• 2024
    • Velt, M. J. H., Crijns, H. J. G. M., van Gelder, I. C., Linz, D., van de Lande, M. E., Ten Cate, H., Spronk, H. M. H., de Melis, M., Rienstra, M., & Mulder, B. A. (2024). Dynamic biomarker profiles in patients with paroxysmal atrial fibrillation: Assessing the differences between sinus rhythm and acute atrial fibrillation episode. International Journal of Cardiology, 417, Article 132526. https://doi.org/10.1016/j.ijcard.2024.132526
    • Hutschalik, T., Özgül, O., Casini, M., Szabó, B., Peyronnet, R., Bártulos, Ó., Argenziano, M., Schotten, U., & Matsa, E. (2024). Immune response caused by M1 macrophages elicits atrial fibrillation-like phenotypes in coculture model with isogenic hiPSC-derived cardiomyocytes. Stem Cell Research & Therapy, 15(1), Article 280. https://doi.org/10.1186/s13287-024-03814-0
    • Neuen, S. M. L., Ophelders, D. R. M. G., Widowski, H., Hütten, M. C., Brokken, T., van Gorp, C., Nikkels, P. G. J., Severens-Rijvers, C. A. H., Sthijns, M. M. J. P. E., van Blitterswijk, C. A., Troost, F. J., LaPointe, V. L. S., Jolani, S., Seiler, C., Pillow, J. J., Delhaas, T., Reynaert, N. L., & Wolfs, T. G. A. M. (2024). Multipotent adult progenitor cells prevent functional impairment and improve development in inflammation driven detriment of preterm ovine lungs. Regenerative Therapy, 27, 207-217. https://doi.org/10.1016/j.reth.2024.03.014
    • Vernooy, K., van Stipdonk, A. M. W., & Joza, J. (2024). People with cardiac pacemakers require multidisciplinary care. Nature Medicine. Advance online publication. https://doi.org/10.1038/s41591-024-03296-w
    • Ramos-Prada, A., Redondo-Rodríguez, A., Roca-Luque, I., Porta-Sánchez, A., Ter Bekke, R. M. A., Quintanilla, J. G., Sánchez-González, J., Peinado, R., Merino, J. L., Cluitmans, M., Holtackers, R. J., Marina-Breysse, M., Galán-Arriola, C., Enríquez-Vázquez, D., Vázquez-Calvo, S., Alfonso-Almazán, J. M., Pizarro, G., Ibáñez, B., González-Ferrer, J. J., ... Filgueiras-Rama, D. (2024). Novel systematic processing of cardiac magnetic resonance imaging identifies target regions associated with infarct-related ventricular tachycardia. EP Europace, 26(10), Article euae244. https://doi.org/10.1093/europace/euae244
    • Aerts, L., Kawczynski, M. J., Bidar, E., Luermans, J., Chaldoupi, M., La Meir, M., Kowaleski, M., Maessen, J. G., Heuts, S., & Maesen, B. (2024). Short- and long-term outcomes in isolated vs. hybrid thoracoscopic ablation in patients with atrial fibrillation: a systematic review and reconstructed individual patient data meta-analysis. EP Europace, 26(10), Article euae232. https://doi.org/10.1093/europace/euae232
    • Neutel, C. H. G., Wesley, C. D., van Loo, C., Civati, C., Mertens, F., Zurek, M., Verhulst, A., Pintelon, I., De Vos, W. H., Spronck, B., Roth, L., De Meyer, G. R. Y., Martinet, W., & Guns, P. J. (2024). Calciprotein particles induce arterial stiffening ex vivo and impair vascular cell function. Communications Biology, 7(1), Article 1241. https://doi.org/10.1038/s42003-024-06895-y
    • Gottlieb, L. A., Mahfoud, F., Stavrakis, S., Jespersen, T., & Linz, D. (2024). Autonomic Nervous System: A Therapeutic Target for Cardiac End-Organ Damage in Hypertension. Hypertension, 81(10), 2027-2037. Article 19460. https://doi.org/10.1161/HYPERTENSIONAHA.123.19460
    • D'Italia, G., Schroen, B., & Cosemans, J. M. E. M. (2024). Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities. Esc heart failure, Article 15090. https://doi.org/10.1002/ehf2.15090
    • Sharma, S. P., Lemmens, M.-J. D. K., Smulders, M. W., Budde, R. P. J., Hirsch, A., & Mihl, C. (2024). Photon-counting detector computed tomography in cardiac imaging. Netherlands Heart Journal. https://doi.org/10.1007/s12471-024-01904-5
    • Verheul, L. M., Hoeksema, W. F., Groeneveld, S. A., Mulder, B. A., Bootsma, M., Alings, M., Evertz, R., Blank, A. C., Kammeraad, J. A. E., Clur, S.-A. B., Yap, S.-C., Postema, P. G., Wilde, A. A. M., Volders, P. G. A., & Hassink, R. J. (2024). Comparing Adolescent- and Adult-Onset Unexplained Cardiac Arrest - Results from the Dutch Idiopathic VF registry. Heart Rhythm, 21(10), 1779-1786. https://doi.org/10.1016/j.hrthm.2024.03.031
    • Chaldoupi, S.-M., Nissen, S. D., Vriesendorp, P. A., Jerltorp, K., Farnir, F. I. P., Linz, B., Johannessen, A., Haugdal, M. A., Luermans, J. G. L. M., Saljic, A., Jespersen, T., Hansen, J., & Linz, D. (2024). Focal monopolar pulsed field ablation from within the great cardiac vein for idiopathic premature ventricular contractions after failed radiofrequency ablation. Heart Rhythm, 21(10), 1877-1887. https://doi.org/10.1016/j.hrthm.2024.07.002
    • Bijvoet, G. P., Hermans, B. J. M., Linz, D., Luermans, J. G. L. M., Maesen, B., Nijveldt, R., Mihl, C., Vernooy, K., Wildberger, J. E., Holtackers, R. J., Schotten, U., & Chaldoupi, S.-M. (2024). Optimal Threshold and Interpatient Variability in Left Atrial Ablation Scar Assessment by Dark-Blood LGE CMR. JACC: Clinical Electrophysiology, 10(10), 2186-2197. https://doi.org/10.1016/j.jacep.2024.05.017
    • Sandgren, E., Hermans, A. N., Gawalko, M., Betz, K., Sohaib, A., Fung, C. H., Hillmann, H. A., van der Velden, R. M., Verhaert, D., Scherr, D., Sultan, A., Steven, D., Pisters, R., Hemels, M., Lodzinski, P., Chaldoupi, S.-M., Gupta, D., Gruwez, H., Pluymaekers, N. A., ... TeleCheck-AF investigators (2024). Smartphone app-based approximation of time spent with atrial fibrillation and symptoms in patients after catheter ablation: Data from the TeleCheck-AF project. EP Europace, 26(10), Article euae247. https://doi.org/10.1093/europace/euae247
    • Champsi, A., Mobley, A. R., Subramanian, A., Nirantharakumar, K., Wang, X., Shukla, D., Bunting, K., Molgaard, I., Dwight, J., Casado Arroyo, R., Crijns, H. J. G. M., Guasti, L., Lettino, M., Lumbers, R. T., Maesen, B., Rienstra, M., Svennberg, E., Tica, O., Traykov, V., ... Kotecha, D. (2024). Gender and contemporary risk of adverse events in atrial fibrillation. European Heart Journal, 45(36), 3707-3717. Article ehae539. https://doi.org/10.1093/eurheartj/ehae539
    • Vijayaraman, P., Zanon, F., Ponnusamy, S. S., Herweg, B., Sharma, P., Molina-Lerma, M., Jastrzebski, M., Whinnett, Z., Vernooy, K., Pathak, R. K., Tung, R., Upadhyay, G., Curila, K., Zalavadia, D., Shah, N., Marcantoni, L., Gad, M., Morcos, R., Moskal, P., ... Cano, O. (2024). Conduction system pacing compared with biventricular pacing for cardiac resynchronization therapy in patients with heart failure and mildly reduced left ventricular ejection fraction: Results from International Collaborative LBBAP Study (I-CLAS) Group. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.09.030
    • Tohidinezhad, F., Nürnberg, L., Vaassen, F., Ma Ter Bekke, R., Jwl Aerts, H., El Hendriks, L., Dekker, A., De Ruysscher, D., & Traverso, A. (2024). Prediction of new-onset atrial fibrillation in patients with non-small cell lung cancer treated with curative-intent conventional radiotherapy. Radiotherapy and Oncology, 201, Article 110544. Advance online publication. https://doi.org/10.1016/j.radonc.2024.110544
    • Buonocunto, M., Lyon, A., Delhaas, T., Heijman, J., & Lumens, J. (2024). Electrophysiological effects of stretch-activated ion channels: a systematic computational characterization. The Journal of Physiology, 602(18), 4585-4604. https://doi.org/10.1113/JP284439
    • Jusic, A., Erpapazoglou, Z., Dalgaard, L. T., Lakkisto, P., de Gonzalo-Calvo, D., Benczik, B., Ágg, B., Ferdinandy, P., Fiedorowicz, K., Schroen, B., Lazou, A., Devaux, Y., & AtheroNET COST Action CA21153 (2024). Guidelines for mitochondrial RNA analysis. Molecular Therapy - Nucleic Acids, 35(3), Article 102262. https://doi.org/10.1016/j.omtn.2024.102262
    • Schnabel, R. B., Benezet-Mazuecos, J., Becher, N., McIntyre, W. F., Fierenz, A., Lee, S. F., Goette, A., Atar, D., Bertaglia, E., Benz, A. P., Chlouverakis, G., Birnie, D. H., Dichtl, W., Blomstrom-Lundqvist, C., Camm, A. J., Erath, J. W., Simantirakis, E., Kutyifa, V., Lip, G. Y. H., ... Kirchhof, P. (2024). Anticoagulation in device-detected atrial fibrillation with or without vascular disease: a combined analysis of the NOAH-AFNET 6 and ARTESiA trials. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae596
    • Rijks, J. H. J., Heckman, L., Westra, S., Cornelussen, R., Ghosh, S., Curila, K., Smisek, R., Grieco, D., Bressi, E., Nguyen, U. C., Lumens, J., van Stipdonk, A. M. W., Linz, D., Prinzen, F. W., Luermans, J. G. L. M., & Vernooy, K. (2024). Assessment of ventricular electrical heterogeneity in left bundle branch pacing and left ventricular septal pacing by using various electrophysiological methods. Journal of Cardiovascular Electrophysiology, Article 16435. https://doi.org/10.1111/jce.16435
    • Goette, A., Corradi, D., Dobrev, D., Aguinaga, L., Cabrera, J.-A., Chugh, S. S., de Groot, J. R., Soulat-Dufour, L., Fenelon, G., Hatem, S. N., Jalife, J., Lin, Y.-J., Lip, G. Y. H., Marcus, G. M., Murray, K. T., Pak, H.-N., Schotten, U., Takahashi, N., Yamaguchi, T., ... Nattel, S. (2024). Atrial Cardiomyopathy Revisited - Evolution of a Concept. A Clinical Consensus Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Association (APHRS), and the Latin American Heart Rhythm Society (LAHRS): a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS). EP Europace, 26(9), Article euae204. https://doi.org/10.1093/europace/euae204
    • Gawalko, M., Middeldorp, M. E., Saljic, A., Penders, J., Jespersen, T., Albert, C. M., Marcus, G. M., Wong, C. X., Sanders, P., & Linz, D. (2024). Diet and risk of atrial fibrillation: a systematic review. European Heart Journal, Article ehae551. https://doi.org/10.1093/eurheartj/ehae551
    • Paulussen, E., Van Steenkiste, G., Hermans, B. J. M., Decloedt, A., van Loon, G., & Delhaas, T. (2024). Einthoven's triangle adapted for horses: Proposal for the Delta configuration. Journal of Veterinary Internal Medicine, 38(5), 2698-2706. https://doi.org/10.1111/jvim.17179
    • Serinagaoglu Dogrusoz, Y., Bear, L., Bergquist, J. A., Rababah, A., Good, W., Stoks, J., Svehlikova, J., van Dam, E., Brooks, D. H., & MacLeod, R. (2024). Evaluation of five methods for the interpolation of bad leads in the solution of the inverse electrocardiography problem. Physiological Measurement, 45(9), Article 095012. https://doi.org/10.1088/1361-6579/ad74d6
    • Beela, A. S., Rijks, J. H. J., Manetti, C. A., Vernooy, K., van Stipdonk, A. M. W., Prinzen, F. W., Delhaas, T., Herbots, L., & Lumens, J. (2024). Left bundle branch block criteria in the 2021 ESC guidelines on CRT: A step back in identifying CRT candidates?European Heart Journal Cardiovascular Imaging, 25(9), e213-e215. https://doi.org/10.1093/ehjci/jeae164
    • Ghossein, M. A., de Kok, J. W. T. M., Eerenberg, F., van Rosmalen, F., Boereboom, R., Duisberg, F., Verharen, K., Sels, J. E. M., Delnoij, T., Geyik, Z., Mingels, A. M. A., Meex, S. J. R., van Kuijk, S. M. J., van Stipdonk, A. M. W., Ghossein, C., Prinzen, F. W., van der Horst, I. C. C., Vernooy, K., van Bussel, B. C. T., & Driessen, R. G. H. (2024). Monitoring of myocardial injury by serial measurements of QRS area and T area: The MaastrICCht cohort. Annals of Noninvasive Electrocardiology, 29(5), Article e70001. https://doi.org/10.1111/anec.70001
    • van Vliet, L. V., Zonnebeld, N., Tordoir, J. H., Huberts, W., Bouwman, L. H., Cuypers, P. W., Heinen, S. G., Huisman, L. C., Lemson, S., Mees, B. M. E., Schlosser, F. J., de Smet, A. A., Toorop, R. J., Delhaas, T., & Snoeijs, M. G. (2024). Guideline recommendations on minimal blood vessel diameters and arteriovenous fistula outcomes. Journal of vascular access, 25(5), 1584-1592. https://doi.org/10.1177/11297298231180627
    • Giudici, A., Szafron, J. M., Ramachandra, A. B., & Spronck, B. (2024). Instability in Computational Models of Vascular Smooth Muscle Cell Contraction. Annals of Biomedical Engineering, 52(9), 2403-2416. https://doi.org/10.1007/s10439-024-03532-x
    • Brandt, Y., Lubrecht, J. M., Adriaans, B. P., Aben, J.-P., Gerretsen, S. C., Ghossein-Doha, C., Spaanderman, M. E. A., Prinzen, F. W., & Kooi, M. E. (2024). Quantification of left ventricular myocardial strain: Comparison between MRI tagging, MRI feature tracking, and ultrasound speckle tracking. NMR in Biomedicine, 37(9), Article e5164. https://doi.org/10.1002/nbm.5164
    • van Vliet, L. V., Delhaas, T., Mees, B. M. E., & Snoeijs, M. G. (2024). Response letter. Journal of vascular access, 25(5), 1705-1707. https://doi.org/10.1177/11297298231218663
    • Parikh, S., Giudici, A., Huberts, W., Delhaas, T., Bidar, E., Spronck, B., & Reesink, K. (2024). Significance of Dynamic Axial Stretching on Estimating Biomechanical Behavior and Properties of the Human Ascending Aorta. Annals of Biomedical Engineering, 52(9), 2485-2495. https://doi.org/10.1007/s10439-024-03537-6
    • Malik, V., Linz, D., & Sanders, P. (2024). The Role of the Autonomic Nervous System as Both “Trigger and “Substrate” in Atrial Fibrillation. Cardiac Electrophysiology Clinics, 16(3), 271-280. https://doi.org/10.1016/j.ccep.2023.08.003
    • Fabritz, L., Al-Taie, C., Borof, K., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Roth Cardoso, V., Chua, W., van Elferen, S., Eckardt, L., Gkoutos, G., Goette, A., Guasch, E., Hatem, S., Metzner, A., Mont, L., Murukutla, V. A., Obergassel, J., Rillig, A., ... Kirchhof, P. (2024). Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae611
    • Sohns, C., Moersdorf, M., Marrouche, N. F., Bergau, L., Costard-Jaeckle, A., Crijns, H. J. G. M., Fox, H., Hindricks, G., Dagres, N., Sossalla, S., Schramm, R., Fink, T., El Hamriti, M., Sciacca, V., Didenko, M., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., ... CASTLE HTx Investigators (2024). Catheter Ablation in Patients with End-Stage Heart Failure and Atrial Fibrillation: Two-year Follow-up of the CASTLE-HTx Trial. Circulation. Advance online publication. https://doi.org/10.1161/CIRCULATIONAHA.124.071517
    • Cavinato, C., Spronck, B., Caulk, A. W., Murtada, S.-I., & Humphrey, J. D. (2024). AT1b receptors contribute to regional disparities in angiotensin II mediated aortic remodelling in mice. Journal of the Royal Society Interface, 21(217), Article 20240110. https://doi.org/10.1098/rsif.2024.0110
    • Diener, H. C., Becher, N., Sehner, S., Toennis, T., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G.-A., Dichtl, W., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lip, G. Y. H., Lubinski, A., ... NOAH-AFNET 6 investigators (2024). Anticoagulation in Patients With Device-Detected Atrial Fibrillation With and Without a Prior Stroke or Transient Ischemic Attack: The NOAH-AFNET 6 Trial. Journal of the American Heart Association, 13(17), e036429. https://doi.org/10.1161/JAHA.124.036429
    • Fakuade, F. E., Hubricht, D., Möller, V., Sobitov, I., Liutkute, A., Döring, Y., Seibertz, F., Gerloff, M., Pronto, J. R. D., Haghighi, F., Brandenburg, S., Alhussini, K., Ignatyeva, N., Bonhoff, Y., Kestel, S., El-Essawi, A., Jebran, A. F., Großmann, M., Danner, B. C., ... Voigt, N. (2024). Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation. Circulation, 150(7), 544-559. https://doi.org/10.1161/CIRCULATIONAHA.123.066577
    • Reyat, J. S., Sommerfeld, L. C., O'Reilly, M., Cardoso, V. R., Thiemann, E., Khan, A. O., O'Shea, C., Harder, S., Müller, C., Barlow, J., Stapley, R. J., Chua, W., Kabir, S. N., Grech, O., Hummel, O., Hübner, N., Kääb, S., Mont, L., Hatem, S. N., ... Fabritz, L. (2024). PITX2 deficiency leads to atrial mitochondrial dysfunction. Cardiovascular Research. Advance online publication. https://doi.org/10.1093/cvr/cvae169
    • Shahrbabaki, S. S., Dharmaprani, D., Tiver, K. D., Jenkins, E., Strong, C., Tonchev, I., O'Loughlin, L. P., Linz, D., Chapman, D., Lechat, B., Ullah, S., Stone, K. L., Eckert, D. J., Baumert, M., & Ganesan, A. N. (2024). Power-law properties of nocturnal arrhythmia avalanches: a novel marker for incident cardiovascular events. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.08.015
    • Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2024). Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.08.014
    • van de Kar, M. R. D., van Brakel, T. J., Van't Veer, M., van Steenbergen, G. J., Daeter, E. J., Crijns, H. J. G. M., van Veghel, D., Dekker, L. R. C., & Otterspoor, L. C. (2024). Anticoagulation for post-operative atrial fibrillation after isolated coronary artery bypass grafting: a meta-analysis. European Heart Journal, 45(29), 2620-2630. https://doi.org/10.1093/eurheartj/ehae267
    • Arslan, M., Schaap, J., van Gorsel, B., Aubanell, A., Budde, R. P. J., Hirsch, A., Smulders, M. W., Mihl, C., Damman, P., Sliwicka, O., Habets, J., Dubois, E. A., & Dedic, A. (2024). Coronary computed tomography angiography improves assessment of patients with acute chest pain and inconclusively elevated high-sensitivity troponins. European Radiology. Advance online publication. https://doi.org/10.1007/s00330-024-10930-1
    • van Veldhuisen, D. J., Rienstra, M., Mosterd, A., Alings, A. M., van Asselt, A. D. J., Bouvy, M. L., Tijssen, J. G. P., Schaap, J., van der Wall, E. E., Voors, A. A., Boorsma, E. M., Lok, D. J. A., Crijns, H. J. G. M., Schut, A., Vijver, M. A. T., Voordes, G. H. D., de Vos, A. H., Maas-Soer, E. L., Smit, N. W., ... DECISION Investigators & Commitees (2024). Efficacy and safety of low-dose digoxin in patients with heart failure. Rationale and design of the DECISION trial. European journal of heart failure. Advance online publication. https://doi.org/10.1002/ejhf.3428
    • Sanders, P., Svennberg, E., Diederichsen, S. Z., Crijns, H. J. G. M., Lambiase, P. D., Boriani, G., & Van Gelder, I. C. (2024). Great debate: device-detected subclinical atrial fibrillation should be treated like clinical atrial fibrillation. European Heart Journal, 45(29), 2594-2603. https://doi.org/10.1093/eurheartj/ehae365
    • Lenting, C. J., Wijtvliet, E. P. J. P., Koldenhof, T., Bessem, B., Pluymaekers, N. A. H. A., Rienstra, M., Folkeringa, R. J., Bronzwaer, P., Elvan, A., Elders, J., Tukkie, R., Luermans, J. G. L. M., Van Kuijk, S. M. J., Tijssen, J. G. P., Van Gelder, I. C., Crijns, H. J. G. M., & Tieleman, R. G. (2024). Previous Exercise Levels and Outcome in Patients with New Atrial Fibrillation: 'Past Achievements Do Not Predict the Future'. Medicine and Science in Sports and Exercise, 56(8), 1349-1354. https://doi.org/10.1249/MSS.0000000000003424
    • Linz, D., & Dobrev, D. (2024). Recent highlights from the International Journal of Cardiology heart & Vasculature: Comprehensive management of atrial fibrillation. IJC Heart and Vasculature, 53, Article 101478. https://doi.org/10.1016/j.ijcha.2024.101478
    • Linz, D., & Hermans, B. J. M. (2024). Remote technical support of nurse-lead electro-anatomic mapping during complex catheter ablation procedures. European Journal of Cardiovascular Nursing. Advance online publication. https://doi.org/10.1093/eurjcn/zvae108
    • Sabbag, A., Amoroso, G., Tomer, O., Conte, G., Beinart, R., Nof, E., Ozkartal, T., Ollitrault, P., Laredo, M., Tovia-Brodie, O., Gandjbakhch, E., de Benedictis, M., ter Bekke, R. M. A., & Milman, A. (2024). Clinical differences between drug-induced type 1 Brugada pattern and syndrome. Journal of Arrhythmia, 40(4), 982-990. https://doi.org/10.1002/joa3.13053
    • Welman, M. J. M., Streukens, S. A. F., Mephtah, A., Hoebers, L. P., Vainer, J., Theunissen, R., Heuts, S., Maessen, J. G., Segers, P., Vernooy, K., van 't Hof, A. W. J., Sardari Nia, P., & Vriesendorp, P. A. (2024). Outcomes of Mitral Valve Regurgitation Management after Expert Multidisciplinary Valve Team Evaluation. Journal of Clinical Medicine, 13(15), Article 4487. https://doi.org/10.3390/jcm13154487