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International Consortium for Blood Pressure Genome-Wide Association Studies (2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 478(7367), 103-109. https://doi.org/10.1038/nature10405

Soehnlein, O., Wantha, S., Simsekyilmaz, S., Doering, Y., Megens, R. T. A., Mause, S. F., Drechsler, M., Smeets, R., Weinandy, S., Schreiber, F., Gries, T., Jockenhoevel, S., Moeller, M., Vijayan, S., van Zandvoort, M. A. M. J., Agerberth, B., Pham, C. C. T. N., Gallo, R. L., Hackeng, T. M., ... Weber, C. (2011). Neutrophil-Derived Cathelicidin Protects from Neointimal Hyperplasia. Science Translational Medicine, 3(103), 10. https://doi.org/10.1126/scitranslmed.3002531

Surakka, I., Isaacs, A., Karssen, L. C., Laurila, P.-P. P., Middelberg, R. P. S., Tikkanen, E., Ried, J. S., Lamina, C., Mangino, M., Igl, W., Hottenga, J.-J., Lagou, V., van der Harst, P., Mateo Leach, I., Esko, T., Kutalik, Z., Wainwright, N. W., Struchalin, M. V., Sarin, A.-P., ... ENGAGE Consortium (2011). A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. Plos Genetics, 7(10), e1002333. https://doi.org/10.1371/journal.pgen.1002333

Bogaard, M. D., Houthuizen, P., Bracke, F. A., Doevendans, P. A., Prinzen, F. W., Meine, M., & van Gelder, B. M. (2011). Baseline left ventricular dP/dt(max) rather than the acute improvement in dP/dt(max) predicts clinical outcome in patients with cardiac resynchronization therapy. European journal of heart failure, 13(10), 1126-1132. https://doi.org/10.1093/eurjhf/hfr094

Weijs, B., Blaauw, Y., Rennenberg, R. J. M. W., Schurgers, L. J., Timmermans, C. C. M. M., Pison, L., Nieuwlaat, R., Hofstra, L., Kroon, A. A., Wildberger, J., & Crijns, H. J. G. M. (2011). Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. European Heart Journal, 32(20), 2555-2562. https://doi.org/10.1093/eurheartj/ehr226

Heinis, A. M. F., Spaanderman, M. E., Gunnewiek, J. M. T. K., & Lotgering, F. K. (2011). Scalp blood lactate for intra-partum assessment of fetal metabolic acidosis. Acta Obstetricia et Gynecologica Scandinavica, 90(10), 1107-1114. https://doi.org/10.1111/j.1600-0412.2011.01237.x

Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., Markus, H. S., Schmidt, R., Huffman, J. E., Lehtimäki, T., Baumert, J., Münzel, T., Heckbert, S. R., Dehghan, A., North, K., Oostra, B., ... CARDIoGRAM Consortium (2011). Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nature Genetics, 43(10), 940-7. https://doi.org/10.1038/ng.920

Reilly, S. N., Jayaram, R., Nahar, K., Antoniades, C., Verheule, S., Channon, K. M., Alp, N. J., Schotten, U., & Casadei, B. (2011). Atrial Sources of Reactive Oxygen Species Vary With the Duration and Substrate of Atrial Fibrillation Implications for the Antiarrhythmic Effect of Statins. Circulation, 124(10), 1107-U91. https://doi.org/10.1161/CIRCULATIONAHA.111.029223

Lim, A. C., Schuit, E., Bloemenkamp, K., Bernardus, R. E., Duvekot, J. J., Erwich, J. J. H. M., van Eyck, J., Groenwold, R. H. H., Hasaart, T. H. M., Hummel, P., Kars, M. M., Kwee, A., van Oirschot, C. M., van Pampus, M. G., Papatsonis, D. N. M., Porath, M., Spaanderman, M. E., Willekes, C., Wilpshaar, J., ... Bruinse, H. W. (2011). 17 alpha-Hydroxyprogesterone Caproate for the Prevention of Adverse Neonatal Outcome in Multiple Pregnancies. Obstetrics and Gynecology, 118(3), 513-520. https://doi.org/10.1097/AOG.0b013e31822ad6aa

Schuur, M., Ikram, M. A., van Swieten, J. C., Isaacs, A., Vergeer-Drop, J. M., Hofman, A., Oostra, B. A., Breteler, M. M. B., & van Duijn, C. M. (2011). Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis. Neurobiology of Aging, 32(9), 1607-14. https://doi.org/10.1016/j.neurobiolaging.2009.10.011

Linz, D., Schotten, U., Neuberger, H.-R., Boehm, M., & Wirth, K. (2011). Negative tracheal pressure during obstructive respiratory events promotes atrial fibrillation by vagal activation. Heart Rhythm, 8(9), 1436-1443. https://doi.org/10.1016/j.hrthm.2011.03.053

Heemstra, H. E., Nieuwlaat, R., Meijboom, M., & Crijns, H. J. (2011). The burden of atrial fibrillation in the Netherlands. Netherlands Heart Journal, 19(9), 373-378. https://doi.org/10.1007/s12471-011-0175-4

Kornfeld, J.-W., Isaacs, A., Vitart, V., Pospisilik, J. A., Meitinger, T., Gyllensten, U., Wilson, J. F., Rudan, I., Campbell, H., Penninger, J. M., Sexl, V., Moriggl, R., van Duijn, C., Pramstaller, P. P., & Hicks, A. A. (2011). Variants in STAT5B associate with serum TC and LDL-C levels. Journal of Clinical Endocrinology & Metabolism, 96(9), E1496-501. https://doi.org/10.1210/jc.2011-0322

Smit, M. D., Crijns, H. J. G. M., Tijssen, J. G. P., Hillege, H. L., Alings, M., Tuininga, Y. S., Groenveld, H. F., Van den Berg, M. P., van Veldhuisen, D. J., & Van Gelder, I. C. (2011). Effect of Lenient Versus Strict Rate Control on Cardiac Remodeling in Patients With Atrial Fibrillation. Journal of the American College of Cardiology, 58(9), 942-949. https://doi.org/10.1016/j.jacc.2011.04.030

van Drongelen, J., Pertijs, J., Wouterse, A., Hermsen, R., Sweep, F. C. G. J., Lotgering, F. K., Smits, P., & Spaanderman, M. E. A. (2011). Contribution of different local vascular responses to mid-gestational vasodilation. American Journal of Obstetrics and Gynecology, 205(2), Article 155.e12. https://doi.org/10.1016/j.ajog.2011.03.020

Torp-Pedersen, C., Crijns, H. J. G. M., Gaudin, C., Page, R. L., Connolly, S. J., & Hohnloser, S. H. (2011). Impact of dronedarone on hospitalization burden in patients with atrial fibrillation: results from the ATHENA study. EP Europace, 13(8), 1118-1126. https://doi.org/10.1093/europace/eur102

van den Wijngaard, A., Volders, P., van Tintelen, J. P., Jongbloed, J. D. H., van den Berg, M. P., Deprez, R. H. L., Mannens, M. M. A. M., Hofmann, N., van Slegtenhorst, M., Dooijes, D., Michels, M., Arens, Y., Jongbloed, R., & Smeets, B. J. M. (2011). Recurrent and founder mutations in the Netherlands: cardiac Troponin I (TNNI3) gene mutations as a cause of severe forms of hypertrophic and restrictive cardiomyopathy. Netherlands Heart Journal, 19(7-8), 344-351. https://doi.org/10.1007/s12471-011-0135-z

Camm, A. J., Breithardt, G., Crijns, H., Dorian, P., Kowey, P. R., Le Heuzey, J.-Y., Merioua, I., Pedrazzini, L., Prystowsky, E. N., Schwartz, P. J., Torp-Pedersen, C., & Weintraub, W. S. (2011). Real-Life Observations of Clinical Outcomes With Rhythm- and Rate-Control Therapies for Atrial Fibrillation RECORDAF (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation). Journal of the American College of Cardiology, 58(5), 493-501. https://doi.org/10.1016/j.jacc.2011.03.034

Weber, C., Meiler, S., Doering, Y., Koch, M., Drechsler, M., Megens, R. T. A., Rowinska, Z., Bidzhekov, K., Fecher, C., Ribechini, E., van Zandvoort, M. A. M. J., Binder, C. J., Jelinek, I., Hristov, M., Boon, L., Jung, S., Korn, T., Lutz, M. B., Foerster, I., ... Zernecke, A. (2011). CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. Journal of Clinical Investigation, 121(7), 2898-2910. https://doi.org/10.1172/JCI44925

Foley, P. W. X., Chalil, S., Ratib, K., Smith, R., Prinzen, F., Auricchio, A., & Leyva, F. (2011). Fluoroscopic Left Ventricular Lead Position and the Long-Term Clinical Outcome of Cardiac Resynchronization Therapy. Pacing and Clinical Electrophysiology, 34(7), 785-797. https://doi.org/10.1111/j.1540-8159.2011.03114.x

Demirkan, A., Amin, N., Isaacs, A., Jarvelin, M.-R., Whitfield, J. B., Wichmann, H.-E., Kyvik, K. O. H. M., Rudan, I., Gieger, C., Hicks, A. A., Johansson, Å., Hottenga, J.-J., Smith, J. J., Wild, S. H., Pedersen, N. L., Willemsen, G., Mangino, M., Hayward, C., Uitterlinden, A. G., ... ENGAGE Consortium (2011). Genetic architecture of circulating lipid levels. European Journal of Human Genetics, 19(7), 813-9. https://doi.org/10.1038/ejhg.2011.21

La Meir, M., Gelsomino, S., Luca, F., Pison, L., Chambille, P., Parise, O., Crijns, H. J., & Maessen, J. G. (2011). Time-Related Prevalence of Postoperative Atrial Fibrillation After Stand-Alone Minimally Invasive Radiofrequency Ablation. Journal of Cardiac Surgery, 26(4), 453-459. https://doi.org/10.1111/j.1540-8191.2011.01272.x

Cox, M. G. P. J., van der Zwaag, P. A., van der Werf, C., van der Smagt, J. J., Noorman, M., Bhuiyan, Z. A., Wiesfeld, A. C. P., Volders, P. G. A., van Langen, I. M., Atsma, D. E., Dooijes, D., van den Wijngaard, A., Houweling, A. C., Jongbloed, J. D. H., Jordaens, L. J. L. M., Cramer, M. J., Doevendans, P. A., de Bakker, J. M. T., Wilde, A. A. M., ... Hauer, R. N. W. (2011). Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy: Pathogenic Desmosome Mutations in Index-Patients Predict Outcome of Family Screening: Dutch Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Genotype-Phenotype Follow-Up Study. Circulation, 123(23), 2690-2700. https://doi.org/10.1161/CIRCULATIONAHA.110.988287

Leyva, F., Foley, P. W. X., Chalil, S., Ratib, K., Smith, R. E. A., Prinzen, F., & Auricchio, A. (2011). Cardiac resynchronization therapy guided by late gadolinium-enhancement cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 13(1), 9. https://doi.org/10.1186/1532-429X-13-29

Strik, M., Ploux, S., Vernooy, K., & Prinzen, F. W. (2011). Cardiac Resynchronization Therapy - Refocus on the Electrical Substrate. Circulation Journal, 75(6), 1297-1304. https://doi.org/10.1253/circj.CJ-11-0356

Postema, P. G., Christiaans, I., Hofman, N., Alders, M., Koopmann, T. T., Bezzina, C. R., Loh, P., Zeppenfeld, K., Volders, P. G. A., & Wilde, A. A. M. (2011). Founder mutations in the Netherlands: familial idiopathic ventricular fibrillation and DPP6. Netherlands Heart Journal, 19(6), 290-296. https://doi.org/10.1007/s12471-011-0102-8

Laverty, H. G., Benson, C., Cartwright, E. J., Cross, M. J., Garland, C., Hammond, T. R., Holloway, C., McMahon, N., Milligan, J., Park, B. K., Pirmohamed, M., Pollard, C., Radford, J., Roome, N., Sager, P., Singh, S., Suter, T., Suter, W., Trafford, A. W., ... Valentin, J. P. (2011). How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?British Journal of Pharmacology, 163(4), 675-693. https://doi.org/10.1111/j.1476-5381.2011.01255.x

Zhou, Z., Subramanian, P., Sevilmis, G., Globke, B., Soehnlein, O., Karshovska, E., Megens, R., Heyll, K., Chun, J., Saulnier-Blache, J. S., Reinholz, M., van Zandvoort, M., Weber, C., & Schobert, A. (2011). Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium. Cell Metabolism, 13(5), 592-600. https://doi.org/10.1016/j.cmet.2011.02.016

van Geldorp, I. E., Vanagt, W. Y., Prinzen, F. W., & Delhaas, T. (2011). Chronic ventricular pacing in children: toward prevention of pacing-induced heart disease. Heart Failure Reviews, 16(3), 305-314. https://doi.org/10.1007/s10741-010-9207-1

Cornelussen, R. N., Splett, V., Klepfer, R. N., Stegemann, B., Kornet, L., & Prinzen, F. W. (2011). Electrical modalities beyond pacing for the treatment of heart failure. Heart Failure Reviews, 16(3), 315-325. https://doi.org/10.1007/s10741-010-9206-2

Dinh, T., Baur, L. H. B., Pisters, R., Kamp, O., Verheugt, F. W. A., Smeets, J. L. R. M., Cheriex, E. C., Tieleman, R. G., Prins, M. H., & Crijns, H. J. G. M. (2011). Feasibility of TEE-guided stroke risk assessment in atrial fibrillation-background, aims, design and baseline data of the TIARA pilot study. Netherlands Heart Journal, 19(5), 214-222. https://doi.org/10.1007/s12471-011-0095-3

Megens, R. T. A., Kemmerich, K., Pyta, J., Weber, C., & Soehnlein, O. (2011). Intravital imaging of phagocyte recruitment. Thrombosis and Haemostasis, 105(5), 802-810. https://doi.org/10.1160/TH10-11-0735

Heijman, J., Volders, P. G. A., Westra, R. L., & Rudy, Y. (2011). Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient. Journal of Molecular and Cellular Cardiology, 50(5), 863-871. https://doi.org/10.1016/j.yjmcc.2011.02.007

Christiaans, I., Birnie, E., Bonsel, G. J., Mannens, M. M. A. M., Michels, M., Majoor-Krakauer, D., Dooijes, D., van Tintelen, J. P., Van den Berg, M. P., Volders, P. G. A., Arens, Y. H., van den Wijngaard, A., Atsma, D. E., Helderman-van den Enden, A. T. J. M., Houweling, A. C., de Boer, K., van der Smagt, J. J., Hauer, R. N. W., Marcelis, C. L. M., ... Wilde, A. A. M. (2011). Manifest disease, risk factors for sudden cardiac death, and cardiac events in a large nationwide cohort of predictively tested hypertrophic cardiomyopathy mutation carriers: determining the best cardiological screening strategy. European Heart Journal, 32(9), 1161-1170. https://doi.org/10.1093/eurheartj/ehr092

Prinzen, F. W., Vernooy, K., DeBoeck, B. W. L., & Delhaas, T. (2011). Mechano-energetics of the asynchronous and resynchronized heart. Heart Failure Reviews, 16(3), 215-224. https://doi.org/10.1007/s10741-010-9205-3

Koetje, P. M., Spaan, J. J., Kooman, J. P., Spaanderman, M. E. A., & Peeters, L. L. H. (2011). Pregnancy Reduces the Accuracy of the Estimated Glomerular Filtration Rate Based on Cockroft-Gault and MDRD Formulas.Reproductive Sciences, 18(5), 456-462. https://doi.org/10.1177/1933719110387831

Scholten, R. R., Sep, S., Peeters, L., Hopman, M. T. E., Lotgering, F. K., & Spaanderman, M. E. A. (2011). Prepregnancy Low-Plasma Volume and Predisposition to Preeclampsia and Fetal Growth Restriction. Obstetrics and Gynecology, 117(5), 1085-1093. https://doi.org/10.1097/AOG.0b013e318213cd31

Page, R. L., Connolly, S. J., Crijns, H. J. G. M., van Eickels, M., Gaudin, C., Torp-Pedersen, C., & Hohnloser, S. H. (2011). Rhythm- and Rate-Controlling Effects of Dronedarone in Patients With Atrial Fibrillation (from the ATHENA Trial). American Journal of Cardiology, 107(7), 1019-1022. https://doi.org/10.1016/j.amjcard.2010.11.028

De Ferrari, G. M., Crijns, H. J. G. M., Borggrefe, M., Milasinovic, G., Smid, J., Zabel, M., Gavazzi, A., Sanzo, A., Dennert, R., Kuschyk, J., Raspopovic, S., Klein, H., Swedberg, K., & Schwartz, P. J. (2011). Chronic vagus nerve stimulation: a new and promising therapeutic approach for chronic heart failure. European Heart Journal, 32(7), 847-855. https://doi.org/10.1093/eurheartj/ehq391

Alzand, B. S. N., & Crijns, H. J. G. M. (2011). Diagnostic criteria of broad QRS complex tachycardia: decades of evolution. EP Europace, 13(4), 465-472. https://doi.org/10.1093/europace/euq430

van Rijsingen, I. A. W., Bekkers, S. C. A. M., Schalla, S., Hermans-van Ast, J. F., Snoep, G., Alzand, B. S. N., Arens, Y. H. J. M., van den Wijngaard, A., Crijns, H. J. G. M., & Pinto, Y. M. (2011). Exercise related ventricular arrhythmias are related to cardiac fibrosis in hypertrophic cardiomyopathy mutation carriers. Netherlands Heart Journal, 19(4), 168-174. https://doi.org/10.1007/s12471-011-0090-8

Kirchhof, P., Kahr, P. C., Kaese, S., Piccini, I., Vokshi, I., Scheld, H.-H., Rotering, H., Fortmueller, L., Laakmann, S., Verheule, S., Schotten, U., Fabritz, L., & Brown, N. A. (2011). PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression. Circulation : Cardiovascular Genetics, 4(2), 123-U84. https://doi.org/10.1161/CIRCGENETICS.110.958058

ACCF/AHA TASK FORCE MEMBERS, & Crijns, H. (2011). 2011 ACCF/AHA/HRS Focused Update on the Management of Patients with Atrial Fibrillation (Update on Dabigatran): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation, 123(10), 1144-1150. https://doi.org/10.1161/CIR.0b013e31820f14c0

Fuster, V., Ryden, L. E., Cannom, D. S., Crijns, H. J., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Kay, G. N., Le Huezey, J.-Y., Lowe, J. E., Olsson, S. B., Prystowsky, E. N., Tamargo, J. L., Wann, L. S., Estes, N. A. M. III., Ezekowitz, M. D., Jackman, W. M., January, C. T., Page, R. L., ... Yancy, C. W. (2011). 2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines 2006 WRITING COMMITTEE MEMBERS Developed in partnership with the European Society of Cardiology and in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Journal of the American College of Cardiology, 57(11), E101-E198. https://doi.org/10.1016/j.jacc.2010.09.013

Wann, L. S., Curtis, A. B., Ellenbogen, K. A., Estes, N. A. M. III., Ezekowitz, M. D., Jackman, W. M., January, C. T., Lowe, J. E., Page, R. L., Slotwiner, D. J., Stevenson, W. G., Tracy, C. M., Fuster, V., Ryden, L. E., Cannom, D. S., Crijns, H. J., Halperin, J. L., Kay, G. N., Le Heuzey, J.-Y., ... Yancy, C. W. (2011). 2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Update on Dabigatran) A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Heart Rhythm, 8(3), E1-E8. https://doi.org/10.1016/j.hrthm.2011.01.032

Greiser, M., Lederer, W. J., & Schotten, U. (2011). Alterations of atrial Ca2+ handling as cause and consequence of atrial fibrillation. Cardiovascular Research, 89(4), 722-733. https://doi.org/10.1093/cvr/cvq389

Brugts, J. J., Isaacs, A., de Maat, M. P., Boersma, E., van Duijn, C. M., Akkerhuis, K. M., Uitterlinden, A. G., Witteman, J. C., Cambien, F., Ceconi, C., Remme, W., Bertrand, M., Ninomiya, T., Harrap, S., Chalmers, J., Macmahon, S., Fox, K., Ferrari, R., Simoons, M. L., & Danser, A. J. (2011). A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals. Journal of Hypertension, 29(3), 509-19. https://doi.org/10.1097/HJH.0b013e328341d117

Obermann-Borst, S. A., Isaacs, A., Younes, Z., van Schaik, R. H. N., van der Heiden, I. P., van Duyn, C. M., Steegers, E. A. P., & Steegers-Theunissen, R. P. M. (2011). General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect. American Journal of Obstetrics and Gynecology, 204(3), 236.e1-8. https://doi.org/10.1016/j.ajog.2010.10.911