflection in professional practice – a qualitative study. BMC Medical Education, 18(1), Article 105. https://doi.org/10.1186/s12909-018-1218-y
    • Kappelhof, M., Marquering, H. A., Berkhemer, O. A., Borst, J., van der Lugt, A., van Zwam, W. H., Vos, J. A., Nijeholt, G. L. A., Majoie, C. B. L. M., & Emmer, B. J. (2018). Accuracy of CT Angiography for Differentiating Pseudo-Occlusion from True Occlusion or High-Grade Stenosis of the Extracranial ICA in Acute Ischemic Stroke: A Retrospective MR CLEAN Substudy. American Journal of Neuroradiology, 39(5), 892-898. https://doi.org/10.3174/ajnr.A5601
    • Rami, M., Guillamat-Prats, R., Rinne, P., Salvermoser, M., Ring, L., Bianchini, M., Blanchet, X., Megens, R. T. A., Doring, Y., Walzog, B., Soehnlein, O., Weber, C., Faussner, A., & Steffens, S. (2018). Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1007-1019. https://doi.org/10.1161/ATVBAHA.117.310536
    • Geraets, I. M. E., Chanda, D., van Tienen, F. H. J., van den Wijngaard, A., Kamps, R., Neumann, D., Liu, Y., Glatz, J. F. C., Luiken, J. J. F. P., & Nabben, M. (2018). Human embryonic stem cell-derived cardiomyocytes as an in vitro model to study cardiac insulin resistance. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1864(5), 1960-1967. https://doi.org/10.1016/j.bbadis.2017.12.025
    • Boere, H., Eijsvoogel, N. G., Sailer, A. M., Wildberger, J. E., de Haan, M. W., Das, M., & Jeukens, C. R. L. P. N. (2018). Implementation of Size-Dependent Local Diagnostic Reference Levels for CT Angiography. American Journal of Roentgenology, 210(5), W226-W233. https://doi.org/10.2214/AJR.17.18566
    • Loos, C. M. J., Makin, S. D. J., Staals, J., Dennis, M. S., van Oostenbrugge, R. J., & Wardlaw, J. M. (2018). Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging. Stroke, 49(5), 1183–1188. https://doi.org/10.1161/STROKEAHA.117.020495
    • Hendriks, B. M. F., Eijsvoogel, N. G., Kok, M., Martens, B., Wildberger, J. E., & Das, M. (2018). Optimizing Pulmonary Embolism Computed Tomography in the Age of Individualized Medicine A Prospective Clinical Study. Investigative Radiology, 53(5), 306-312. https://doi.org/10.1097/RLI.0000000000000443
    • Steinbuch, J., Schreuder, F. H. B. M., Reesink, K. D., Hoeks, A. P. G., & Mess, W. H. (2018). ORTHOGONAL B-MODE EVALUATION OF COMMON CAROTID ARTERY PLAQUES REVEALS THE ABSENCE OF OUTWARD REMODELING. Ultrasound in Medicine and Biology, 44(5), 986-994. https://doi.org/10.1016/j.ultrasmedbio.2017.12.013
    • Rech, M., Aizpurua, A. B., van Empel, V., van Bilsen, M., & Schroen, B. (2018). Pathophysiological understanding of HFpEF: microRNAs as part of the puzzle. Cardiovascular Research, 114(6), 782-793. https://doi.org/10.1093/cvr/cvy049
    • Bisha, M., Dao, T.-V., Gholamreza-Fahimi, E., Vogt, M., van Zandvoort, M., Weber, S., Bas, M., Khosravani, F., Kojda, G., & Suvorava, T. (2018). The role of bradykinin receptor type 2 in spontaneous extravasation in mice skin: implications for non-allergic angio-oedema. British Journal of Pharmacology, 175(10), 1607-1620. https://doi.org/10.1111/bph.14166
    • Sedding, D. G., Boyle, E. C., Demandt, J. A. F., Sluimer, J. C., Dutzmann, J., Haverich, A., & Bauersachs, J. (2018). Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease. Frontiers in Immunology, 9(APR), Article 706. https://doi.org/10.3389/fimmu.2018.00706
    • Kimberly, W. T., Dutra, B. G., Boers, A. M. M., Alves, H. C. B. R., Berkhemer, O. A., van den Berg, L., Sheth, K. N., Roos, Y. B. W. E. M., van der Lugt, A., Beenen, L. F. M., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Marquering, H., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). Association of Reperfusion With Brain Edema in Patients With Acute Ischemic Stroke A Secondary Analysis of the MR CLEAN Trial. JAMA Neurology, 75(4), 453-461. https://doi.org/10.1001/jamaneurol.2017.5162
    • Peeters, F. E. C. M., van Mourik, M. J. W., Meex, S. J. R., Bucerius, J., Schalla, S. M., Gerretsen, S. C., Mihl, C., Dweck, M. R., Schurgers, L. J., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using F-18-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients, 10(4), Article 386. https://doi.org/10.3390/nu10040386
    • Dijkland, S. A., Voormolen, D. C., Venema, E., Roozenbeek, B., Polinder, S., Haagsma, J. A., Nieboer, D., Chalos, V., Yoo, A. J., Schreuders, J., van der Lugt, A., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Zwam, W. H., van Oostenbrugge, R. J., Steyerberg, E. W., Dippel, D. W. J., Lingsma, H. F., & MR CLEAN Investigators (2018). Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials A Simulation Study. Stroke, 49(4), 965-971. https://doi.org/10.1161/STROKEAHA.117.020194
    • Leunissen, T., van Vriesland, D., den Ruijter, H., Moll, F., Mess, W., & de Borst, G. J. (2018). Validation of the Automated Electronic Microemboli Detection System in Patients Undergoing Carotid Endarterectomy. Ultraschall in der Medizin (Stuttgart, Germany : 1980), 39(2), 198-205. https://doi.org/10.1055/s-0043-106737
    • Lacy, M., Kontos, C., Brandhofer, M., Hille, K., Groning, S., Sinitski, D., Bourilhon, P., Rosenberg, E., Krammer, C., Thavayogarajah, T., Pantouris, G., Bakou, M., Weber, C., Lolis, E., Bernhagen, J., & Kapurniotu, A. (2018). Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Scientific Reports, 8(1), Article 5171. https://doi.org/10.1038/s41598-018-23554-5
    • Jansen, I. G. H., Mulder, M. J. H. L., Goldhoorn, R.-J. B., Emmer, B. J., van Es, A. C. G. M., Roozenbeek, B., Schonewille, W. J., van den Berg, R., Coutinho, J. M., Staals, J., Postma, A. A., Lycklama, G. J., Hofmeijer, J., Martens, J. M., den Hertog, H. M., Sturm, F. J. C., van der Worp, H. B., Lo, R. H., Heijboer, R. J. J., ... MR CLEAN Registry Investigators (2018). Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry). BMJ, 360, Article 949. https://doi.org/10.1136/bmj.k949
    • Verdonschot, J. A. J., Hazebroek, M. R., Derks, K. W. J., Aizpurua, A. B., Merken, J. J., Wang, P., Bierau, J., van den Wijngaard, A., Schalla, S. M., Hamid, M. A. A., van Bilsen, M., van Empel, V. P. M., Knackstedt, C., Brunner-La Rocca, H.-P., Brunner, H. G., Krapels, I. P. C., & Heymans, S. R. B. (2018). Titin cardiomyopathy leads to altered mitochondrial energetics, increased fibrosis and long-termlife-threatening arrhythmias. European Heart Journal, 39(10), 864-873. https://doi.org/10.1093/eurheartj/ehx808
    • Aizpurua, A. B., Franssen, F. M. E., van Empel, V., & Brunner-La Rocca, H.-P. (2018). An old debate still in the beta-phase?European journal of heart failure, 20(3), 557-559. https://doi.org/10.1002/ejhf.1086
    • Douven, E., Kohler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. R. J., & Aalten, P. (2018). Baseline Vascular Cognitive Impairment Predicts the Course of Apathetic Symptoms After Stroke: The CASPER Study. American Journal of Geriatric Psychiatry, 26(3), 291-300. https://doi.org/10.1016/j.jagp.2017.09.022
    • Wetzels, S., Bijnen, M., Wijnands, E., Biessen, E. A. L., Schalkwijk, C. G., & Wouters, K. (2018). Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry. Journal of visualized experiment, (133), Article e57319 . https://doi.org/10.3791/57319
    • Henatsch, D., Alsulami, S., Duijvestijn, A. M., Cleutjens, J. P., Peutz-Kootstra, C. J., & Stokroos, R. J. (2018). Histopathological and Inflammatory Features of Chronically Discharging Open Mastoid Cavities Secondary Analysis of a Randomized Clinical Trial. JAMA Otolaryngology - Head and Neck Surgery, 144(3), 211-217. https://doi.org/10.1001/jamaoto.2017.2801
    • Maracle, C. X., Agca, R., Helder, B., Meeuwsen, J. A. L., Niessen, H. W. M., Biessen, E. A. L., de Winther, M. P. J., de Jager, S. C. A., Nurmohamed, M. T., & Tas, S. W. (2018). Noncanonical NF-kappa B signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction. Atherosclerosis, 270, 33-41. https://doi.org/10.1016/j.atherosclerosis.2018.01.032
    • Gombert, A., Grommes, J., Hilkman, D., Kotelis, D., Mess, W. H., & Jacobs, M. J. (2018). Recovery of lost motor evoked potentials in open thoracoabdominal aortic aneurysm repair using intercostal artery bypass. Journal of Vascular Surgery Cases and Innovative Techniques, 4(1), 54-57. https://doi.org/10.1016/j.jvscit.2017.12.004
    • Houben, R., Schreuder, F. H. B. M., Bekelaar, K. J., Claessens, D., van Oostenbrugge, R. J., & Staals, J. (2018). Predicting Prognosis of Intracerebral Hemorrhage (ICH): Performance of ICH Score Is Not Improved by Adding Oral Anticoagulant Use. Frontiers in Neurology, 9(FEB), Article 100. https://doi.org/10.3389/fneur.2018.00100
    • Horckmans, M., Bianchini, M., Santovito, D., Megens, R. T. A., Springael, J.-Y., Negri, I., Vacca, M., Di Eusanio, M., Moschetta, A., Weber, C., Duchene, J., & Steffens, S. (2018). Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction. Circulation, 137(9), 948-960. https://doi.org/10.1161/CIRCULATIONAHA.117.028833
    • Seijkens, T. T. P., van Tiel, C. M., Kusters, P. J. H., Atzler, D., Soehnlein, O., Zarzycka, B., Aarts, S. A. B. M., Lameijer, M., Gijbels, M. J., Beckers, L., den Toom, M., Slutter, B., Kuiper, J., Duchene, J., Aslani, M., Megens, R. T. A., van 't Veer, C., Kooij, G., Schrijver, R., ... Lutgens, E. (2018). Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. Journal of the American College of Cardiology, 71(5), 527-542. https://doi.org/10.1016/j.jacc.2017.11.055