• 2010
    • Kornmann, L. M., Reesink, K. D., Reneman, R. S., & Hoeks, A. P. G. (2010). CRITICAL APPRAISAL OF TARGETED ULTRASOUND CONTRAST AGENTS FOR MOLECULAR IMAGING IN LARGE ARTERIES. Ultrasound in Medicine and Biology, 36(2), 181-191. https://doi.org/10.1016/j.ultrasmedbio.2009.09.009
    • Lip, G. Y. H., Nieuwlaat, R., Pisters, R., Lane, D. A., & Crijns, H. J. G. M. (2010). Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach The Euro Heart Survey on Atrial Fibrillation. Chest, 137(2), 263-272. https://doi.org/10.1378/chest.09-1584
    • Wouters, K., van Bilsen, M., van Gorp, P. J., Bieghs, V., Lutjohann, D., Kerksiek, A., Staels, B., Hofker, M. H., & Sverdlov, R. (2010). Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice.Febs Letters, 584(5), 1001-1005. https://doi.org/10.1016/j.febslet.2010.01.046
    • van Rooij, E., Fielitz, J., Sutherland, L. B., Thijssen, V. L., Crijns, H. J., Dimaio, M. J., Shelton, J., De Windt, L. J., Hill, J. A., & Olson, E. N. (2010). Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor. Circulation Research, 106(1), 155-U315. https://doi.org/10.1161/CIRCRESAHA.109.207084
    • Johnson, D. M., Heijman, J., Pollard, C. E., Valentin, J. P., Crijns, H. J., Abi-Gerges, N., & Volders, P. G. A. (2010). I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation. Journal of Molecular and Cellular Cardiology, 48(1), 122-130. https://doi.org/10.1016/j.yjmcc.2009.08.033
    • Hermeling, E., Hoeks, A. P. G., Winkens, M. H. M., Waltenberger, J. L., Reneman, R. S., Kroon, A. A., & Reesink, K. D. (2010). Noninvasive Assessment of Arterial Stiffness Should Discriminate Between Systolic and Diastolic Pressure Ranges. Hypertension, 55(1), 124-130. https://doi.org/10.1161/HYPERTENSIONAHA.109.143867
    • Simons, A. P., Reesink, K. D., Lance, M. D., van der Nagel, T., van der Veen, F. H., Weerwind, P. W., & Maessen, J. G. (2010). Reserve-driven flow control for extracorporeal life support: proof of principle. Perfusion, 25(1), 25-29. https://doi.org/10.1177/0267659109360284
    • Lemmert, M. E., Majidi, M., Krucoff, M. W., Bekkers, S. C. A. M., Crijns, H. J. G. M., Wellens, H. J. J., Kosinski, A. S., & Gorgels, A. P. M. (2010). RR-interval irregularity precedes ventricular fibrillation in ST elevation acute myocardial infarction. Heart Rhythm, 7(1), 65-71. https://doi.org/10.1016/j.hrthm.2009.09.024
    • Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R.-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516
    • Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672
    • Simons, J. M. M., Kornmann, L. M., Reesink, K. D., Hoeks, A. P. G., Kemmere, M. F., Meuldijk, J., & Keurentjes, J. T. F. (2010). Monodisperse perfluorohexane emulsions for targeted ultrasound contrast imaging. Journal of Materials Chemistry, 20(19), 3918-3923. https://doi.org/10.1039/b922437h
    • Röther, J., & Crijns, H. (2010). Prevention of Stroke in Patients with Atrial Fibrillation: The Role of New Antiarrhythmic and Antithrombotic Drugs. Cerebrovascular Diseases, 30(3), 314-322. https://doi.org/10.1159/000319608
  • 2009
    • Lecut, C., Frederix, K., Johnson, D. M., Deroanne, C., Thiry, M., Faccinetto, C., Marée, R., Evans, R. J., Volders, P. G. A., Bours, V., & Oury, C. (2009). P2X1 ion channels promote neutrophil chemotaxis through Rho kinase activation. Journal of Immunology, 183(4), 2801-9. https://doi.org/10.4049/jimmunol.0804007
    • Been, J. V., Robben, S. G., Delhaas, T., Theunissen, P., Dompeling, E. D., & Jöbsis, Q. (2009). A 3-year-old female with cough, dyspnoea and low-grade fever. European Respiratory Journal, 33(3), 690-3. https://doi.org/10.1183/09031936.00074108
    • Driesen, R. B., Verheyen, F. K., Schaart, G., de Maziere, A., Viebahn, C., Prinzen, F. W., Lenders, M. H., Debie, W., Totzeck, A., Borgers, M., & Ramaekers, F. C. (2009). Cardiotin localization in mitochondria of cardiomyocytes in vivo and in vitro and its down-regulation during dedifferentiation. Cardiovascular Pathology, 18(1), 19-27. https://doi.org/10.1016/j.carpath.2007.12.008
    • Tintu, A., Rouwet, E., Verlohren, S., Brinkmann, J., Ahmad, S., Crispi, F., van Bilsen, M., Carmeliet, P., Staff, A. C., Tjwa, M., Cetin, I., Gratacos, E., Hernandez Andrade, E., Hofstra, L., Jacobs, M. J., Lamers, W. H., Morano, I., Safak, E., Ahmed, A., & le Noble, F. (2009). Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences. PLOS ONE, 4(4), Article e5155. https://doi.org/10.1371/journal.pone.0005155
    • Brouwers, M. C., Reesink, K. D., van Greevenbroek, M. M., Meinders, J. M., van der Kallen, C. J., Schaper, N., Hoeks, A. P., & Stehouwer, C. D. (2009). Increased arterial stiffness in familial combined hyperlipidemia. Journal of Hypertension, 27(5), 1009-16. https://doi.org/10.1097/HJH.0b013e32832991fa
  • 2008
    • Wouters, K., van Gorp, P. J. J., Bieghs, V., Gijbels, M. J., Duimel, H., Lutjohann, D., Kerksiek, A., van Kruchten, R., Maeda, N., Staels, B., van Bilsen, M., Sverdlov, R., & Hofker, M. H. (2008). Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology, 48(2), 474-486. https://doi.org/10.1002/hep.22363
    • Smeets, P. J. H., Teunissen, B. E. J., Willemsen, P. H. M., van Nieuwenhoven, F. A., Brouns, A. E., Janssen, B. J. A., Cleutjens, J. P. M., Staels, B., van der Vusse, G. J., & van Bilsen, M. (2008). Cardiac hypertrophy is enhanced in PPAR alpha-/- mice in response to chronic pressure overload. Cardiovascular Research, 78(1), 79-89. https://doi.org/10.1093/cvr/cvn001
    • Drost, M. R., Schaart, G., van Dijk, P., van Capelle, C. I., van der Vusse, G. J., Delhaas, T., van der Ploeg, A. T., & Reuser, A. J. (2008). Both type 1 and type 2a muscle fibers can respond to enzyme therapy in Pompe disease. Muscle & Nerve, 37(2), 251-5. https://doi.org/10.1002/mus.20896
    • Mihl, C., Dassen, W. R., & Kuipers, H. (2008). Cardiac remodelling: concentric versus eccentric hypertrophy in strength and endurance athletes. Netherlands Heart Journal, 16(4), 129-33. https://doi.org/10.1007/BF03086131
    • Smeets, P. J., de Vogel van de Bosch, H. M., Willemsen, P. H., Stassen, A. P., Ayoubi, T., van der Vusse, G. J., & van Bilsen, M. (2008). Transcriptomic analysis of PPARalpha-dependent alterations during cardiac hypertrophy.Physiological genomics, 36(1), 15-23. https://doi.org/10.1152/physiolgenomics.90296.2008
  • 2007
    • Donker, D. W., Maessen, J. G., Spätjens, R. L. H., van der Nagel, T., de Jong, M. M., Ramaekers, F. C., Crijns, H. J. G. M., Vos, M. A., & Volders, P. G. A. (2007). Serial left-ventricular biopsy sampling using a minimally invasive trans-thoracic approach in adult dogs. Pflugers Archiv-European Journal of Physiology, 454(6), 1043-1051. https://doi.org/10.1007/s00424-007-0261-z
    • Donker, D. W., Maessen, J. G., Verheyen, F., Ramaekers, F., Spätjens, R. L. H., Kuijpers, R., Rarnakers, C., Schiffers, P. M. H., Vos, M. A., Crijns, H. J. G. M., & Volders, P. G. A. (2007). Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. American Journal of Physiology-heart and Circulatory Physiology, 292(5), H2324-H2332. https://doi.org/10.1152/ajpheart.00392.2006
    • Schins, A., Crijns, H. J., Brummer, R. J., Wichers, M., Lousberg, R., Celis, S., & Honig, A. (2007). Altered omega-3 polyunsaturated fatty acid status in depressed post-myocardial infarction patients. Acta Psychiatrica Scandinavica, 115(1), 35-40. https://doi.org/10.1111/j.1600-0447.2006.00830.x
  • 2006
    • Stengl, M., Ramakers, C., Donker, D. W., Nabar, A., Rybin, A. V., Spätjens, R. L. H., van der Nagel, T., Wodzig, W., Sipido, K. R., Antoons, G., Moorman, A. F. M., Vos, M. A., & Volders, P. G. A. (2006). Temporal patterns of electrical remodeling in canine ventricular hypertrophy: Focus on I-Ks downregulation and blunted beta-adrenergic activation. Cardiovascular Research, 72(1), 90-100. https://doi.org/10.1016/j.cardiores.2006.07.015
    • Kuiper, E. J., de Smet, M. D., van Meurs, J. C., Tan, H. S., Tanck, M. W. T., Oliver, N., van Nieuwenhoven, F. A., Goldschmeding, R., & Schlingemann, R. O. (2006). Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye. Archives of Ophthalmology, 124(10), 1457-62. https://doi.org/10.1001/archopht.124.10.1457
    • Vanagt, W. Y., Cornelussen, R. N., Poulina, Q. P., Blaauw, E., Vernooy, K., Cleutjens, J. P., van Bilsen, M., Delhaas, T., & Prinzen, F. W. (2006). Pacing-induced dys-synchrony preconditions rabbit myocardium against ischemia/reperfusion injury. Circulation, 114(1 Suppl), I264-9. https://doi.org/10.1161/CIRCULATIONAHA.105.000893
    • Roestenberg, P., van Nieuwenhoven, F. A., Joles, J. A., Trischberger, C., Martens, P. P., Oliver, N., Aten, J., Höppener, J. W., & Goldschmeding, R. (2006). Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice. American Journal of Physiology-Renal Physiology, 290(6), F1344-54. https://doi.org/10.1152/ajprenal.00174.2005
    • Nguyen, T. Q., Chon, H., van Nieuwenhoven, F. A., Braam, B., Verhaar, M. C., & Goldschmeding, R. (2006). Myofibroblast progenitor cells are increased in number in patients with type 1 diabetes and express less bone morphogenetic protein 6: a novel clue to adverse tissue remodelling?Diabetologia, 49(5), 1039-48. https://doi.org/10.1007/s00125-006-0172-0
    • Shiri-Sverdlov, R., Wouters, K., van Gorp, P. J. J., Gijbels, M. J. J., Noel, B., Buffat, L., Staels, B., Maeda, N., van Bilsen, M., & Hofker, M. H. (2006). Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. Journal of Hepatology, 44(4), 732-741. https://doi.org/10.1016/j.jhep.2005.10.033
    • Brinkmann, J. F. F., Pelsers, M. M. A. L., van Nieuwenhoven, F. A., Tandon, N. N., van der Vusse, G. J., & Glatz, J. F. C. (2006). Purification, immunochemical quantification and localization in rat heart of putative fatty acid translocase (FAT/CD36). Molecular and Cellular Biochemistry, 284(1-2), 127-34. https://doi.org/10.1007/s11010-005-9033-2
    • van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M., & Evelo, C. T. (2006). Biologically relevant effects of mRNA amplification on gene expression profiles. BMC Bioinformatics, 7, 200. https://doi.org/10.1186/1471-2105-7-200
    • Sen, S., Rose, C., Ytrebo, L. M., Davies, N. A., Nedredal, G. I., Drevland, S. S., Kjonno, M., Prinzen, F. W., Hodges, S. J., Deutz, N. E. P., Williams, R., Butterworth, R. F., Revhaug, A., & Jalan, R. A. (2006). Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study. Critical Care Medicine, 34(1), 158-164. https://doi.org/10.1097/01.CCM.0000196203.39832.3C
    • van Empel, V. P. M., Bertrand, A. T., van Oort, R. J., van der Nagel, R., Engelen, M. P. K. J., van Rijen, H. V., Doevendans, P. A. F. M., Crijns, H. J. G. M., Ackerman, S. L., Sluiter, W., & de Windt, L. J. (2006). EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. Journal of the American College of Cardiology, 48(4), 824-832. https://doi.org/10.1016/j.jacc.2006.02.075
    • Ytrebo, L. M., Sen, S., Rose, C., Davies, N. A., Nedredal, G. I., Fuskevaag, O. M., ten Have, G. A. M., Prinzen, F. W., Williams, R., Deutz, N. E., Jalan, R., & Revhaug, A. (2006). Systemic and regional haemodynamics in pigs with acute liver failure and the effect of albumin dialysis. Scandinavian Journal of Gastroenterology, 41(11), 1350-1360. https://doi.org/10.1080/00365520600714527
    • Nguyen, T. Q., Tarnow, L., Andersen, S., Hovind, P., Parving, H.-H., Goldschmeding, R., & van Nieuwenhoven, F. A. (2006). Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy. Diabetes Care, 29(1), 83-8. https://doi.org/10.2337/diacare.29.1.83
  • 2005
    • Donker, D. W., Volders, PGA., Arts, T., Bekkers, BBACM., Hofstra, L., Spätjens, R. L. H., Beekman, J. D. M., Borgers, M., Crijns, HJGM., & Vos, MA. (2005). End-diastolic myofiber stress and ejection strain increase with ventricular volume overload. Basic Research in Cardiology, 100(4), 372-382. https://doi.org/10.1007/s00395-005-0525-8
    • Van Berlo, J. H., Voncken, M. J. W. M., Kubben, N., Broers, J. L. V., Duisters, R. F. J. J., van Leeuwen, R. E., Crijns, H. J. G. M., Ramaekers, F. C. S., Hutchison, C. J., & Pinto, Y. M. (2005). A-type lamins are essential for TGF-beta1 induced PP2A to dephosphorylate transcription factors.Human Molecular Genetics, 14(19), 2839-2849. https://doi.org/10.1093/hmg/ddi316
    • Wouters, K. A. M., Shiri-Sverdlov, R., van Gorp, P. J. J., van Bilsen, M., & Hofker, M. H. (2005). Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice. Clinical Chemistry and Laboratory Medicine, 43(5), 470-479. https://doi.org/10.1515/CCLM.2005.085
    • Ramakers, C., Stengl, M., Spätjens, R. L. H., Moorman, A. F. M., & Vos, MA. (2005). Molecular and electrical characterization of the canine cardiac ventricular septum. Journal of Molecular and Cellular Cardiology, 38(1), 153-161. https://doi.org/10.1016/j.yjmcc.2004.10.011
  • 2004
    • Sharma, U. C., Pokharel, S., van Brakel, T. J., van Berlo, J. H., Cleutjens, J. P. M., Schroen, B., André, S., Crijns, H. J. G. M., Gabius, H.-J., Maessen, J., & Pinto, Y. M. (2004). Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation, 110(19), 3121-8. https://doi.org/10.1161/01.CIR.0000147181.65298.4D
    • Pokharel, S., van Geel, P. P., Sharma, U. C., Cleutjens, J. P. M., Bohnemeier, H., Tian, X.-L., Schunkert, H., Crijns, H. J. G. M., Paul, M., & Pinto, Y. M. (2004). Increased myocardial collagen content in transgenic rats overexpressing cardiac angiotensin-converting enzyme is related to enhanced breakdown of N-acetyl-Ser-Asp-Lys-Pro and increased phosphorylation of Smad2/3. Circulation, 110(19), 3129-35. https://doi.org/10.1161/01.CIR.0000147180.87553.79
    • Verduijn, S., Jungschleger, JGM., Stengl, M., Spätjens, R. L. H., Beekman, J. D. M., & Vos, MA. (2004). Electrophysiological and proarrhythmic parameters in transmural canine left-ventricular needle biopsies. Pflugers Archiv-European Journal of Physiology, 449(1), 115-122. https://doi.org/10.1007/s00424-004-1306-1
    • Schroen, B., Heymans, S., Sharma, U., Blankesteijn, W. M., Pokharel, S., Cleutjens, J. P. M., Porter, J. G., Evelo, C. T. A., Duisters, R., van Leeuwen, R. E. W., Janssen, B. J. A., Debets, J. J. M., Smits, J. F. M., Daemen, M. J. A. P., Crijns, H. J. G. M., Bornstein, P., & Pinto, Y. M. (2004). Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy. Circulation Research, 95(5), 515-522. https://doi.org/10.1161/01.RES.0000141019.20332.3e
  • 2003
    • Thomsen, M. B., Volders, PGA., Stengl, M., Spätjens, R. L. H., Beekman, J. D. M., Bischoff, U., Kall, MA., Frederiksen, K., Matz, J., & Vos, MA. (2003). Electrophysiological safety of sertindole in dogs with normal and remodeled hearts. Journal of Pharmacology and Experimental Therapeutics, 307(2), 776-784. https://doi.org/10.1124/jpet.103.052753
    • Stengl, M., Volders, PGA., Thomsen, M. B., Spätjens, R. L. H., Sipido, K. R., & Vos, MA. (2003). Accumulation of slowly activating delayed rectifier potassium current(I-Ks) canine ventricular myocytes. Journal of Physiology, 551(3), 777-786. https://doi.org/10.1113/jphysiol.2003.044040